Best Dwarkesh Patel Podcasts (2025)

1
Dwarkesh Patel: AI Continuous Improvement, Intelligence Explosion, Memory, Frontier Lab Competition 1:11:30

9d ago1:11:30

1:11:30

Dwarkesh Patel is the host of the Dwarkesh Podcast. He joins Big Technology Podcast to discuss the frontiers of AI research, sharing why his timeline for AGI is a bit longer than the most enthusiastic researchers. Tune in for a candid discussion of the limitations of current methods, why continuous AI improvement might help the technology reach AGI…

1
Godfather of Synthetic Bio on De-Aging, De-Extinction, & Weaponized Mirror Life — George Church 1:33:45

14h ago1:33:45

1:33:45

George Church is the godfather of modern synthetic biology and has been involved with basically every major biotech breakthrough in the last few decades. Professor Church thinks that these improvements (e.g., orders of magnitude decrease in sequencing & synthesis costs, precise gene editing tools like CRISPR, AlphaFold-type AIs, & the ability to co…

1
Is AI Actually Saving The Stock Market? — With Tom Lee 1:02:02

2d ago1:02:02

1:02:02

Tom Lee is the chief investment officer at Fundstrat Capital and head of research at FSInsight. He joins Big Technology Podcast to discuss whether generative AI wave is actually holding up the stock market and what would happen if it stalled or fell apart. We discuss what an AI 'Black Swan' event would look like, whether the bubble would pop, and w…

1
How to Be a Super Ager (with Eric Topol) 1:01:24

3d ago1:01:24

1:01:24

What if we could delay--or even prevent--Alzheimer's, cancer, and heart disease? What if much of what you know about aging is wrong? Listen as cardiologist and author Eric Topol of the Scripps Research Institute talks about his new book Super Agers with EconTalk's Russ Roberts. They discuss why your genes matter less than you think, how your immune…

1
An unfiltered conversation with Sahil Lavingia, CEO of Gumroad 1:08:31

6d ago1:08:31

1:08:31

Join Nolan Fortman and Logan Kilpatrick for a conversation about AI, the future of work, autonomous coding agents, and more with Sahil Lavingia, the CEO and founder of Gumroad & Antiwork. Sahil has been a builder for over 10 years, initially raising a small VC round then series A for Gumroad and is now building as an AI first product company. It wa…

1
OpenAI and Microsoft Tension Boils, Amazon’s Job Automation, Zuck’s Spending Spree 48:17

6d ago48:17

48:17

Ranjan Roy from Margins is back for our weekly discussion of the latest tech news. We cover: 1) OpenAI and Microsoft's tension boils as business relationship grows complex 2) Is Microsoft being anticompetitive? 3) How much money OpenAI owes Microsoft 4) Who holds the power in the relationship? 5) OpenAI discounts ChatGPT enterprise 6) New study sho…

1
Trump Is Selling a Phone + The Start-Up Trying to Automate Every Job + Allison Williams Talks ‘M3GAN 2.0’ 1:03:57

7d ago1:03:57

1:03:57

This week, President Trump’s family business announced that it was introducing a mobile phone and a cellular network. We tick through the many potential conflicts of interest this new business venture raises. Then, the co-founders of the startup Mechanize defend their efforts to automate away all jobs — starting with software engineering. And final…

1
China’s Manufacturing Dominance: State Directives & Ruthless Competition — Arthur Kroeber 2:26:43

8d ago2:26:43

2:26:43

Arthur Kroeber is a leading researcher on Chinese tech and macro, a founding partner at Gavekal Dragonomics, and author of "China's Economy: What Everyone Needs to Know." It's the most useful, detailed resource I've found of how China actually works. On this episode, we discuss how China achieved high-tech manufacturing dominance, and where they'll…

1
Leon Kass on the Wisdom of Rousseau 1:17:07

11d ago1:17:07

1:17:07

Does technology liberate us or enslave us? How do our social interactions affect our sense of self and our emotional health? Listen as author and master teacher Leon Kass and EconTalk's Russ Roberts do a close reading of a few paragraphs of Jean-Jacques Rousseau and explore some of the deepest aspects of our relationships with each other and with o…

1
Sam Altman’s Gentle Singularity, Zuck’s AI Power Play, Burning Of The Waymos 1:00:51

13d ago1:00:51

1:00:51

Ranjan Roy from Margins is back for our weekly discussion of the latest tech news. We cover: 1) Sam Altman's 'Gentle Singularity' essay 2) Is Altman overhyping the technology's current capabilities 3) Why the next few years may see crazy AI development 4) The case for and against humanoid robots 5) OpenAI's o3 pro model and the value of tool use 6)…

