A personal journey to self-help and healing via ayahuasca -- the most powerful psychedelic known to man. Life and death, heaven and hell, salvation and damnation... there are no higher stakes that we know of in this universe. Come with me on my journey.
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BrainPod is the podcast from the journal Neuropsychopharmacology, produced in association with Nature Publishing Group. Join us as we delve into the latest basic and clinical research that advance our understanding of the brain and behavior, featuring highlighted content from a top journal in fields of neuroscience, psychiatry, and pharmacology. For complete access to the original papers and reviews featured in this podcast, subscribe to Neuropsychopharmacology. Hosted on Acast. See acast.co ...
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In this, my final rebuttal episode from the debate I had, we will explore how knowing God changes the equation of love. Support the showBy Journeyman
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Grey matter morphometry in young adult e-cigarette users, tobacco cigarette users & non-using controls
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8:45There’s been a fair amount of animal data suggesting that nicotine can affect the developing brain, but there hadn’t been the equivalent human studies done on people whose brains are still developing. And today there are two predominant forms of nicotine delivery - tobacco cigarettes, and e-cigarettes, or vaping. Laurie Zawertailo is a senior scien…
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Validation of L-type calcium channel blocker amlodipine as a novel ADHD treatment through cross-species analysis, drug-target Mendelian randomization, and clinical evidence from medical records
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9:41Attention deficit hyperactivity disorder, or ADHD, is a common condition that, for a lot of people, is difficult to treat. The drugs that exist have a number of adverse side effects, and about 25 percent of patients don’t respond to existing drugs. And so a team of researchers in Iceland, led by Karl Karlsson, professor of biomolecular engineering …
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Is it possible to believe in God while not believing in God? Let's find out. Support the showBy Journeyman
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In this episode, I face a critic head-on. More to come. Support the showBy Journeyman
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Rapid and sustained antidepressant effects of vaporized N,N-Dimethyltryptamine: A Phase 2a clinical trial in Treatment-Resistant Depression.
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9:52Draulio Araujo, professor at the Brain Institute in the University of Rio Grande Norte in Natal, Brazil, has been studying ayahuasca for more than 20 years. It’s a psychedelic plant used in rituals in South America that has also been researched for its potential to treat depression. The effects of ayahuasca can last for hours and also lead to side …
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Endocannabinoid contributions to the perception of socially relevant, affective touch in humans
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9:13New drugs that target the endocannabinoid system are being proposed for disorders that are usually characterized by the dysregulation of social processing, like social anxiety disorder and autism spectrum disorder. Researchers have been trying to understand the mechanisms for how these drugs work. Leah Mayo is assistant professor at the University …
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Sex differences in sensitivity to dopamine receptor manipulations of risk-based decision making in rats
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9:46
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9:46The scientific literature has shown that females demonstrate more aversion to risk-taking than males. Studies have also demonstrated that the basal lateral amygdala, or BLA, is a critical hub for processing risk and reward information. And yet further research has shown that activity in the amygdala differs between males and females, and that the e…
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Biomarker development for menstrual Cycle affective change: the need for greater temporal, mechanistic, and phenotypic specificity.
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9:39
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9:39The menstrual cycle is known to affect things like mood and changes in pain. But there can also be symptoms that have a serious impact on a person’s function, ability to work, ability to maintain friendships and romantic relationships. This is a rare condition known as premenstrual dysphoric disorder. But it’s not the only psychiatric condition tha…
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In this episode, we dive into the concepts of value and what really matters in life versus what doesn't. Spoiler alert! There is a central truth behind everything in existence which can never be lost. It can only be found. Support the showBy Journeyman
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In this episode, I answer the ageless question that has been haunting human beings since the dawn of time. If God exists and is all loving and all powerful, why does evil exist. Get ready for an answer that will blow your mind. Support the showBy Journeyman
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Genome-wide association studies of coffee intake in UK/US participants of European ancestry uncover cohort-specific genetic associations
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9:39Researchers are interested in understanding the biology of why some people are more likely to overconsume substances. Some substances are difficult to study—people might not admit to illegal substance abuse or to how much alcohol they drink. But Americans are more likely to accurately recall and share how much coffee they drink—which is related to …
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Truth Be Told - The Truth About Synchronicity
2:03:02
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2:03:02In this episode we dive as deep as possible into the mind-bending concept of synchronicity. Is it just chaos and pure coincidence or are there beyond-cosmic tie-ins? Is it God? Is it predestination? Is it all of the above? We will find out on this episode. Support the showBy Journeyman
