Best Sam Kamani Podcasts (2025)

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278: Scaling Trust in Web3 — Bruno Maia on Cartesi’s Verifiable Rollup Infrastructure 43:24

20h ago43:24

43:24

In this episode of Web3 with Sam Kamani, Bruno Maia, Head of Growth at Cartesi, shares his journey from telecom to Web3, his early ICO days, and how he joined Cartesi to help expand Ethereum’s design space with verifiable computation. Cartesi is building a Stage 2 optimistic rollup infrastructure with a fully verifiable Linux-based VM, enabling dev…

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277: Why Web3 Needs AI Agents That Remember — Jan on OpenMind’s Vision 46:24

4d ago46:24

46:24

Jan, founder of OpenMind, joins Sam to discuss how they're building a memory layer for AI agents in Web3. They cover the limitations of stateless agents, OpenMind’s modular memory architecture, and how developers can build “smart, sovereign agents” that persist across time, dApps, and chains. Jan also shares insights on use cases across DeFi, NFTs,…

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276: Building GOAT Gaming: Web3 Gaming, Amy the AI Agent & Retention on Telegram 25:29

7d ago25:29

25:29

Simon Davis, founder of GOAT Gaming and Mighty Bear Games, joins Sam to unpack how they’re using Telegram, AI agents, and meme culture to scale Web3-native games. He breaks down their AI-powered assistant “Amy,” the technical challenges of building engaging agents, and how GOAT reached 6M+ users with Telegram-first distribution. They also discuss p…

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275: From TikTok to Binance: James on Gen Z, Bitcoin ATHs & the Future of Crypto 37:41

10d ago37:41

37:41

James Quinn Kumar from Binance ANZ joins Sam to explore how Binance reached over 280 million users in just 8 years. He shares the lessons from Facebook and TikTok that helped Binance thrive in B2C, the role of liquidity in institutional adoption, and how Gen Z sees Bitcoin as a new path to wealth in a world of rising property prices. They also dive…

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274: Scaling Bitcoin DeFi — Charlie on Bitlayer, BTR launch & unlocking $1T in liquidity 33:17

13d ago33:17

33:17

In this episode, Charlie, co-founder of Bitlayer, shares how they are building a Bitcoin rollup and trust-minimized BVM bridge to unlock BTC liquidity for DeFi while maintaining Bitcoin-level security. Backed by Franklin Templeton and top mining pools like F2Pool, Bitlayer is enabling yield-bearing BTC (YBTC), partnerships with Sui and Solana, and …

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273: AI agents need open money — Matthew Graham on Ryze Labs, crypto rails & emerging markets 32:31

14d ago32:31

32:31

What happens when an emerging‑markets banker, lifelong Reddit degen, and early Ethereum believer builds a global crypto fund focused on AI? Meet Matthew “Matty” Graham, Managing Partner at Ryze Labs. Matty shares how a pizza post pulled him into Bitcoin, why the Ethereum whitepaper was his “drop everything” moment, and how Ryze helps founders reach…

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272: Privacy on demand — Shahaf on COTI’s quest to make blockchains confidential 30:52

21d ago30:52

30:52

In this episode, COTI Network CEO Shahaf Bar-Geffen joins Sam to unpack why privacy + scalability are the two missing pillars holding crypto back from mass, institutional adoption. Shahaf recounts COTI’s journey from 2017 payment rails to today’s garbled-circuit EVM, explains “privacy on demand” for any chain, and reveals how AI trading agents and …

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271: Driving Web3 Forward — Evan Kuhn on How DeLorean is Bringing Cars On-Chain 27:00

26d ago27:00

27:00

Evan Kuhn, President of DeLorean Labs, joins Sam to share how the iconic car brand is entering Web3. From on-chain car reservations and data-powered utility to the launch of the DMC token and partnerships with stars like Patrick Stewart and Christopher Lloyd — DeLorean is building much more than nostalgia. They discuss how the Flux Protocol enables…

