Best Docs In Orbit Podcasts (2025)

1
🧬 Silencing Risk: Lepodisiran vs Lp(a) 4:12

7h ago4:12

4:12

🚨 New hope for high Lp(a)! 💉 Lepodisiran, a long-acting siRNA, slashed Lp(a) by 94% with just 2 shots/year. 🔬 RNA precision meets cardiac prevention. 📉 Silent killer, silenced. #CardioTwitter #RNAtherapy #LipoproteinABy MasterMedFacts LLC

1
💨 Breathing Battles: Navigating COPD Phenotypes 4:15

4h ago4:15

4:15

🌬️🚶‍♂️ COPD comes in many forms! From chronic bronchitis 🪫 to emphysema 💨, frequent exacerbators 🚨, asthma-COPD overlap 🌪️, and eosinophilic type 🧫. Tailoring treatment to phenotype is key! #COPD #PrecisionMedicine #RespiratoryCareBy MasterMedFacts LLC

1
💊 TANDEM Triumph: Dual Power for LDL Cholesterol Reduction! 4:45

22h ago4:45

4:45

🚀 TANDEM Trial: Combining Obicetrapib & Ezetimibe for a powerful LDL reduction! 💊 ✅ -48.6% vs placebo, -27.9% vs Ezetimibe, -16.8% vs Obicetrapib 💪 Safe, effective, and oral! #Cardiology #LipidManagement #ASCVDBy MasterMedFacts LLC

1
Fungal Pharmacists, Fatty Liver, Future Frontiers 🧬🩸🍄 4:27

1d ago4:27

4:27

A gut fungus 🍄 (Fusarium foetens) secretes FF-C1 🧪, a metabolite that inhibits CerS6 and lowers ceramides 🩸—shielding mice from MASH 🛡️. Fungi aren’t just freeloaders—they may be our next therapeutic allies! 💊🧠 #Microbiome #LiverHealth #FungalTherapy #ScienceBy MasterMedFacts LLC

1
💪 Powerful Cholesterol Control: Obicetrapib in the Spotlight 🌟 2:44

2d ago2:44

2:44

🚀 Obicetrapib: A Breakthrough in LDL Lowering! 📉 Reduced LDL by 29.9% in high-risk patients (pBy MasterMedFacts LLC

1
Fat Chance! 🔬🧬 Middle-Age Spread Starts at the Cellular Level 3:13

2d ago3:13

3:13

Here’s a tweet with emojis based on the article: 🧬 Middle-age spread decoded! 🕰️ Visceral fat grows in midlife not from bigger cells—but new ones! 🎯 CP-A cells fire up fat formation via LIFR–STAT3 🔥 💊 Targeting them may halt metabolic disease before it starts. #Aging #Obesity #CellBiology #Metabolism 🧫 Would you like a version with a more humorous …

1
🔍📊🛡️ Detect, Decode, Defend: A New Era in Coronary Risk Prediction 3:31

3d ago3:31

3:31

🚨 New era in heart disease prediction! 🧬 + 🧪 + 🤖 = Meta-prediction model that beats PCE & QRISK3 📈 Detects hidden CAD risk in young, women & “low-risk” groups 🎯 Precision prevention just got personal. 🫀 Published in Nature Medicine #CardioTwitter #AI #Genomics #CADBy MasterMedFacts LLC

1
Dr RR Baliga's Philosophical Discourses: Epicurus (Greece, 341–270 BCE) – Founder of Epicureanism 3:16

3d ago3:16

3:16

Epicurus (341–270 BC) was an ancient Greek philosopher who founded Epicureanism, emphasizing the pursuit of a tranquil, happy life through ataraxia (freedom from fear) and aponia (absence of pain). His teachings combined atomism, ethics, and naturalistic theology, advocating simple living, friendship, and the rejection of superstition.…

