Alexander Schacht And Benjamin Piske Biometricians Statisticians And Leaders In The Pharma Industry public
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The Effective Statistician - in association with PSI

Alexander Schacht and Benjamin Piske, biometricians, statisticians and leaders in the pharma industry

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The podcast from statisticians for statisticians to have a bigger impact at work. This podcast is set up in association with PSI - Promoting Statistical Insight. This podcast helps you to grow your leadership skills, learn about ongoing discussions in the scientific community, build you knowledge about the health sector and be more efficient at work. This podcast helps statisticians at all levels with and without management experience. It is targeted towards the health, but lots of topics wi ...
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Interview with Kaspar Rufibach What You’ll Learn in This Episode: ✔ The true definitions of interim, final, primary, confirmatory, and updated analyses ✔ Why a “final analysis” doesn’t always mean “last analysis” ✔ How language choice can impact stakeholder trust and regulatory interpretation ✔ The operational vs. statistical meaning of “stopping a…
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Interview with Holger Fröhlich What You’ll Learn in This Episode: ✔ What synthetic data actually is – and what it isn’t ✔ The benefits and challenges of using synthetic data in clinical research ✔ Real-world use cases, from early dementia diagnosis to trial simulation ✔ How digital twins could help predict patient outcomes ✔ Why synthetic data migh…
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Friday Episode with Alexander 🧠 What You’ll Learn: ✔ How I improved my English on the job (despite not having great grades in school) ✔ Why consuming high-quality English content (like podcasts, TED Talks, and books) made a big difference ✔ Tips for writing regularly—even journaling—and using tools like ProWritingAid ✔ How slowing down when speakin…
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Interview with Daniel Sabanés Bové What You’ll Learn in This Episode: ✔ Why interactive visualizations are such a game changer ✔ How R-Shiny makes scenario planning and data exploration easier ✔ What to consider before you even start coding ✔ Common mistakes to avoid with larger Shiny apps ✔ How to structure your code for long-term success and main…
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Friday Episode with Alexander Schacht 🧠 What You’ll Learn: ✔ Why I believe “soft skills” is the wrong term—and what we should call them instead ✔ How I built trust in just 15 minutes with someone I'd never met before ✔ The story behind a data visualization that got standing ovations ✔ A negotiation win that shifted how I think about value ✔ How the…
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Interview with Daniel Sabanés Bové What You’ll Learn in This Episode ✔ Why creating R packages is a game-changer for code reuse and collaboration. ✔ The most common challenges we face when reusing code—and how packages help solve them. ✔ When it actually makes sense to start writing a package (spoiler: earlier than you think). ✔ Useful tools like u…
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Interview with Necdet Gunsoy What You’ll Learn in This Episode ✔ Necdet’s Journey ✔ Breaking Down Key Market Access Concepts ✔ The Real Cost of Poor Collaboration ✔ How We Can Work Together More Effectively ✔ Looking Ahead: The Impact of Joint Clinical Assessment (JCA) Why You Should Listen If you work in biostatistics, health economics, or market …
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Friday Episode with Alexander Schacht What You’ll Learn in This Episode ✔ Why logic alone isn’t enough to persuade others ✔ How emotions play a crucial role in decision-making ✔ The importance of credibility and trust in influencing others ✔ Practical strategies to make your arguments more compelling ✔ How to tailor your message to different audien…
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Interview with Kaspar RufibachIn this episode of The Effective Statistician, I sit down with Kaspar Rufibach to tackle a topic that affects statisticians every day—how to interpret p-values, confidence intervals, and statistical hypotheses. We explore the differences between Fisher’s and Neyman-Pearson’s approaches, clear up common misconceptions, …
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Friday Episode with Alexander Schacht Key Points: Building Influence Negotiation Trust Pillars Collaboration Proactivity Impact Actionable Strategies Building influence as a statistician isn’t just about being heard—it’s about driving better decisions, improving team dynamics, and ultimately making a greater impact on patient outcomes. The strategi…