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It's time to catch you up on some of my latest developments... synchronicities abound!! Support the showBy Journeyman
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Psychedelics and Addiction - Andrew's Story
1:29:28
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1:29:28Does psychedelics cure addiction? Well, it depends on who you ask. Removing all of the hype and platitudes, Hugo and Andrew sit down to cut through the fog of addiction, recovery, psychedelics, God, and how it all pieces together This a collaboration with "My Journey Through the Pantheos" and "The 1% in Recovery Podcast" Hugo Vrsalovic is the found…
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C-reactive protein moderates associations between racial discrimination and ventromedial prefrontal cortex activation during attention to threat in Black American women
9:56
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9:56Scientists have been amassing an increasing amount of evidence about the impact of racial discrimination and racial trauma, including how it can have an impact on brain regions involved with threat vigilance and emotional regulation. At the same time, there’s evidence that increased engagement in those areas has been linked to increased risk of men…
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Trip 15 - Forgive, Listen, Cry, Repeat
1:51:49
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1:51:49Here it is... the trip that broke me... in all its splendor and glory Support the showBy Journeyman
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Ghrelin decreases sensitivity to negative feedback and increases prediction-error related caudate activity in humans, a randomized controlled trial
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9:06There’s a hormone called ghrelin that’s secreted in the stomach, and when someone is hungry it contributes to that feeling of hunger and the need to search for food. But neurological studies have suggested that ghrelin might also play a role in compulsivity and impulsivity, and it might be related to substance use disorders. Rebecca Boeme is an ass…
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Have you ever been in a train wreck? No? Well, brace yourself for one. Support the showBy Journeyman
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Please pray for my unborn daughter Support the showBy Journeyman
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Spotlighting SHAPERS: Sex hormones associated with psychological and endocrine roles
9:08
9:08
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9:08Dr. Nicole Petersen is an assistant professor in the department of psychiatry and behavioral sciences at UCLA. Her commentary is a new paper in the journal Neuropsychopharmacology, called “Spotlighting SHAPERS: sex hormones associated with psychological and endocrine roles.” Dr. Petersen starts the paper describing an unnamed signaling molecule tha…
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In part one of my series on astral projection we hear from my friend Becky... someone who happened upon astral projection accidentally and dared to explore further Support the showBy Journeyman
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Comparable roles for serotonin in rats and humans for computations underlying flexible decision-making
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9:33Serotonin is a critical chemical when it comes to a number of psychiatric conditions, such as OCD, where it seems to play a particular role in cognitive flexibility. That is, serotonin levels are related to the fact that someone is perseverating on intrusive thoughts or compulsions and isn’t able to be as flexible as otherwise would be necessary. T…
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Today we are revisiting the Gateway Program, aliens, and The Galactic Federation to kickoff a series of upcoming episodes I will be releasing about astral projection. I have added A LOT more to this amazing story; so sit back and enjoy the ride! Support the showBy Journeyman
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Today we dive deep into the depths of what we truly are. How much of the divine is truly in us? Let's investigate and find out! Support the showBy Journeyman
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Integrating public health and translational basic science to address challenges of xylazine adulteration of fentanyl
9:58
9:58
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9:58The drug naloxone, otherwise known as Narcan, is a critical tool in reversing fentanyl overdoses and reducing mortality. But now fentanyl is appearing on the streets adulterated with a drug called xylazine. Justin Strickland, assistant professor at Johns Hopkins University School of Medicine, and Cassandra Gipson-Reichardt, associate professor in t…
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Who's there? It could be anyone with any motive. Protect yourself and let the right one in. Support the showBy Journeyman
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In this episode we get sucked into the flow and we flow with it... oh, and more proof of Jesus Support the showBy Journeyman
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In this episode, we dive straight to the paradoxical heart of truth. Support the showBy Journeyman
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The why, when, where, how, and so what of so-called rapidly acting antidepressants
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8:29
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8:29Sanjay Mathew is a professor and vice chair for research at Baylor College of Medicine and director of the Mood and Anxiety Disorders Program. He’s one of the two authors of a recent review paper in the journal Neuropsychopharmacology, “The why, when, where, how, and so what of so-called rapidly acting antidepressants.” With his colleague Alan Scha…
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A literal miracle happened today... listen for yourself Support the showBy Journeyman
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Do not listen to this. Nothing of importance here. Listen if you're dead.
