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Extend with Darshan Shah, MD is a podcast dedicated to cutting-edge science, research, tools, and protocols designed to help you extend your healthspan. Starting my medical journey at 16 and becoming one of the youngest doctors in the country, studying and training at the Mayo Clinic, Harvard Business School, Singularity University and other prestigious institutions, becoming a board certified surgeon and accumulating over two decades of practice, I have discovered that a mere 20% of health ...
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Welcome to Hello Hormones with me, Dr. Carrie Jones! A podcast where we explore how to make friends with our hormones so we can survive—and thrive—through our 30s, 40s, 50s and beyond! I’m Dr. Carrie Jones—a holistic functional medicine doctor, hormone nerd, and women’s health advocate who’s spent over 20 years helping women understand their bodies and navigate all the twists and turns of hormone changes. I’ve seen it all—from the frustrating weight gain and brain fog to the mood swings, low ...
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You’re not in the mood. You’re not even in the mood for life. The spark is gone, your libido left the chat, and if one more person tells you to “just relax” or “get out of your head,” you might actually scream. In this episode, I’m joined by the brilliant Dr. Nan Wise, neuroscientist, sex therapist, and author of Why Good Sex Matters, to talk about…
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What if everything you've been told about preventing heart disease is only half the story? In this episode of Extend, I sit down with Dr. Joel Kahn, a pioneering preventive cardiologist who's spent decades challenging the traditional approach to cardiovascular medicine. We explore why the 1961 Framingham risk factors represent an incomplete picture…
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Why can't you open that jar anymore? Why does getting up from a chair feel harder than it used to? In this episode of Extend, I sit down with Dr. Amy Shah to explore the strength crisis happening to women in perimenopause. We dive into the simple tests that reveal where you're losing ground—and why most women are shocked by their results. We also s…
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You thought hormone therapy would fix everything. Instead, you're feeling moody, foggy, sleepless, or just kind of... off. Your bestie says it changed her life. Social media says it's the holy grail. So why isn’t it working for you? In this episode, I’m walking you through five reasons your hormone therapy might be falling flat, and what to do abou…
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What if I told you there's an organ in your body with more cells than the Milky Way has stars—and most doctors barely think about it? In this episode of Extend, I sit down with Dr. Zain Kassam, a gastroenterologist turned microbiome researcher who's pioneering how we understand the trillions of organisms living in and on us. We dive into why your g…
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Oxidative stress. Toxin overload. Immune dysfunction. These aren't separate problems—they're all symptoms of your body working overtime on one exhausting job. In this episode of Extend, I sit down with Dr. Nayan Patel, a pharmacist who's dedicated his career to understanding glutathione—the molecule your body produces more than any other. We break …
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Your gut is a mess. Your sleep is trash. Your hormones? All over the place. But your doctor just tells you “it’s normal” and hands you a pat on the back (with maybe a side of birth control). Sound familiar? In this episode, I’m joined by my fabulous friend and fellow hormone nerd Esther Blum, and we’re getting real about what actually happens to yo…
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Low energy, brain fog, and poor recovery aren’t just part of getting older—they’re often signs that your cells are underperforming. And one major reason? They’re starved for oxygen. In this episode of Extend, I talk with Dr. Scott Sherr, a hyperbaric medicine specialist who helps patients and doctors worldwide use oxygen therapy to restore cellular…
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Fatigue, brain fog, joint pain, blood pressure that won’t budge, these aren’t isolated symptoms. They’re your cells signaling that something’s off. In this episode of Extend, I sit down with Dr. Bill Rawls, a board-certified OB/GYN who now focuses entirely on cellular health. We explore why most chronic illness isn’t about your diagnosis, it’s abou…
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You’ve had questions—and I’ve seen them in the YouTube comments, DMs, and emails. In this episode, I’m answering the top eight questions I get asked all the time about perimenopause. Because let’s face it… no one really prepares us for this phase, and it can feel like your body is doing things you don’t recognize. From why symptoms like anxiety and…