1
Calcium Wars: Orbital Atherectomy vs. Balloon Angioplasty — The ECLIPSE Verdict ⚔️🧠💔 3:36

4d ago3:36

3:36

🚨ECLIPSE Trial Results🚨 Orbital atherectomy 🌀 vs. balloon angioplasty 🎈 before stenting in severe coronary calcification 💔 🎯 No added benefit with atherectomy 🧠 Balloon-first + imaging = smart strategy 📊 Lancet 2025 | #CardioTwitter #InterventionalCardiology #ECLIPSETrialBy MasterMedFacts LLC

1
Genes 🧬, Journeys 🌍, and Hidden Hazards ⚡: Unlocking Health with Exposomics 2:53

4d ago2:53

2:53

“Your DNA 🧬 is just half the story — your exposome 🌍 writes the rest! From air 🌫️ to food 🍎 to stress 😰, exposomics unlocks the hidden drivers of health 🔍💥. Predict. Prevent. Prosper. 🚀 #Exposomics #PrecisionMedicine”By MasterMedFacts LLC

1
. 🧩📉 “Unstiff the Heart: Cracking the Code of Cardiac Scars” 🫀🧬 2:29

5d ago2:29

2:29

🫀💊 Scientists found a way to trick heart cells into calming down! Blocking stiffness signals with a smart drug combo reduced scarring and helped hearts pump better in mice. A big step toward #mechanotherapy! 🧠🔬🐭 #CardioTwitter #Fibrosis #HeartHealthBy MasterMedFacts LLC

1
“Hope or Hype? Surveillance, Survival, and the Truth About Metastases 🔬⚖️🕯️” 3:04

5d ago3:04

3:04

🧪 Routine scans after cancer treatment: lifesaver or false security? 😰 Evidence shows no survival benefit, but lots of scanxiety, cost, and early toxicity. 💡 Sometimes, less is more. Ask why before you scan. #CancerSurveillance #Oncology 🩺📉By MasterMedFacts LLC

1
🕒💔 Heartbeats in Time: How Your Body Clock Protects Your Heart 3:18

6d ago3:18

3:18

⏰🫀 Your heart heals differently depending on the time of day! A protein duo—BMAL1 + HIF2α—peaks in the afternoon, boosting AREG, a heart repair helper. 💔 Morning heart attacks? Worse outcomes. 🕒 Timing meds = better healing. #Chronotherapy #HeartHealth #CircadianScienceBy MasterMedFacts LLC

1
🐍 The Man Who Took 200 Snake Bites… and Helped Save Lives! 2:37

6d ago2:37

2:37

🧬💉 Bitten 200+ times, one man’s blood helped create a universal antivenom! 🦸‍♂️🐍 Human antibodies + varespladib = protection from 19 deadly snake venoms 🛡️🔥 Science just took a big bite out of snakebite! 🌍🔬 #Snakebite #Antivenom #InnovationBy MasterMedFacts LLC

1
Running, Risk, and Rescue: Contemporary Insights into Cardiac Arrest in Distance Races 4:14

7d ago4:14

4:14

🏃‍♂️ Cardiac arrests in marathons stable, but deaths cut in half! 🫀 CAD now the top cause, not HCM. 🚑 Quick CPR + AED saves lives. 📈 Poisson stats confirm the trends! #Running #HeartHealth #MarathonMedicineBy MasterMedFacts LLC

1
Brains, Bots, and Balance: Cracking Moravec’s Paradox 🧩🦾🧠 3:07

7d ago3:07

3:07

🤖 Moravec’s Paradox shows that what’s easy for humans—like walking, seeing, or grasping—is hard for AI, while abstract tasks like math or chess are easier for machines. 🧠 Evolution honed our sensorimotor skills over millennia, making them intuitive for us but deeply complex to replicate in code. 🚶‍♂️ So while AI can solve equations, it still stumbl…

1
Lorundrostat’s Promise for Persistent Hypertension 3:22

8d ago3:22

3:22

🚀 Lorundrostat lowers 24-hour systolic BP in resistant hypertension! 🎯 🔬 Selective aldosterone synthase inhibition shows promise but watch for hyperkalemia ⚠️ 🌟 New hope for tough-to-treat BP! #Hypertension #Cardiology #NEJMBy MasterMedFacts.com