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Interview with Peter M. Wehmeier Key Points: Workload & Mental Well-being Five Dimensions of Self-Management Relationships Priorities Decision-Making Taking Action Stress Management Peter’s Workshops Empowerment Take control of your well-being and success by mastering self-management. In this episode, you’ll learn practical strategies to reduce str…
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Interview with Darko Medin Key Points: AI Challenges: Hallucinations, Accuracy, Reliability AI Solutions: Validation, Cross-checking, Domain-specific rules Use Cases: Oncology, Precision Medicine, Drug Discovery High-dimensional Data: Hidden patterns, Complex datasets AI Agents: Semi-autonomous, Goal-driven, Multi-step processes Interpretability vs…
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A book review with Steve Mallett and Alun Bedding Key Points: Slow Productivity Three Principles Workload Management Meetings Seasonality Overhead Tax Quality vs. Perfectionism Time Management Mindset Shift Slow Productivity offers valuable insights on working smarter, not just harder. By applying its principles, we can reduce stress, improve focus…
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Interview with Justin Belair Key points: Causal Inference – Hot topic in statistics Justin Belair – Guest, statistician, book author Book Writing – Motivation, challenges, process Balancing Content – Theory, real-world applications, coding exercises Effective Writing – Strategies, focus, overcoming obstacles Practical Tools – Applying causal infere…
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Discussion with Alexander Schacht Key points MDLC Introduction Leadership Growth Career Development Three Tiers Learning Formats Real-World Application Impact on Healthcare Membership Options How to Join The Medical Data Leaders Community (MDLC) offers a unique opportunity to grow your leadership skills, expand your influence, and drive meaningful …
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Friday Episode with Alexander Schacht Key points Endless To-Do Lists Causes of Overload Problems Key Strategies: Prioritization Single Bridge System Task Breakdown Say No & Delegate Two-Minute Rule Big-Picture Thinking Leadership Skills Medical Data Leaders Community Call to Action Take back control of your time and break free from endless to-do li…
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Discussion with Alexander Schacht Key points: Meeting Overload Root Causes Impact Strategy 1: Priorities Strategy 2: Meeting Practices Strategy 3: Saying No Long-Term Approach Bonus Take back control of your calendar and focus on what truly matters. Set clear priorities, improve meeting practices, and say no to unnecessary commitments. These strate…
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Friday Episode with Alexander Schacht Key points Key Points from the Episode: Long Hours Trap Workload Pressure Belief Shifts Limiting Beliefs: "Hard Work = Value" "Busyness = Productivity" "Perfectionism" "Delegation is Weakness" Productivity Strategies: Prioritization Meetings Communication Automation & Templates Career Impact Health & Relationsh…
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Interview with Steve Dirkse Key Points: GAMS Overview Distinction Applications System Components Examples Mathematical Functions Convexity Getting Started Documentation and Training Final Advice GAMS opens up a world of possibilities for solving complex optimization problems, from logistics and healthcare to business and beyond. Whether you're a st…
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Discussion with Alexander Schacht Key points Hustle Culture Mental and Physical Health Long-Haul Leadership Continuous Personal Growth Adaptability and Change Nurturing Relationships Values and Principles Prioritizing Well-Being Building Consensus Leaving a Legacy Adopting the mindset of a long-haul leader isn’t just about improving your work—it’s …
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Discussion with Alexander Schacht Key points Negotiation as an Essential Skill Examples of Negotiation Importance of Preparation Effective Strategies Professional Impact Broader Application Practical Insights Negotiation transforms your professional and personal interactions, empowering you to advocate for yourself and achieve better outcomes. In t…
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Friday Episode with Alun Bedding Key Points: Trust as Leadership Backbone Leadership is a Choice Leadership vs. Management Authenticity Inspiration vs. Motivation Trust Equation Nine Habits of Trust: Deliver Be open Be honest Be brave Coach Be humble Evangelize Be consistent Be kind Trust is Earned Empathy and Kindness Trust as a Bank Account Trust…
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Discussion with Alexander Schacht Key points New Year Episode Book Announcement Personal Journey Target Audience Content Overview Fictional Narrative Chapter Structure Book Format Launch Party Ordering Info Don’t miss this inspiring episode of The Effective Statistician! Whether you’re curious about the process of writing a book, looking for action…