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270: From Google Employee to DePIN: Alex on Scaling NodeOps to Tens of Millions in Revenue 26:36

27d ago26:36

26:36

Alex from NodeOps joins Sam to share how they’re building a decentralized infrastructure platform that’s already generating millions in revenue. She discusses her background at Google and other Web3 infra giants, NodeOps’ unique AI-powered tools, dynamic mint-and-burn tokenomics, and how they’re shaping the future of DePIN. From staking to Security…

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269: Building Trust in Legal Tech — How Legalise Is Redefining AI for SaaS Contracts 27:29

1M ago27:29

27:29

Usman Wahid, a 23-year veteran lawyer and now founder of Legalise, joins Sam Kamani to explore the evolution of AI in the legal world. They dive into hallucinations in legal AI, how Legalise enables smarter contract negotiation for SaaS companies, the tension between centralized vs decentralized AI models, and how the legal profession must adapt. U…

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268: Building Regulated Crypto Infrastructure in Europe with Vadim Rozov from Simplify Labs 22:34

1M ago22:34

22:34

Vadym Rozov, founder of Simplify Labs, joins the podcast to break down the regulatory future of crypto in Europe. With MiCA and DORA reshaping the landscape, Simplify Labs is helping exchanges stay compliant and launch fast with modular white-label solutions. Vadym shares what sets their platform apart, the challenges of MiCA implementation, how ba…

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267: From Black Box to Transparent AI: 0G.AI’s Vision for Decentralized Compute & Storage 26:37

1M ago26:37

26:37

Michael from 0G.AI joins Sam to discuss how they're building the AI operating system of the decentralized world. From decentralized compute and high-throughput storage to local consensus clusters and alignment networks, 0G is tackling the hardest infrastructure challenges at the intersection of AI and blockchain. With over 10 million wallets, 500+ …

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266: The Smartest Wallet Yet? Rishi from Tychi on AI, UGF & Full-Stack Web3 UX 29:28

2M ago29:28

29:28

What if your wallet could pay gas fees on any chain—using just BNB? In this episode, Sam Kamani speaks with founder Rishi, Yashi and Divyansh from Tychi Wallet about building a next-gen smart wallet with AI, on-chain privacy, and a universal gas framework (UGF) that simplifies multi-chain interactions. They discuss how Tychi aims to replace clunky …

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254: Web3 Data Survivability – Robert Mofrad on Serenity’s Approach to Inheritance, Identity & Biometric Security 36:13

2M ago36:13

36:13

Robert Mofrad from Serenity joins the show to talk about digital asset inheritance, decentralized data survivability, and the power of biometrics in Web3. From seed phrase backups to biometric cards that double as wallets, Serenity is tackling the often-overlooked infrastructure needed for long-term Web3 adoption. Robert also shares his thoughts on…

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265: Tokenizing Oil as a Security — Dave from OilXCoin on Regulated RWAs in Web3 35:33

2M ago35:33

35:33

What if your entry point to crypto wasn’t Bitcoin or ETH… but a Real World Asset backed token tied to real oil production? In this episode, Dave from OilXCoin shares how their team is bridging the gap between traditional energy markets and Web3 by launching a token which has received regulatory approval. From upstream oil leases and production logi…

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264: From Bloomberg to Blockchain — Sergio’s Mission to Power Web3 with Reliable Data 34:23

2M ago34:23

34:23

What’s holding back enterprise adoption of blockchain? In this episode, Sergio from Sonar X joins Sam to explain why the missing piece is data infrastructure. Drawing from experience at Bloomberg and AWS (where he led Amazon Managed Blockchain), Sergio breaks down why most blockchain systems are broken at the data layer—and how Sonar X is building …

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263: From Police Officer to Web3 Builder — Rong Kai’s Journey with Reactive Network 44:04

