Best Empowering Pumps Podcasts (2025)

1
Total Cost of Ownership and the Future of Pump Innovation 17:24

6d ago17:24

17:24

This week Charli is joined by Tomas Dobrovolskis Connect with him on LinkedIn Join us at EPIC, November 5th and 6th at San Jacinto College in Pasadena, TX Find us @EmpoweringPumps on Facebook, LinkedIn, Instagram and Twitter and using the hashtag #EmpoweringIndustryPodcast or via email [email protected]…

1
💉 Pump, 📉 Pressure, ⚡ Power: Inside the STEMI Shock Solution 4:26

17h ago4:26

4:26

New Insights from the DanGer Shock Trial! 🫀💡 Can early left ventricular unloading with a microaxial flow pump (mAFP) save lives in STEMI-related cardiogenic shock? This compelling substudy shows that mAFP not only boosts cardiac output and power, but also reduces pulmonary pressures—all while using less pharmacologic support. 📉💊 🧪 Native CO improve…

1
🌐 ACHIEVE-1 Decoded: Efficacy & Safety of Orforglipron in Type 2 Diabetes 3:43

23h ago3:43

3:43

🚨 New Breakthrough in Type 2 Diabetes Care! 💊🧬 The ACHIEVE-1 trial shows that Orforglipron, a once-daily oral, nonpeptide GLP-1 receptor agonist, delivers significant reductions in HbA1c and body weight—without injections and with minimal restrictions! 🌍📉 👨‍⚕️ 559 patients across 5 countries ⏱️ 40 weeks, 3 dosing arms (3, 12, 36 mg) 📊 HbA1c ↓ by up…

1
Frailty as a Cardiovascular Compass 🧭📉🩻 4:54

1d ago4:54

4:54

🚨 Frailty matters — even in the cath lab! 🧓🫀 A new NCDR registry analysis of 1.3M+ older adults shows a clear gradient: as frailty increases, so do complications, mortality, and procedural risks during PCI. Severely frail patients faced a striking 20.3% in-hospital mortality and >50% mortality with cardiogenic shock. 🧠 It’s time to treat frailty as…

1
🧬 Amylin & GLP-1: Double Agents for Weight Loss & DM-CagriSema (Part II) 7:00

2d ago7:00

7:00

🚨 Major breakthrough in obesity pharmacotherapy! The REDEFINE-1 & REDEFINE-2 trials show that once-weekly CagriSema (Cagrilintide + Semaglutide) delivers up to 20% weight loss in people with obesity—and significant glycemic improvements in those with type 2 diabetes. 💉📉 🌍 Global, double-blind RCTs ⚖️ >90% lost ≥5% body weight 🩺 SBP ↓, QoL ↑, predia…

1
🌲 Burning Risk: How Wildfires Ignite Heart Failure 📉 4:23

3d ago4:23

4:23

🔥 New Study Alert! 🩺 Wildfire smoke isn’t just a respiratory threat — it’s taking a toll on the heart, especially in older adults. 📊 A nationwide Medicare cohort (~22M) shows that long-term exposure to wildfire-specific PM2.5 is linked to significantly higher heart failure risk — more so than urban pollution. 📍 Vulnerable groups — women, Medicaid-e…

1
🧬 Amylin & GLP-1: Double Agents for Weight Loss (Part 1) 6:10

3d ago6:10

6:10

🧠💊 Appetite Meets Its Match: The Amylin Advantage” In this episode of Got Knowledge Doc, we explore how amylin, the lesser-known hormone co-secreted with insulin, is making a comeback — this time as part of a dual receptor strategy with GLP-1. 💡 Learn how amylin: 🧠 Activates brainstem satiety centers ⏳ Delays gastric emptying 📉 Suppresses glucagon …

1
⏱️🩸 Timing is Brain: Early DOACs in Atrial Fibrillation 4:43

4d ago4:43

4:43

🧠💉 When should you start anticoagulation after an ischaemic stroke in atrial fibrillation? The CATALYST meta-analysis may have the answer! 📊 5,441 patients from 4 RCTs ⏱️ Early DOAC (≤4 days) reduced recurrent stroke risk at 30 days ⚖️ No increased bleeding, even in moderate stroke severity 🚫 But patients with PH2 or very severe strokes were exclud…

