Here’s an Idea is Tech Briefs' original podcast series features the stories behind today’s most innovative technologies and the inventors responsible for creating them.
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Welcome to the Talking Precision Medicine podcast. In this series, we sit down with experts on the application of AI and big data analytics in the drug discovery space. Our guests are innovators, business decision makers and thought leaders at the intersection of data and therapeutics. We discuss the promise, practice, challenges, and myths of AI in precision medicine. This show is brought to you by Genialis, and Rafael, our CEO, is your host.
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Anna Berkenblit & Sudheer Doss, PanCAN | On a mission to beat an ignoble killer: pancreatic cancer | TPM podcast #45
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46:10Today’s guests are Anna Berkenblit, Chief Scientific and Medical Officer at the Pancreatic Cancer Action Network, and Sudheer Doss, Chief Business Officer at PanCAN. The Pancreatic Cancer Action Network is the leading organization dedicated to advancing progress against pancreatic cancer. It empowers patients and caregivers, drives early detection …
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Najat Khan | Radical Transformation: Becoming a Medicines Company with End-to-End AI | TPM #44
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38:35Today’s guest is Najat Khan, Chief R&D Officer and Chief Commercial Officer at Recursion Pharmaceuticals. Recursion is widely recognized as one of the most visible—and so far, most successful—companies to emerge from the tech-bio movement. Many consider it the current industry leader. It has become an iconic name in the field of artificial intellig…
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Ryan Fukushima | Reinventing diagnostics: The superpower of not knowing what can’t be done | TPM #43
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43:19What a pleasure to welcome today’s guest, Ryan Fukushima, chief operating officer of TempusAI. Not only has Ryan helped build Tempus brick by brick from the earliest days, he is also CEO of Pathos AI, a biotech company using real world data and AI to develop true precision medicines. I don’t know how he juggles it all, but unless you’ve been hiding…
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The journey to the top of life sciences technology: a lifetime of listening and learning | Talking Precision Medicine #42
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47:34Today my guest is Joydeep Goswami, newly appointed President and CEO of the storied biotechnology company LGC. Joydeep is also a strategy advisor to Genialis. Join us as we discuss his remarkable career and lessons learned at each step of the way. Come on in and have a listen. Episode 42 links: TPM E42 for highlights and links from this e…
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The view from 30,000: Healthcare & life science AI in the cloud | Talking Precision Medicine #41
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37:10This episode features a conversation with Shweta Maniar, who leads the Healthcare and Life Science effort at Google cloud. In just a few short years, artificial intelligence has gone from the stuff of hype and fairy tale to powerful and ubiquitous tools for all aspects of R&D and healthcare delivery. Google has been central to this sea change. I di…
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What’s in a digital twin? Inventing new kinds of AI for biomedicine | Talking Precision Medicine #40
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47:02Our guest this episode is Charles Fisher, co-founder and currently Chief Scientific Officer of Unlearn.AI. Unlearn has been a leader in the advancement of Digital Twins as a tool to drastically improve the efficiency of clinical trials. Not only a visionary scientist and trailblazing entrepreneur, Charles is fearless with his hot takes. So sit back…
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Leave No Patient Behind—R&D Tools and Cutting Edge Diagnostics that Span the Globe | Talking Precision Medicine #39
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35:38What a genuine pleasure to sit with Thierry Bernard, CEO of Qiagen. As I told Thierry, Qiagen is a truly iconic brand for anyone who came up through molecular biology laboratories in the past 30 years. Their products were ubiquitous, and crucial, to the success of our research. In this conversation, Thierry talks about his global vision for precisi…
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Zola-007: Giving T-cells the license to kill | Talking Precision Medicine #38
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44:06What a pleasure to sit down with my long time colleague and friend, Art Krieg, to discuss his latest venture, Zola Therapeutics, and his adventures in the great outdoors. Art has launched and exited a number of innovative biotechs, each time delving deeper into mechanisms by which we can harness the immune system for therapeutic purposes. Join us a…
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Cell therapy for T-cell malignancies—the science and business of developing curative medicines for patients in need | Talking Precision Medicine #37
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39:01In this episode I chat with Dr Sarah Hein, co-founder and CEO of March Biosciences, a Houston Based biotech developing cell therapies for T-cell malignancies. Sarah is an old friend and colleague from our days as trainees at Baylor College of Medicine, where we both circulated among those with ambitions of entrepreneurship. Sarah has definitely mad…
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Tackling healthcare disparities and bridging the digital divide: it doesn’t have to be so hard | Talking Precision Medicine #36
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44:13This episode features two guests, Jennifer Goldsack and Yashoda Sharma, of the Digital Medicine Society, or DiMe. We’re going to get into the nitty gritty of healthcare disparities in terms of access and outcomes, and how digital solutions are a big part of the overall solution. Episode 36 links: TPM E36 for highlights and links from this epi…
