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“Two Guys Talking $#it” is a podcast where two Gastroenterologists break down complex topics into engaging, educational, and occasionally humorous conversations. From liver health to gut microbiota and everything in between, A/Professor Jonathan Segal and Dr James Haridy deliver insights, share the latest research, and discuss clinical pearls with the odd guest in tow. Comments, suggestions, questions please contact us on twitter @2guystalkingit or leave a comment below..
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Today we welcome two world-leading dietitians to talk all things diet in IBD and IBS.... A/Prof Emma Halmos is a senior research dietitian at Monash University and the Alfred Hospital. Her scientific achievements have had a major impact in clinical practice nationally and internationally. The most notable was the pivotal feeding study that demonstr…
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Summary Dr Gideon Hirschfield is a leading expert in autoimmune liver diseases, including PSC, PBC, and autoimmune hepatitis. He’s helped shape how these conditions are understood and managed around the world, combining cutting-edge research with a real passion for patient care. Today he discusses his work with autoimmune liver diseases, particular…
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This is a really special episode with an incredible doctor (Jon says "the best clinician I have ever met"). Today we welcome Dr Simon Gabe, an internationally renowned expert in intestinal rehabilitation. Dr Simon Gabe is a consultant in gastroenterology & intestinal rehabilitation at St Mark’s Hospital and chair of the NHS National Reference Centr…
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Jon and James welcome Dr Beatriz Gros, a leading expert in inflammatory bowel disease (IBD). They discuss key findings from the recent European Crohn's and Colitis Conference in 2025. Dr. Beatriz Gros (X: @bealoquebea Instagram: @dr.beatrizgros) is a consultant gastroenterologist based in Córdoba, Spain, specializing in inflammatory bowel disease (…
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We very excited about the episode today! We are joined by A/Professor Jason Tye-Din - a leading expert in coeliac disease and immune-mediated gut disorders. He is Coeliac labratory head at the Walter and Eliza Hall Institute of Medical Research, a Mathison Centenary Fellow at the University of Melbourne, and consultant Gastroenterologist at the Roy…
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Professor Alex Ford is a renowned researcher in Gastroenterology, specializing in Disorders of Gut-Brain Interaction (DGBIs). Based at the University of Leeds, he has authored numerous high-impact studies on conditions like irritable bowel syndrome (IBS) and functional dyspepsia. With a focus on evidence-based treatments and advancing our understan…
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Every podcast is incomplete without a 'best of' episode from the previous year. In this episode Jon and James talk about their big learnings / seminal papers / themes of 2024 in Gastroenterology and Hepatology. We wish we could have included more! As always, please leave questions/comments either below or on our X (@2guystalkingit).…
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Episode #02: Checkpoint conversations In the first full episode, we tackle the rising challenge of managing colitis and hepatitis triggered by immune checkpoint inhibitors. From recognizing these entities to exploring (non) evidence-based management strategies. Join us for a conversation packed with insights, or if you just want to hear Jon try and…
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Hello world.. Welcome to Two guys talking **it - a podcast designed for gastroenterologists and hepatologists or anyone interested in the field. Each week, join Jon and James as we bring you expert discussions, the latest research, and practical clinical insights amongst a lot of talking **it.. In this episode we briefly introduce the podcast. Bear…
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