1
🧠 Restore, Regulate, Reimagine Type 1 Diabetes 3:18

4d ago3:18

3:18

🚨 Breakthrough in Type 1 Diabetes! 🧬💉 A new study in NEJM shows that zimislecel, a fully differentiated stem cell–derived islet therapy, restored insulin production and led to insulin independence in 83% of participants! ✅ 📉 HbA1c dropped, 📈 time-in-range soared to 93%, and ⚖️ glucose variability was dramatically reduced. This marks a major step to…

1
🧘‍♂️📉 Fitness on the Floor: Predicting Death with a Sit 3:48

5d ago3:48

3:48

🧘‍♂️ How Well Can You Sit and Rise from the Floor? 🪑⬆️ That simple motion might say more about your longevity than you think. A 12-year study of 4,282 adults found that lower Sit–Rise Test (SRT) scores predicted 3.8x higher natural death and 6x higher cardiovascular death rates. 😱 ✅ No equipment ✅ Under 2 minutes ✅ Predicts survival Why aren’t we u…

1
Dr. RR Baliga’s Philosophical Discourses: Aristotle (Greece, 384–322 BCE) – Founder of the Lyceum 2:38

5d ago2:38

2:38

Aristotle (384–322 BC), a Greek philosopher and polymath, founded the Peripatetic school and Lyceum in Athens. His extensive works spanned diverse fields, including logic, ethics, politics, biology, and metaphysics, profoundly influencing Western thought, science, and philosophy.By MasterMedFacts LLC

1
⚡Gatekeepers of Strength: Allopurinol, Calcium & the RyR Revolution 4:23

5d ago4:23

4:23

⚡Gatekeepers of Strength: Allopurinol, Calcium & the RyR Revolution”! Did you know that an old gout drug might hold the key to reversing age-related muscle weakness and heart failure? Using cryo-EM, researchers found that allopurinol and xanthine derivatives directly activate ryanodine receptors—calcium channels essential for muscle contraction. 💡 …

1
🧠🔥 Flame Within the Brain: Neuroinflammation Decoded 5:24

6d ago5:24

5:24

🧠🔥 Neuroinflammation: The Common Flame in MS, Stroke, Alzheimer’s & Parkinson’s Why do microglia flip from guardians to arsonists? How does immune cell infiltration differ between MS and AD? And which CNS-penetrant therapies show the most promise in dousing the inflammatory fire? In our latest Got Knowledge Doc podcast, we decode the science behind…

1
EF Up, Risk Still On 📈🧠⚠️: Understanding the Fragile Success of HF Recovery 6:00

7d ago6:00

6:00

🔬💓 New Insights on HFimpEF 💓🔬 Heart Failure with Improved Ejection Fraction (HFimpEF) is no longer just a transition phase—it’s a distinct, dynamic phenotype with its own risks and management needs. From biomarkers and imaging to the latest trials like PROSPER-HF and FINEARTS-HF, we’re entering an era of more personalized care for these patients. 📈…

1
🧠 🎛️💡 Master Control: Is the Brain Orchestrating Aging? 2:28

7d ago2:28

2:28

🧠 Is your brain orchestrating how fast you age? New insights suggest that aging isn’t just about wear and tear—it may be centrally coordinated by the brain through molecules like GDF15, responding to stress, senescence, and energy demands. 💬 Fascinating findings from Nature (June 2025) show how psychological stress accelerates aging at a cellular l…

1
💊❤️🔥Obesity:- Hormones, Hearts, and Hope; The Cardiologist’s New Toolkit 6:07

8d ago6:07

6:07

“Obesity Rx 💊❤️🔥: Hormones, Hearts, and Hope” The 2025 ACC guidance reframes obesity as a chronic disease—with precision therapies like GLP-1/GIP agonists now essential in cardiology. We explore NuSH therapies (semaglutide, tirzepatide), the latest trial data, clinical thresholds for risk reduction, and practical steps for de-stigmatizing care. 👉 T…

