Best Mrc Ctu At Ucl Trial Talk Podcast Podcasts (2025)

1
International Clinical Trials Methodology Conference 2024 roundup - early careers edition 25:09

7M ago25:09

25:09

At the start of October, lots of the Unit’s clinical trials methodology researchers travelled to Edinburgh, for the 7th International Clinical Trials Methodology Conference (ICTMC).ICTMC is the largest academic-led conference on clinical trials, bringing together trialists from across the globe to present their latest work in trials methodology. Th…

1
Lessons from UKCTOCS, a large-scale trial in ovarian cancer screening 26:57

1+ y ago26:57

26:57

UKCTOCS (UK Collaborative Trial of Ovarian Cancer Screening) is one of the largest screening trials in ovarian cancer. More than 200,000 women from England, Wales and Northern Ireland took part in it, and it ran for almost two decades. Designing and running such a large and lengthy trial came with its own challenges. In this episode, Professor Usha…

1
Careers in TB trials with Andrew Nunn and Sarah Meredith 28:56

1+ y ago28:56

28:56

In the first episode of our new Trial Talk series, Hanif Esmail and Conor Tweed take over the microphones to interview Andrew Nunn and Sarah Meredith, who have both recently retired from the Unit, having spent a combined total of 92 years working in the field of tuberculosis (TB). As we celebrate Andrew and Sarah’s long and accomplished careers, we…

1
World AIDS Day (part 2): Bringing hope through research to young people living with HIV 19:01

1+ y ago19:01

19:01

Every year on 1st December, we mark World AIDS Day to show solidarity in the fight against HIV and AIDS, and to remember those who have sadly lost their lives. Since the start of the global AIDS epidemic in the 1980s, researchers have made enormous progress towards preventing HIV transmission, and treating those who are living with HIV so that the …

1
World AIDS Day (part 1): Closing the gap between adults and children 24:04

1+ y ago24:04

24:04

Every year on 1st December, we mark World AIDS Day to show solidarity in the fight against HIV and AIDS, and to remember those who have sadly lost their lives. Since the start of the global AIDS epidemic in the 1980s, researchers have made enormous progress towards preventing HIV transmission, and treating those who are living with HIV so that the …

1
Octopus (part 4): Involvement of people affected by MS with Susan Scott 20:02

1+ y ago20:02

20:02

Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS), which is designed and run by the MRC Clinical Trials Unit at UCL. Thanks to its multi-arm multi-stage platform design, Octopus has the potential to transform the way treatments for progressive MS are tested. The trial is now open in the UK and will be recrui…

1
Octopus (part 3): The patients’ experience with Dawn Lyle and Matthew Justin 24:04

1+ y ago24:04

24:04

Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS), which is designed and run by the MRC Clinical Trials Unit at UCL. Thanks to its multi-arm multi-stage platform design, Octopus has the potential to transform the way treatments for progressive MS are tested. The trial is now open in the UK and will be recrui…

1
Octopus (part 2): Introducing the trial with Jeremy Chataway 24:10

1+ y ago24:10

24:10

Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS), which is designed and run by the MRC Clinical Trials Unit at UCL. Thanks to its multi-arm multi-stage platform design, Octopus has the potential to transform the way treatments for progressive MS are tested. The trial is now open in the UK and will be recrui…

1
Octopus (part 1): The MS landscape with Jeremy Chataway, Dawn Lyle and Matthew Justin 17:20

1+ y ago17:20

17:20

Octopus is a new clinical trial for people living with progressive multiple sclerosis (MS), which is designed and run by the MRC CTU at UCL. Thanks to its multi-arm multi-stage platform design, Octopus has the potential to transform the way treatments for progressive MS are tested. The trial is now open in the UK and will be recruiting participants…

1
Optimising treatments with the new MAMS-ROCI design 24:28

1+ y ago24:28

24:28

Innovative platform designs present an opportunity to run faster and more efficient clinical trials. Clinical trials methodology is a research area that looks at how to improve the design, conduct, and analysis of clinical trials. It focuses on developing and implementing new methods to help run trials faster and more efficiently, that will ultimat…

1
STAMPEDE (part 3): Impact and legacy with Max Parmar & Nick James 23:23

1+ y ago23:23

23:23

STAMPEDE is a long-running trial in advanced prostate cancer, in which nearly 12,000 men have taken part. Thanks to its multi-arm multi-stage platform design, STAMPEDE has tested many different treatments and directly led to improvements in the standard of prostate cancer care several times. This Trial Talk podcast mini-series will explore the tria…

