Oracle Life Sciences Vice President of Global Innovation, Kathy Vandebelt, interviews industry experts and leaders on pressing topics in the Life Sciences industry.
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Dr. Karen Wolfe is an Australian physician with a mission. She is the leading voice to discern how to use the massive amounts information in the field of nutrition, mind/body medicine and functional medicine. Dr Karen will offer you strategies and plans to take your health to the next level. With scientifically sound principles, she will offer tips, motivation and inspiration to support your total health and wellness.Learn more about her work at http://drkarenwolfe.org/
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Ep. 43: Running regulatory and clinical operations in an AI world
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41:27Artificially intelligent tools are revolutionizing nearly every stage of the drug discovery process, offering substantial potential to reshape the speed and economics of the industry. As the drug discovery and preclinical stages speed up and potentially produce more drugs to test in the clinical trial phase, how do clinical researchers prepare and …
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Ep. 42: Creating drugs at the speed of AI
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27:39Artificial intelligence (AI) is one of the most discussed technologies across all industries. Life science professionals working in the pharmaceutical industry strive to improve people’s lives tackling incredibly complex diseases. Drug development is often perceived as slow. As the pharma industry looks to improve the drug development process AI pr…
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Ep. 41: CancerX: Reducing incidence, burden, and disparities in cancer care
50:11
50:11
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50:11Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020. President Biden has reignited the Cancer Moonshot initiative and set a new national goal: “if we work together, we can cut the death rate from cancer by at least 50% over the next 25 years and improve the experience of people and their families living wit…
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Social Media Risks for Children and Adolescents
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14:59Social media can pose a profound risk of harm for children’s mental health and development. Excessive use and harmful content exposure is part of the Surgeon General’s public health advisory on Social Media and Youth Mental Health. Listen to this podcast and share it to keep the conversation going !By Dr. Karen Wolfe
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Ep. 40: CancerX: Breaking down the barriers to digital innovation use in oncology
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30:52
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30:52The US cancer death rate has fallen by 33% since 1991 with an estimated 3.8 million deaths averted. This is attributed to “good progress” improvements in cancer treatment, decreases in smoking, and increases in early detection. A recent rise in advanced cancer cases reported is believed to be an outcome of the COVID-19 pandemic which delayed screen…
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Ep. 39: Recruiting and retaining experienced principal investigators
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39:55The success or failure of clinical trials is dependent in large part on the engagement of the principal investigator (PI). PIs play an important role in trial selection, site activation, and study execution. This includes but is not limited to, the development and implementation of a strategy to maximize enrollment, optimize data quality, and ensur…
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Ep. 38: Psychological aspects of clinical trials
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32:13
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32:13Researchers use controls to help them understand what effect a new therapy or drug might have on a particular condition. Clinical research practice favors placebo controls over usual-care controls. Sometimes a person can have a response, positive or negative, to the placebo control. These responses are known as the "placebo effect and nocebo effect…
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Ep. 37: Digital transformation: empowering or encumbering for research sites?