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Your doctor says your health problems are genetic, so you're destined for the same fate. But what if that's completely wrong? In this episode of Extend, I'm joined by Professor Tim Spector, one of the world's leading microbiome researchers, to reveal the truth: your gut bacteria have more control over your health than your genes do. We explore Tim'…
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What if the real reason you’re gaining weight, feeling wired, or struggling to nourish your family isn’t about willpower—but the culture you live in? On this episode of Extend, I’m joined by Shawn Stevenson—nutritionist, bestselling author, and host of The Model Health Show—to explore how our food environment, not personal discipline, is fueling th…
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Are your hormones making you feel broken, inflamed, and totally not yourself? You’re not alone if you’ve hit your 40s or 50s and suddenly feel like your metabolism has tanked, your joints hurt, your mood is unpredictable, and your body just won’t cooperate. In this episode of Hello Hormones, I sit down with Dr. Tyna Moore to talk about the messy, c…
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Back pain is one of the most common health issues—but it’s also one of the most misunderstood. In this episode of Extend, I’m joined by Dr. Grant Elliott, a physical therapist and founder of RehabFix, to unpack the real reasons people stay stuck in chronic pain and what it actually takes to recover. We break down why most diagnoses like sciatica or…
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You’re bloated. Tired. Anxious. Maybe even burnt out. You’ve tried the diets, the supplements, the meditation apps… But you’re still not healing. Why? In this episode of Extend, I’m joined by Elissa Goodman, a holistic health expert and cancer survivor, to explore the deep connection between gut health, inflammation, and overall well-being. We dive…
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Everyone talks about hot flashes and night sweats. But what about the symptoms that make you wonder if you’re just losing your mind? You go to the doctor. You get labs done. You’re told you’re “fine.” But you still don’t feel like yourself—and nobody’s giving you real answers. In this episode, I’m pulling back the curtain on the lesser-known (but i…
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You’ve probably heard the term “bioidentical hormones” tossed around like a wellness buzzword—but is it actually legit or just marketing fluff? Some people swear by them. Others say they don’t even exist. So what’s the real deal? In this episode, I’m clearing up all the confusion around bioidentical hormones, what they really are (and aren’t), and …
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What if your bloating, fatigue, or fertility struggles aren’t separate issues, but signs of a deeper imbalance no one’s connected yet? In this episode of Extend, I’m joined by Dr. Robin Berzin, founder of Parsley Health, and we dig into how functional medicine uncovers the why behind your symptoms and why conventional care keeps missing it. We talk…
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What if the root cause of burnout, inflammation, and hormone dysfunction isn’t just physical—but energetic? In this episode of Extend, I sit down with Dr. Pedram Shojai—Taoist monk, doctor of Oriental medicine, and author of The Urban Monk—to explore how ancient wisdom meets modern health. We unpack why true healing requires addressing your qi (lif…
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What if your exhaustion, brain fog, or cravings aren’t a motivation problem—but a sleep problem no one’s diagnosed yet? In this episode of Extend, I’m joined by Dr. Michael Breuss, a sleep specialist, and we dig into why so many high performers are chronically under-recovered, why sleep disorders go undetected for years, and how wearables are both …
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Snappy one minute, crying at a dog food commercial the next? If your moods, sleep, or periods are all over the place, your progesterone might be waving a big hormonal red flag—and you’re not imagining it. In this episode of Hello Hormones, I walk you through the top 4 signs of low progesterone and how this one hormone can quietly sabotage your mood…
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Most people focus on physical health. But after years of practicing medicine, I’ve seen this truth again and again: you can’t heal your body if your mind and nervous system are stuck in survival mode. In this episode of Extend, I sat down with Kelly Gores, creator of HEAL and founder of WellSet, to explore how trauma, stress, and emotional blocks d…
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What if aging isn’t just inevitable—but programmable? In this episode of Extend, I sit down with Dr. Kara Fitzgerald, pioneering epigenetic researcher and author of Younger You, to explore how your daily choices—food, movement, sleep, stress—can literally rewire your genes to slow down aging. We unpack her groundbreaking study showing biological ag…
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Think low estrogen is just about hot flashes and night sweats? Think again. From your skin to your mood to your gut, estrogen impacts all 12 systems of your body—which means the symptoms can show up in some unexpected (and frustrating) ways. In this episode of Hello Hormones, I break down 4 surprising signs your estrogen may be too low—like thinnin…
