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Live to 150? David Sinclair on why we age — and why he thinks we don't have to

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Manage episode 483959840 series 2456057
Content provided by ABC Radio and ABC listen. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by ABC Radio and ABC listen or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

What if we could turn back time on our biological clock and slow down — even reverse — aging? High profile Harvard scientist David Sinclair is co-author of the New York Times bestseller Lifespan: Why We Age and Why We Don’t Have To. His lab’s work is as ambitious as it is controversial. He wants to radically change the way we live our lives — and push at the boundary of what it means to be human. Professor Sinclair joins Big Ideas host Natasha Mitchell at the 2025 World Science Festival Brisbane.

Speaker

David A SinclairProfessor of GeneticsAuthor (with Matthew D. LaPlante) of Lifespan: Why We Age and Why We Don’t Have To (Atria Book, 2019)Blavatnik Institute, Harvard Medical SchoolPaul F. Glenn Center for Biology of Aging Research Harvard University

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271 episodes

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Manage episode 483959840 series 2456057
Content provided by ABC Radio and ABC listen. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by ABC Radio and ABC listen or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

What if we could turn back time on our biological clock and slow down — even reverse — aging? High profile Harvard scientist David Sinclair is co-author of the New York Times bestseller Lifespan: Why We Age and Why We Don’t Have To. His lab’s work is as ambitious as it is controversial. He wants to radically change the way we live our lives — and push at the boundary of what it means to be human. Professor Sinclair joins Big Ideas host Natasha Mitchell at the 2025 World Science Festival Brisbane.

Speaker

David A SinclairProfessor of GeneticsAuthor (with Matthew D. LaPlante) of Lifespan: Why We Age and Why We Don’t Have To (Atria Book, 2019)Blavatnik Institute, Harvard Medical SchoolPaul F. Glenn Center for Biology of Aging Research Harvard University

  continue reading

271 episodes

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Food is essential to human life, but are we taking it for granted? Popular chef, writer and broadcaster Adam Liaw is an advocate for good food for everyone. He takes us on a journey through the history and science of food, and its place in our societies, economies and cultures throughout time, arguing that food should play a central role in government policy making. The 2025 Hugh Stretton Oration was recorded at the University of Adelaide on 14 May 2025. Speakers Adam Liaw Cook, writer, broadcaster Alison Coates Professor of Human Nutrition, University of South Australia…
 
Books on tyrants, dictators, and authoritarian leaders are suddenly bestsellers again as we all try to make sense of the tilt towards tyrannical leadership around the world, the mass compliance it commands, and its use of terror, fear, and often violence, to govern. Two of Australia's leading scholars on China and the Soviet Union, Linda Jaivin (author of BOMBARD THE HEADQUARTERS! The Cultural Revolution in China) and Sheila Fitzpatrick (author of The Death of Stalin) join Big Ideas host Natasha Mitchell to consider two 20th Century tyrants whose legacies live on today. Speakers Linda Jaivin Author and China specialistAssociate, Australian Centre on China in the World , Australian National University Professor Sheila Fitzpatrick Historian of modern Russia and the Soviet UnionProfessor, Australian Catholic University and Honorary Professor, University of Sydney This event was presented by Readings Books with Black Inc Books , with thanks to events producer Christine Gordon.…
 
At a time when governments are retreating from promises of progress for First Nations people, what can be achieved through legal and human rights mechanisms? The 2025 Mabo Oration was recorded at the Cairns Performing Arts Centre on 30 May 2025, with thanks to the Queensland Human Rights Commission and QPAC. Speakers Katie Kiss Aboriginal and Torres Strait islander Social Justice Commissioner Gail MaboVisual Artist, Artistic Director, Choreographer, Writer and Actor…
 
Doctor Who has acted as a mirror to more than six decades of social, technological and cultural change. It's been able to evolve and adapt more radically than any other fiction. Why we are so addicted to fiction, and why does this wonderful wandering time traveller mean so much to so many. This talk was provided by the York Festival of Ideas . The Festival is led by the University of York, UK. Speaker John Higgs Author of Exterminate/Regenerate: The Story of Doctor Who (Weidenfeld & Nicolson 2025)…
 
Acclaimed British author Jeanette Winterson argues that 200 years ago, Mary Shelley's Frankenstein, was a message in a bottle, a prophesy, of today's AI revolution. This conversation was recorded at the Sydney Writers' Festival , in partnership with the University of New South Wales's Centre for Ideas on 21 May 2025. Speakers Jeanette Winterson Author, 12 Bytes: How artificial intelligence will change the way we live and love, Oranges are not the only fruit, and many moreProfessor of New Writing at the University of Manchester Toby Walsh (host)Author, The Shortest History of AI: Six ideas to understand artificial intelligence today and moreChief Scientist of AI, University of New South WalesFellow, Australian Academy of Science…
 