1
STAMPEDE (part 2): The role of the patient voice with David Matheson, Max Parmar & Nick James 18:00

2y ago18:00

18:00

STAMPEDE is a long-running trial in advanced prostate cancer, in which nearly 12,000 men have taken part. Thanks to its multi-arm multi-stage platform design, STAMPEDE has tested many different treatments and directly led to improvements in the standard of prostate cancer care several times. This Trial Talk podcast mini-series will explore the tria…

1
STAMPEDE (part 1): A new era for prostate cancer research with Max Parmar & Nick James 18:03

2y ago18:03

18:03

STAMPEDE is a long-running trial in advanced prostate cancer, in which nearly 12,000 men have taken part. Thanks to its multi-arm multi-stage platform design, STAMPEDE has tested many different treatments and directly led to improvements in the standard of prostate cancer care several times. This Trial Talk podcast mini-series will explore the tria…

1
The REFINE trial: How can we improve the way we give cancer immunotherapy? 16:57

2y ago16:57

16:57

Immunotherapy drugs fight cancer by helping the immune system recognise and attack cancer cells. These drugs have revolutionised cancer treatment over the last decade, improving survival for many people with different types of cancer. However, researchers are still unsure of the best way to give immunotherapy, which can come with unpredictable side…

1
How can clinical trials make the most of healthcare systems data? 25:39

2y ago25:39

25:39

Running a clinical trial means collecting a lot of data from the trial participants. But some of this data might be collected and stored in healthcare systems, as well as in clinical trial case report forms. What if we could avoid this doubling up, save time and resources, improve recruitment and reduce missing data? In this episode we explore the …

1
Neonatal infections (part 2): How the NeoSep1 trial will help treat sick newborns 21:13

2y ago21:13

21:13

Neonatal sepsis is a life-threatening infection that affects up to 3 million babies per year globally. In an effort to identify better treatments, the NeoSep1 clinical trial evaluates new antibiotic combinations for newborn babies with sepsis. To learn more about the trial, we speak to Adrie Bekker and Cristina Obiero, principal investigators of th…

1
Neonatal infections (part 1): The NeoOBS study and the global challenge of neonatal sepsis 23:52

2y ago23:52

23:52

214,000 newborn babies die of sepsis caused by infections that are resistant to antibiotics every year. This is a major problem worldwide, but disproportionally affects low- and middle- income countries.Reenu Thomas and Adrie Bekker, two neonatologists from South Africa, and Francesca Schiavone, clinical project manager at the MRC CTU at UCL in Lon…

1
The STREAM2 trial: How should we treat multi-drug resistant tuberculosis? 19:59

2y ago19:59

19:59

For World TB Day, this episode explores the global burden of tuberculosis (TB) and how growing antibiotic resistance can complicate treatment options. Andrew Nunn, a Professor of Epidemiology, discusses his work on the STREAM2 trial, which investigated how treatment for multi-drug resistant TB could be shortened and made more acceptable for patient…

1
Ovarian cancer screening: The results of the UKCTOCS trial 17:10

4y ago17:10

17:10

Around 4000 women die of ovarian cancer in the UK each year. It is often diagnosed at an advanced stage, making treatment difficult. The UK Collaborative Trial of Ovarian Cancer Screening, known as the UKCTOCS trial, followed up more than 200,000 women over an average of 16 years, in an effort to improve diagnosis of ovarian cancer. This podcast ep…

1
Andrew Nunn talks medical statistics, TB, and Algerian nomads (Part 2) 35:05

6+ y ago35:05

35:05

Andrew Nunn joined the MRC’s Tuberculosis & Chest Diseases Unit as a statistician in 1966. During the next 20 years he was directly involved in the design, conduct and analysis of the programme of trials conducted under the leadership of Professors Wallace Fox and Denny Mitchison in East Africa, Hong Kong and Singapore which led to the worldwide ad…

1
Andrew Nunn talks medical statistics, TB, and Algerian nomads (Part 1) 31:40

6+ y ago31:40

31:40

Andrew Nunn joined the MRC’s Tuberculosis & Chest Diseases Unit as a statistician in 1966. During the next 20 years he was directly involved in the design, conduct and analysis of the programme of trials conducted under the leadership of Professors Wallace Fox and Denny Mitchison in East Africa, Hong Kong and Singapore which led to the worldwide ad…