1:58:11
1:58:11
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1:58:11Celebrating 900 subs yall! That's it. There is nothing special about this episode. Listen only if you're dead. Support the showBy Journeyman
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Is the beauty of existence a trap? On this episode of My Journey Through the Pantheos, we dive deep into the joke of life and test the limits. Support the showBy Journeyman
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There are no words to describe this trip. It's simply beyond belief. But you know me, I'm going to describe it anyway. In this one we get transported back to the dawn of time, we see a slice of heaven, shake hands with God, we get attacked by a witch, and we see the birth and evolution of the universe. Strap in! Support the show…
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AI-based analysis of social media language predicts addiction treatment dropout at 90 days
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9:09In-person treatment for substance use disorders is an incredibly important tool, but there’s a high failure rate — more than 50 percent of people who enter drop out within the first month. There hasn’t been a highly accurate method of identifying who might leave and who might succeed, and knowing this could help centers allocate resources to give t…
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Oxytocin effects on amygdala reactivity to angry faces in males and females with ASPD
9:27
9:27
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9:27Antisocial personality disorder, or ASPD, is a difficult disorder to study. There have been studies on psychopathic individuals, and on youth with psychopathic traits, but most studies on ASPD to date have been on incarcerated adults. A team of researchers at Heidelberg University wanted to study individuals who are not incarcerated and see what th…
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Have you ever wondered why there are so many theories and explanations for existence? The ballot box is being stuffed. Trust no one but yourself. But watch out. Support the showBy Journeyman
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To dismantle structural racism in science, scientists need to learn how it works
9:54
9:54
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9:54It’s clear there are diversity issues in science, both in terms of who does or doesn’t receive research grants, as well as who is or isn’t represented at the highest levels of scientific research. When Caleb Weinreb and Daphne Sun began their PhD program at Harvard University Medical School in systems biology, they took this on as an issue. They le…
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In this episode, we get punched in the nose, scarred by the riddle of faith Support the showBy Journeyman
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In this episode we will touch the face of death. And of course, we will realize that it is a big joke. Support the showBy Journeyman
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If you're wondering how it's going, I tell you in this episode. Support the showBy Journeyman
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Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity
9:59
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9:59Psychedelic drugs have received attention recently for their potential use as treatments for psychiatric disorders. Single, high doses of LSD have shown promise for treating depressive disorders. But there’s another way in which people have been using LSD, and it’s what’s known as micro-dosing, taking LSD at below noticeable levels, where it doesn’…
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Sex-dependent risk factors for PTSD: a prospective structural MRI study
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9:29After a traumatic event, women are more likely to be diagnosed with post-traumatic stress disorder, or PTSD. Research has been conducted on what might be causing this higher rate of diagnoses; for instance, perhaps women had more cumulative trauma in their lives than the men in question. But scientists say that even taking prior childhood trauma in…
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The stakes have just been upped... the assassins of the cosmic spiritual war are clearly after me... and they're after you too. But there is good news. Infinitely good news. Support the showBy Journeyman
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In this episode we dive even deeper into the fathomless--infinity itself. With both scope and scale being understood, we examine the details, the specifics of what is "going on" within... and what we find there is unspeakably terrifying. Support the showBy Journeyman
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In this insanely epic unpacking episode, we peel the onion on the infinite to explore the waves of God's true form that I experienced on my last ayahuasca trip. Support the showBy Journeyman
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Sex differences in appetitive and reactive aggression
9:47
9:47
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9:47Maladaptive aggression, while not a diagnosable neuropsychiatric disorder on its own, often presents as an important comorbid condition with other neuropsychiatric disorders. But while both men and women can and do display aggression, there’s been a bias to thinking of aggression, in both its adaptive and maladaptive forms, as a male behavior. Sam …
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Let me ask you a question... do you think you know what infinity is? Have you ever sat back and pondered what infinity really is? Well, if you've pondered and fell short of the answer, prepare to be delivered unto the answer of all answers... the answer to existence... the answer to the end... the answer to everything... the answer to infinity. But…
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What’s wrong with my experiment?: The impact of hidden variables on neuropsychopharmacology research
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9:34
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9:34Sometimes, when researchers are conducting an experiment, the results are confusing. Maybe the control group of animals doesn’t behave the way a control should in theory be behaving. Maybe a researcher repeats a study and sees results that are unusually different from the first time around. The answers to these issues might lie in something called …
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This episode is a companion piece to the previous episode "The Reason". In this episode we dive deeper into science vs. religion to find some middle ground and in so doing, we encounter A.I. Jesus. Support the showBy Journeyman
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