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Friday Episode with Alun Bedding Key Points: Imposter Syndrome Personal Experience Self-Doubt Chimp Paradox (Dr. Steve Peters) Inner Chimp Confidence Slowing Down Reframing Negative Experiences Learning Opportunities Recognizing Strengths Building Confidence Growth Mindset Success Recognition Feedback as a Gift Managing Self-Doubt Actionable Strate…
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Discussion with Alexander Schacht Key points: Effective Leadership Growth Cycle Action-Oriented Communication Impactful Initiatives Continuous Improvement Practical Tips Leadership Essentials Statistical Parallel Take Charge Becoming a better leader starts with taking intentional steps to learn, apply, and reflect on your actions. This episode offe…
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Friday Episode with Alun Bedding Key Points: Lifestyle-Centric Career Planning Vision Boards Goal Setting Quality Over Quantity Periodic Review Books and Inspirations Balance and Avoiding Burnout Coaching Insights Planning for 2025 doesn’t have to be overwhelming—it can be a powerful exercise in aligning your goals with your ideal lifestyle and lon…
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Interview with Teppo Huttunen Key points: Dose Selection Challenge Limitations of 3+3 Design BOIN Design Backfilling Efficacy vs. Safety Statisticians’ Role Practical Challenges FDA Guidance Cross-Functional Approach Industry Trends Cost & Timeline Estimation Understanding dose selection in immune-oncology is crucial for developing safer and more e…
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Friday Episode with Alun Bedding Key Points: Sharpen the Saw Stephen Covey Continuous renewal Four Dimensions of Renewal Physical Mental Social Spiritual Practical Strategies Take breaks Solve problems Block time Reflect Key Insights Balance across dimensions Avoid multitasking Curiosity and proactive mindset Sharpening the saw is about investing i…
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Interview with Jack Elkes Key points: Digital health interventions: Definition, scope, examples. Engagement: Definition, importance, complexity. Measurement challenges: Multidimensional data, variability, arbitrary definitions. Mental health focus: Apps, virtual reality, stigma reduction, barriers to care. Cluster analysis: Grouping users, multidim…
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Interview with Annie Wright Key points: Environmental Impact Carbon Footprint Drivers Decentralized Trials Study Design Simplification Protocol Amendments Waste Management Greener Initiatives Technology Adoption Awareness and Collaboration Call to Action CO2 Calculators Public and Private Collaboration Clinical trials play a vital role in advancing…
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Interview with Kaspar Rufibach Key points: Non-Proportional Hazards: Understanding when and why the proportional hazards assumption fails. Hazard Functions: Differences between survival functions and hazard functions; interpreting dynamics over time. Data Visualization: Importance of visualizing hazard functions alongside Kaplan-Meier curves. Clini…
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Interview with Aziza Yormizaeva and Klaus Breuer Key points: Leadership: Building trust, inspiring growth, and prioritizing collaboration. Mentorship: Klaus guiding Aziza to discover her passion for statistics. Professional Growth: Empowering team members to learn and succeed. Authenticity: Honest communication and standing by data-driven insights.…
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Interview with Oscar Segurado, MD PhD Key points: Gene Therapy Uniqueness: Differences from traditional drug development Safety & Dosing: Single-dose approach, safety considerations Statisticians' Role: Essential contributions in planning and analysis Guest Background: Oscar’s expertise in academia, med tech, biopharma, Humira development Clinical …
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Interview with Avery McIntosh and Oleksandr Sverdlov Key points: Gene Therapy Potential Role of Statisticians Guest Experts Overview Challenges Statistical Innovation Current Impact Future Outlook Audience Insight Podcast Goals In this episode, we dive deep into the science, the ethical hurdles, and the innovative statistical methods that make gene…
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Interview with Carrie Li Key points: Clinical Development Plan (CDP): strategy for compound progression Early Decisions: impact on clinical phases, timeline, cost Statistical Role: balancing science, speed, and cost Target Product Profile (TPP): guides CDP objectives Cross-functional Collaboration: clinical, commercial, regulatory teams Big Pharma …
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Interview with Pietro Mascheroni Key points: Large Language Models (LLMs): Role in transforming work processes, especially in AI and machine learning. Practical Applications: Document retrieval, data exploration, code refinement. Human Oversight: Importance of keeping human input in AI-assisted processes. Communication: AI's potential to improve te…