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42:46
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42:46Clinical research professionals across all types of research organizations often struggled with implementing process improvements and the adoption of digital tools. When external factors (such as pandemic disruptions) force transformational process changes, the adoption of digital tools follows. At that point, the value of the new solutions suddenl…
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Ep. 36: Digital predictions for clinical research in 2023
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33:31Clinical research can make all the difference when it comes to saving people’s lives or improving their quality of life. In this episode, Mathias Eichler-Mertens, Managing Director of Accenture Life Sciences R&D Europe, and Henry McNamara SVP and GM of Oracle Health Sciences, will discuss what can be done to boost innovation and productivity in the…
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Ep. 35: Converting to a patient-centric care model
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51:00The digital health ecosystem has helped create an infrastructure that supports the transformation of the organization-centered care model into a patient-centered care model. Various reports highlight the staggering investments and the market growth in digital health technologies supporting this change. In this episode of the Latest Dose, Naomi Frie…
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Monitoring safety of biological products, drugs, and devices in healthcare is a priority for inventors, prescribers, regulatory authorities and of course patients. Safety data are collected and analyzed throughout product development and assessed prior to approval for commercial use. In this episode, Dr. Joseph (Joe) Tonning medical and pharmaceuti…
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"First, do no harm" is a popular saying amongst those involved in the healthcare, medicine, or bioethics field, and is a basic principle taught in health-related courses. To faithfully follow this principle, a health professional should help their patients by recommending tests or treatments for which the potential benefits outweigh the risks of ha…
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Ep. 32: Expanding our knowledge by embracing real-world evidence
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44:29
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44:29On receiving news of a health concern there is an immediate thirst for knowledge to understand the condition, the care, and treatment options available. As a healthcare professional assesses the health status of a person, it may be decided that prescribing a therapeutic drug is the best course of action. These treatments are assigned systematically…
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Ep. 31: Advancing patient informed consent
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36:56Patients are the most important constituent in clinical development and provide the necessary information to assess the safety and efficacy of new medicines. Participation in clinical research requires informed consent. The importance of informed consent cannot be overstated – participants must completely understand all that is involved in a clinic…
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Intentional Living - How to Be Fully Present with Life
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9:14On this episode of The Dr Karen Health Show, I share my personal commitment to being more fully present in the moment - in my relationships, down time, walking and eating. It’s a great practice !By Dr. Karen Wolfe
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Ep. 30: Collaborating to scale the use of health sensor data
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41:19
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41:19Access to relevant and trustworthy data to make accurate and timely healthcare decisions is critical. Cohesive industry collaboration is key to removing barriers to data access and increasing adoption of sensors in health science. In this episode, Jennifer Goldsack, Chief Executive Officer of non-profit Digital Medicine Society (DiMe) discusses a m…
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Ep. 29: Debunking the myths of clinical trials; leveraging the realities
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38:02Clinical research is the study of health and illness in people. It’s about putting people – the participants and volunteers – at the center of finding out if a new treatment is safe and effective. What clinical research and clinical research participation means is often discussed and frequently shared. In this episode, Ken Getz, Executive Director …
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Ep. 28: Celebrating clinical trial volunteers
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26:05International Clinical Trials Day, celebrated each year on May 20th, commemorates the day that James Lind began the first randomized clinical trial in 1747. It also provides an opportunity to recognize and thank everyone involved in clinical research. In this episode, Bruce Hellman, Co-founder and Chief Patient Officer at uMotif offers a practical …
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Ep. 27: Using RWE to deliver better treatments for patients
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42:36The use of mobile devices, social media, wearables, and other biosensors continues to expand year on year. The curation and analyses of health-related data is accelerating, and these data provide the potential to answer questions previously thought infeasible. When a researcher is seeking answers to a health question, when is it appropriate to use …
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There is so much you can do to protect your brain even if you have the Alzheimer’s Gene variant. Learn all about it in this episode of The Dr Karen Health ShowBy Dr. Karen Wolfe