2M ago44:04

44:04

What if smart contracts could see and react to events across multiple blockchains—automatically? In this episode, I speak with Rong Kai, co-founder of Reactive Network, a groundbreaking Layer 0.5 protocol designed to enable reactive smart contracts that operate fully on-chain. If you're a developer, founder, or anyone interested in the future of co…

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262: Farmsent’s Vision: How Sim Khela Is Using Web3 to Disrupt Global Agriculture and Feed More Kids 29:03

2M ago29:03

29:03

Sim Khela from Farmsent joins Sam to explore how blockchain, sensors, and co-ops are creating a new agricultural economy. From decentralized food marketplaces to tokenized trade finance and carbon credits, Sim breaks down how Web3 can uplift farmers, ensure food security, and transform supply chains globally. With 160,000 farmers onboarded, partner…

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261: From Swiss Banking to Blockchain: Michele Crivelli on RWA Tokenization via NexBridge 25:39

2M ago25:39

25:39

What does it take to bring regulated, yield-bearing assets like U.S. Treasuries on-chain? Michele Crivelli, co-founder of NexBridge, shares how they're solving financial inclusion through tokenization of RWAs on the Liquid Network. From regulatory approvals in El Salvador to plans for tokenized equities and discretionary mandates, Michele breaks do…

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260: Interoperability for Every Chain: Jon Kol from Hyperlane on Building Seamless Cross-Chain Communication 38:52

2M ago38:52

38:52

Jon Kol, founder of Hyperlane, joins Sam Kamani to dive deep into one of crypto’s biggest challenges—interoperability. From his days at Morgan Stanley to building Hyperlane, Jon shares how they’re enabling any chain to communicate with any other through permissionless, modular frameworks. He explains why monolithic architectures can’t scale, how mo…

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259: Market Making Mastery: Martins from Gravity Team on Trading, Liquidity, and Web3 Investments 27:47

2M ago27:47

27:47

Martins from Gravity Team joins Sam to discuss the evolution of market making in Web3. Starting as a prop trading desk in 2017, Gravity now trades 1% of all spot crypto volume, provides liquidity to token projects, and invests in Web3 infrastructure. Martins explains what founders should look for in a market maker, why stablecoins and payments are …

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258: Inside MultiversX: Building the World’s Fastest Blockchain with Lucian 39:05

2M ago39:05

39:05

Lucian from MultiversX (formerly Elrond) joins Sam Kamani to break down how they’re building one of the fastest L1 blockchains in the world. From sharding to Supernova, discover how MultiversX is tackling decentralization, scalability, and real-world adoption with a new wave of architecture, global partnerships, and government use cases. Lucian als…

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257: Rebuilding Banking from the Ground Up — Maksym on WeFi’s Decentralized Mission 19:15

3M ago19:15

19:15

In this episode, I speak with Maksym, founder of WeFi, about his mission to create a fully decentralized alternative to traditional and neobanks. We dive into his origin story, the architecture of WeFi, how it abstracts complex DeFi systems for everyday users, and why millions of unbanked users are the real opportunity. Maksym also shares insights …

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256: Reinventing Stablecoins: Bundeep Singh on Pi Protocol, Tokenized Treasuries & Decentralized Yield 17:04

3M ago17:04

17:04

In this episode, Sam Kamani talks with Bundeep Singh Ranga, co-founder of Pi Protocol, about a new model for stablecoins. Bundeep shares how Pi separates principal and interest using tokenized US treasuries, empowering anyone to become a stablecoin minter and earn yield—without giving up liquidity. We explore why stablecoins are just getting starte…

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255: Why Build Another L1? Paul from Somnia on Somnia Protocol’s High-Throughput Blockchain 29:33

3M ago29:33

29:33

Paul, co-founder of Somnia Protocol and former Improbable exec, joins Sam Kamani to unpack why we still need new Layer 1s—and how Somnia’s high-performance, EVM-compatible blockchain is designed for mass-scale gaming, AI agents, and prediction markets. From his time at Goldman Sachs to building billion-dollar startups, Paul shares deep technical in…