1
Meta Bets on Scale + Apple’s A.I. Struggles + Listeners on Job Automation 1:07:27

14d ago1:07:27

1:07:27

This week, Meta hits the reset button on A.I. But will a new research lab and a multibillion-dollar investment in Scale AI bring the company any closer to its stated goal of “superintelligence”? Then we break down Apple’s big developer conference, WWDC: What was announced, what was noticeably absent, and why Apple seems a little stuck in the past. …

1
“China’s digging out of a crisis. And America’s luck is wearing thin.” — Ken Rogoff 1:36:04

15d ago1:36:04

1:36:04

Ken Rogoff is the former chief economist of the IMF, a professor of Economics at Harvard, and author of the newly released Our Dollar, Your Problem and This Time is Different. On this episode, Ken predicts that, within the next decade, the US will have a debt-induced inflation crisis, but not a Japan-type financial crisis (the latter is much worse,…

1
What Apple's Failures Say About AI's Limitations — With M.G. Siegler 56:44

16d ago56:44

56:44

M.G. Siegler is the author of Spyglass. He joins Big Technology to discuss Apple’s subdued WWDC and whether it signals deeper trouble with AI's capabilities. Tune in to hear a breakdown of Apple’s “UI over AI” approach, whether the company can pull off the Apple Intelligence vision at all, and if Liquid Glass is a redesign destined to fail. We also…

1
WWDC Dispatch: Apple Refines in a Reinvention Era 13:14

17d ago13:14

13:14

Alex Kantrowitz joins live from WWDC, where Apple just announced a number of new design changes including a completely updated operating system with 'Liquid Glass' styling. But in an era of reinvention, where AI is at the center of the technology's evolution, Apple introduced a number of refinements. This short, solo episode looks at Apple's strate…

1
Two Cheers for Libertarianism and Econ 101 (with Noah Smith) 1:22:06

18d ago1:22:06

1:22:06

Economist Noah Smith was so focused on libertarianism's theoretical flaws, he overlooked its political importance. Trump's tariff policy opened his eyes and made him re-assess the virtues of both libertarianism and Econ 101. Listen as he and EconTalk's Russ Roberts explore the way political competition has shaped economic policy in surprising ways …

1
Apple’s AI 'Gap Year' at WWDC?, Elon Vs. Trump Goes Nuclear, NYTimes’ OpenAI Attack 1:01:33

20d ago1:01:33

1:01:33

Ranjan Roy from Margins is back for our weekly discussion of the latest tech news. We cover: 1) What's coming at Apple's WWDC developer conference 2) Apple may be taking an AI gap year 3) Apple's Upcoming AI bets 4) Airpods enhancements 5) Apple's new operating system 6) Why Apple should buy Perplexity 7) Is Perplexity positioning itself for a sale…

1
The Trump-Musk Fallout + A DOGE Coder Speaks + ChefGPT 1:06:58

21d ago1:06:58

1:06:58

This week, Kevin and Casey discuss the sudden breakdown between President Trump and Elon Musk, whose disagreements over the policy bill before Congress quickly erupted into an all-out feud. Then, an ex-DOGE coder explains what it was really like to work inside the Trump administration’s cost-cutting arm. And finally, the former New York Times resta…

1
Anthony Scaramucci: Elon Musk’s Trump Exit, Tim Cook’s Tariff Problem 1:04:06

23d ago1:04:06

1:04:06

Anthony Scaramucci is the founder and managing partner at SkyBridge Capital, and host of The Rest Is Politics US. Scaramucci joins Big Technology Podcast to talk about his brief experience as Trump's communication director, what derailed Elon Musk’s White House stint, the problems with Trump’s 'Big Beautiful Bill,' the state of the trade war, Tim C…

1
An unfiltered conversation with Anjney Midha, General Partner at A16Z 58:28

25d ago58:28

58:28

Join Nolan Fortman and Logan Kilpatrick as they sit down with legendary investor and builder Anjney Midha to chat all things AI. From foundation model progress, to evals, to how to find the next generation of AI enabled products, Anjney shares his deep insights around AI as one of the critical figures in the ecosystem.…

1
EconTalk #1000 (with Russ Roberts) 1:08:49

25d ago1:08:49

1:08:49

In honor of EconTalk's 1,000th episode, host Russ Roberts reflects on his long, strange journey from pioneer of the podcast format to weekly interviewer of leading economists, authors, and thinkers. Hear him answer your--and Chat GPT's--questions about why he got started, how he preps, and how he picks guests. He also explains why debate gave way t…

