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PAULCAST

Paul Arun

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Welcome to "Business Chronicles", the podcast where we explore the fascinating stories behind some of the world's most iconic companies and places. A journey through the rich histories and intriguing tales of businesses and locations that have shaped our world.
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Formerly known as the Holmes Report‘s Echo Chamber, the PRovoke podcast brings insight and intelligence from the global PR industry. Featuring interviews, analysis and conversation, the weekly show is hosted by PRovoke Media editors Arun Sudhaman, Maja Pawinska Sims & Paul Holmes.
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This Life Science focused podcast brings together Xtalks editorial staff to share insights into the latest B2B industry news. Xtalks connects professionals in the life science, medical device, and food industries with useful content like webinars, job opening, articles and virtual meetings.
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In this episode, Ayesha speaks with Sumita Bhatta, MD, Vice President and Global Development Therapeutic Head of Rare Disease at Amgen. In the conversation, Dr. Bhatta shares insights on how large pharmaceutical companies like Amgen are approaching innovation and patient-centricity in the rare disease space. She also discusses the unique challenges…
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In this episode, Ayesha spoke with Paul Romness, MHP, chair and CEO of OS Therapies, a company developing novel immunotherapies for cancers like osteosarcoma and other solid tumors. Paul shares insights into OS Therapies’ lead program, the scientific rationale behind the company’s innovative immunotherapy approach and how the company is addressing …
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Golin chief AI officer Jeff Beringer joins the PRovoke Media podcast to discuss his vision for being a fully AI-integrated PR agency. If all goes as planned, Golin by 2026 will be the first fully AI-integrated PR firm, transforming everything from workflow and jobs to the nature of client relationships. In this episode of the PRovoke Media podcast,…
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In this episode, Ayesha spoke with Dr. Shaharyar Khan, co-founder and chief scientific officer at Rivus Pharmaceuticals. Rivus is developing a new class of investigational medicines called controlled metabolic accelerators (CMAs) for cardiometabolic diseases like diabetes, heart disease, heart failure and MASH by targeting obesity. Dr. Khan is an e…
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In this episode of The Hype Pod, join host Arun and Pastor Adam as they delve into the dynamic world of real estate with special guest Juan Ruan, President of Kinetic Real Estate. Discover how faith intersects with innovation and hear Juan's inspiring journey from a Chinese immigrant growing up in Mexico to becoming a successful real estate entrepr…
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In this episode, Ayesha spoke with Marc Hedrick, MD, MBA, president and CEO of Plus Therapeutics, a company focused on developing a novel class of targeted radiotherapeutics. Prior to heading Plus Therapeutics, Dr. Hedrick served in a number of executive leadership roles including president, CEO and director at Cytori Therapeutics, and president an…
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This year has already seen rapid and significant disruption in the media, policy and business landscape. Meanwhile, the increasing sophistication of disruptive technologies are leading to further confusion. Finn Partners partner David Krejci – a pioneer in media forensics, and an expert on misinformation, disruptive technologies, and bad faith acto…
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In this episode, Ayesha spoke with Carlos Martin, MBA, chief commercial operations and revenue officer at Rocket Pharmaceuticals, a company developing gene therapy cures for rare diseases through innovative science and platforms. Carlos joined Rocket in April 2021 and established the company’s early commercial strategy and infrastructure as Chief C…
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In this milestone 50th episode of the Hype Podcast, hosts Arun and Vance are joined by special guest Anto Patrex, founder and CEO of CosmicBrain AI. Anto shares his incredible journey from big tech AI to leading his own AI startup. The discussion delves into the exciting advancements in AI and quantum computing, covering topics such as robotics, th…
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In this episode, Ayesha spoke with Marshall Fordyce, MD, founder and CEO of Vera Therapeutics, a company focused on developing treatments for autoimmune diseases. Dr. Fordyce founded Vera in 2016 as an entrepreneur in residence at Kleiner Perkins Caufield and Byers, took the company public in 2021 and has advanced its lead molecule through a succes…