1
🥗🧬💊 “Eat Less or Pop a Pill? Rapamycin vs. Metformin 3:48

8d ago3:48

3:48

🔬 New meta-analysis alert! 🧪 Researchers compared rapamycin and metformin to dietary restriction across 167 studies in 8 vertebrate species. 📈 Key finding: Rapamycin mirrors dietary restriction’s longevity benefits—but metformin falls short. ⚠️ High heterogeneity and species bias remind us: translation to human health still needs careful navigation…

1
🫀 Cells, Senescence, and Survival: How the Heart Ages 5:42

9d ago5:42

5:42

🫀 The Heart Ages—But Can We Intervene? New insights from Nature Reviews Cardiology highlight how endothelial dysfunction, inflammageing, CHIP, and senescence-associated secretory phenotypes (SASP) drive cardiovascular ageing. Promising interventions—from gerotherapeutic diets and exercise to NAD+ boosters, senolytics, and ACBP neutralization—may he…

1
🧬Genes, Clocks, and Global Gaps: UN Insights on Aging 4:05

9d ago4:05

4:05

We unpack the UN Scientific Advisory Board Brief on Aging—from telomeres and epigenetic clocks 🧫 to senolytics 💊 and AI-driven geroscience 🤖. Why does aging matter to every clinician? Because aging is the common soil of all chronic disease. 🌱 🔗 Listen now and join the longevity conversation! #Aging #UNBrief #Geroscience #Epigenetics #Healthspan #Go…

1
🧠 Brains, Beating Hearts, and Bioethics: Human Cells in Animal Bodies 💓 4:02

10d ago4:02

4:02

🚨 Game-changing breakthroughs in chimaera research! 🧬💓 From beating human hearts grown in pig embryos to human organoids integrating into mouse intestines and brains via amniotic injection—two bold advances are reshaping the future of organ transplantation and regenerative medicine. But with scientific promise comes ethical complexity. How far shou…

1
Vitamin D: Broad Hopes, Narrow Proof? 3:11

10d ago3:11

3:11

🌞 New Guidelines on Vitamin D Supplementation! 💊🧪 JAMA’s latest synopsis recommends empirical vitamin D dosing—without routine testing—for children, the elderly, pregnant women, and those with prediabetes. The evidence? Conditional, with wide confidence intervals—but the low cost and minimal harm may tip the scales. Let’s discuss: Is this the dawn …

1
.📜 “The Brussels Declaration 🎯: Prevent the Preventable: The Lp(a) Revolution Begins 2:39

11d ago2:39

2:39

🚨 One in five people carry a hidden cardiovascular risk—do you? The Brussels Declaration on Lipoprotein(a) calls for global, once-in-a-lifetime Lp(a) testing to prevent premature heart disease and stroke. With strong scientific backing and health equity at its core, this is a pivotal step toward personalized cardiovascular prevention. 🧬 Let’s test …

1
Switching Gears: From Fetal Hemoglobin to Gene Therapy 3:53

11d ago3:53

3:53

From baby blood to breakthrough cures — we explore how unlocking fetal hemoglobin through gene editing (exa-cel/Casgevy) is transforming treatment for sickle cell disease and β-thalassemia. 🧬✂️ Featuring the science of BCL11A, CRISPR therapies, and what the future holds for global access 🌍💉 🎧 Tune in: “Switching Gears: From Fetal Hemoglobin to Gene…

1
Valve by Valve: Treat Early, Treat Right, Treat Once 3:47

12d ago3:47

3:47

Treat it Early. Treat it Right. Treat it Once. New Lancet comment calls for a paradigm shift in heart valve disease care—advocating early referral, multidisciplinary heart networks, and lifetime management strategies that prioritize durability over delay. Surgery isn’t the villain—delay is. #Cardiology #HeartValveDisease #PrecisionMedicine #Surgica…

1
Dr RR Baliga's Philosophical Discourses: Vasubandhu (India, c. 4th Century CE) – Co-Founder of Yogacara School 3:38

12d ago3:38

3:38

Vasubandhu was a 4th–5th century Indian Buddhist monk, philosopher, and co-founder of the Yogācāra school of Mahayana Buddhism. Renowned for his works on Abhidharma, he developed key philosophical concepts such as “consciousness-only” (vijñaptimātra) and authored texts on Buddhist metaphysics, logic, and meditation. His influential treatises, inclu…

