This podcast delivers Dr. John Mandrola’s summary and perspective on top news of the week that cardiologists can’t miss. This podcast is intended for US health professionals only.
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The Bob Harrington Show is a podcast series of thoughtful interviews and discussions on topics at the core of cardiology and the practice of medicine.
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Welcome to "The AI Guys" podcast! Join hosts Lee Dickson and Rich Swier as they take you on a journey through the world of AI. In this episode, they share their personal journeys and experiences in the tech world. From discussing the parallels between the rise of the internet and AI, to exploring practical and technical aspects, Lee and Rich aim to make AI accessible and easy to understand for entrepreneurs, business owners, and the everyday consumer. With candid conversations and expert ins ...
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Join Medscape editor-in-chief Eric Topol, MD, and master storyteller and clinician Abraham Verghese, MD, as they interview experts on the hottest topics in healthcare ranging from COVID-19 to social determinants of health to bringing humanity back to medicine.
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AI and ECGs, novel ways to treat hypertension, combined lipid-lowering therapy after myocardial infarction, PFA and silent stroke, a move toward accountability in AF ablation, and pacing issues in TTVR are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial tr…
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AI for Freelancers: The Guide to Productivity and Profit
41:49
41:49
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41:49Are you ready to unlock your true potential as a freelancer? This episode dives into the revolutionary power of AI for independent professionals. We explore how AI is leveling the playing field, empowering individuals to achieve productivity and scale once reserved for large corporations. From automating tedious tasks to mastering client communicat…
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The FAME 3 trial 5-year results, TAVR at 5 years, pacers after TAVR, and mavacamten not a wonder drug are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I FAME 3 at Five Years Stents as Good a…
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AI vs. SaaS: The Future of Software Development
41:34
41:34
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41:34How is AI poised to revolutionize the software industry? In this episode, we explore AI’s potential to disrupt traditional SaaS models and reshape how applications are built and used. Diving into the concept of an "AI-first" mentality in software development, discussing how it could empower entrepreneurs, streamline workflows, and create more intui…
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April 11, 2025 This Week in Cardiology Podcast
27:31
27:31
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27:31The TAP-IT, STRIDE, FreshUP, and SINGLE SHOT CHAMPION trials are discussed by John Mandrola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I TAP IT TAP IT trial https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.124.073521 …
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For America First, Invest in Science and the NIH
29:33
29:33
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29:33A panel discussion of a Presidential Advisory from the American Heart Association that outlines the importance of funding for scientific research and the need for a robust National Institutes of Health. This podcast is intended for healthcare professionals only. To read a transcript or to comment, visit https://www.medscape.com/author/bob-harringto…
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The Future of Medicine: AI-Powered Healthcare Solutions
45:18
45:18
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45:18Is AI the key to a healthier future? In this episode, we explore the transformative potential of AI in the healthcare industry. Ben Scharfe, joins us to discuss how AI is being leveraged to improve patient care, streamline clinician workflows, and revolutionize healthcare systems. We look into the challenges of AI adoption in healthcare, including …
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Trials from the 2025 American College of Cardiology scientific sessions, including the WARRIOR, PROTECT TAVI, DAPATAVI, and SOUL are reviewed by John Mandrola, MD This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I Thank you Comments II WARRIOR Women’s Ischem…
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AI in Vegas: Hope or Hype? A Reality Check from HumanX
20:41
20:41
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20:41What were the real takeaways from the HumanX AI conference in Las Vegas? In this quick-hit episode, Rich shares his firsthand experience at the inaugural event. Offering a candid critique of the conference format and content, highlighting the hyper-focus on security and AI-powered development while noting a lack of truly groundbreaking insights. Ri…
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Stopping oral anticoagulation after AF ablation, the core problem with paradoxes like the smoker’s paradox, chronic total occlusion PCI, and an ACC/EHRA preview are discussed by John Mandrola, MD, in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medsca…
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AI Security: Building a Gold Standard for Your Organization
26:43
26:43
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26:43How secure is your AI? In this episode, we dive into the critical aspects of AI security and compliance, exploring the fundamental shift in security thinking required when integrating AI agents into your business. Discussing the transition from traditional "castle" security to a "hotel" model, emphasizing the need for granular access control and st…
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A large trial in cardiac pacing finally published, PVCs and cardiomyopathy, cannabis, CV risk and the danger of observational studies, and the tale of two disparate statin trials are the topics John Mandrola, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment,…
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Is SaaS Dead? The Rise of AI-First Software Development
33:24
33:24
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33:24Is SaaS dead? The era of traditional SaaS is being redefined by AI. In this episode, we explore the transformative impact of AI on the software industry and discuss the future of SaaS in an AI-first world. We dive into the potential for AI to revolutionize app development, disrupt traditional business models, and empower entrepreneurs with groundbr…
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Listener feedback, resistant hypertension, K-binders for MRA use in heart failure, nutritional epidemiology, and a positive study for vitamin D are the topics John Mandrola, MD, discusses in this week's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/tw…
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AI's Next Chapter: Grok 3, OpenAI, and the Path Forward
26:57
26:57
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26:57The AI world is abuzz with exciting new developments! In this episode, we discuss the latest AI news, including the groundbreaking Grok 3 release from XAI. We explore its potential impact on the AI landscape, the shift towards inference-based models, and the implications for companies like Google, Microsoft, and OpenAI. Join us as we analyze the ex…