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Ep. 26: Facilitate clinical research in Europe
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46:23
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46:23The European Union (EU) has been on a path to harmonize the clinical trial process and requirements since 2004 starting with the Directive. The next step came 10 years later, in 2014, with the Clinical Trial Regulation (CTR). This year, as of January 31, the Clinical Trials Information System (CTIS) went live and supports the flow of information be…
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Nutrigenomic testing offers a roadmap for a personalized wellness plan based on your unique genetic variations. I can customize your health plan based on results and can support metabolic and mental health, athletic performance and weight and diet personalization. This episode of The Dr Karen Health Show explains what it is and how it works…
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Over the past several days, the situation in Ukraine 🇺🇦 has escalated into war and many of us are feeling anxious, sad, fearful and angry. In this special episode of The Dr Karen Health Show, I share what I am doing to build mental resilience in these times of stress.By Dr. Karen Wolfe
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Ep. 25: Raising awareness for unknown illnesses
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37:49
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37:49There are more than seven thousand rare diseases in the world – 95% of which have no known treatment. The term rare diseases is a cruel misnomer – in fact they aren’t that rare, and importantly, the definition of what constitutes a rare disease differs by country. To raise awareness, Rare Disease Day is recognized on the last day of February annual…
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This episode of The Dr Karen Health Show reviews the bio markers you need to keep track of for your heart ❤️ health. Be sure to have a pen and paper to write these down !By Dr. Karen Wolfe
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Part 2 of The Dr Karen Health Show Podcast series in The Mind/Heart Connection reviews Dr Karen’s 4 “M’s” of building resilience and positive psychological health. Can you guess what they are?By Dr. Karen Wolfe
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Does our mental health affect our heart ?A large growing body of evidence shows mental health affects the heart directly. These are direct effects through biological pathways as well as indirectly through lifestyle factors. This podcast will change the way you view the head / heart connection ❤️By Dr. Karen Wolfe
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Ep. 24: Reimagining clinical research as new capabilities come to market
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46:01
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46:01Life sciences organizations face intense pressure to speed clinical trials while boosting operational efficiencies to battle the rising costs of drug development. So what does the future of clinical trials look like? In this episode, Dr. Avi Kulkarni, senior vice president of research and development at Cognizant, and Henry McNamara, senior vice pr…
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Ep. 23: Finding strength in hardship – the story of Joey’s Little Angels
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34:00When Nicole and James Angiolino’s son Joey was diagnosed with the rare disease Hurler’s Syndrome at seven months old, they did everything they could to save his life. They left their eldest son Nicholas, their family, friends, and teaching careers behind and headed to Duke University Hospital in North Carolina to get him the care he needed. James a…
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It is never too early to encourage healthy eating in our children. In this episode of The Dr Karen Health Show Podcast, Dr Karen shares great fun tips to get children involved and excited about making fun and healthy treats !By Dr. Karen Wolfe
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Ep. 22: Setting healthy boundaries for optimal health
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42:49
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42:49Anxiety, stress, and exhaustion are on the rise and impacting many of us. With a lot happening in our world that we don’t have much control over, our routines have been disrupted and it’s affecting our overall health and mindset. Combine that with the stress holidays can bring, and you have a recipe for total burnout. In episode 22, we wanted to co…
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The scariest thing about Halloween is the sugar! As a Sugar Buster Coach, you can imagine how scary Halloween is for me. In this episode of The Dr Karen Health Show, I discuss ways to make this holiday season even healthier than ever !By Dr. Karen Wolfe
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Ep. 21: Changing the face of men’s health - “the mission behind the moustache”
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31:27
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31:27Men across the globe are dying too young. In the US, three out of four suicides are men, and one in eight (around 10.8 million) will be diagnosed with prostate cancer and testicular cancer, the most common cancers in young men. Our fathers, partners, brothers, and friends are facing a health crisis that isn’t being talked about, and it’s time to sp…
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Nutrigenomics is a wonderful way to drive behavior motivation and change your life! In this Podcast Dr Karen discusses how she has used Nutrigenomics to shift lifestyle habits in powerful waysBy Dr. Karen Wolfe
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Ep. 20: Collaborating with patients throughout drug development