1
Shear Genius: Clot Control, Microstructure Mastery, Revascularization 🚀🧠🔬 3:19

13d ago3:19

3:19

🧠💥 New spin on stroke care! The Milli-Spinner thrombectomy device shrinks clots by up to 95% using shear + compression — no rupture, no fragments. 🚑 Achieves revascularization in 90%+ cases, even when aspiration fails. #Stroke #Innovation #NeuroTech 🔄🩸🔬 📖 https://doi.org/10.1038/s41586-025-09049-0By MasterMedFacts LLC

1
🔥 Age, Immune, Inflamming: Cracking the Code of Aging 🧬🛡️ 6:38

13d ago6:38

6:38

🔥 Immunosenescence + Inflammaging = Aging’s hidden engines. 🧬 New studies link immune decline to frailty, dementia, and disease. 🥗💉 Sleep, diet, vaccines, and GLP-1s may slow the clock. #Healthspan > #Lifespan 💡👴🛡️ Derived from Dr. Eric Topol’s Ground Truths on Substack.By MasterMedFacts LLC

1
What’s in the Water? Compliance, Chemistry, and Courage 17:23

13d ago17:23

17:23

Charli has Lindie Aragon on this week to talk about her work with water Lindie Aragon holds a Bachelor of Science in Ecology and Evolutionary Biology from the University of Colorado and a Master of Science in Environmental Science from the University of Idaho. With a strong academic foundation in biological and environmental systems, Lindie has bui…

1
Beyond the Blockage: Arrhythmias, Aging, and Aortic Storms ⏳⚡🌀 2:45

14d ago2:45

2:45

Heart attacks & strokes are down, but guess what’s rising? ⚡ Atrial fibrillation, 🫀 valve disease, & 🩸 VTE are taking the lead! It’s time to rethink prevention: from plaque to pulse to prognosis. 🧠💊📊 #CardioTwitter #HeartHealth #TheLancet https://doi.org/10.1016/S0140-6736(25)00990-0By MasterMedFacts LLC

1
Fructose, Anxiety, Fear, and the Brain 🍭😨🧠 3:35

14d ago3:35

3:35

🧠🍬 New study in Nature reveals: High-fructose exposure in early life impairs brain development by suppressing microglial phagocytosis via GLUT5 ➡️ HK2-driven metabolic rewiring. Result? 🐭 develop anxiety-like behavior. Cut the sweet talk. Think before you drink. #NeuroScience #FructoseFacts #MentalHealth 🧪🍼…

1
🏃‍♂️ Weight, Wellness, and the Weakening Heart 4:28

15d ago4:28

4:28

🚨 New 2025 ACC Statement! Obesity worsens heart failure—but weight loss changes the game. 🏃‍♂️ Lifestyle helps. 💊 Semaglutide & tirzepatide show promise in HFpEF. 🔬 Rethink BMI. ⚖️ Precision + empathy = better outcomes. 👇 Dive into key takeaways. #CardioTwitter #Obesity #HeartFailureBy MasterMedFacts LLC

1
Forks, Frailty, and Forgetfulness 🦷➡️🧠: Mapping Malnutrition in Old Age 4:01

15d ago4:01

4:01

👵🍽️ Malnutrition in aging isn’t just about food — it’s frailty, forgetfulness, and function. The DoMAP model 🧠🔺 reveals how low intake, high needs, and poor absorption collide with social, physical & mental challenges. Let’s fix the hidden hunger. 🥣❤️ #Geriatrics #Malnutrition #HealthyAgingBy MasterMedFacts LLC

1
💊 Ditch the Aspirin? 🔄 P2Y12 Prevails 🛡️ After PCI 4:30

16d ago4:30

4:30

🚨 New BMJ meta-analysis! After PCI & stopping DAPT, P2Y12 inhibitor monotherapy 💊 reduces MACCE 🧠❤️ (HR 0.77) vs aspirin — without more major bleeding 💉 🫀 MI & stroke ↓ 📊 16,117 pts, 5 trials 🧠 Smarter post-PCI strategy? #CardioTwitter #BMJ #PCI #P2Y12 #Aspirin 🚫By MasterMedFacts LLC