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253: Polyhedra’s Eric on Scaling Secure AI with ZK Proofs and Real-Time ML Verification 28:49

3M ago28:49

28:49

Eric from Polyhedra joins Sam Kamani to unpack how zero-knowledge proofs are redefining interoperability, AI verification, and developer tooling. They dive into the launch of ZK PyTorch, EXP Chain, and how verifiable AI could become the new standard for trusted machine learning. If you’re building with LLMs, exploring trustless infrastructure, or c…

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252: How Sapien is Empowering the AI Gig Economy with Blockchain and Real Rewards, with Ben Noble from Sapien 40:36

3M ago40:36

40:36

How do you power the next generation of AI — without centralized data monopolies? In this episode, I talk with Ben Noble, Marketing Director at Sapien, about how Sapien is building the world’s first decentralized data foundry — rewarding people for training AI and contributing real-world data. We cover: How Sapien is combining Web3 incentives with …

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251: From Bots to Breakthroughs — Bandit Network’s Plan to Reinvent Web3 Growth 27:06

3M ago27:06

27:06

How do you grow a Web3 startup without falling into the same old traps — airdrops, bots, and unsustainable hype? In this episode, I speak with Sandesh, founder of Bandit Network, who shares how they’re building growth infrastructure for Web3 — combining off-chain and on-chain data, enabling sustainable campaigns, and even launching their own rollup…

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250: Meme Coins with a Mission: Neiro’s Journey from Rug Pull to Global Community 42:27

3M ago42:27

42:27

What happens when a meme coin gets rugged—and the community takes over? In this episode, Sam chats with S from Neiro, the community takeover lead, to explore the real mechanics behind meme coin takeovers, the evolution of the Neiro project, and how it became the spiritual successor to Dogecoin. From Vitalik-backed donations to exclusive IP licensin…

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249: Building Web3’s First Gaming Franchise: Frank Cheng on Apeiron, DoodiPals & Beyond 39:24

4M ago39:24

39:24

Frank Cheng, founder of Apeiron and DoodiPals, joins Sam to unpack four years of building in Web3 gaming. From raising three funding rounds to building an entire gaming franchise, Frank shares practical lessons on tokenomics, community building, and how to retain real players. Learn why most Web3 games fail and how to fix them, what role AI will pl…

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248: From Wall Street to Web3 Agents: Yang Tang on the Future of Autonomous AI 48:20

4M ago48:20

48:20

Yang Tang, co-founder of Memetica, joins Sam to dive deep into the world of AI agents — what they are, how they’re trained, and how they’re already generating value across Web2 and Web3. From his background in institutional finance and machine learning to launching BSD and Liam, Yang walks us through building intelligent, monetizable agents and why…

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247: Why Quantum-Ready and Bridgeless Tech is the Future: Kevin on Building Layer 1X 39:13

4M ago39:13

39:13

Kevin from Layer 1X joins Sam Kamani to discuss how they’re building a quantum-resistant, bridgeless blockchain that enables secure cross-chain swaps, multi-chain token issuance, and zero-gas fee transactions. Kevin also shares insights from his PhD in blockchain and quantum computing, and why he believes most of Web3 is unprepared for the quantum …

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246: Securing the Mempool: Loring Harkness on Shutter Network’s War Against MEV Attacks 30:00

4M ago30:00

30:00

Can encryption make Ethereum more fair? In this episode, I speak with Loring Harkness, the ecosystem lead at Shutter Network, about a crucial — and often ignored — issue: malicious MEV. Loring explains how MEV bots extract value from unsuspecting users through front-running and sandwich attacks — and how Shutter uses threshold encryption to stop it…

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245: Proof of Personhood in the AI Age: Humanity Protocol’s Mission with Terence Kwok 39:18