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The Science and Art of De-risking Cancer Drug Development | Talking Precision Medicine #35
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31:27In this episode Genialis CEO Rafael Rosengarten sat down with Dr. Carolina Haefliger, head of translational medicine at Debiopharm, the privately held Swiss biopharma company focused on oncology drug development. They talked about de-risking promising new cancer drugs, and what it takes from the science to the team to the technologies. Episode 35 l…
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A New Minimally Invasive Approach to Spinal Cord Injury
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14:44Spinal cord injury affects 17,000 Americans and 700,000 people worldwide each year. Prognoses are often tragic and social costs exceed $2 million (U.S. and EU) in the first five years ofcare. A research team at NeuroPair, Inc. won the Grand Prize in the 2023 Create the Future Design Contest for a revolutionary approach to spinal cord repair. Dr. Yo…
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Professional grade software — a key ingredient in cutting edge biomedical discovery | Talking Precision Medicine #34
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31:38Today we turn the mic around, as our guest Adam Stasio hosts an excellent podcast of his own. Adam’s day job, however, is running SciMed, a boutique life sciences software development company. Adam and Genialis CEO Rafael Rosengarten discuss the state of scientific software, the importance of agility and communication, and approaches to building a …
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Patients are more likely to adhere to their treatment plans when drug-delivery devices are user-friendly. So, what can device developers do to ensure safety but also provide a positive user experience? Using human factors engineering, developers can design features to prevent errors and contribute to the successful use of the device. On this episod…
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Advances in integrated microelectronics have enabled a revolution in ever smaller and more powerful medical sensors. One such use is for detecting pressure in the eye. InjectSense has invented an implantable sensor that detects direct dynamic pressure in the eye and transmits high-fidelity data from inside the eye of a patient to their physician. O…
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How AI is Changing Military Aircraft Maintenance and More
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18:13On Nov. 2nd, the Department of Defense (DoD) published its 2023 Data, Analytics, and Artificial Intelligence Adoption Strategy, outlining how the agency will acquire and deploy AI-enabled systems in the future. David Mazar, Vice President of Strategy and Growth, SparkCognition Government Systems is the guest on this episode of Here’s an Idea. Ahead…
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New Medicines from Evolutionary Pathways: Using Comparative Genomics to Treat Human Disease | Talking Precision Medicine #33
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42:45Our guest today is Dr. Ashley Zehnder, co-founder and CEO of Fauna Bio. Fauna is a revolutionary young biotech company using comparative genomics of an array of non-traditional mammalian models to discover new therapeutic opportunities for people. What do ground squirrels have to do with treating battlefield trauma? Only one way to find out … Visit…
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Treatments for neurological disorders such as epilepsy, Parkinson's disease, dystonia, and other related neurological disorders often include invasive surgery to implant electrodes in specific brain regions to help control motor symptoms. But what if there weretechnologies that offered minimally invasive options while improving patient outcomes and…
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Dr. Brendan Mulvaney Talks China’s Space and SATCOM Strategy
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14:09Ahead of his participation in the 2023 Global MilSatCom conference and exhibition, Dr. Brendan Mulvaney joins the podcast to discuss China’s latest military space and satellite technology related developments. Dr. Mulvaney is the Director of the China Aerospace Studies Institute at National Defense University. He also served several tours in Califo…
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The Gripen E Jet's New Lithium-Ion Battery
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16:55The Gripen E is the latest variant of Saab's fighter jet that first achieved certification for military use and entry into service in December 2022. The Swedish aerospace manufacturer recently awarded a new design and development contract for a 24 volt lithium-ion battery to be developed by EaglePicher, a St. Louis, Missouri-based supplier of missi…
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The medical device industry landscape is becoming increasingly complex with an evolving regulatory environment. The focus is now data-centric systems vs. equipment-centric, creating a fundamentally different business model. What does this new normal look like and how can medical device and life sciences businesses best address it? On this episode o…
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Rapid and effective control of bleeding can be the difference between life and death in surgery, on the battlefield, and in emergency situations. Excessive bleeding can lead to a rapid drop in blood volume, causing hypovolemic shock, which can be fatal if not addressed promptly. By stopping bleeding quickly, medical personnel can prevent shock and …
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To achieve personalized medicine, start by getting the dose right | Talking Precision Medicine #32
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39:13In this episode, Genialis CEO Rafael Rosengarten sits down with Ajay Gopal, CEO and founder of Rx Studio. Rx Studio is a technology company using data science to tackle a major limitation to personalized medicine: drug dosing. Visit TPM E32 for highlights and links from this episode.