1
💉 T Cells, TCF7, and Time ⏱️: The Immune Key to Longevity: When transcription meets transformation 4:09

16d ago4:09

4:09

🧬 New study in Aging Cell finds immune resilience—anchored by TCF7 expression—confers a 🚀 15.5-year survival advantage! 💥 SAS-1 high / MAS-1 low = 🔑 to longevity 👵 Midlife is the window. 🧠 Age is biology, but resilience is destiny. #Longevity #Aging #Immunology #TCF7By MasterMedFacts LLC

1
🫀 Hearts, Hope, and Health for All: Lancet Editorial 3:19

17d ago3:19

3:19

🫀 Cardiovascular breakthroughs abound—yet millions still die needlessly. 🌍 Innovation without equity is like a heart without a pulse. 💡 From molecules to communities, it’s time to turn science into survival. #GlobalHealth #CardioCare #EquityMattersBy MasterMedFacts LLC

1
Migraines: “Prodrome, Precision, Prevention 💫🧠💊” 3:33

17d ago3:33

3:33

🚨New insights from the PRODROME trial! 💊 Ubrogepant 100mg, given before the migraine hits, reduced photophobia, fatigue & brain fog—within hours! 🧠 Targets the prodrome, not just the pain. 📈 A paradigm shift in migraine care? #Migraine #CGRP #NeuroTwitter N 🔗 https://doi.org/10.1038/s41591-025-03679-7…

1
Finerenone + Empagliflozin: Combo Wins 🥇 3:22

18d ago3:22

3:22

💊 Big win for kidneys! In the CONFIDENCE trial, combo therapy with #Finerenone + #Empagliflozin 📉 slashed albuminuria 29–32% more than either alone in CKD + T2D patients 🧪🛡️ Safe, fast, and promising! 👥⏱️✅ #Nephrology #CardioRenal #SGLT2i #NEJM 🧬🩺By MasterMedFacts LLC

1
Blindness, Breakthroughs, Biotech 🧬 From Darkness to Light via Nanoscience 3:35

18d ago3:35

3:35

👁️✨ Scientists have restored infrared vision using tellurium #nanowires implanted in the retina! 🧪 Mice and primates regained light sensitivity and behavioral vision. 🚀 A bold leap toward restoring sight without bulky tech. #VisionScience #NeuroTech #Retina #InnovationBy MasterMedFacts LLC

1
🥃 Alcohol and 🫀 Heart Disease: Dose, Debate, and Disease 5:12

19d ago5:12

5:12

🍷 Is a glass of wine a heart helper or hidden hazard? The 2025 AHA Statement says: ⚠️ Moderate = uncertain 🚫 Heavy = harmful 🫀 Risks include AFib, stroke, CAD, HF & sudden death 📊 New genetic studies challenge old myths. 👇 Know your limits. Rethink the drink. #CardioTwitter #MedEd #AHA2025By MasterMedFacts LLC

1
Revolutionizing Breastfeeding: A Conversation with Jenney Korasick, Co-Founder of Leche 41:07

19d ago41:07

41:07

In this empowering episode, Nazca Fontes sits down with Jenney Korasick, co-founder of Leche, to explore how one mom’s journey with breast milk oversupply turned into a revolutionary solution for breastfeeding families everywhere. From freeze-drying breast milk into a shelf-stable powder to launching a donor network that compensates and celebrates …

1
Dr RR Baliga's Philosophical Discourses: Patanjali (India, c. 200 BCE) – Compiler of Yoga Sutras 3:15

19d ago3:15

3:15

Patanjali, an ancient Indian sage, is credited with authoring foundational texts in Sanskrit grammar (Mahābhāṣya), yoga philosophy (Yoga Sutras), and possibly medicine (Patanjalatantra). Revered as a mystic and philosopher, his works laid the groundwork for classical yoga and linguistics, profoundly influencing Indian philosophical traditions. Thou…