4M ago39:18

39:18

How do you prove someone is human in the AI era? In this episode, Sam Kamani speaks with Terence Kwok, the founder of Humanity Protocol — a decentralized identity blockchain now valued at over $1B. Terence shares how Humanity Protocol uses palm biometrics, ZK proofs, and partnerships with validators to establish proof of personhood, enable on-chain…

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244: From Harvard to Hardware: Hoansoo from Exabits on Web3 Compute and Scaling with GPUs 26:12

4M ago26:12

26:12

In this episode of Web3 with Sam Kamani, Sam is joined by co-host Amanda Whitcroft to interview Hoansoo Lee, co-founder of Exabits.ai. With a PhD from Harvard and deep expertise in edge computing, Hoansoo shares how Exabits is decentralizing the GPU cloud for AI by combining high-performance chips like the H100 and Blackwell with tokenized infrastr…

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243: AI Meets Storytelling – Brayden Doig on Building Abyss, the World’s First 1:1 Trading Card Game 35:05

4M ago35:05

35:05

In this episode, Brayden Doig from Abyss joins Sam Kamani to discuss his innovative trading card game powered by AI. He shares how Abyss is merging AI with storytelling to create unique, one-of-one NFTs that evolve through user choices. Brayden also dives into his involvement with the Taste Foundation and how AI can transform the entertainment land…

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242: Building the Most Fair Stablecoin: How Noon Capital Delivers Real Yield Without VC Influence 26:02

4M ago26:02

26:02

In this episode, I speak with Arpan Gautam from Noon Capital — a self-funded project building what they call the most intelligent and fair yield-bearing stablecoin. We dive into how their stablecoin (USN/sUSN) delivers through-cycle returns by allocating capital across delta-neutral strategies, and why they’re committed to distributing 90%+ of retu…

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241: AI Meets Web3 Growth—Chris Duggan on Building ChainGPT and Scaling to 1M Followers 35:38

4M ago35:38

35:38

Chris Duggan is the Senior Marketing Manager at ChainGPT and former content lead at BNB Chain (Binance). In this episode, recorded live in New York, Chris dives deep into how ChainGPT is building an expansive AI ecosystem for Web3—from smart contract generation and NFT creation to incubating new AI-native projects. We talk about ChainGPT's explosiv…

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240: Turning Real-World Assets into Liquid Crypto Products – Paul from ATV Fund 21:11

4M ago21:11

21:11

In this episode of Web3 with Sam Kamani, recorded live at Digital Asset Summit in New York, I sit down with Paul Talbert from ATV Fund to discuss how they’re transforming fixed-income investing through tokenization. Paul explains how mortgage-backed securities (MBS), a traditionally illiquid asset class, are now being made accessible, efficient, an…

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239: Improving Crypto User User Experience: Pedro from Wallet Connect 28:15

4M ago28:15

28:15

In this live-recorded episode from Digital Asset Summit in New York, Sam chats with Pedro, the founder of WalletConnect. Together, they unpack what it takes to make crypto more usable for everyday users and developers. Pedro dives into the journey of WalletConnect—from solving MetaMask's dominance to powering over 600 wallets and working with Strip…

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238: The AI-Agent Economy: Matt Wright from Gaia on Open-Source Intelligence 37:11

4M ago37:11

37:11

In this episode, recorded live from New York during the Digital Asset Summit, Sam sits down with Matt Wright — founder of Gaia and partner at EVM Capital. Matt has been building at the frontier of developer ecosystems, decentralized tech, and now AI agents. He walks us through his journey from organizing global hackathons to JP Morgan and ConsenSys…

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237: Solving Ethereum’s Liquidity Problem: Barna from Malda on Unified Lending Across Rollups 27:23

5M ago27:23

27:23

Barna, co-founder of Malda and mendi.finance, joins the podcast to break down Ethereum’s biggest DeFi problem: liquidity fragmentation. He explains how their protocol is using ZK co-processors and a host-extension chain model to unify lending and borrowing across rollups like Linea, Base, and more. We talk about why Ethereum’s growth has stalled, h…

