Best Josh Blum Podcasts (2025)

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Ep179: Ethan Weiss & Josh Lehrer on a New Idea for Cardiovascular Disease & Diabetes 1:03:25

1h ago1:03:25

1:03:25

Marea Therapeutics CEO Josh Lehrer and CSO Ethan Weiss on a new angle of attack against cardiovascular disease and diabetes.By Timmerman Report

1
Trust for Public Land Economic Impact of Mountain Biking with Jennifer Clinton and J.T. Horn | 192 59:10

8d ago59:10

59:10

For Episode 192 we have Jennifer Clinton and J.T. Horn both of the Trust for Public Land. Earlier this year the Trust for Public Land Partnered with IMBA to author a report on the Economic Impact of Mountain Biking. They also presented this report at the International Trail Summit that was held this past April in Madison, WI. We dug into the report…

1
Ep178: Peyton Greenside on ML-Guided Biologics Discovery 1:02:56

15d ago1:02:56

1:02:56

Peyton Greenside, co-founder and CEO of BigHat Biosciences, on machine-learning guided biologic drug discovery.By Timmerman Report

1
Lars Romig | Trail Builder & Advocate for Mountain Biking | Sedona, AZ | 191 1:17:39

1M ago1:17:39

1:17:39

For Episode 191 we have Lars Romig of Sedona, AZ. Lars has been a long-time member of the Verde Valley Cyclists Coalition, along with being a Trail Builder and Mountain Bike Trail Access Advocate. Most Recently Lars led the charge on building the Hardline Trail. This conversation is one that I’ve wanted to have with a Sedona Local for a handful of …

1
Ep177: Kevin Parker on Finding Cancer Drug Targets 58:13

1M ago58:13

58:13

Kevin Parker, CEO of Cartography Biosciences, on finding new cancer drug targets.By Timmerman Report

1
Chris Riley of Central Maine Chapter New England Mountain Bike Association | 190 1:18:00

2M ago1:18:00

1:18:00

For Episode 190 we have Chris Riley from Central Maine. Chris is the president of the Central Maine Chapter of the New England Mountain Bike Association, and a board member of the New England Mountain Bike Association. Chris and his organization have come up with some innovative ideas on how to handle both new trail construction as well as handling…

1
Ep176: David Roblin on Building a TechBio Company 1:19:28

2M ago1:19:28

1:19:28

David Roblin, CEO of London-based Relation Therapeutics, on building a techbio discovery company.By Timmerman Report

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Birmingham Urban Mountain Pedalers AKA BUMP with Chase Draper | 189 1:16:52

2M ago1:16:52

1:16:52

For Episode 189 we have Chase Draper the President of Birmingham Urban Mountain Pedalers otherwise known as BUMP. BUMP is another powerhouse volunteer driven trail organization that falls under the SORBA mothership in the South East region of the United States. Chase provides some exceltent stories about what can be accomplished when you are willin…

1
Ep175: Andy Scharenberg on in vivo CAR-T cell therapies 1:10:46

2M ago1:10:46

1:10:46

Andy Scharenberg, CEO of Seattle-based Umoja Biopharma, on developing in vivo CAR-T cell therapies.By Timmerman Report

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Ep174: Najat Khan on the TechBio Movement 1:07:16

3M ago1:07:16

1:07:16

Najat Khan, chief R&D and chief commercial officer of Recursion, on using technology to improve drug discovery.By Timmerman Report

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Jarrod’s Place Bike Park | Trail Armor | With Jarrod & Josh | 188 1:22:33

4M ago1:22:33

1:22:33

For Episode 188 we have Jarrod Harris and Josh Cohan back on from Jarrod’s Place Bike Park. We cover a handful of topics including what Josh & Jarrod have learned since opening Jarrod’s Place Bike Park and we went deep on All things Trail Armor – The first line of defense for protecting your Flow Trails, Jump Lines and Berms. There’s a lot of great…

1
Ep173: Robert Blum on Building a Fully Integrated Biopharma For Muscle Disorders 57:56

4M ago57:56

57:56

Robert Blum, CEO of South San Francisco-based Cytokinetics, on building a fully integrated biopharma to treat muscle disorders.By Timmerman Report

1
IMBA Education and Programing in 2025 with John Cox – Education Manager and Marty Caivino – Local Community Engagement Manager | 187 52:14

4M ago52:14

52:14

For Episode 187 we have Marty Caivano the Local Community Engagement Manager for IMBA and John Cox the Education Manager for IMBA. We discussed many topics including The IMBA Foundations (Formerly known as IMBA Trail Labs), along with a lot of the other community engagement and educational programs that IMBA is continuing to host in 2025… There is …