1
MASH Gets Mashed: Fibrosis Falls, Liver Up, Hopes Rise 💪🧬🚀 4:06

9d ago4:06

4:06

Semaglutide 2.4 mg weekly led to significant resolution of MASH and reduction in fibrosis after 72 weeks 🌟🧬. Patients lost more weight ⚖️, showed better liver markers 📉, and had improved metabolic profiles 💉. GI side effects were common 🤢, but no new safety signals emerged ✅. Promising dual-action therapy for liver and cardiometabolic health! ❤️🩺…

1
🥣 Feed. 💪 Heal. 🔄 Recover: Enteral Nutrition in Hospital Care 3:47

10d ago3:47

3:47

🏥 Enteral nutrition is a vital therapy for malnourished hospitalized adults, yet remains underused. 📉 It reduces mortality, readmissions, and complications when oral intake is inadequate. 🧪 Trials show early full feeding may harm in critical illness—underfeeding can be safer. 🧠 Success depends on timing, dose, route, and a team-based, patient-cente…

1
Dr RR Baliga's Philosophical Discourses: Mencius (China, c. 372–289 BCE) – Confucian Philosopher 3:22

11d ago3:22

3:22

Mencius (c. 371–289 BC) was a prominent Confucian philosopher known as the “Second Sage” after Confucius. He emphasized the innate goodness of human nature, advocating for humane governance, moral cultivation, and the welfare of citizens. His teachings greatly influenced Confucianism and later Neo-Confucian thought.…

1
Mutants, Mitochondria & Metformin 🔬🔋💊: Powering Down Clonal Haematopoiesis 2:59

12d ago2:59

2:59

🧬 Clonal haematopoiesis (CH)—especially with DNMT3A-R882 mutations—increases with age and raises leukemia risk. 💊 New studies reveal that metformin targets mutant blood stem cells by suppressing mitochondrial metabolism, sparing healthy cells. 📉 UK Biobank data shows lower CH prevalence in metformin users. 🔋 Targeting oxidative phosphorylation may …

1
A Shot 💉 at Memory 🧠: Can Diabetes Drugs Fight Forgetfulness ❓ 3:10

13d ago3:10

3:10

In this large real-world study 🧪 using electronic health records 📊, GLP-1RAs and SGLT2is—two diabetes drugs 💉—were associated with a lower risk of Alzheimer’s and related dementias 🧠 in people with type 2 diabetes 🍬. Both showed protective effects 🛡️, with no significant difference between them, suggesting promise for drug repurposing ♻️ in brain h…

1
Sweat 💦, Synapses 🧠, Survival 🛡️: Exercise and the Ageing Brain 4:10

14d ago4:10

4:10

🧠 Regular endurance exercise boosts brain health by increasing blood flow 💓, enhancing neuroplasticity 🔁, and reducing inflammation 🔥. 🏃‍♂️ High cardiorespiratory fitness (CRF) lowers dementia risk 🧩, supports memory 📝, and promotes the release of powerful brain molecules like BDNF 🧬 and irisin 💪. ✨ In short: Move more, age slower, think sharper!…

1
🔬 Cataracts Decoded: Clarity, Surgery, and the Silver Years 👓” 2:57

15d ago2:57

2:57

👁️ Cataracts are a common cause of vision loss in older adults, leading to blurry vision, glare, and difficulty with daily tasks. 💉 Surgery is safe, quick, and effective — restoring clarity, reducing fall risk, and even lowering dementia risk. 🔬 Advanced lenses can reduce dependence on glasses, while intraocular antibiotics help prevent rare infect…

1
Staph Aureus Bacteremia 🦠 Detect. 💊 Treat. 🔍 Control the Source!” 3:54

16d ago3:54

3:54

🦠 Staphylococcus aureus bacteremia (SAB) is a deadly bloodstream infection with high rates of complications like endocarditis and abscesses. 💉 Early detection, MRSA coverage with vancomycin/daptomycin, and source control (🪛 remove catheters, drain abscesses) are critical. 🔍 Use echocardiography and VIRSTA score to guide management. ✅ Once susceptib…