Citizen Jury is ABC Radio National's experiment in citizen-led democracy. The ingredients? A gnarly issue + a jury of citizens = conversations + ideas for solutions + a public event to share them. Join Big Ideas presenter Natasha Mitchell in Dubbo, NSW for our first Citizen Jury. We all want electricity at the flick of a switch, but who bears the brunt of making that happen? Join citizens who live in Australia's first official Renewable Energy Zone or REZ where millions of solar panels, hundreds of wind turbines, large storage batteries, and high voltage transmission lines are being rolled out over a 20,000 square kilometre area.But the scale and pace are sowing seeds of division in the community. Some see benefits, some see potential harms.What they think could be done better or differently? What can the rest of Australia learn from their experiences about the energy transition? Thank you to the Dubbo Regional Council and the Western Plains Cultural Centre teams for their support for this event. Speakers Adam Ryan (Citizen Jury member)Wiradjuri man and fatherTeacher, Wellington Correctional CentreCouncillor, Dubbo Regional Council (but not representing Council on this panel) Grant Gjessing (Citizen Jury member)Business owner, Strait-Up Cranes and DiggingPresident, Business Mudgee Linda Gant (Citizen Jury member)Cattle and sheep farmer with her husband for 40 years in Cassilis, NSW.Member, Cassilis District Development Group Member, Liverpool Range Wind Farm Community Consultation Committee Tony Inder (Citizen Jury member)6th generation merino wool farmer and 'solar sheep grazier' in Wellington, NSW Andrew Bray ( participated in Citizen Jury meetings)National director, ReAlliance (Australian Renewable Energy Alliance) Janine Young Energy and Water Ombudsman NSW (EWON) Ash Albury Executive Director, Planning and Communities, EnergyCo Peter Bennett Executive Project Director, EnergyCo And thank you to the various community members and other stakeholders in attendance who participated in the event. Representatives from ACEREZ and Squadron Energy were also in attendance. Thanks to cattle and sheep farmer Simon Barton from Wellington, NSW and Michael Bullock, Manager of Bodangora wind farm (Iberdrola) for their participation in a social media story. Particular thanks to ABC Western Plains Chief of Staff Nick Lowther and rural reporters Claudia Sullivan and Catherine James for their support. Further information Central-West Orana Renewable Energy Zone Parliamentary inquiry: Impact of Renewable Energy Zones (REZ) on rural and regional communities and industries in NSW Australian Energy Infrastructure Commissioner (AEIC): Community Engagement Review (in relation to Renewable Energy Infrastructure developments).This review was undertaken by the former Commissioner Andrew Dyer, who is now a Professorial Fellow at Monash University.…
 
John Maynard Keynes was an economist whose dreams went beyond balance sheets and into political ideas and cultural movements. He advised world leaders during world wars, witnessed the great depression first hand and counted himself as one of the Bloomsbury group, a set of London's most influential writers and intellectuals like Virginia Woolf. This discussion from CUNY Graduate Center is an in depth look at the life of JohnMaynard Keynes and explores his influence on 20th century economics and politics. Speakers Zachary Carter Journalist and author who wrote the award-winning Keynes biography "The Price of Peace: money, democracy, and the life of John Maynard Keynes" Paul Krugman Nobel Prize-winning economist, longtime former columnist for The New York Times, and distinguished professor of Economics at the CUNY Graduate Center…
 
Photojournalism can define a moment, a movement, an era or even a whole generation. It can lift a weary spirit, move opinions, or change the way we view the world. Three of Australia's best photojournalists tell the stories behind some of Australia's most iconic photographs, and reflect on the profession's past, present and future. This event was recorded at the National Library of Australia on 27 May 2025. Speakers Lorrie Graham Photojournalist Rick Stevens Photojournalist Mike Bowers (host)Presenter, Talking Pictures, Insiders, ABC TVPhotographer at large for The New DailyCurator, Fit to Print: Defining Moments from the Fairfax Photo Archive , National Library of Australia Further information: Paul Keating 'Ray Bans' 1993 - by Lorrie Graham Bob Hawke election campaign launch 1983 - by Lorrie Graham Gough Whitlam gets a kiss from Dorothy Scott 1972 - by Rick Stevens Fit to Print: Defining Moments from the Fairfax Photo Archive at the National Library of Australia until 20 July 2025…
 
Australia faces many big challenges, but is our democracy up to the job of solving these, or are we experiencing a decision deadlock? One process that could help governments meet the moment is known as citizen jury or assembly, where a cross section of ordinary people deliberate together over a thorny policy issue, then provide advice. How do these work, are they effective, and should they play a more central role in Australia's democracy? The session, The Place for Citizens Assemblies in Australia — where do they best fit? was recorded at Policy without Politics conference , hosted by Citizen Assemblies for South Australia , at the Woodville Town Hall in Adelaide on 14 June 2025. Speakers Jay Weatherill Director of Democracy, McKinnonFormer South Australian Premier (2011 to 2018) Simon Birmingham Former South Australian Liberal Senator (2007 to 2025) Emma Fletcher Co-CEO, Democracy Co Elizabeth Farrelly (host)Writer, columnist, critic, academic, broadcasterFormer councillor, City of SydneyDirector, Better Cities InitiativeAuthor, Bubberland; the Dangers of Happiness and Killing Sydney; the fight for a city's soul…
 
