IMD Research Round-Up: Redox metabolism

JIMD Podcasts

Dr Luciana Hannibal, Research Group Leader / Head of Translational Metabolomics at the Centre for Integrative Biological Signalling Studies in Freiburg, and Dr Julien Park, a Physician-scientist at the Children's University Hospital Münster, are Rodrigo and Silvia's latest guests, providing a thorough overview of disorders of Redox Metabolism. Authors opinions are their own and do not represent their institutions. Papers discussed include: Targeted Metabolic Profiling of Methionine Cycle Metabolites and Redox Thiol Pools in Mammalian Plasma, Cells and Urine Behringer et al Treatment with 2-phospho-L-ascorbic acid mitigates biochemical phenotypes of heme oxygenase 1 deficiency Berendes et al Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo Murphy et al The motor system is exceptionally vulnerable to absence of the ubiquitously expressed superoxide dismutase-1 Park et al Clinical and molecular analysis of a novel variant in heme oxygenase-1 deficiency: Unraveling its role in inflammation, heme metabolism, and pulmonary phenotype Berendes et al Redox signaling in inherited diseases of metabolism, Current Opinion in Physiology Jacobsen and Hannbal Real-time detection of enzymatically formed hydrogen sulfide by pathogenic variants of cystathionine beta-synthase using hemoglobin I of Lucina pectinata as a biosensor. Myszkowska et al