Jamie McGuire: What If the Real Problem Isn’t Your Skin... But Your Protocol?

Biohacking Beauty: The Anti-Aging Skincare Podcast

What if your breakouts, fine lines, and melasma weren’t about finding the “perfect” product, but fixing what’s happening under the surface?

In this episode, we’re joined by Jamie McGuire, functional aesthetician and founder of Jamie Ann Aesthetics, to explore what truly personalized skincare looks like—and why most routines miss the mark.

We unpack how internal stress, diet, hormones, and nervous system dysfunction show up on your face, why you shouldn’t chase quick fixes, and how to build an anti-aging protocol that actually works. We also discuss the most common skincare mistakes keeping people inflamed, irritated, and stuck, and the real reason exfoliation might be accelerating skin aging.

You'll also learn about the products, peptides, and treatments Jamie actually recommends (and avoids), plus her top recovery tools after explant surgery—and why she believes peptides outperform most supplements.

Jamie McGuire is a licensed esthetician and gut‑health nutrition specialist with over a decade of experience. Her bold protocols have earned her a devoted online following among those seeking skin transformation that goes far beyond surface treatments.

We Also Discuss:

01:43 – Why Jamie doesn’t need to see your skin to know what’s wrong

04:52 – The one thing she tells clients to fix before skincare

11:05 – Why most men hate skincare—and what actually works for them

20:43 – The truth about anti-aging: what to use in your 30s vs. 50s

26:50 – Why exfoliating too much is aging your skin

39:04 – Are your products secretly making your skin worse?

59:50 – Her explant recovery: what worked, what didn’t, and why peptides came first

Learn more about:

Young Goose

• Use code PODCAST10 to get 10% off your first purchase, and if you’re a returning customer use the code PODCAST5 to get 5% off at https://www.younggoose.com/
• Instagram: @young_goose_skincare

Jamie McGuire

Website: https://jamieanne.co/

Instagram:@jamieanneaesthetics