Episode 52 - Scraping the barrel | Approach to thrombocytopenia

Bloody Minded

Are you a platelet that has been conjugated to an antibody? Sequestered in a spleen? Diluted out by too much saline? Had your precious gold stolen from you? Then you might be entitled to thrombensation! Listen to this episode to learn how we can help YOU approach thrombocytopenia.

TIMESTAMPS

2:23 - Striking gold where you least expect it
4:40 - Definition of thrombocytopaenia
8:06 - What do platelets do?
9:22 - History for thrombocytopaenia
12:20 - Exam for thrombocytopaenia
18:03 - Artefactual thrombocytopaenia
21:28 - Decreased platelet production
24:46 - Increased platelet consumption
24:55 - ITP
27:43 - APLS
28:15 - HIT
29:45 - Thrombotic microangiopathies
32:09 - Redistribution/Sequestration
33:41 - Dilutional causes
34:35 - Pregnancy-Related Causes
39:23 - Investigations
42:05 - Platelet Transfusion Thresholds
44:36 - Take Home Messages

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Chapters

1. Episode 52 - Scraping the barrel | Approach to thrombocytopenia (00:00:00)

2. Striking gold where you least expect it (00:02:23)

3. Definition of thrombocytopaenia (00:04:40)

4. What do platelets do? (00:08:06)

5. History for thrombocytopaenia (00:09:22)

6. Exam for thrombocytopaenia (00:12:20)

7. Artefactual thrombocytopaenia (00:18:03)

8. Decreased platelet production (00:21:28)

9. Increased platelet consumption (00:24:46)

10. ITP (00:24:55)

11. APLS (00:27:43)

12. HIT (00:28:15)

13. Thrombotic microangiopathies (00:29:45)

14. Redistribution/Sequestration (00:32:09)

15. Dilutional causes (00:33:41)

16. Pregnancy-Related Causes (00:34:05)

17. Investigations (00:39:14)

18. Platelet Transfusion Thresholds (00:42:00)

19. Take Home Messages (00:44:25)