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Listener feedback on asymptomatic aortic stenosis (AS), transcatheter aortic valve replacement (TAVR) vs surgical aortic valve replacement (SAVR), coronary artery calcium (CAC), and revascularization for patients with ischemic LV dysfunction are discussed by John Mandrola, MD, in today's podcast. This podcast is intended for healthcare professional…
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Top 4 AI Agents to Boost Your Business Profits
29:59
29:59
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29:59Want to unlock the power of AI to supercharge your business profits? In this episode, we explore the top 4 AI agents that can revolutionize your sales, customer support, and marketing efforts. Discover how these intelligent agents can automate tasks, improve efficiency, and drive revenue growth. We'll delve into the specific use cases for each agen…
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The treatment of asymptomatic aortic stenosis, the move to composite endpoints in trials, IFR vs FFR and high-frequency low tidal volume ventilation for AF ablation are the topics John Mandrola, MD, discusses in today's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://ww…
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The Future of Web Browsing: AI Agents and Automation
22:05
22:05
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22:05Ever wondered how AI is changing the way we browse the web? In this episode, we explore OpenAI's latest release, Operator, an AI agent that can surf the web and perform tasks on your behalf. We'll discuss its capabilities, potential use cases, and how businesses can leverage it to automate tasks, conduct research, and improve efficiency. Discover h…
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Blanking period after AF ablation, periprocedural MI after PCI in non-STEMI, predicting AF after ischemic stroke, and the proper standards for mitral valve repair in primary mitral regurgitation are the topics John Mandrola, MD, discusses in today’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or…
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Ever wondered if AI models really matter? In this episode, we explore the evolving landscape of AI models, discussing their commoditization, specialization, and the growing importance of reasoning and inference. We'll delve into the differences between various models, such as OpenAI's GPT-3 and DeepSeek, and how they are being used to power a wide …
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Silent cerebral embolism after LAAC, AI in ECG rhythm analysis, anti-thrombotic strategies in patients with AF and CAD, and subclinical AF are the topics John Mandrola, MD, covers in today’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Silent…
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Ever wondered how AI is disrupting the events and media industry? In this episode, we explore the transformative impact of AI with Heather Holst-Knudsen, President & CEO of H2K Labs and host of the upcoming Revved Up conference. Discover how AI is reshaping content creation, audience engagement, and revenue generation in the information and data ec…
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Sugar-sweetened beverages, the epidemiology of driving after an ICD, BP measurements, and massive EBM lesson in EVT for acute stroke are the topics John Mandrola, MD, discusses in today's podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Sugar-Swe…
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Revving Up with AI: Transforming Auto Dealerships
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32:32How is AI transforming the auto dealership industry? In this episode, we explore the ways AI can revolutionize sales, enhance service department efficiency, and improve customer experiences. We'll discuss the challenges dealerships face, such as speed to lead and personalized communication, and how AI can provide solutions. Discover how AI is drivi…
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Another negative AF ablation trial, predicting AF after stroke, the value of RCTs, troponin testing in the ED and surgical aortic valve choice are the topics John Mandrola, MD, discusses this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I AF ablati…
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Cardiology 2024 Highlights and Predictions for 2025
36:09
36:09
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36:09Drs Harrington and Gibson review their picks for the top cardiology trials of 2024 and look ahead to 2025, particularly what health topics may be prioritized by the new administration. This podcast is intended for healthcare professionals only. To read a transcript or to comment https://www.medscape.com/author/bob-harrington Beta-Blockers after Myo…
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Beyond Saving Money: How AI Can Transform Customer Support
42:20
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42:20Ever wondered how to save money while effectively using AI in customer support? In this episode, we discuss the challenges and opportunities of AI in customer support with Wayne Butterfield, a consultant for ISG. Discover how to leverage AI to improve customer experiences, enhance knowledge management, and optimize support workflows. We also explor…
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Familial hypercholesterolemia, cardiac arrest therapy, Factor XI inhibition, and tricuspid valve interventions are the topics John Mandroa, MD, discusses in this week’s podcast. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Familial hypercholesterolemi…
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Ever wondered what's next for AI in 2025? In this episode, we explore the future of large language models (LLMs), the role of synthetic data, and the evolving strategies of major players like OpenAI, Google, and X (formerly Twitter). We'll discuss the challenges of data scarcity, the increasing importance of inference, and the potential impact of A…
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Renal denervation, the obesity paradox, JACC and the FINEARTS trial of finerenone in HFpEF, a setback for a PFA system, and coffee are the topics Jon Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. RDN CMS https://www.cms.…
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The Future of Art: How AI is Democratizing Creativity
33:10
33:10
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33:10Ever wondered how AI is revolutionizing image generation and its impact on creative industries? In this episode, we explore the exciting world of AI image generation with Jeff Hazelton, a digital art veteran and founder of BioLucid. Discover how AI is transforming the way artists and businesses create and utilize images, from generating immersive v…
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Alcohol and cancer, GLP-1 trial representativeness, diagnosing CAD, changing stroke rates in patients with AF, blanking periods after AF ablation are the topics John Mandrola, MD, covers this week. This podcast is intended for healthcare professionals only. To read a partial transcript or to comment, visit: https://www.medscape.com/twic I. Surgeon …
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