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In this episode, Ayesha spoke with Shalabh Gupta, MD, founder, chairman and CEO of Unicycive Therapeutics, a company focused on addressing unmet medical needs in renal diseases. Kidney diseases are a major global health concern. In the US, chronic kidney disease (CKD) affects more than one in seven individuals, and one in three adults with diabetes…
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Join us as we celebrate a major milestone — the 200th episode of the Xtalks Life Science Podcast! From groundbreaking biotech innovations to exclusive interviews with life science industry innovators and leaders, we've covered it all. Thank you for tuning in each week! We look forward to continuing to bring the latest and greatest across the pharma…
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In Episode 49, the hosts discuss their recent experiences, focusing on travel, restructuring, and scaling systems for future growth. They delve into an audacious vision for Vibe Church—aiming for 100 locations in 10 years—reflecting on the ambitious yet necessary nature of the goal. The conversation shifts to the state of the US economy, discussing…
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In this episode, Vera spoke with Ann Beliën, PhD, founder and CEO of Rejuvenate Biomed, a biotech company leveraging AI-driven platforms to develop therapies for age-related diseases and promote healthy aging. Rejuvenate Biomed is aiming to transform the treatment landscape for diseases such as sarcopenia, neuromuscular, metabolic and neurodegenera…
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In this episode, Ayesha spoke with Anthea Cherednichenko, MPH, MBA, Vice President, Hematology Franchise Head, Takeda, who discussed driving innovation in rare diseases through collaborations focused on better serving patients and their communities. Anthea has more than a decade of global experience serving the rare disease community, particularly …
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In this episode of the Hype Pod, Arun and Vance welcome new guest Pastor Luke Stewart, CEO of Adaptic Health and campus pastor at VIVE San Jose. This health-driven episode explores the flaws in the current healthcare system, highlighting Luke's unique journey from tech and product management to founding Adaptic Health. Luke shares his insights on i…
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FleishmanHillard's head of digital reputation for EMEA, Peter Wilson, joins Maja Pawinska Sims in the Markettiers studio to talk about the emergence of AI agents and the impact that automated processes, reports and analysis 'with the human in the loop' could have on many areas of PR practice, including public affairs and policy monitoring, and gett…
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Building on Zeno Group’s recent report on “Allies & Advocates,” which provides a new blueprint for civil society engagement in an increasingly polarized world, Paul Holmes sat down with Sarah Ogden, chief client officer for Zeno in London, and Georg Schmitt, former head of stakeholder engagement for the World Economic Forum and now a member of Zeno…
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In this episode, Ayesha spoke with Lee Honigberg, PhD, VP of Research & Development, ALZpath, a provider of diagnostic tools for Alzheimer’s disease. This includes a blood-based biomarker assay, called the ALZpathDx assay, which measures pTau217 in the blood. Prior to joining ALZpath, Dr. Honigberg was most recently Senior Director and Distinguishe…
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In this episode of the Hype Pod, Ps Adam welcomes Ps Andrew Thomas and Paul Lambess to the show as first time guests. Ps Andrew is a long time member and recently ordained Pastor at Vive church and Paul Lambess is the founder and director of Winarch Group and the newest Vive board member. Paul discusses his background, starting from psychology to f…
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In this episode, Vera speaks with Oded Kraft, Co-Founder, CEO and President of GrayMatters Health, a company transforming mental health care through evidence-based digital brain biomarker technology. Oded shares insights into GrayMatters Health’s mission to improve patient outcomes for mental health disorders like PTSD by leveraging their proprieta…
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In this episode, Ayesha spoke with Mario Marcondes, MD, PhD, VP Head of Clinical Development at Nektar Therapeutics, a company focused on the discovery and development of novel therapies for autoimmune disorders and cancer. Dr. Marcondes is a licensed and trained physician, specializing in oncology and immune oncology. He has more than 15 years of …