1
🏁 From Chemo to Cardio: Prescribing Steps, May Save Lives 4:02

20d ago4:02

4:02

🏃‍♂️💪 New NEJM study shows structured exercise after chemo boosts survival in colon cancer patients! 📈 5-yr DFS: 80.3% vs 73.9% ❤️ 8-yr OS: 90.3% vs 83.2% 🧬 Fitness = longevity 👟 Time to prescribe steps, not just scripts? #Oncology #ExerciseIsMedicine #CHALLENGEtrialBy MasterMedFacts LLC

1
SGLT2 inhibitors: Safer Teens, Stronger Kidneys, Steadier Glucose 3:44

20d ago3:44

3:44

🚨 New trial alert! In youth with type 1 diabetes, adding #SGLT2i 💊 (dapagliflozin) to insulin: ✅ Reduced glomerular hyperfiltration ✅ Lowered HbA1c 📉 ✅ Boosted time-in-range ⏱️ 😌 Safe with DKA precautions in place 📄 #ATTEMPTTrial | @NatureMedicine 🔗 https://doi.org/10.1038/s41591-025-03723-6By MasterMedFacts LLC

1
Everything you need to know about EASA 23:57

20d ago23:57

23:57

This week Charli has LInda Raynes on to talk all about EASA! Check it out on their website Join us at EPIC, November 5th and 6th at San Jacinto College in Pasadena, TX Find us @EmpoweringPumps on Facebook, LinkedIn, Instagram and Twitter and using the hashtag #EmpoweringIndustryPodcast or via email [email protected]…

1
👁️ Eyeing the Risk: GLP-1 and Vision Loss 4:26

21d ago4:26

4:26

📉 New study alert! Patients with diabetes using GLP-1 receptor agonists had 2x higher risk of developing neovascular macular degeneration 😮 Longer use = greater risk 📈 Clinicians, keep an 👀 on ocular safety! #GLP1 #Diabetes #EyeHealth #nAMD #JAMAOphthalmologyBy MasterMedFacts LLC

1
🧲 The Iron Hand in Gender Fate 4:29

21d ago4:29

4:29

🧲 New twist in sex determination! Maternal iron levels shape whether XY embryos become male 🧬👶. Low iron ➡️ silenced Sry gene ➡️ female development 💡🧪. Epigenetics meets nutrition in utero—stay iron-clad, moms! #Epigenetics #IronMatters #SexDeterminationBy MasterMedFacts.com

1
Mini Organs (Gastruloids), Major Insights, Marvelous Science 🧫🔬✨ 5:49

22d ago5:49

5:49

🔬 New in @ScienceMagazine: Researchers grew mini human organs (gastruloids) with real blood vessels! ❤️🧠 Using stem cells + special cocktails, they modeled early heart & liver development in a dish. A leap for organoids & regenerative medicine! 🧪🧬 #Biotech #StemCells #OrganoidsBy MasterMedFacts LLC

1
🚫 Taurine ≠ Aging Clock: The Biomarker That Wasn’t 3:29

22d ago3:29

3:29

🧬 Is taurine the secret to youth? Not quite. 📈 New study shows taurine levels 📈 with age—especially in women. 🙅‍♂️ Not a reliable aging biomarker: too much variability, too many mixed signals. 🧠 Context matters. Supplement wisely. #Longevity #AgingResearch #Taurine #Science 🧪By MasterMedFacts LLC

1
🧠 From Burst Cells to Blocked Organs: The New Vascular Story 2:41

23d ago2:41

2:41

🧬 New vascular villain? It’s not always clots. 💥 Necroptosis of endothelial cells triggers red blood cell rupture. 🩸 Sticky RBC fragments form “endo-seals” that block blood flow—especially in COVID-19, stroke, and MI. 🎯 Targets? Think MLKL & complement, not just platelets. #MedTwitter #COVID19 #VascularBiology #Pathology…

1
🛡️ Warriors, Watchers & Worn-Outs: Mapping Immune Identity 4:58

23d ago4:58

4:58

🧬 New study reveals 4 stable #Immunotypes in healthy adults! Each with unique 🔥inflammatory, 🦠CMV-driven, 💧quiet, or 🔥aging-linked immune traits. They predict LPS response better than age or sex. Welcome to the era of immune fingerprinting! 🧪🧠 #PrecisionMedicine #Immunology #MultiomicsBy MasterMedFacts LLC

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