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Interview with Swarna Khare Key points: Expanding Careers: Statisticians moving beyond traditional statistics roles. Transferable Skills: Data interpretation, strategic thinking, communication. Career Transition: Swarna’s journey from statistician to strategic roles. Broader Impact: Using statistical skills in non-technical positions. Practical Adv…
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Interview with Taina Pereenniemi Key points: Introduction to Notion Taina’s Journey Key Features of Notion Collaboration & Integration Productivity Benefits Generative AI Replacing Other Tools Getting Started with Notion Paid Features Conference Workshop Taina shares invaluable tips on getting started with Notion and highlights its potential to rep…
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Interview with Daniel Sabanés Bové Key points: Statisticians and software engineering: Learning from software engineering practices to improve statistical work. Daniel Sabanés Bové career path: Transition from biostatistician at Roche to data scientist at Google, and return to healthcare. Software engineering principles: Importance of clean coding,…
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Interview with Chantelle Cornett Key points: Predictive Models: Forecast future outcomes based on historical data. Model Building: Process of analyzing data, training, and testing models. Validation: Ensures model reliability and accuracy. Healthcare Applications: Use in survival rates, treatment responses. Technical Discussion: Pruning models, int…
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Interview with Paolo Eusebi Key Points: AI in Daily Work GitHub Copilot Code Suggestions Learning Tool R Studio Integration Productivity Boost Data Privacy Future of AI As AI continues to revolutionize the way we work, tools like GitHub Copilot offer incredible opportunities to enhance productivity, simplify complex tasks, and accelerate learning. …
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Friday Episodes with Alexander Schacht Key Points: Audience focus Practice Setup mastery Slides Engage with slides Stand up Visibility Vocal variety Breathing Gestures Self-assessment Learn how to transform your presentation skills and approach public speaking with confidence and ease. By focusing on your audience, practicing regularly, mastering y…
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Interview with Stephen Senn More key points: Role of Luck: Influence of luck in career development. Humility: Importance of staying humble in professional growth. Continuous Learning: Emphasis on lifelong learning and adapting. Career Decisions: Pivotal choices that shaped Stephen Zenn’s career. Insights: Valuable lessons from decades of experience…
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Friday Episode with Alexander Schacht Key points: Avoid clutter Separate slide sets Focus on key takeaways Use visuals Engage with storytelling Simplify slide titles Limit bullet points Avoid full sentences Leverage contrast Build step-by-step Strong finish In this episode, I cover essential tips for crafting slides that truly engage and enhance yo…
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Interview with Francois Vandenhende Key points: AI in Clinical Research: Exploring the impact of artificial intelligence on clinical research and development. Francois’ Experience: Insights from Francois, a seasoned expert with nearly 30 years in the pharmaceutical industry. Transition to AI: Francois’ journey from traditional statistical methods t…
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Friday Episode with Alexander Key points Resonance: What makes a presentation resonate with the audience? Memorability: Turning a simple delivery into something unforgettable. Ethos: Establishing credibility and trust with your audience. Logos: Presenting logical arguments, data, and evidence. Pathos: Creating an emotional connection with the audie…
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Interview with Pablo Orosco Joerger Key points:Biostatistics and IT Intersection: Exploring the relationship between biostatistics and IT. Evolution of Technology: Shift from mainframes and standalone PCs to cloud computing. Role of IT: Importance of IT in supporting statistical practices. Hardware Requirements: Necessary hardware and software for …
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Friday Episode with Alexander Key points: Elevate presentation skills Ask critical questions Transform presentations Inspire action Influence decision-makers Communicate complex ideas Master fundamentals Effective communication strategy By asking yourself these five essential questions before you even open PowerPoint, you can create presentations t…
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