Tackling Tetracyclines

Rumor vs Truth

In this episode, hosts Don Weinberger and Steve Small separate fact from fiction when it comes to claims about tetracyclines.

Will doxycycline stain children’s teeth?

Is expired tetracycline truly deadly?

What do cats have to do with all this?

Let’s cycle through the facts!

They’ll share research and insights into some interesting claims including:

• Doxycycline should never be used in young kids due to teeth concerns.
• Doxycycline monohydrate is better than the hyclate version.
• Minocycline can permanently pigment skin.
• Expired tetracyclines are toxic.
• Tetracyclines shouldn’t be used in pregnancy.
• Tetracyclines shouldn’t be combined with milk.

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TRC Healthcare Editor Hosts:

• Stephen Small, PharmD, BCPS, BCPPS, BCCCP, CNSC
• Don Weinberger, PharmD

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Guest:

• Michael Deaney, PharmD, AAHIVP (Clinical Pharmacist, Children’s Hospital Colorado)

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The clinical resources mentioned during the podcast are part of a subscription to Pharmacist’s Letter, Pharmacy Technician’s Letter, and Prescriber Insights:

• Article: Sort Out Tetracycline Safety in Pregnancy and Lactation
• Chart: Antibiotics in Pregnancy and Lactation

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Rumor vs Truth is a production of TRC Healthcare.

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Chapters

1. Introduction (00:00:00)

2. Welcome (00:00:21)

3. Claim: Doxycycline should never be used in kids under 8 years old due to teeth staining. (00:02:27)

4. Claim: Doxycycline monohydrate is better than doxycycline hyclate. (00:05:04)

5. Claim: Minocycline can permanently discolor skin. (00:09:31)

6. Claim: Tetracyclines are toxic when they expire. (00:11:38)

7. Claim: Tetracyclines cannot be used during pregnancy. (00:13:31)

8. Claim: Tetracyclines shouldn't be taken with food or milk. (00:15:38)

9. Summary (00:17:53)

10. Wrap-Up (00:19:04)

11. Addendum (00:21:09)