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236: Snap, Earn, & Compete—How Snpit is Bringing GameFi to Photography 32:18

5M ago32:18

32:18

What if taking photos could earn you rewards? Most Web3 games struggle with retention, but Snpit has built a thriving community in Japan, Italy & beyond—and their users keep coming back. In this episode of Web3 with Sam Kamani, I talk to Ani from Snpit.xyz about: ✅ How Snpit gamifies photography with battles, leaderboards & NFTs ✅ The secret to acq…

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235: Trustless Trading & The Future of Finance—Alexis from Yellow.com on Disrupting Markets 31:36

5M ago31:36

31:36

What if we could trade without trusting anyone? Crypto promised decentralization, but most trading still relies on centralized exchanges. In this episode of Web3 with Sam Kamani, I sit down with Alexis from Yellow.com to discuss: ✅ Why trustless trading is the missing piece in crypto ✅ How Yellow is bringing Lightning Network principles to trading …

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234: Building Web3 Communities That Stick—Jack from TON Society on Growth, Games & Engagement 36:56

5M ago36:56

36:56

How do we bring the next billion users into Web3? So many crypto projects have promised mass adoption, but most new users don’t stick around. What if we could change that? In this episode of Web3 with Sam Kamani, I sit down with Jack from TON Society to discuss: ✅ Why Telegram’s ecosystem is key to onboarding millions ✅ How TON Society is using gam…

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233: The Next Chapter for NFTs—Neil from Mojito on Tokenized RWAs & Enterprise Web3 Strategies 28:50

5M ago28:50

28:50

Are NFTs dead? Or are they just evolving? In this episode of Web3 with Sam Kamani, I sit down with Neil from Mojito to explore how NFTs are still powering major brands, how real-world assets (RWAs) are reshaping digital ownership, and how loyalty programs in Web3 could be the next major adoption driver. Key topics we cover: ✅ How major brands like …

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231: The Rise of AI Agents — David Pinger from Warden Protocol on the Future of Autonomous Systems 30:04

5M ago30:04

30:04

🤖 Will AI agents replace human decision-making? In this episode of Web3 with Sam Kamani, I sit down with David Pinger from Warden Protocol to explore how AI agents are transforming finance, automation, and blockchain infrastructure. 🚀 Key topics we cover: 🔹 Why blockchain isn’t for humans—AI agents will drive Web3 transactions 🔹 How AI agents make …

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232: Decentralizing the Internet—Joshua Meng on How RSS3 is Building the Open Web 20:21

5M ago20:21

20:21

Is the internet becoming more centralized and restricted? 🌍 In this episode of Web3 with Sam Kamani, I sit down with Joshua Meng from RSS3 to discuss the importance of decentralizing content, making the internet more open, and how RSS3 is powering AI agents and Web3 applications. Key topics we cover: ✅ Why traditional RSS doesn’t work for Web3 ✅ Ho…

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230: Tokenizing the World—Jose from OwnChain on RWA, Staking & the Future of Finance 17:45

5M ago17:45

17:45

Can tokenization unlock financial access for millions? In this episode of Web3 with Sam Kamani, I sit down with Jose from OwnChain, live at Consensus 2025 in Hong Kong, to discuss how OwnChain is bringing real-world assets (RWA) on-chain and revolutionizing financial markets. 🔥 Key topics we cover: 🔹 How OwnChain is bridging real-world assets to De…

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239: Improving Crypto User User Experience: Pedro from WalletConnect 28:15

5M ago28:15

28:15

In this live-recorded episode from Digital Asset Summit in New York, Sam chats with Pedro, the founder of WalletConnect. Together, they unpack what it takes to make crypto more usable for everyday users and developers. Pedro dives into the journey of WalletConnect—from solving MetaMask's dominance to powering over 600 wallets and working with Strip…

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