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Most people are treating stress with the wrong tools, and it’s silently sabotaging their longevity. In this episode of Extend, I sit down with Jen Batchelor, Ayurvedic health optimizer and co-founder of Kin Euphorics, to talk about what your nervous system actually needs to feel calm, connected, and well. We dive into what adaptogens are really doi…
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What if your real age isn’t on your driver’s license—but buried in your biology? In this episode of Extend, I’m joined by Chris Mirabile, founder of NOVOS and one of the few people actually slowing down his pace of aging. We break down why the average person is aging faster than they realize, and how mainstream medicine is decades behind when it co…
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You asked your doctor to “test everything”—hormones, thyroid, nutrients—and they said, “You’re fine.” But you don’t feel fine. You’re still tired, gaining weight, feeling anxious, not sleeping, or just not you anymore. Spoiler alert: basic labs often miss what’s really going on. In this episode of Hello Hormones, I break down why “normal” doesn’t a…
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Most supplements don’t work. Some might actually harm you. That’s the hard truth no one in the $50 billion supplement industry wants to say out loud—but we will. In today’s episode of Extend, I’m joined by Steve Martocci, co-founder of SuppCo, to expose what’s really going on behind the labels. We break down why “clinically dosed” means nothing, wh…
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What if the reason you can’t focus, feel chronically overwhelmed, or keep slipping into the same unhealthy habits… isn’t a discipline problem, it's your brain’s biology working against you? In this episode of Extend, I'm joined by Dr. Austin Perlmutter, board-certified internal medicine physician and neuroscientist, to explore how inflammation hija…
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If your hormones have been throwing tantrums lately—hello mood swings, weight changes, fatigue, and wild periods—you’re not alone. And no, it’s not just “getting older.” In this episode of Hello Hormones, I’m sharing the 5 biggest things I wish I had done sooner to support my hormones—so you don’t have to learn the hard way. From skipping strength …
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In this episode of Extend, we’re digging into one of the most dangerous—and most overlooked—drivers of heart disease: LP(a). You could have a clean lifestyle, normal labs, and still be at high risk for a heart attack or stroke. Why? Because LP(a) isn’t included in standard cholesterol tests—and 1 in 5 people have elevated levels without knowing it.…
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If you've skipped your period for 6, 9, or even 11 months and you're still waiting to hit that magical 12-month mark that makes it “official,” you're in what I call stage 3. And while the guidelines don’t formally recognize this phase, it’s one of the most intense, confusing, and overlooked stages of all. In this episode of Hello Hormones, I explai…
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In this episode of Hello Hormones, I break down what happens in stage 2, why it can feel confusing or even scary, and what to expect over the next 1–3 years as your body transitions toward menopause. I’ll walk you through the hormone shifts, symptoms, lab markers, and lifestyle changes that matter most in this phase—so you can feel informed instead…
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What if the reason you're tired, inflamed, or not recovering the way you used to has nothing to do with aging, and everything to do with your NAD system being under attack? In this episode of Extend, I’m joined by Dr. Charles Brenner, the scientist who discovered nicotinamide riboside (NR) and one of the leading experts on NAD metabolism. We unpack…
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In this episode of Hello Hormones, I walk you through everything you need to know about stage one of perimenopause—what it actually is, how it’s defined, and the real-life symptoms I see every day in women (and have experienced myself). We talk about what your lab work might show, why your cycles are starting to shift, and how to spot early hormone…
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Most people know mindset matters, but almost no one knows how to actually train it for better health, performance, and longevity. In today's episode of Extend, I'm joined by David Nurse, NBA mindset coach and best-selling author. We dive deep into why mindset is the real missing piece in most health optimization plans, and how flow states, identity…
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What if the hidden toxins in your everyday life are secretly sabotaging your health, hormones, and longevity? Most people underestimate how deeply their health is impacted by toxins—and conventional medicine isn’t addressing the root of the issue. In this episode of Extend, I'm joined by Dr. Aly Cohen, renowned integrative rheumatologist, environme…