1
Ep172: Mostafa Ronaghi on Studying Live Cells at Scale 1:20:53

4M ago1:20:53

1:20:53

Mostafa Ronaghi, co-founder and executive board member of Cellanome, on developing technology to look at live cells and cellular interactions at scale.By Timmerman Report

1
Jason Aric Jones | 30+ Years of Mountain Bike Trail Access and Advocacy in Michigan | 186 1:30:50

4M ago1:30:50

1:30:50

For Episode 186 we have Jason Aric Jones. Jason recently announced that he was stepping away from 30+ years of working extremely hard for mountain bike trail access and advocacy, and I know that it would be important to have Jason on the show to recount some of the experiences he has had along the way. Jason definitely took a creative approach to g…

1
Ep171: Ram Aiyar on RNA Editing Medicines 1:01:48

5M ago1:01:48

1:01:48

Ram Aiyar, CEO of Cambridge, Mass.-based Korro Bio, on RNA editing medicines.By Timmerman Report

1
Ep170: David Schenkein on Investing in the Future of Biotech 59:52

5M ago59:52

59:52

David Schenkein, general partner at GV, on investing in the future of biotech.By Timmerman Report

1
Story Time with Steve Kasacek | Outdoor Sport Institute of Maine | Trail Planning and Design | 185 1:48:26

5M ago1:48:26

1:48:26

For Episode 185 we have Steve Kasacek back for his second appearance on Trail EAffect. Steve is the assistant Director of the Outdoor Sport Institute located in Maine. We covered a ton of various trail projects that Steve has been a part of in Maine, along with the value of building relationships. Topics Include: Updates with the Outdoor Sport Inst…

1
Uriah Steber with Benchmark Trails | Oahe Wheelmen | 2025 South Dakota Bicycle Summit | 184 58:40

5M ago58:40

58:40

For Episode 184 we have Uriah Steber, the Owner of Benchmark Trails, Founding Member of the Oahe Wheelmen, and a driving force behind the rise of trails and mountain Biking across the State of South Datoka. Topics Include: The creation of the Oahe Wheelmen and MT Biking in Pierre, SD The rise of trails and mountain biking in rural communities The s…

1
Ep169: Kevin Fitzgerald on the Past & Future of RNAi Medicines 1:02:28

6M ago1:02:28

1:02:28

Alnylam Pharmaceuticals chief scientific officer Kevin Fitzgerald on the past, present & future of RNA interference medicines.By Timmerman Report

1
2024 SORBA Year in review and 2025 Updates with Philip Darden | 183 59:00

6M ago59:00

59:00

2024 SORBA Year in review and 2025 Updates with Philip Darden | 183 For Episode 183 we have Philip Darden back on. Philip is the executive director of the Southern Off-Road Bicycle Association otherwise known as SORBA. During this conversation we recap some of the more notable events that Philip was able to attend in 2024, how the region was impact…

1
Ep168: Jonathan Bricker on How to Quit Smoking & Prevent Cancer 1:00:23

6M ago1:00:23

1:00:23

Jonathan Bricker, professor in the cancer prevention program at Fred Hutchinson Cancer Center, on how to quit smoking with help from tech and biotech tools.By Timmerman Report

1
Pisgah Area SORBA Hurricane Helene Update with Daniel Sapp | 182 53:15

6M ago53:15

53:15

For Episode 182 we have Daniel Sapp back on, this time Daniel is here to provide some insight around the impacts that Hurricane Helene had on Western North Carolina and the Communities around the Pisgah National Forest. Western North Carolina relies heavily on tourism, please consider supporting these communities and organizations in any way that y…

1
Ep167: Leslie Williams on transfer RNA therapies 1:11:28

7M ago1:11:28

1:11:28

Leslie Williams, CEO of Boston-based hC Bioscience, on developing transfer RNA therapies.By Timmerman Report

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Brice Shirbach | Mountain Bike Community Storyteller | Underexposed Series | 181 1:21:10

7M ago1:21:10

1:21:10

For episode 181 We have Brice Shirbach for his third appearance on Trail EAffect. Brice knows trail communities like no other. Brice has been at this for well over a decade now and it shows! We covered how his Underexposed series came to be and, some of the communities that Brice has covered recently through the Underexposed Series. Brice has a ver…

1
Ep166: Chris Garcia on Engineering Protein Drugs for Cancer, Autoimmunity 1:03:35

8M ago1:03:35

1:03:35

Chris Garcia, professor at Stanford University and co-founder of several biotech startups, on using protein engineering to advance new treatments for cancer and autoimmune diseases.By Timmerman Report

1
Charles Evans – Trail Maintenance Coordinator for the Snowshoe Highlands Area Recreation Collaborative | IMBA Silver Level Ride Center | Pocahontas County, WV | 180 59:47