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This Electric Autonomous Drone Enables Networked Warfighter Communications
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28:50A California-based startup named Kraus Hamdani Aerospace has emerged as a unique entrant into the market for new commercial and military drone technologies with its K1000ULE fully electric autonomous unmanned aircraft system. The solar-powered glider has demonstrated its ability to fly non-stop for 26 hours, longer than any electric unmanned aircra…
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On this episode of Here's an Idea™, James F. Jordan, Healthcare & LifeSciences Expert, President of StraTactic, and the National Co-Chairman of the BIO Bootcamp, discusses where AI can have the greatest impact in medical technology and what medical device developers should consider as they integrate AI.…
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Automating Warehouse Inventory Monitoring with Drones
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15:31Efficient inventory management is crucial for manufacturing companies to maintain smooth operations. Pittsburgh-based Gather AI is using drones to automate inventory monitoring processes for warehouse operators to decrease the cost of inventory, improve productivity, and boost revenue. Sankalp Arora, CEO and Co-Founder of Gather AI, discusses how t…
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AI and Ethics in Healthtech: Who is Innovating Most? | Talking Precision Medicine #31
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34:41In this episode, Genialis CEO Rafael Rosengarten speaks with BCG management consultant and healthcare innovation expert Amy MacDougall. They discuss emerging trends in healthcare, the role of AI, ethics and more, as well as BCG’s recently released 50 Most Innovative Companies List. Visit TPM E31 for highlights and links from this episode.…
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Clinicians today are hampered by insufficient and delayed lab diagnostics. Nutromics has created a breakthrough technology that combines multiple DNA sensors with microneedles. The diagnostic platform does everything a blood test does and more: it is a lab-on-a-patch. On this episode of Here's an Idea™, Peter Vranes, CEO and Co-Founder of Nutromics…
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People first: building a company that inspires impactful work | Talking Precision Medicine #30
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51:06This episode, Genialis’ thirtieth, is a bit different from the previous ones. CEO Rafael Rosengarten has not one, not two, but three guests, including the entire leadership team at Genialis. The gang discusses Genialis’ twin quests to build a great place to work and a business that makes a positive impact on the world. Visit TPM E30 for highlights …
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The Natilus Blended Wing Body Autonomous Air Cargo Aircraft
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14:50Natilus was first established a startup in San Diego, California in 2016 with the goal of developing a blended wing body (BWB) autonomous air cargo carrying aircraft. In April, the startup completed the first flight of the sub scale prototype of its Kona aircraft. On this episode of Here's an Idea, Natilus CEO AlekseyMatyushev discusses their visio…
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Biotricity is connecting cardiologists to real-time patient data while empowering patients to help prevent and manage various heart diseases — which is the leading cause of death in the United States. On this episode of Here's an Idea™, Waqaas Al-Siddiq, CEO and Founder of Biotricity, discuss how the company is bridging the gap in remote monitoring…
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University of Arizona engineers have developed a new system that allows autonomous vehicles to scout out underground habitats for astronauts. On this episode of Here's an Idea™, Wolfgang Fink, Associate Professor of Electrical and Computer engineering at UArizona, discusses how the approach could help address one of NASA’s Space Technology Grand Ch…
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Amprius’ Electric Aircraft Battery Energy Density Breakthrough
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16:56Amprius Technologies has achieved a new battery energy density breakthrough of 500 Wh/kg with its lithium-ion cell, the Silicon Anode Platform. Mobile Power Solutions, an independent testing house offering battery regulatory compliance and performance testing, verified the Silicon Anode Platform's energy density performance. The results indicate th…
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The Future of Artificial Intelligence and Machine Learning in Avionics Systems
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17:42Artificial intelligence and machine learning are transitioning from future-facing buzzwords to a near term possibility for commercial and military aircraft avionics systems. In February, Intel published a jointly written white paper with Daedalean, a Switzerland-based startup and developer of artificial intelligence and machine learning software fo…
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Communication, the key to building community | Talking Precision Medicine #29
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44:54Our guest this episode is Dr. Susanna Harris, community lead at Vibe Bio. Susanna is a dedicated scientific communicator and an outspoken advocate for the mental health of PhD students and other science researchers. She has chronicled her journey from the academic lab bench to a venture incubator to a promising biotech company for a substantial soc…
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A new way to finance drug development, for rare disease and beyond | Talking Precision Medicine #28
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45:36In this episode, our host and Genialis CEO Rafael Rosengarten spotlights Vibe Bio. Vibe Bio is a new biotech aiming to disrupt how we finance drug development through stakeholder communities and cryptocurrency, starting in the rare disease arena. Our guest is Alok Tayi, co-founder and CEO of Vibe. Alok is a successful serial entrepreneur and a rare…
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What’s in a Name?: Endpoint Health’s Patient-Centric Northstar | Talking Precision Medicine #27
