Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
Player FM - Internet Radio Done Right
Checked 1M ago
Added nine years ago
Content provided by Taylor & Francis Group and Francis Group. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Taylor & Francis Group and Francis Group or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.
Similar to Future Science Group
Come dive into one of the curiously delightful conversations overheard at National Geographic’s headquarters, as we follow explorers, photographers, and scientists to the edges of our big, weird, beautiful world. Hosted by Peter Gwin and Amy Briggs.
…
continue reading
Unseeable forces control human behavior and shape our ideas, beliefs, and assumptions. Invisibilia—Latin for invisible things—fuses narrative storytelling with science that will make you see your own life differently.
…
continue reading
Science Friction's latest series is: Cooked. We dig into food science pickles. Why are studies showing that ice cream could be good for you? Do we really need as many electrolytes as the internet says? And why are people feeling good on the carnivore diet? Nutrition and food scientist Dr Emma Beckett takes us through what the evidence says about foods like meat, ice cream and potatoes — and unpicks why nutrition studies can be so conflicting and confusing. All six episodes of Cooked are avai ...
…
continue reading
DNA science. Artificial intelligence. Smartphones and 3D printers. Science and technology have transformed the world we live in. But how did we get here? It wasn’t by accident. Well, sometimes it was. It was also the result of hard work, teamwork, and competition. And incredibly surprising moments. Hosted by bestselling author Steven Johnson (“How We Got To Now”), American Innovations uses immersive scenes to tell the stories of the scientists, engineers, and ordinary people behind the great ...
…
continue reading
We humans could have a bright future ahead of us that lasts billions of years. But we have to survive the next 200 years first. Join Josh Clark of Stuff You Should Know for a 10-episode deep dive that explores the future of humanity and finds dangers we have never encountered before lurking just ahead. And if we humans are alone in the universe, if we don't survive intelligent life dies out with us too.
…
continue reading
Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future
…
continue reading
Join Dr Karl Kruszelnicki, Lucy Smith and their scientific guests, with a bunch of curious triple j listeners for a weekly injection of science, myth-bashing and answers!
…
continue reading
Interviews with Anthropologists about their New Books Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/anthropology
…
continue reading
Welcome to Curiosity Weekly from Discovery, hosted by Dr. Samantha Yammine. Once a week, we’ll bring you the latest and greatest in scientific discoveries and break down the details so that you don’t need a PhD to understand it. From neuroscience to climate tech to AI and genetics, no subject is off-limits. Join Sam as she interviews expert guests and investigates the research guiding some of the most exciting scientific breakthroughs affecting our world today. Hosted on Acast. See acast.com ...
…
continue reading
Player FM - Podcast App
Go offline with the Player FM app!
Go offline with the Player FM app!
))
Daily Deals
The need for HRMS for quantitation of ADCs vs. QQQ: an interview with Megan Cooley
Manage episode 460395649 series 1258384
Content provided by Taylor & Francis Group and Francis Group. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Taylor & Francis Group and Francis Group or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.
In this episode, we sit down with Megan Cooley, Associate Director of Bioanalytical Services at ICON (KS, USA), to explore the cutting-edge world of antibody-drug conjugate (ADC) quantitation using high-resolution mass spectrometry (HRMS). Megan delves into the capabilities of Triple Quadrupole and Time-of-Flight mass spectrometry, offering her expert insights into whether HRMS is essential for ADC PK studies. We also tackle the challenges and limitations of HRMS in ADC quantitation and discuss the potential for AI to create more specific and stable ADCs. Finally, Megan highlights ICON’s extensive experience with large molecule applications and their innovative approach to supporting complex LC–MS analyses.
…
continue reading
290 episodes
ShareManage episode 460395649 series 1258384
Content provided by Taylor & Francis Group and Francis Group. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Taylor & Francis Group and Francis Group or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.
In this episode, we sit down with Megan Cooley, Associate Director of Bioanalytical Services at ICON (KS, USA), to explore the cutting-edge world of antibody-drug conjugate (ADC) quantitation using high-resolution mass spectrometry (HRMS). Megan delves into the capabilities of Triple Quadrupole and Time-of-Flight mass spectrometry, offering her expert insights into whether HRMS is essential for ADC PK studies. We also tackle the challenges and limitations of HRMS in ADC quantitation and discuss the potential for AI to create more specific and stable ADCs. Finally, Megan highlights ICON’s extensive experience with large molecule applications and their innovative approach to supporting complex LC–MS analyses.