8M ago59:47

59:47

For episode 180 we have Charles Evans. Charles is the Trail Maintenance Coordinator for the Snowshoe Highlands Area Recreational Collaborative. The Snowshoe Highlands Region has nearly 400 miles of trail, is a IMBA Silver Level Ride Center, and is the region that has hosted Several World Cup Mountain Bike Races and Championships. We covered the eve…

1
Ep165: Zach Hornby on Tackling Cancer Drug Resistance 1:02:45

8M ago1:02:45

1:02:45

Zach Hornby, CEO of San Diego-based Boundless Bio, on tackling cancer drug resistance.By Timmerman Report

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Luke Krolikowski – Bike Park Manager of the Farside Bike Park at Chestnut Mountain Resort | 179 53:30

9M ago53:30

53:30

For episode 179 we have Luke Krolikowski – the Bike Park Manager of the Farside Bike Park at Chestnut Mountain Resort in Galina, IL. The Farside Bike Park is a relatively newer lift access bike park located in a topographically rich part of the upper Midwest known as the Driftless Area. Luke dives into all things Farside during our conversation. If…

1
Ep164: Ted Love and Alan Anderson on Raising the Bar for Sickle Cell Disease Patients 56:39

9M ago56:39

56:39

Ted Love, chairman of BIO, and Dr. Alan Anderson, executive director of Sickle Forward, on how to improve quality of life for sickle cell disease patients around the world.By Timmerman Report

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International Trail Rating System (ITRS) for Mountain Biking with Mischa Crumbach and Edoardo Melchiori | 178 2:12:40

9M ago2:12:40

2:12:40

For Episode 178 We’ve got Mischa and Edoardo the two masterminds behind the International Trail Rating System. Mischa is based in Switzerland, and Edoardo is based in Italy. Both have a strong understanding about the nuance that goes into dissecting and rating a trail. While there is a lot that can go into how or why a trail is rated a certain way,…

1
Ep163: Sarah Boyce on RNA Medicines for Muscle Diseases 1:08:19

10M ago1:08:19

1:08:19

Sarah Boyce, CEO of San Diego-based Avidity Biosciences, on RNA medicines for rare muscle diseases.By Timmerman Report

1
Emily Brown | Spearfish Trails Coalition | Spearfish, SD Mountain Biking | SRAM | 177 1:14:20

10M ago1:14:20

1:14:20

For Episode 177 we have Emily Brown. Emily is a Co-Founder of the newly created Spearfish Trails Coalition based in Spearfish, SD. If you haven’t been to the Black Hills in South Dakota, this place is truly remarkable. Spearfish has a history of trails and mountain biking that runs parallel with the history of mountain biking itself. Emily discusse…

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Mike Gehard – The President of SORBA Chattanooga, TN All things Trails and Mountain Biking in Chattanooga – 176 1:17:30

10M ago1:17:30

1:17:30

For Episode 176 we have Mike Gehard, Mike is the current president of SORBA Chattanooga. If you’ve been following along for a while, you’ve heard several guests talk about Walden’s Ridge in Chattanooga, now you’ll get the full story on mountain biking in Chattanooga along with the fact that SORBA Chattanooga is currently looking to hire their first…

1
Ep162: Sean McClain on AI for Biologic Drug Discovery 1:05:59

11M ago1:05:59

1:05:59

Sean McClain, CEO of Absci, on using AI to speed up biologic drug discovery.By Timmerman Report

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Glen Jacobs of WorldTrail – Trail Design | Knowledge Sharing | Trail Building Innovation from Around the World | Mountain Biking is just beginning – 175 2:36:45

11M ago2:36:45

2:36:45

For Episode 175 we have Glen Jacobs back for Round 2 on Trail EAffect. Glen first appeared on episode 125, if you haven’t listened to the first conversation with Glen, I highly recommend it as, episode 125 will provide some context for this conversation. Glen is easily one of the most prolific visionaries in Trail Building. Glen Co-founded WorldTra…

1
Ep161: Jeff Stein on a Long-Lasting Flu Drug 1:08:51

11M ago1:08:51

1:08:51

Jeff Stein, CEO of San Diego-based Cidara Therapeutics, on a long-lasting drug against flu.By Timmerman Report

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Daniel Sapp – President of Pisgah Area SORBA / Trail Advocacy 174 1:27:54

11M ago1:27:54

1:27:54

Daniel Sapp – President of Pisgah Area SORBA / Trail Advocacy 174 For Episode 174 we have Daniel Sapp, Daniel is the current president of Pisgah Area SORBA, co-founder of The Backslope as well as colleague to the infamous Seth Alvo of Berm Peak. Prior to this Daniel was a journalist for Pinkbike, among other publications and Daniel has spent most h…