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43:16This episode features Jason Springs, co-founder and CEO of Endpoint Health, an ascendant precision therapeutics company. Jason is a serial entrepreneur, who with the co-founders of his previous company, is building Endpoint Health to bring together under one roof the data science, diagnostics and therapeutics necessary to achieve truly personalized…
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3D-Printed Lubrication System for Single-Use Engines
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10:20Effective lubrication is essential to any mechanical system. For example, it is responsible for providing a continuous flow of oil to the engine of the aircraft. As aircrafts have evolved, so have lubrication systems. Now, a Florida-based startup Zulu Pods, has developed the ZPod, a self-contained, sealed, oil tank and pump that can be installed in…
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Fabrics haven’t changed all that much. For years, a shirt has quite simply been a shirt. But a team at the Massachusetts Institute of Technology wants to add function to the fibers. What if your shirt, for example, contained electronics that could track your heartbeat or the heartbeat of your unborn child? A team from MIT and the Rhode Island Schoo…
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How to Make the Best Decisions (on the Moon)
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14:44Pharma industries, transportation services, the energy sector, and mining companies are looking for a new place to do business, and it’s more than 200,000 miles from Earth. The private sector is heading to the Moon – a world of potential resources like metal, water, and solar power, according to our guest on this week’s Here’s an Idea: Blair DeWitt…
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For some people, a critical link – the one sending signals from brain to body, the one connecting thought to action – does not work properly, or in some cases, has been severed entirely. Marcus Gerhardt, CEO and co-founder of the Salt Lake City, UT-based company Blackrock Neurotech, is creating a technology called a brain-computer interface. The ti…
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Recycling Lithium-Ion Batteries from Electric Vehicles
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10:11Over 145 million electric vehicles are set to take the road by 2030 and a major component of the new class of electric vehicles – lithium-ion batteries – is rarely recycled. Canadian battery recycling company Li-Cycle is aiming to change that through its sustainable process to provide an end-of-life solution for lithium-ion batteries, while creatin…
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Taking charge of your health future with wearables and AI | Talking Precision Medicine #26
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33:33In this episode 26, our host Rafael sits down with Harry Glorikian. Harry is an investor, author, podcaster and veteran of the healthtech industry. Harry walks us through his latest book, The Future You, and expounds on the ways that wearable devices, personal health data and artificial intelligence are changing healthcare as we know it. Visit TPM …
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Going for the Gold with Aerodynamic Luge Sleds
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12:39Luge is one of the three sliding sports on the program at the 2022 Winter Olympics being held in Beijing this month. The sport requires athletes to barrel down an ice track on small sleds accelerating to speeds of nearly 90 mph. Traditionally, lugers design and build their own sleds, often through trial and error. Now, Clarkson Mechanical and Aeron…
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Dr. Frits Bliek and his team at Ocean Grazer are building an "Ocean Battery" that brings hydrodam technology to the sea. On this episode of Here's an Idea, Bliek, CEO of the Netherlands-based energy company, talks about an innovative idea for power that involves plastic bags, underground reservoirs, and a big drill.…
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A Major Role for Microneedles in Drug Delivery, Post-Pandemic
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28:11Who really likes needles? A brand-new episode of our Tech Briefs podcast series Here’s an Idea™ explores the emergence of a drug-delivery patch made of micro-needles. The Velcro-like option is less painful – and more effective, it turns out. And the devices are especially valuable during a pandemic. See acast.com/privacy for privacy and opt-out inf…
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Real-Time Multiplexed Biomarkers: The Next Generation of Continuous Monitoring | Talking Precision Medicine #25
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31:47Earlier this summer, Rafael sat down with Peter Vranes and Hitesh Mehta, co-founders of Nutromics. Nutromics is developing a next generation lab-on-skin, a wearable device for continuous monitoring of health-critical biomarkers. Let’s get right to it. Visit TPM 25 for highlights and links from this episode.…
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Reinventing the Hearing Aid: From DIY Devices to Brainwave Monitoring
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29:19We speak to four researchers about their hearing innovations: a 3D-printed stent for collapsed cartilage, a one-dollar hearing aid that can be built in an hour, a "mind-reading" hearing aid that solves the cocktail party problem, and a brain monitor for cochlear-implant calibration. See acast.com/privacy for privacy and opt-out information.…
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Fostering Patient Journeys Around the World | Talking Precision Medicine #24
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40:42Our guest is Dr. Angeli Moeller, Head of Pharma International Informatics at Roche. Angeli and our host, Rafael, discuss data science in the big pharma leagues; geek out on data standards; and dive deep on patient data rights and barriers to care. Visit TPM E24 for highlights and links from this episode.…
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Tech Briefs talks to three researchers who are finding ways to automate surgical tasks, from suturing, to spotting tumors, to operating one of the biggest machines in surgery today: The Da Vinci. Ken Goldberg of UC Berkeley discusses how his team got the Da Vinci to autonomously perform a training exercise with "superhuman" speed and accuracy. See …
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