1
Jayne Tierney talks systematic reviews, impact, and fish parasites 30:46

7y ago30:46

30:46

Jayne Tierney has been a Research Scientist at the Unit since it was formed in 1999, and prior to that, in the Cancer Trials Office in Cambridge. For more than 20 years, she has been responsible for designing and conducting systematic reviews and meta-analyses to rigorously re-evaluate the effectiveness of therapies; projects that have influenced p…

1
ARREST: Rifampicin for Staph. aureus bacteraemia (full length) 20:20

7+ y ago20:20

20:20

Staphylococcus aureus (S. aureus) bacteraemia is a common infection worldwide, with mortality rates of around 20%, but little research has been done on how best to treat it. This episode explores the results of the ARREST trial, which looked at adding rifampicin to standard antistaphylococcal antibiotic treatment.…

1
ARREST: Rifampicin for Staph. aureus bacteraemia (short version) 10:10

7+ y ago10:10

10:10

Staphylococcus aureus (S. aureus) bacteraemia is a common infection worldwide, with mortality rates of around 20%, but little research has been done on how best to treat it. This episode explores the results of the ARREST trial, which looked at adding rifampicin to standard antistaphylococcal antibiotic treatment. This is the short version of the r…

1
Patrick Royston receives the Stata Journal Editors' Prize 2016 31:25

7+ y ago31:25

31:25

Back in January 2017, Professor Patrick Royston was awarded the Stata Journal Editors’ Prize 2016, for his significant contributions to Stata and the Stata community over the last 25 years, and for three papers he published in the Stata Journal during the previous two years. Today, Patrick will officially receive his award at 2017 London Stata User…

Podcasts Worth a Listen

Mrc Ctu At Ucl Trial Talk Podcast

Podcasts Worth a Listen

1
MRC CTU Podcasts

MRC Clinical Trials Unit at UCL

1
International Clinical Trials Methodology Conference 2024 roundup - early careers edition 25:09

1
Lessons from UKCTOCS, a large-scale trial in ovarian cancer screening 26:57

1
Careers in TB trials with Andrew Nunn and Sarah Meredith 28:56

1
World AIDS Day (part 2): Bringing hope through research to young people living with HIV 19:01

1
World AIDS Day (part 1): Closing the gap between adults and children 24:04

1
Octopus (part 4): Involvement of people affected by MS with Susan Scott 20:02

1
Octopus (part 3): The patients’ experience with Dawn Lyle and Matthew Justin 24:04

1
Octopus (part 2): Introducing the trial with Jeremy Chataway 24:10

1
Octopus (part 1): The MS landscape with Jeremy Chataway, Dawn Lyle and Matthew Justin 17:20

1
Optimising treatments with the new MAMS-ROCI design 24:28

1
STAMPEDE (part 3): Impact and legacy with Max Parmar & Nick James 23:23

1
STAMPEDE (part 2): The role of the patient voice with David Matheson, Max Parmar & Nick James 18:00

1
STAMPEDE (part 1): A new era for prostate cancer research with Max Parmar & Nick James 18:03

1
The REFINE trial: How can we improve the way we give cancer immunotherapy? 16:57

1
How can clinical trials make the most of healthcare systems data? 25:39

1
Neonatal infections (part 2): How the NeoSep1 trial will help treat sick newborns 21:13

1
Neonatal infections (part 1): The NeoOBS study and the global challenge of neonatal sepsis 23:52

1
The STREAM2 trial: How should we treat multi-drug resistant tuberculosis? 19:59

1
Ovarian cancer screening: The results of the UKCTOCS trial 17:10

1
Andrew Nunn talks medical statistics, TB, and Algerian nomads (Part 2) 35:05

1
Andrew Nunn talks medical statistics, TB, and Algerian nomads (Part 1) 31:40

1
Jayne Tierney talks systematic reviews, impact, and fish parasites 30:46

1
ARREST: Rifampicin for Staph. aureus bacteraemia (full length) 20:20

1
ARREST: Rifampicin for Staph. aureus bacteraemia (short version) 10:10

1
Patrick Royston receives the Stata Journal Editors' Prize 2016 31:25

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