Preserve Muscle, Burn Fat: How to Outsmart Your Metabolism with Dr. Eric Ravussin

Optimal Protein Podcast with Vanessa Spina

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Today’s episode features world-renowned metabolism expert Dr. Eric Ravussin, whose groundbreaking work has transformed our understanding of energy balance, calorie restriction, and long-term fat loss. Dr. Ravussin shares key insights from decades of clinical research on how the body adapts to weight loss—including why your metabolism slows, how to preserve lean muscle, and the critical role of mitochondrial health and metabolic flexibility.

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We discuss:

• What “metabolic adaptation” really is and how it affects fat loss

• Why your body defends against weight loss more than weight gain

• The role of protein intake in preserving lean mass

• How to counteract muscle loss during caloric restriction

• Metabolic flexibility and its connection to insulin resistance

• GLP-1 medications like semaglutide and their impact on muscle loss

• The connection between mitochondrial function, aging, and energy expenditure

• Why resistance training is essential—especially for women and older adults

This conversation is packed with evidence-based strategies for anyone pursuing sustainable fat loss, muscle preservation, and long-term metabolic health.

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The content provided in this podcast is for informational purposes only and should not be construed as medical advice. Consult with a healthcare professional before making significant changes to your diet or exercise regimen.