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The HRT Conversation
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The HRT Conversation
Rage, Relief, and the Hormone Rollercoaster
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Rage, Relief, and the Hormone Rollercoaster
Are you navigating perimenopause or menopause and wondering what the fork is happening to your body? You’re not alone. In this powerful episode, Karen and Lisa sit down with hormone specialist Naomi Major to have the honest, no-BS conversation every woman over 40 deserves about hormone replacement therapy (HRT), testosterone, estrogen, and progesterone.
Naomi breaks down the science behind hormone imbalance, explains why most women are being gaslit by their doctors, and shares how HRT—especially testosterone therapy—is changing lives (and saving relationships). We bust myths about breast cancer risk, dive into bioidentical hormones, and explore how to advocate for better care when your provider just isn’t cutting it.
Whether you're struggling with sleep, energy, mood swings, libido, weight gain—or you're just curious about what’s actually going on during midlife—this episode is your go-to guide for reclaiming your health and stepping into your “second spring.
💥 Topics Covered:
What is HRT and how does it work?
Why testosterone isn’t just for men
The truth about bioidentical hormones
What your doctor probably doesn’t know about menopause
How hormone therapy can strengthen bones, boost libido, and support long-term wellness
How to advocate for yourself in a broken healthcare system
🎧 If you're a woman in your 40s, 50s, or 60s who's ready to stop suffering in silence and start living vibrantly, this episode is for you.
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🎧Show NotesWant Answers to Your Hormone Questions?
Naomi Major, our expert guest on this episode, is offering free 15-minute informational chats to help you get clarity on your unique hormone needs. No pressure, just answers.
✨ Book your call: Schedule with Naomi Major
📧 Email Naomi directly: [email protected]
Naomi Major
MLS (ASCP)CM
CHIEF OPERATING OFFICER/DIRECTOR OF NUTRITION
Integrated Health Alliance
Instagram Profile
Hormone Replacement Therapy - we tried to find a good factual link to explain our topic but literally anything we could find, even from Class A sources like the Mayo Clinic and the Cleveland Clinic, only talk about “female hormones”, recommend it only during menopause, and label testosterone therapy in women risky. Awesome. Pretty much backs up everything we talked about on this episode. Please reach out to Naomi for any questions you might have.
Episode 12: Menopause: True Lies
Episode 44: Menopause Meets Ayurveda
Dr. Rachel Rubin
Polycystic Ovary Syndrome (PCOS)
Controversy with pregnant mare urine farms
"The New Menopause: Navigating Your Path Through Hormonal Change with Purpose, Power, and Facts" by Mary Claire Haver, MD
"MenuPause: Five Unique Eating Plans to Break Through Your Weight Loss Plateau and Improve Mood, Sleep, and Hot Flashes"
By Dr. Anna Cabeca
Digging Into the Truth About Testosterone Replacement Therapy (TRT) for Women
As Naomi shares in this episode, the data on TRT for women is shockingly limited—and the bias is real. But there is good research out there if you know where to look. These links offer critical insights into the benefits, safety, and the frustrating gap in care for women seeking hormone support.
Here are the key articles Naomi recommends for diving deeper:
📌 The Gold Standard Overview:
Androgen Therapy in Women with Testosterone Insufficiency: Looking Back and Looking Ahead – A must-read on clinical benefits and the systemic bias still impacting women’s access.
📌 Consensus Guidelines:
Global Consensus Position Statement on the Use of Testosterone Therapy for Women
ISSWSH Clinical Guidelines for HSDD Treatment with Testosterone
📌 Research on Safety & Breast Cancer:
Reduced Breast Cancer Incidence in Women Treated with Testosterone or Testosterone with Anastrozole – Yes, you read that right. Long-term studies showing breast protection.
📌 Other Valuable Reads:
A Personal Perspective on Testosterone Therapy in Women (2022)
Testosterone Therapy in Women: Myths and Misconceptions (2013)
Testosterone in Women—The Clinical Significance
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Need help remembering what we talked about? Join the Pod Squad (our email list!) for direct links, show notes, and more midlife goodness delivered to your inbox. 💌
💬 Takeaways — What Do YOU Think?We want to hear from you! Drop your thoughts in the comments, or send us an email at [email protected]. Whether it's a story, a laugh, or a “yep, been there”—we love hearing how our episodes land with you.
📲 Stay ConnectedFollow, like, and join the conversation:
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Got a question, idea, or just want to say hi? We’re all ears.
Email us anytime: [email protected]
Connect with your hosts:
✨ Karen Shatafian – www.karenshatafian.com
✨ Lisa Corricello-McDowell – www.nextlevellifewithlisa.com
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