1
Ep160: Abe Ceesay on Precision Neuroscience 1:08:48

12M ago1:08:48

1:08:48

Abe Ceesay, CEO of Boston-based Rapport Therapeutics, on a precision medicine approach to neuroscience drug discovery.By Timmerman Report

1
Steve Ford - Bike Park Manager of the Luiseño Bike Park in San Diego, California – 173 56:15

12M ago56:15

56:15

Steve Ford - Bike Park Manager of the Luiseño Bike Park in San Diego, California – 173 For Episode 173 we have Steve Ford – Steve is the Gravity Bike Park Manager at the Luiseño Bike Park located in San Diego County California on the La Jolla Band of Luiseño Indian Tribal Lands. We covered all things Gravity Bike Parks from Steve’s experience and h…

1
Ep159: Jimi Olaghere on Being Functionally Cured of Sickle Cell Disease 1:07:22

12M ago1:07:22

1:07:22

Jimi Olaghere is one of the first patients to have been functionally cured of sickle cell disease with a CRISPR gene-edited cell therapy.By Timmerman Report

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Jeremy Poore from Old Fort, NC / McDowell Tech Trail School / Mountain Top Shuttles - 172 1:28:05

1y ago1:28:05

1:28:05

Jeremy Poore from Old Fort, NC / McDowell Tech Trail School / Mountain Top Shuttles #172 For Episode 172 we have Jeremy Poore – who is based in Old Fort, NC which is not too far east of the Infamous Ashville, NC. Old Fort is ramping up to be the next community to embrace the benefits of trails and outdoor recreation. We covered all things Old Fort,…

1
Ep158: David Younger and Randolph Lopez on SynBio & AI for Discovery 1:00:44

1y ago1:00:44

1:00:44

David Younger and Randolph Lopez, co-founders of A-Alpha Bio, on using synthetic biology and AI to discover new biologic drugs.By Timmerman Report

1
Amanda Carey – President of NICA – National Interscholastic Cycling Association – Talking Trails, Youth Development, Leadership and Non-Profits – 171 1:25:15

1y ago1:25:15

1:25:15

Amanda Carey – President of NICA – National Interscholastic Cycling Association – Talking Trails, Youth Development, Leadership and Non-Profits – 171 For Episode 171 we have Amanda Carey as our guest. Amanda is the president of NICA, the National Interscholastic Cycling Association. Amanda worked for 5 other Outdoor and Trail Based non-profits lead…

1
Ep157: Vineeta Agarwala of A16Z on Investing in AI for Drug Discovery 56:33

1y ago56:33

56:33

Vineeta Agarwala, general partner at A16Z's Bio & Health fund, on investing in AI for drug discovery.By Timmerman Report

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Peter Mills of Elevated Trail Design - 170 1:00:36

1y ago1:00:36

1:00:36

Peter Mills of Elevated Trail Design - 170 For Episode 170 we have Peter Mills the owner of Elevated Trail Design as our guest. Elevated Trail Designs is a PTBA Member Company that is based out of the Ashville, NC Region. Peter is a lifelong mountain biker and trail builder that is responsible for some of the newest yet most notable trail projects …

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Ep156: David Liu on New Tools and Techniques for Biology 1:52:57

1y ago1:52:57

1:52:57

David Liu, professor of chemistry at Harvard University and co-founder of multiple biotech companies, including Beam Therapeutics and Prime Medicine.By Timmerman Report

1
Toby Cortez / Bogue Chitto State Park / Mountain Biking in Louisiana 169 1:08:21

1y ago1:08:21

1:08:21

Toby Cortez / Bogue Chitto State Park / Mountain Biking in Louisiana 169 For Episode 169 Toby Cortez is our guest – Toby is one of the masterminds behind the mountain bike trails at Bogue Chitto State Park located in Louisiana. Toby drops a ton of knowledge on this episode, through some incredible stories about how Bogue Chitto came to be, cutting …

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Loam Pass with Rob Brown and Joey Foresta - 168 1:08:45

1y ago1:08:45

1:08:45

Loam Pass with Rob Brown and Joey Foresta - 168 For episode 168 we’ve got Rob Brown and Joey Foresta – Co Founders of the Loam Pass. The Loam Pass is your North American Gravity Bike Park Pass, and its brand new for 2024. Rob and Joey Teamed up to create the Loam Pass, and it launched in March with 30 resorts and shuttle services, with additional l…

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Women in Trail Building at the 2024 Professional Trail Builders Association Sustainable Trail Conference 167 1:04:40

1y ago1:04:40

1:04:40

Women in Trail Building at the 2024 Professional Trail Builders Association Sustainable Trail Conference 167 At the end of day one during the 2024 Professional Trail Builders Association Sustainable Trails Conference Martha Becton took over as host of the Trail EAffect Podcast. Martha brought Erin Amadon, Rebekah Morrisson, and Addie Clayton onto t…

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