1
🧠 Fast Wins, Flawed Logic, Real Choices 2:20

17d ago2:20

2:20

🧠 People often say they want big wins (like lotteries), but in practice, they choose what wins more often—even if it pays less. 🎮 In experiments, when outcomes are shown side-by-side, we tend to favor the “frequent winner.” 📉 This bias can make us overlook rare, high rewards—shaping real-world choices in money, health, and risk. 🔍 Bottom line: It’s…

1
Dr. RR Baliga’s Philosophical Discourses: Zhuangzi (China, c. 369–286 BCE) – Taoist Philosopher 3:25

18d ago3:25

3:25

Zhuang Zhou, also known as Zhuangzi, was an influential 4th-century BCE Chinese philosopher during the Warring States period. As a foundational figure of Taoism, he authored the Zhuangzi, a text known for its profound philosophical insights, parables, and critiques of societal norms, emphasizing personal freedom and harmony with the Tao. His ideas …

1
Hands Down, Cream Wins! 🖐️🧴💥 Delgocitinib vs Alitretinoin in Chronic Eczema 3:56

19d ago3:56

3:56

🧴 Delgocitinib cream outperformed oral alitretinoin in treating severe chronic hand eczema over 24 weeks. 📉 Greater reduction in HECSI, 😊 better quality of life, and ⚠️ fewer side effects make it a promising non-steroidal alternative. 💊 Time to rethink systemic pills — topical wins hands down! 🖐️✅By MasterMedFacts LLC

1
🧠🦴🚼 “Brains, Balance, and Birth: Cracking the Pelvic Code 2:53

20d ago2:53

2:53

🧬 Human pelvic evolution reflects a tug-of-war between 🚶‍♀️ efficient walking, 🧠 growing brains, and 🚼 safe childbirth. Using AI and genetic data from 31,115 individuals, Xu et al. found the pelvis is highly heritable, sex-dimorphic, and shaped by multiple selective pressures—not just bipedalism or birth. Larger canals ease delivery but risk 💥 pelv…

1
🫁💥 “Lung Clues & Blood Blues: How Tiny Lung Vesicles Spark Deadly Cancer Clots” 🧬🩸 2:43

21d ago2:43

2:43

🩸 Summary: Lung interstitial macrophages, activated by tumor-derived CXCL13, release integrin β2⁺ extracellular vesicles (sEVs) 🧬 that bind platelet GPIb 🧲, triggering clot formation across the body. These sEVs are both a driver of cancer-associated thrombosis and a potential biomarker for early risk detection 🎯, offering safer, targeted therapeuti…

1
Inflammation 🔥, Dopamine 💊, and Apathy 😐: A Neuroimmune Pathway in Brain Fog? 3:30

22d ago3:30

3:30

Cancer cachexia isn’t just weight loss—it’s a hijacking of motivation 😔. Elevated IL-6 🔥 activates a brainstem-to-basal ganglia circuit 🧠 that suppresses dopamine 💊 in the nucleus accumbens, leading to effort-based apathy 💤. Blocking IL-6 or boosting dopamine restores drive without changing weight, revealing a treatable neuroimmune pathway 💡.…

1
“🧠 Fewer Strokes, 🚫 No Bleeds, ✅ Stronger Choice: Clopidogrel After PCI? 4:17

23d ago4:17

4:17

🧪 SMART-CHOICE 3 in a Nutshell 🟣 Clopidogrel beat 🟠 aspirin post-PCI: 📉 Fewer MACCE (4.4% vs 6.6%) 🩸 Same bleeding risk 🍽️ Fewer GI events ⚠️ Editorial: Fragile stats, late benefit, open questions on lifelong therapy. 🎯 Verdict: Promising—but not bulletproof.By MasterMedFacts

1
Mitochondria. Medicine. Miracles 2:31

24d ago2:31

2:31

🔋 Mitochondrial transplants are emerging as a powerful therapy to repair damaged cells, boost energy, and even reverse aging. From saving 🫀 baby hearts to protecting 🧠 stroke-affected brains, this tiny powerhouse may revolutionize medicine—one cell at a time. 🧬💉✨By MasterMedFacts LLC

