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This Week in Startups

Jason Calacanis

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Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
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Product Hunt Radio

Product Hunt

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Product Hunt Radio is a a weekly podcast with the people creating and exploring the future. Tune in every week with Ryan Hoover and Abadesi Osunsade as they're joined by founders, investors, journalists, and makers to discuss the latest in tech.
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Product Hunt

Product Hunt

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Product Hunt Radio (PHR) is for the product geeks. Each week Ryan Hoover and Erik Torenberg are joined by founders, investors, and product people in the startup community & beyond to chat about products, technology, and the people who make them. Join us and visit Product Hunt (http://producthunt.com) to find the best new products, every day.
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A weekly podcast hosted by Trevor Lohrbeer, a productivity expert and co-founder of Day Optimizer, and an artificial intelligence. Each week we discuss topics related to productivity and AI. All conversations are recorded live using ChatGPT voice mode or equivalent. Nothing is pre-scripted.
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Welcome to Entrepreneur Talks by STATION F, a podcast to inspire and support entrepreneurs in their journey! STATION F is the world's largest startup campus, with 1000+ startups working on-site. Located in Paris, STATION F gathers all the services an entrepreneur might need under one roof, including 350+ VC funds, 30+ public administrations, and mentorship offices by leading tech companies like Apple, Google, AWS, and OVH. We are here to help bring ambitious ideas to life and, in this podcas ...
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Hear experienced aviation and aerospace professionals share their perspective, pathways, and expertise on how to productively navigate your aviation and aerospace aspirations. Enjoy an eye-opening, engaging discussions in a casual-conversation type of environment covering a plethora of options, opportunities, and possibilities in the aviation and aerospace industries. All Things Aviation & Aerospace is hosted and moderated by Vince Mickens, the Founder & CEO of Private Air Media. His extensi ...
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The Bobcast

