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Myelofibrosis — An Interview with Dr Raajit K Rampal on Key Presentations from the 66th American Society of Hematology (ASH) Annual Meeting (Companion Faculty Lecture)

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Manage episode 477271709 series 1464173
Content provided by Dr Neil Love. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr Neil Love or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

Featuring a slide presentation and related discussion from Dr Raajit K Rampal, including the following topics:

  • Overview of the current JAK inhibitor landscape (0:00)
  • Factors predicting clinical benefit in patients with myelofibrosis (MF) receiving ruxolitinib (3:02)
  • Clinical data supporting the use of fedratinib after prior ruxolitinib for MF (9:17)
  • Emerging clinical findings on pelabresib in combination with ruxolitinib for previously untreated MF (12:13)
  • Available clinical data with novel BET inhibitors (15:00)
  • Utility of selinexor in combination with ruxolitinib for MF previously treated with ruxolitinib (16:50)
  • Emerging efficacy and safety findings reported with imetelstat for MF (18:57)
  • Clinical findings reported with the MDM2 inhibitor navtemadlin for MF (21:15)
  • Available clinical data with the TGF-beta inhibitor elritercept for MF (24:05)
  • Other novel agents and strategies under investigation for MF (26:06)

CME information and select publications

  continue reading

1555 episodes

Artwork
iconShare
 
Manage episode 477271709 series 1464173
Content provided by Dr Neil Love. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dr Neil Love or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

Featuring a slide presentation and related discussion from Dr Raajit K Rampal, including the following topics:

  • Overview of the current JAK inhibitor landscape (0:00)
  • Factors predicting clinical benefit in patients with myelofibrosis (MF) receiving ruxolitinib (3:02)
  • Clinical data supporting the use of fedratinib after prior ruxolitinib for MF (9:17)
  • Emerging clinical findings on pelabresib in combination with ruxolitinib for previously untreated MF (12:13)
  • Available clinical data with novel BET inhibitors (15:00)
  • Utility of selinexor in combination with ruxolitinib for MF previously treated with ruxolitinib (16:50)
  • Emerging efficacy and safety findings reported with imetelstat for MF (18:57)
  • Clinical findings reported with the MDM2 inhibitor navtemadlin for MF (21:15)
  • Available clinical data with the TGF-beta inhibitor elritercept for MF (24:05)
  • Other novel agents and strategies under investigation for MF (26:06)

CME information and select publications

  continue reading

1555 episodes

All episodes

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