We bathe in the amniotic fluid our mother's womb. Our cells are full of water. For Walbanja woman, artist, educator and researcher Dr Jodi Edwards, this ocean-within intimately connects her to the ocean she grew up with on Sea Country. From saving the Sea kin to sensing the Gaia imperative — join Jodi with Big Ideas host Natasha Mitchell, and also hear from award-winning author James Bradley and CEO-turned-climate-action advocate Mark Rowland as they explore why the ocean's function is so vital to your own. This event was hosted by the 2025 Ocean Lovers Festival at Bondi Beach as part of its Ocean Talks program. Dr Jodi Edwards Creative arts practitioner, story sharer, educator, researcherAssociate professor and Vice Chancellor Indigenous Research Fellow National Centre for Ocean Resources & Security University of Wollongong. James Bradley Author of Deep Water: The World in the Ocean (2024) Mark Rowland Consultant, systems-thinker, climate-action advocateGAIA Imperative Thanks to Lorna Parry and Carolyn Grant from the Ocean Lovers Festival. Further information Unbroken whispers: the ripples connecting sea kin A project run by Dr Jodi Edwards and Gumbaynggirr woman and ecologist Dr Chels Marshall…
 
The Kurdish poet Behrouz Boochani and the Australian writer Arnold Zable explore the power of friendship as an act of resistance, nourishment and healing. This event was recorded with the Faculty of Arts at the University of Melbourne 29 April 2025. Speakers Behrouz Boochani Kurdish-Iranian writer, journalist, scholar, cultural advocate, filmmaker, and public advocate for human rightsAuthor, No Friend But the Mountains: Writing from Manus Prison, and Freedom Only FreedomAdjunct Associate Professor in Social Sciences at the University of New South Wales, McGeorge Fellow, University of Melbourne Arnold Zable Author, Jewels and Ashes, Café Scheherazade, The Fig Tree,The Watermill and moreWinner, Australia Council Award for a Lifetime Achievement in Literature, 2021 Nikos Papastergiadis (host)Cultural critic, essayist and author, John Berger and Me: A Migrant's EyeFormer Director of the Research Unit in Public Cultures at the University of Melbourne…
 
In October 2023, Australians voted no to a Voice to Parliament for First Nations people. In this panel from the 2025 Melbourne Writers Festival , four speakers who saw the campaign up close discuss what went wrong, and even whether the whole endeavour was worth it. Ultimately they’re all trying to answer the question, where do we go from here? Speakers Thomas Mayo Kaurareg Aboriginal and Kalkalgal, Erubamle Torres Strait Islander, author, activist and 'yes' campaigner Ben Abbatangelo Gunaikurnai and Wotjobaluk journalist Nardi Simpson Yuwaalaraay artist, musician and author Daniel Browning (host)Bundjalung and Kullilli man, Professor of Indigenous Cultural and Creative Industries at University of Sydney and former ABC arts journalist…
 
What would religion, work, sex or technology look like if we lived in a truly feminist world? In a perfect world would the messy stuff make the cut? Or would stuff that makes us human be left in the real world? Join two big thinkers who unpack it all as they build their own feminist utopia in this episode of Big Ideas. This was a live philosophy event presented in London at the Sophia Club, from the creators of Aeon and Psyche magazines. You can find out more about the series at sophiaclub.co . Speakers Chine McDonald Author of Unmaking Mary: Shattering the Myth of Perfect Motherhood and director of religion and society think tank Theos Kate Devlin Professor of artificial intelligence and society at King’s College London and author of Turned On: Science, Sex and Robots Sally Davies (host)Writer and contributing editor at Aeon magazine…
 
Dark tourism is increasingly popular. Sites of suffering like old gaols, asylums, orphanages hold a certain allure. Can we honour their dark heart and histories, whilst also re-imagining their future? Should some 'traumascapes' be left untouched so the scars of the past are never forgotten, or can we turn them into happier settings with sensitivity? How do designers, developers, and historians tread such tricky terrain? This event was organised by Open House Melbourne and held in the Old Melbourne Gaol during Melbourne Design Week 2025. Speakers Dr Sue Hodges Heritage interpretations specialistManaging director, international consultancy SHP (Sue Hodges Productions Pty Ltd) Erwin Taal Senior AssociateInternational landscape architect and urban design studio ASPECT Studios…
 
Language is always evolving, and reflecting back to us our society, politics and identity. From profanity, to personal pronouns, to the politics of translation and cultural appropriation, why do we use the words we do? This event was recorded at the University of Sydney. Speakers John McWhorter Associate Professor of English and Comparative Literature, Colombia UniversityAuthor, Pronoun Trouble: The Story of Us in Seven Little Words, Nine Nasty Words: English in the Gutter, Woke Racism: How a New Religion Has Betrayed Black America and moreColumnist, New York TimesHost, Lexicon Valley podcast Nick Enfield Professor of Linguistics, University of Sydney Further information: How a Plane to Australia Took Me to '90s Oakland - New York Times, 20 March, 2025…
 
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