1
Dr. RR Baliga’s Philosophical Discourses: Plato (Greece, 427–347 BCE) – Founder of the Academy 4:48

25d ago4:48

4:48

Plato (c. 428-348 BCE), a foundational figure in Western philosophy, was a student of Socrates and teacher of Aristotle. He established the Academy in Athens and is known for his theory of Forms, dialogues on justice, ethics, and politics, and lasting influence on philosophy, science, and education.By MasterMedFacts LLC

1
Mitochondria the Tiny Travelers, Big Impact, Bold Future 1:49

26d ago1:49

1:49

🧬 Mitochondria are on the move! Once thought to stay put, these powerhouses travel between cells 🚀—healing neurons 🧠, boosting immunity 🛡️, and even aiding cancer cells ⚠️. Scientists are now exploring how to harness this dynamic dance for future therapies 💉.By MasterMedFacts LLC

1
From Cold to Bold: The Legacy of Winter Conception 3:21

27d ago3:21

3:21

❄️ Conceived in the Cold? Individuals conceived during colder months show higher brown fat activity, increased thermogenesis, and lower BMI as adults. 🔬 Using PET/CT, NIR-TRS, and doubly labeled water (DLW), the study linked preconception cold exposure to greater energy expenditure and reduced visceral fat. 🧬 The key factor: Temperature and its diu…

1
“Heart on Fire? Timing Colchicine Right ⏳🧯🏥” 3:15

28d ago3:15

3:15

Colchicine 💊, once a humble gout remedy, is now reshaping coronary care 🫀. Trials show it reduces events in stable CAD ✅, but its benefit post-MI ⛑️ depends on timing ⏰. Inflammation matters — and so does when we strike. Colchicine in CAD: Small Pill, Big Debate 💊🔥🫀 An ancient anti-inflammatory has found new life in cardiology — reducing heart atta…

1
The Kilimanjaro Cure 🌋🥬:: 🧬: How Heritage Diets Heal 3:01

29d ago3:01

3:01

🌿 Switching to a Western diet 🍔 increased inflammation 🔥 and metabolic dysfunction. 🍌 Mbege and traditional foods calmed the immune system 🧘 and boosted IL-10 🕊️.By MasterMedFacts LLC

1
“Salted Truths: 🧂❤️⚖️ Rethinking Sodium for Heart and Kidney Health” 2:04

30d ago2:04

2:04

Not all salts are created equal! 🧂 Sodium chloride raises blood pressure and harms the heart 😈, while sodium bicarbonate may protect kidneys and improve outcomes in CKD/HF patients 🛡️🫀. Chloride channels (CLICs) play a hidden but vital role in heart health 🔌❤️. We need large RCTs 🧪📊 to guide smarter, personalized salt strategies for better cardiova…

1
💊 Oral Semaglutide Enters the Arena — The SOUL Trial 3:11

1M ago3:11

3:11

The SOUL trial 🧪 showed that oral semaglutide 💊 significantly reduced major cardiovascular events ❤️ (MACE) in people with type 2 diabetes 🩸 and ASCVD/CKD 🚑. Over ~4 years, it cut heart attacks 💥, lowered HbA1c 📉, reduced weight ⚖️, and inflammation 🔥 — all with a once-daily pill 🕊️ and no rise in serious side effects.…

1
Dr. RR Baliga’s Philosophical Discourses: Mozi (China, c. 470–391 BCE) – Founder of Mohism 3:48

1M ago3:48

3:48

Mozi, a prominent Chinese philosopher during the Warring States period, founded Mohism, a school of thought emphasizing universal love, meritocracy, anti-war principles, and consequentialist ethics. He advocated for frugality, social welfare, and pragmatic governance guided by Heaven’s will.By MasterMedFacts LLC

1
Coronary Artery Disease: Fix the Future, Not Just the Flow 🌍🫀🛠️” 2:14

1M ago2:14

2:14

The Lancet Commission calls for a shift from focusing on late-stage ischaemia to targeting early atherosclerosis (ACAD) 🫀🔍. By detecting and treating plaque early, we can prevent heart attacks, reduce deaths, and promote lifelong heart health 🌍❤️💡.By MasterMedFacts LLC