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In this episode of the Hype Pod, Arun & Vance are joined by returning guest Pastor Michelle to discuss the importance of civic engagement, emphasizing the necessity of local involvement to make meaningful change. They delve into Pastor Michelle's work with Hope Hanger and New Creation Homes, which provide essential support to low-income families an…
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In the first of a series of interviews with the leaders of agencies around the world, Paul Holmes sat down with Richard Edelman, CEO of Edelman. In a conversation that covered the firm’s history, the reasons it has remained committed to its independence, its Trust Barometer research, and the challenges Richard sees ahead as the competitive landscap…
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In this episode, Ayesha spoke with Sarah Averill Lott, MPH, CPH, Research Lead at Digital Medicine Society (DiMe) and Diane Stephenson, PhD, Executive Director at the Critical Path for Parkinson (CPP) at the Critical Path Institute. DiMe is a global non-profit and a professional home for digital medicine that aims to drive the broad adoption of dig…
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In the first episode of 2025, Pastor Adam, Vance and Arun discusses their holiday experiences, tech innovations, and plans for the new year. Vance reflects on his travels and culinary adventures, while Pastor Adam shares a low-key family holiday filled with spiritual growth and new hobbies like shooting and running with his daughters. They reveal t…
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In this episode, Ayesha spoke with Amit Etkin, Founder, President and CEO of Alto Neuroscience, a company developing precision treatments for neuropsychiatric conditions. Alto Neuroscience is focused on designing candidates that target core brain processes in patient populations not adequately treated by currently available medications. Alto is cur…
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In this episode, Vera spoke with Dr. Robert Den, Chief Medical Officer (CMO) of Alpha Tau Medical, a company developing cancer treatment with its highly potent alpha radiation technology. Dr. Den shared his journey to becoming CMO at Alpha Tau Medical and discussed the company’s mission to bring innovative cancer therapies to patients worldwide. Le…
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Research from UK agency Brands2Life found business-to-business marketers struggling to balance the immediate payoff of lead generation with the long-term imperative of building brand equity. PRovoke Media's Paul Holmes sat down with Emily Thomas of B2L and Coopervision senior global brand director Chris Carter to discuss how marketers can strike th…
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In this episode, Ayesha spoke with Judy Chou, PhD, CEO, President and Board member of AltruBio, a company developing first-in-class immunomodulators to target diseases of the immune system. AltruBio’s pipeline includes compounds being investigated for indications such as ulcerative colitis, psoriatic arthritis and acute graft vs. host disease. Prio…
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In the final episode of the year for the Hype Pod, host Arun Koshy, along with Pastor Adam and Vance Roush, reflect on the highlights of 2024 and discuss plans for 2025. The conversation covers a range of topics including the role and impact of Vive Church's Hype Network, the unique blend of faith and entrepreneurship, and exciting stories from var…
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In this week's episode of the Hype Pod, hosts Arun Koshy, Pastor Adam, and Vance Roush, tackle a range of topics, from Australia's proposed social media ban for under-16s and its implications on censorship and government control, to the influence of technology on youth and parenting approaches to social media. The conversation also touches upon the…
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Fine Lines founder Kat McGettigan and Goldbug founder Lara Gould join Maja Pawinska Sims on the PRovoke Podcast to talk about their career journeys and their experiences as female agency founders and leaders. The duo also dive into the Lonely Female Founders Club, which McGettigan recently launched to support women entrepreneurs in the PR industry …
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In this episode, Ayesha spoke with Jonathan Rigby, MBA, CEO of Sernova, a Canadian biotech company developing innovative cell therapy-based approaches for the management of type 1 diabetes. The company’s lead innovation is an implantable bio-hybrid organ pouch, which is currently in an ongoing Phase I/II clinical trial. An estimated 537 million peo…
