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Infectious Dose

Infectious Dose

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Infectious dose is the shot of science you need to protect yourself from misinformation. Heather McSharry, PhD, an expert in viral pathogenesis, brings her blog to the airwaves to help bridge the dangerous gap between the science of infectious diseases and public misperception. On the podcast website, infectiousdose.com, all episodes have corresponding blog posts with the information contained in the episode along with links or PDFs for all sources used. To prevent unwelcome surprises, episo ...
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What if our biggest mistake in vaccine communication wasn’t misinformation—but misexpectation? In this episode of Infectious Dose, Heather digs into the seductive myth of sterilizing immunity—the idea that a “perfect” vaccine blocks infection completely—and explores how this scientific fable has distorted public expectations, undermined trust, and …
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In this episode, Heather delves into the story of Sin Nombre virus and the disease it causes, Hantavirus Pulmonary Syndrome. From its rodent origins and rapid progression to the public health response and scientific breakthroughs that followed, we explore how a rare virus rewrote the rules of infectious disease in North America—and why it remains a…
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Heather gives updates on 2025 measles outbreaks in every region of the world and discusses global efforts to curb them. She also debunks the deadly lies about measles from RFK Jr. in her fan favorite segment WTF-RFK! and answers listener questions in her new segment Hot Zone Hotline. Explicit rating is for mild and limited profanity because, I mean…
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Invasive meningococcal disease strikes fast—and often without warning—especially in close-contact environments like college dorms and military barracks. While it’s rare, the consequences can be devastating: death within hours, or lifelong complications like limb loss and brain damage. In this episode Heather explains all about how Neisseria meningi…
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In the 5th episode in her vaccine safety series, Heather gives straightforward, science-based answers to some of the most common questions about what’s in vaccines including an in-depth look at what's in several specific vaccines and the truth debunking false claims you've seen recently in the media.…
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Anthrax is one of the oldest infectious diseases known to science. Its ability to survive harsh environments and reemerge as a deadly pathogen centuries later is a biological marvel—and a global health concern. Heather covers all you want to know about anthrax from its formidable spore structure and use as a bioweapon, to its recent outbreaks and p…
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In the second vaccine safety episode, Heather describes how Andrew Wakefield's fraudulent science cost the world the elimination of measles and hurt children. With evidence to back it up, she goes into detail on what he did and how he still manipulates parents fears to make money. Marked explicit for limited and mild profanity.…
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This is the original Pathogen Perspectives episode rebranded for Infectious Dose, originally published in 2020. Heather provides an in-depth discussion on the COVID-19 vaccine platforms other than mRNA, that were in clinical trials around the world. These include self-replicating mRNA, DNA, Protein-based, Attenuated virus, Inactivated virus, Repurp…
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This is the original Pathogen Perspectives Episode published in 2020, rebranded for Infectious Dose. Heather provides an in-depth discussion on the COVID-19 mRNA vaccines authorized for emergency use in the US. She covers: · What is mRNA · How mRNA vaccines work · How we know they are safe · Why they cannot change your DNA · How long might immunity…
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