1
🧠💉 “Shots, Shingles, and Sharp Minds: The Brain-Boosting Power of a Vaccine 2:16

1M ago2:16

2:16

💉 A natural experiment in Wales showed that the shingles vaccine (Zostavax) reduced dementia risk by 20% over 7 years. 🧠 The study used a clever birthdate cutoff to mimic randomization and avoid confounding. 👩‍🔬 Women benefited more, suggesting immune or viral mechanisms beyond shingles prevention. 📊 Findings offer hope for low-cost, brain-protecti…

1
🚶‍♂️💉 Giant Strides with Weekly Semaglutide Jabs! 3:04

1M ago3:04

3:04

🚶‍♂️ The STRIDE trial tested semaglutide in patients with PAD and type 2 diabetes. 💉 Weekly injections for 52 weeks improved walking distance, pain-free mobility, and quality of life. 📊 Results showed significant gains vs placebo, with low adverse events. 🌟 Semaglutide may offer a new stride forward in treating functional limitations in PAD.…

1
Microbial Enzymes, Human Time: The Xenotopic Way to Live Longer 3:11

1M ago3:11

3:11

🧬 Xenotopic synthetic biology explores using enzymes from microbes (like bacteria and yeast) to reprogram human metabolism and delay aging. 🔋 These “borrowed” enzymes target amino acid levels, mitochondrial function, and redox balance to boost healthspan and fight age-related diseases. 🦠 From methioninase to NDI1 and AOX, these tools may turn micro…

1
🏃‍♂️💔 Heartbreak at the Finish Line: Racing Against Cardiac Arrest ⚡🚑 2:55

1M ago2:55

2:55

🏃‍♂️💔 In a study of 29 million race finishers (2010–2023), cardiac arrest rates during marathons and half-marathons stayed steady, but deaths dropped by half. 🧠⚡ Rapid CPR and AED use saved lives, with coronary artery disease—not hypertrophic cardiomyopathy—being the top culprit. 🫀🚑By MasterMedFacts LLC

1
🏃‍♂️🧠💡 Move. Spark. Remember: The Brain Boost of Exercise 2:16

1M ago2:16

2:16

🧠 Exercise is a powerful neuroprotective tool—it boosts memory, preserves brain volume, and reduces dementia risk. 💪 Through exerkines like BDNF and irisin, it sparks neurogenesis, clears inflammation, and enhances brain plasticity. 🌱 It also nurtures your gut microbiome and rewires your genes, making movement medicine for the mind.…

1
Dr. RR Baliga’s Philosophical Discourses: Socrates (Greece, 469–399 BCE) – Classical Philosopher 2:51

1M ago2:51

2:51

A brief overview of Socrates, the classical Greek philosopher widely regarded as the founder of Western philosophy. Known for his Socratic method of questioning, he profoundly influenced ethical thought, epistemology, and later philosophical traditions.By MasterMedFacts LLC

1
🎙️ “🥗 Plants, 🍽️ Plates, and 🤔 Paradoxes: Decoding Diets for a Long Life” 5:26

1M ago5:26

5:26

🍎 In this episode, we unpack a 30-year study on how diet influences aging. 🥗 AHEI, DASH, and Mediterranean diets boost your odds of healthy aging—by as much as 86%! ⚠️ But not all plant-based diets are equal: hPDI underwhelms, likely due to excluding protective animal foods like fish and dairy. 🚫 Ultra-processed foods, sugary drinks, and trans fats…

1
Hearts on the Line: Choosing Wisely, Saving Lives ❤️🫀 5:19

1M ago5:19

5:19

🫀 Heart transplantation is a life-saving treatment for end-stage heart failure, but donor hearts are scarce. 🔍 Donor selection is complex, involving factors like age, heart size, LV function, and comorbidities. 🌍 The U.S. is more conservative than Europe, with higher donor heart nonuse rates. ⚙️ New tools like Predicted Heart Mass (PHM), Organ Care…

Podcasts Worth a Listen

Docs In Orbit Podcasts

Podcasts Worth a Listen

Quick Reference Guide