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In this episode, Ayesha had a conversation with Lewis Bender, MBA, Founder, Chairman and CEO of Intensity Therapeutics, a biotech company developing first-in-class immune-based intratumorally injected cancer therapies. Intensity’s lead product candidate, INT230-6, is currently in human clinical studies for the treatment of refractory solid tumors, …
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In the first of a series of podcasts for and featuring chief communications officers, PRovoke Media founder discussed the various roles that CCOs play in supporting their executive leadership team at the World Economic Forum in Davos. Lenovo's Charlotte West discusses her experience at Davos earlier this year, while former WEF communications chief …
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In this episode, Ayesha spoke with John Yu, MD, CEO of Kairos Pharma, a company advancing therapies to overcome challenges in cancer drug resistance and immune suppression. Kairos is developing therapeutics that reverse cancer drug resistance in cancers such as prostate and lung cancer. The company’s lead candidate, ENV105, is an antibody targeting…
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In Episode 41 of the Hype Pod, Pastor Vance & Pastor Adam welcome distinguished guest Anthony Diaz, founder and CEO of the Go Project. The episode covers a wide range of topics from the booming crypto world post-election, the Go Project's mission to unlock abundance through real-world assets and blockchain technology, to Anthony's personal journey …
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In this episode, Ayesha spoke with Thomas Heineman, MD, PhD, Chief Medical Officer at Oncolytics Biotech, a company developing an oncolytic virus cancer therapeutic that is currently in clinical trials for indications including metastatic breast cancer and pancreatic cancer. Oncolytics is developing a first-in-class, nonpathogenic oncolytic virus a…
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In this episode, Ayesha spoke with AnnMarie Hipsley, DPT, PhD, CEO and founder of Ace Vision Group, an ophthalmic laser device company that is bringing touchless eye laser therapy to patients with age-related vision loss. Dr. Hipsley is a vision scientist, inventor, entrepreneur, author and speaker on ocular biomechanics and the biomechanical rejuv…
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Cyber breaches – like the recent DDOS attacks on archive.org and 23&Me – are making headlines more frequently, and the way they are handled in comms terms can have a lasting impact on corporate reputation. In this episode of the PRovoke podcast, Maja Pawinska Sims is joined by Flora Haslam, European technology practice leader at Finn Partners, Rich…
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Dive into the post-election analysis with the Hype Pod team in this special episode! Join the conversation as Pastors Adam, Vance and Michelle Stewart dissect the implications of the latest election, discuss the future of the Republican and Democratic parties, and share their thoughts on the key moments that defined the night. From election watch p…
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In the wake of our PRovokeGlobal Summit, Paul Holmes got together with Drew Warren and Rachel Caggiano from Ogilvy to discuss the dominant themes of the event, from the future of purpose in a politicized environment to the impact of AI on newsrooms and PR agencies—as well as Ogilvy’s big night at the Global SABRE Awards, where it was crowned Global…
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In this episode, Ayesha spoke with Shaheen Lakhan, MD, PhD, Chief Medical and Scientific Officer, Click Therapeutics, a company focused on developing software as prescription medical treatments for people with unmet medical needs. Click Therapeutics is specifically developing Digital Therapeutics, which involve the delivery of prescription treatmen…
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In this episode of the PRovoke Media podcast, Maja Pawinska Sims is joined by Richard Smith, co-founder and CEO of fintech Payen, and MikeWorldWide director Conrad Arnavutian, to talk about humanising B2B technology, purpose- and values-driven B2B communications, and how brands and communicators in this sector can navigate the future of sustainabil…
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Join Arun Koshy and Pastor Adam in an inspiring conversation with Johannes Escudero, a renowned pastor and the founder and CEO of the Coalition for Renewable Gas. In this episode, they delve into Johannes’ entrepreneurial journey, the crucial developments in the renewable energy sector, and the innovative mission behind the Hype Network. Listen as …
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