Bob Cahill

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Bob Cahill launched The Bobcast in December 2013 with his first guest, the enigmatic Didgeridrew, and quickly became known for his captivating conversations with a wide range of influential figures. Over the years, The Bobcast has featured countless musicians, artists, actors, and religious figures, solidifying its place in the diverse podcast landscape. Guests on the show have included notable names like Big Data, Dispatch, Schoolly D, Daru Jones, and Landall Goolsby from Marvel’s Agents of ...
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Today’s show: It’s another All Star Investor Panel! Jason and Alex welcome TrustFund VC founder Sophia Amoruso AND WeekendFund investor/Product Hunt founder Ryan Hoover.Together they’re going DEEP on the current environment for startups, founders, and investors. How do tell durable from brittle revenue… Everyone’s different approaches to follow-on …
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Today’s show: Alex is back with three more awesome interviews with founders on the bleeding edge of innovative tech. Dr. Hon Weng Chong walks us through the basics of biological computing and Cortical Labs’ first-ever commercial computer running on living human cells. Turing founder Jonathan Siddarth unpacks the secrets of LLM benchmarking, and exp…
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Pastor Ryan has the entire church help him preach an illustrated message. You'll understand as you listen. But the simple question is being asked; Is Jesus Enough? For most of us, we'd immediately say "Yes." But our lives show a different answer. Today is about connecting our Faith with our Reality & leaning on the Jesus who is always enough.…
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Today’s show: SYDNEY SWEENEY’S AMERICAN EAGLE AD DIVIDES OUR PANEL!PLUS WHAT STARTUPS CAN LEARN FROM THE VIRAL ASTRONOMER RESPONSEJason, Alex, and Lon are looking at some of the biggest media stories of the day before returning to their favorite topic, tech. Tune in for deep dives on IMAX’s new AI film festival, Figma’s big IPO and much more! * Tim…
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Today’s show: Jason’s back and filling us in on his experiences in Washington DC, at the All-In AI Summit, including getting a Trump shoutout from stage, debating immigration with VP Vance, and calling out Sec. Wright for dismissing solar power.THEN Jason and Alex talk about the immense promise of open-source robotics and check out Hugging Face’s R…
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Today’s show: TWiST is back with a three more hugely insightful (and also fun!) founder interviews. First up, Trey Holterman from Tennr tells us why getting in to see a specialist is so time consuming, and how AI is making the entire health care industry more streamlined.THEN Gill Verdon from Extropic AI unpacks deterministic vs. probabilistic comp…
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Today’s show: TWiST is back with a trio of can’t miss interviews with some of our favorite TWiST 500 founders. First up, John Harris of Harbinger Motors tells us about making his EV batteries right here in the USA, and why the loss of EV tax credits might not hurt the business as much as you’d think… THEN, we’re talking to James Hawkins of PostHog …
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Today’s show: WHY DOES @SUBSTACKINC NEED $100M IN NEW FUNDING?HOW DO THEY PLAN TO STAY AHEAD OF @BEEHIIV?Jason and Alex are debating the future of indie publishing on an all-new TWiST, considering the future of these rival platforms, plus Patreon and more.PLUS they’re digging into Lovable’s latest raise and what it says about the current economics …
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Today’s show: Jason and Alex tackle a full tech and business news docket on today’s show, including Jason’s big SF trip with Launch Accelerator’s 34th cohort, some peculiar social media posts from VC Geoff Lewis, a look inside the HUGE seed rounds being commanded by early-stage AI startups, crunching the numbers on how much compute data centers nee…
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Ben Jones, President and CEO of the Ruffed Grouse Society and the American Woodcock Society, joins Reid in a discussion about the great work being done on the ground at RGS, and the work that still needs attention. The duo digs into the work of listening to and coalescing the wants and needs of different groups to the ultimate good of grouse, woodc…
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Today’s show: On today’s show… Jason and Alex are considering the fallout of Windsurf’s OpenAI deal, the company’s latest agreements with both Google and Cognition AI, and how “blitzhiring” is actually playing out in real-world startups.Plus Jason’s short- and medium-term predictions for AI’s impact on the job market, Tesla’s latest expansion of it…
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Today’s show: Grok 4 just leapfrogged OpenAI to become the top AI model—and it’s not just hype. In this episode, @Jason and @alex break down Grok’s AGI-level performance, the massive drop in LLM pricing, and why some companies are raising prices anyway. They also dive into the Missouri AG’s investigation into AI “bias,” the future of First Amendmen…
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In this episode of AI Basics, Jason sits down with Yoav Shoham — Stanford professor emeritus and co-founder of AI21 Labs, creators of Jurassic-2, Wordtune, and the new orchestration system Maestro. They unpack: Why enterprise AI struggles with reliability What orchestration really means (and why LLMs alone aren't enough) The pitfalls of “agent-wash…
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On a brand new TWiST, Jason and Alex ponder… What if every Tesla doubled as a Starlink-powered Wi-Fi hotspot? Plus, Nvidia’s historic $4T valuation, Perplexity’s fancy new AI browser that literally books flights, Linda Yaccarino steps down as X CEO, Waymo launches teen accounts, and maybe recording everything all the time has some disadvantages? La…
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Today’s show: Cloud seeding startup Rainmaker faced a viral backlash after deadly floods in Texas—so @Jason hosted an emergency X Spaces with founder Augustus Doricko to unpack what really happened. Did Rainmaker cause the floods? How much water can cloud seeding actually produce? Is it safe, and should we even be doing it? They dive into the scien…
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Today’s show: Startup exits are heating up with $67.7B in Q2 activity, QSBS just got a major expansion, and Robinhood is pushing boundaries with tokenized SPVs. In this episode, @Jason and @alex break down what it all means for founders and investors, plus the rise of Elon’s “America Party,” TikTok’s potential reboot, and why SaaS startups must reb…
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Today’s show: It’s another blockbuster panel of insiders, as Alex sits down with Astasia Myers from Felicis, Matt Turck from First Mark Capital, and D.A. Wallach of Time BioVentures. AI is reshaping early-stage investing, with startups raising record-setting rounds adn chasing $100B+ markets. Meanwhile, biotech faces a “Great Depression” as public …
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Today’s show: Grammarly is acquiring the beloved email app Superhuman! In today’s extremely timely episode, @alex sits down with Grammarly CEO Shishir Mehrotra and Superhuman founder Rahul Vohra to unpack why they’re merging, how they plan to combine apps and AI agents, and what it means for the future of email and work. PLUS they reveal how Gramma…