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43:02There’s no question that clinical research is the backbone of healthcare invention, helping to improve the prevention, detection, diagnosis, and treatment of disease. But at the heart of it all you’ll find that patients are the true lifeblood of clinical research, keeping things moving and allowing researchers to save more lives every day. With pat…
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Ep. 19, Part 2: Advancing patient health through medical devices
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21:33
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21:33Medical devices are an integral part to many procedures and treatments, and last month we started to investigate the vast and innovative world of these types of technologies in a two-part series on The Latest Dose. In part one, our esteemed guests, Dr. Khaudeja Bano, the executive medical director of combination product safety, global patient safet…
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If ever there was a time to build mental strength — it is NOW. In the episode of The Dr Karen Health Show, Dr Karen brings the 4 habits to build mental strength shared by Jay Shetty, author of “Think Like A Monk”By Dr. Karen Wolfe
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This Dr Karen Wolfe Health Show episode explains the comprehensive 7 day medical detoxification program I just returned from. Sanoviv is a cutting edge facility focused on whole-body healing.By Dr. Karen Wolfe
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Ep. 18, Part 1: Advancing patient health through medical devices
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40:16
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40:16From bandaging a sprained ankle and diagnosing HIV/AIDS, to implanting an artificial hip and monitoring your heart, medical devices are an integral part to many medical procedures and treatments. There is a lot to unpack when it comes to medical devices, so we’ve invited industry leaders Dr. Khaudeja Bano, the executive medical director of combinat…
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Left untreated, acid reflux (heartburn), can result in many chronic digestive issues. In this episode of The Dr Karen Health Show, Dr Karen Wolfe talks about lifestyle and dietary changes that can help!By Dr. Karen Wolfe
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There has been a huge shift in understanding the link between mouth health and body health. Dr Karen Wolfe answers two questions - How can the health of our mouth affect our body ?Why are the simple habits of daily brushing and flossing more important than we might think?By Dr. Karen Wolfe
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Ep. 17: Renovating ICH guidelines to support the evolution of clinical research
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41:59The clinical research ecosystem has undergone an evolution over the past 18 months, and many want it to continue. To help set the industry on a solid path forward, ICH has created guidelines that provide direction on behaviors and actions to take. Recently, a specific set of these guidelines, ICH E6 Revision 3 and E8 Revision 1, have been referred …
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Can you guess what the four bad for the bones foods are ? In this podcast episode. Dr Karen Wolfe shares valuable insights in ways to support healthy bonesBy Dr. Karen Wolfe
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A common question wellness seekers ask is about how to read a food label. In this podcast episode Dr Karen Wolfe breaks down the important features to pay attention to in a label before you choose to buy it. She also gives examples of foods and their labelsBy Dr. Karen Wolfe
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In this Podcast Episode I read a passage from “The Book of Awakening” by poet and spiritual teacher, Mark Nepo. Life is fragile and unbreakable at the same time and wonder helps us find the indestructible part of the thread.By Dr. Karen Wolfe
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Do you know the major causes of vision loss? Did you know most of these causes, if caught early, can be prevented?Do you know how to protect your eyes from the sun and computers and harsh environmental exposure? Listen to my podcast if you appreciate the gift of your vision!By Dr. Karen Wolfe
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Ep. 16: Clinical Trials Day – Thanking those that make clinical research possible
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22:44
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22:44Aboard the HMS Salisbury of Britain’s Royal Navy on May 20th, 1747, surgeon James Lind performed what is often considered to be the first randomized clinical trial. Now, every May 20th, International Clinical Trials Day gives us a well-deserved occasion to honor and thank both the professionals and patients who make clinical research possible. It a…
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Do you want to improve your mood and metabolism, have more energy and feel great? Todays podcast episode talks about the most efficient way to have all this! What do you think it is ? HINT - It is RHABy Dr. Karen Wolfe
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So many of us have sugar cravings that can feel uncontrollable! In this podcast I share that it is not about willpower.. it’s about biochemistry. You can change your internal pharmacy with lifestyle shifts. This episode is about action and relief !By Dr. Karen Wolfe
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Ep. 15: Embracing Telemedicine Now and in the Future
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42:17
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42:17As a methodology that’s generally been underutilized in the past, the pandemic has brought telemedicine to the forefront as a way for doctors to care for their patients, without them having to come into an office or site. But how exactly is it being used in medicine and clinical research today, and will it still be widely used after the pandemic en…
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