1
Mass AI-Driven Unemployment, NVIDIA Surges, CEOs' AI Avatars Unleashed 51:53

27d ago51:53

51:53

Ranjan Roy from Margins is back for our weekly discussion of the latest tech news. We cover: 1) Anthropic CEO Dario Amodei's prophesy that 50% of entry level work will disappear 2) Hype or true: Is mass AI-driven unemployment just marketing? 3) How Amodei's prediction could come true 4) How work might shift even before job loss, as in the case of A…

1
The A.I. Jobpocalypse + Building at Anthropic with Mike Krieger + Hard Fork Crimes Division 1:08:02

28d ago1:08:02

1:08:02

This week, we dive into Kevin’s recent column about how A.I. is affecting the job market for new graduates, and debate whether the job apocalypse is already here for entry-level work. Then Mike Krieger joins us to discuss the new Claude 4 model, the future of work and the online chatter over whether an A.I. system could blackmail you. And finally, …

1
Xi Jinping’s paranoid approach to AGI, debt crisis, & Politburo politics — Victor Shih 1:29:09

29d ago1:29:09

1:29:09

On this episode, I chat with Victor Shih about all things China. We discuss China’s massive local debt crisis, the CCP’s views on AI, what happens after Xi, and more. Victor Shih is an expert on the Chinese political system, as well as their banking and fiscal policies, and he has amassed more biographical data on the Chinese elite than anyone else…

1
She Wants AI To Help You Thrive, Not Just Keep You Company — Y-Lan Boureau 1:04:05

30d ago1:04:05

1:04:05

Y-Lan Boureau is the founder & CEO of ThrivePal, an OpenAI-funded AI startup, and a former Meta AI researcher. Boureau joins Big Technology Podcast to discuss why the next frontier for AI should be science‑backed coaching that nudges us toward healthier habits and deeper real‑world relationships. Tune in to hear how large‑language models can push u…

1
Nature vs. Nurture (with Paul Bloom) 1:07:44

1M ago1:07:44

1:07:44

How much of our success or failure is written in our genes? How much is under our control? Is it nature or nurture or is that dichotomy too simplistic? Hear EconTalk's Russ Roberts and psychologist Paul Bloom discuss why the nature vs. nurture question is actually worth taking seriously and how by understanding it we can help ourselves and others.…

1
OpenAI's Jony Ive Moment, Anthropic's Big New Model, Google Enters 'AI Mode' 50:58

1M ago50:58

50:58

Ranjan Roy from Margins is back for our weekly discussion of the latest tech news. We cover: 1) Alex's unexpected Sergey Brin interview 2) Jony Ive sells his IO device company to OpenAI 3) What this device could be 4) Is Jony + Sam bad for Apple? 5) Could this device work? 6) What the move to ambient assistants could signal for tech 7) Anthropic's …

1
Google DeepMind C.E.O. Demis Hassabis on Living in an A.I. Future 1:13:42

1M ago1:13:42

1:13:42

This week, we take a field trip to Google and report back about everything the company announced at its biggest show of the year, Google I/O. Then, we sit down with Google DeepMind’s chief executive and co-founder, Demis Hassabis, to discuss what his A.I. lab is building, the future of education, and what life could look like in 2030. Guest: Demis …

1
How Does Claude 4 Think? — Sholto Douglas & Trenton Bricken 2:24:01

1M ago2:24:01

2:24:01

New episode with my good friends Sholto Douglas & Trenton Bricken. Sholto focuses on scaling RL and Trenton researches mechanistic interpretability, both at Anthropic. We talk through what’s changed in the last year of AI research; the new RL regime and how far it can scale; how to trace a model’s thoughts; and how countries, workers, and students …

1
The stakes of AI moral status 37:29

1M ago37:29

37:29

On seeing and not seeing souls. Text version here: https://joecarlsmith.com/2025/05/21/the-stakes-of-ai-moral-status/By Joe Carlsmith

1
Google DeepMind CEO Demis Hassabis + Google Co-Founder Sergey Brin: Scaling AI, AGI Timeline, Simulation Theory 30:47

1M ago30:47

30:47

Demis Hassabis is the CEO of Google DeepMind. Sergey Brin is the co-founder of Google. The two leading tech executives join Alex Kantrowitz for a live interview at Google's IO developer conference to discuss the frontiers of AI research. Tune in to hear their perspective on whether scaling is tapped out, how reasoning techniques have performed, wha…

Podcasts Worth a Listen

Dwarkesh Patel Podcasts

Podcasts Worth a Listen

Quick Reference Guide