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Today’s show: Jason sits down with Balaji Srinivasan in Singapore to explore how he's turning years of theory into reality with Network School—the first node of a broader vision for internet-native, decentralized societies. Balaji explains how these “sharp societies” combine education, co-living, and startup culture to create physical communities a…
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Zander Ault of Patagonia, AZ joins Reid to discuss what it’s like to live and build a business in one of bird hunting’s most iconic destinations. Not a hunter himself, Zander (and his partner Heidi) landed in Patagonia for the extraordinary gravel cycling, but soon found that the region was ground zero for desert quail hunters. Having opened and ow…
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Today’s show: EVs are igniting a global tariff war, and Xiaomi’s shockingly cheap, high-quality electric cars threaten to obliterate Western automakers, sparking fears of a manufacturing wipeout. In today’s brand-new TWiST, Jason and Alex dive into the EV price war, Uber’s rumored plan to team up with Travis Kalanick on a self-driving takeover, and…
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In this episode, Jason dives deep into the future of multi-agent systems with Saurabh Tiwary, VP & GM of Cloud AI at Google. They explore how teams of AI agents—not just single models—can collaborate to solve complex problems, helping startups scale faster with fewer resources. Saurabh introduces Google Cloud’s open frameworks: Agent Development Ki…
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Today’s show: In this powerhouse VC roundtable, @Jason sits down with Sequoia’s Doug Leone and Cyberstarts’ Gili Raanan to share brutally honest insights on startup recruiting, evaluating second-time founders, and how to truly find product-market fit. They break down why big-tech résumés can be misleading, how to structure early teams, and what sep…
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Today’s show: Tesla’s robotaxi launch, AI producers, job destruction, and smart toilets? In this episode of This Week in Startups, @Jason and @alex break down Tesla’s cautious rollout strategy, how AI is quietly replacing producers and employees, why second-movers like Tesla and Ramp often win, and how Throne Science is turning gut health into a bi…
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Ryan Yang is the founder and CEO of Tryangle Construction, Inc., a leading residential remodeling and renovation firm based in Southern California. With a commitment to quality craftsmanship and transparent communication, Ryan has grown Tryangle into a trusted construction partner for homeowners, realtors, and real estate investors. His leadership …
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Applauded as a seasoned marketer who focuses on what matters for companies: their brand, strategy, growth, and ultimately ROI, Angelo Ponzi has been a valuable asset to various businesses on a global and national scale. Angelo's experience spans from start-ups to mature companies and their services and products in all stages of their lifecycle, fro…
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Today’s show: AI has been feasting on the open web—but is the free lunch over? In this explosive episode, @Jason and @alex call out OpenAI and others for “strip mining” the internet’s content without paying creators. As lawsuits pile up and new defenses like AI-robots.txt emerge, a reckoning looms. Will AI be forced to pay for its training data? Di…
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Dr. Cynthia West is the Director of the Leatherby Center for Entrepreneurship and Business Ethics, and Clinical Associate Professor at Chapman University. After spending 30 years as a sales and marketing leader for tech startups, she returns to her roots in academia. As Director, in just one year, Dr. West has re-invigorated the Center by raising o…
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In this episode, we visit Orvis Hill Country Shooting Grounds in Blue Ridge Summit, PA, where General Manager Jeremy Mays is joined by new property owner and tech entrepreneur Ben Wallace. While Orvis continues to manage day-to-day operations, Ben brings fresh investment and bold ideas to elevate the facility. Together, they share their vision, rec…
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Today’s show: In this episode, @Jason and @alex explore how AI is reshaping the economy—from Pano AI’s $44M raise to fight wildfires with drones, to Amazon CEO Andy Jassy’s memo foreshadowing white-collar job cuts, to Meta’s stealth move poaching Scale AI talent. They dig into the collapse of early-career roles, the slow disappearance of the gig ec…
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Today’s show: Meta just took a 49% stake in Scale AI, and the shockwaves are hitting the entire AI ecosystem. In this episode, @Jason and @alex unpack the deal’s implications: Google ($150M customer!) and others are fleeing Scale, worried Meta will hoard its RLHF infrastructure and cut off competitors. Startups like Labelbox, Turing, and Handshake …
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Brandon Hoover is a multiple presidents club-winning medical sales rep who worked in various sectors including orthopedics at Stryker and Oncology Diagnostics with Caris Life Sciences. He noticed there was a gap in the information provided to medical sales reps and decided to create a platform to help close more deals in a saturated and rapidly cha…
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Bringing back a favorite episode from 2019, Reid digs deep into shot-shell development with two members of the Winchester Ammunition Team-- Mike Stock and Ben Frank. This episode explores all facets of shotgun shells including performance, construction, and the different materials that impact both. It's a great chance to "nerd out" on the nuances o…
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Today’s show: In this episode of This Week in Startups, @Jason and @Alex break down Stripe’s big bet on crypto wallets with its latest acquisition of Privy, the return of major M&A activity from Meta, DoorDash, and Stripe, and the rapid rise of robotics replacing soul-crushing warehouse jobs. They dive into why today’s toy-like robot arms will beco…
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Today’s show: Alex moderates a TWIST VC Roundtable with Jason, Paige Doherty (Behind Genius), and Altimeter’s Megan Reynolds about the state of early-stage venture capital. They break down the rise of secondary markets as a key liquidity path for VCs, analyze the resurgence in M&A activity from major players like Meta, Databricks, and OpenAI, and q…
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Today’s show: Jason and Alex dive into why Y Combinator startups are raising at sky-high valuations with relatively low ARR—what does that mean for investors and founders? VC funds are slowing down and returning to pre-ZIRP pacing, signaling a reset in the market. Plus, in this week’s Office Hours, Sean Steigerwald, founder of CustomerIQ, demos his…
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Today’s show: Jason and Alex dicuss stories shaping the tech and startup world: Circle’s explosive IPO and what it signals about crypto regulation and public market sentiment, the potential for tokenized venture capital funds to bring liquidity and transparency to startup investing, and Cursor’s extraordinary growth—scaling to over $500M in ARR in …
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