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Welcome to Hello Hormones with me, Dr. Carrie Jones! A podcast where we explore how to make friends with our hormones so we can survive—and thrive—through our 30s, 40s, 50s and beyond! I’m Dr. Carrie Jones—a holistic functional medicine doctor, hormone nerd, and women’s health advocate who’s spent over 20 years helping women understand their bodies…
  continue reading
 
In this episode of Extend, we’re rethinking everything you’ve been told about cholesterol. For decades, the focus has been on lowering LDL, but that’s only part of the story. The truth? LDL and total cholesterol are outdated metrics. If you're still relying on those alone to assess your heart health, you’re missing the bigger picture. I’ll break do…
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What if the secret to better energy, fat loss, and gut health wasn’t more discipline… but a smarter strategy? Most people are hacking the wrong system—and it’s backfiring. In this episode of Extend, I’m joined by Joel Greene, creator of the VEEP Nutrition System and one of the most innovative minds in metabolic health. We break down the science beh…
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What if our food system wasn’t designed for our health, but for shelf life, convenience, and corporate profit? In today’s episode of Extend, I’m joined by Ricky Silver, CEO of Daily Harvest, who brings a rare inside-the-industry view of how our food system really works, and how we can change it. We explore how government subsidies, processed foods,…
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What if the reason your supplements aren’t working has nothing to do with your body—and everything to do with what’s in the bottle? In this episode of Extend, I’m joined by biochemist and ingredient formulator Shawn Wells, a leading voice in evidence-based supplementation and mitochondrial health. Together, we uncover why so many products fail to d…
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What if menopause didn’t have to be a challenge, but an opportunity? In this episode of Extend, I’m joined by Zora Benhamou, host of the Hack My Age podcast, to challenge the common narrative around menopause. Zora shares a refreshing perspective that empowers women to see this stage of life as a chance for reinvention, growth, and better health. W…
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Brain fog, forgetfulness, and lack of focus are becoming the norm, but they don’t have to be. In this episode of Extend, I’m joined by Jim Kwik, a world-renowned brain coach and author of the bestselling book Limitless, to uncover how to unlock your brain’s full potential. We dive into the science of neuroplasticity, daily habits that sabotage your…
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In today’s episode of Extend, we’re tackling a crucial health issue: high blood pressure. Often called the "silent killer," high blood pressure increases your risk for heart attacks, strokes, kidney disease, and more. But what if you could prevent these risks before they escalate? I’ll break down why measuring your blood pressure at home is far mor…
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Ever feel stuck, even when you're doing all the right things? In this episode, Dr. Shah sits down with Dr. Alok Trivedi, also known as Dr. Rewire, to explore how our unresolved traumas, subconscious beliefs, and identity patterns silently shape our health, habits, and happiness. You’ll discover how trauma wires into the nervous system, why mindset …
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With shelves full of flashy promises, it’s time to cut through the noise. In this episode, Dr. Shah and Dr. Greg Kelly explore what science actually says about supplements—and what your body truly needs to perform at its best. You’ll learn how nootropics, adaptogens, and probiotics influence brain health, stress resilience, and longevity. Backed by…
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Inflammation drives nearly every chronic disease, yet most people overlook a key player in regulating it: the vagus nerve. This critical nerve connects brain to body, controlling digestion, heart rate, immunity, and recovery. But chronic stress shuts it down, leading to poor vagal tone, dysregulated inflammation, and reduced resilience. In this epi…
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Heart disease is still the number one cause of death, yet most people don’t realize how preventable it actually is. In this solo episode of Extend, I’m kicking off our new series on preventative medicine by breaking down the essential tests and metrics you need to know to protect your heart. I’ll walk you through the four key areas I evaluate in ev…
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Most people don’t think about their health until something goes wrong—but what if you could catch potential issues before they become a problem? Studies show that up to 70% of serious health conditions are preventable with early detection, yet traditional healthcare often focuses on treating symptoms rather than identifying root causes. Taking a pr…
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