…
continue reading
290 episodes
All episodes
×
F
Future Science Group
1 Unveiling bioanalytical datasets for the successful development of ADCs 19:03
19:03 
Play Later 
Play Later 
Lists 
Like 
Liked19:03
Play Later Play Later Lists Like LikedUnveiling bioanalytical datasets for the successful development of ADCs
F
Future Science Group
1 Bridging science and safety: exploring toxicology studies and regulatory requirements 10:50
10:50 Play Later Play Later Lists Like Liked10:50
Play Later Play Later Lists Like LikedBridging science and safety: exploring toxicology studies and regulatory requirements
F
Future Science Group
1 Cell therapies for autoimmune diseases: a podcast with Lindsay Davies 13:17
13:17 Play Later Play Later Lists Like Liked13:17
Play Later Play Later Lists Like LikedThis International Women’s Day, we’re joined by Lindsay Davies, Chief Scientific Officer at NextCell Pharma (Stockholm, Sweden), to discuss the evolving role of cell therapies in treating autoimmune diseases. In this podcast, Davies breaks down the science behind NextCell’s mesenchymal stromal cell therapy for type 1 diabetes and explores how these cells could be applied to other autoimmune conditions. She emphasizes the importance of tailoring cell therapies based on disease type, stage and patient profile to achieve the best outcomes. The conversation also highlights how growing evidence of sex-related differences will could increasingly shape decisions in the development and testing of cell therapies.…
F
Future Science Group
1 The use of GenAI in bioanalysis: an interview with Priyata Kalra 28:30
28:30 Play Later Play Later Lists Like Liked28:30
Play Later Play Later Lists Like LikedDuring the American Association of Pharmaceutical Scientists (AAPS) PharmSci 360 2024 conference, Bioanalysis Zone caught up with industry experts across numerous disciplines to discuss their involvement with AAPS and their research. In this interview, we spoke to Priyata Kalra about her talk on the use of GenAI within biomedicine.…
F
Future Science Group
1 The need for HRMS for quantitation of ADCs vs. QQQ: an interview with Megan Cooley 21:35
21:35 Play Later Play Later Lists Like Liked21:35
Play Later Play Later Lists Like LikedIn this episode, we sit down with Megan Cooley, Associate Director of Bioanalytical Services at ICON (KS, USA), to explore the cutting-edge world of antibody-drug conjugate (ADC) quantitation using high-resolution mass spectrometry (HRMS). Megan delves into the capabilities of Triple Quadrupole and Time-of-Flight mass spectrometry, offering her expert insights into whether HRMS is essential for ADC PK studies. We also tackle the challenges and limitations of HRMS in ADC quantitation and discuss the potential for AI to create more specific and stable ADCs. Finally, Megan highlights ICON’s extensive experience with large molecule applications and their innovative approach to supporting complex LC–MS analyses.…
F
Future Science Group
1 How can medical device regulation catch up with innovation? 12:36
12:36 Play Later Play Later Lists Like Liked12:36
Play Later Play Later Lists Like LikedIn this interview, we discuss the potential of AI in increasing healthcare system efficiency, how medical devices are making procedures less invasive and what those working in the field of medical devices can do to help regulation catch up with innovation.
F
Future Science Group
1 The new frontier: assessing efficacy and safety of CGTs using biomarkers 24:21
24:21 Play Later Play Later Lists Like Liked24:21
Play Later Play Later Lists Like LikedIn the sixth episode of The new frontier podcast, we're joined by Catherine Vrentas, Life Sciences Lead at Booz Allen Hamilton (VA, USA). Cathy explains how biomarkers can be used to predict the therapeutic outcome and efficacy of CGTs and the biomarkers in particular that have shown strong predictive value. We delve into the common challenges of working with biomarkers in CGTs and how biomarker kits can be adapted for CGT work.…
F
Future Science Group
Carlon Fitzpatrick AI Summit by Taylor & Francis Group
F
Future Science Group
1 Challenges and solutions in monitoring assay performance for vaccine development 18:26
18:26 Play Later Play Later Lists Like Liked18:26
Play Later Play Later Lists Like LikedChallenges and solutions in monitoring assay performance for vaccine development: an interview with Atul Chaudhari
F
Future Science Group
1 ADA detection and characterization for immunogenicity testing: insights from ICON's Lindsay Denhoff 11:13
11:13 Play Later Play Later Lists Like Liked11:13
Play Later Play Later Lists Like LikedWe caught up with Principal Scientist Lindsay Denhoff (ICON; Dublin, Ireland) to discuss immunogenicity considerations for therapeutic proteins and the current analytical methodologies for detecting and characterizing anti-drug antibodies (ADAs). Lindsay shares some industry best practices for achieving high-quality ADA assays, as well as some of the advantages and limitations of singlicate ADA analysis compared with alternative techniques. We finish the interview with a look to the future where Lindsay discusses the emerging trends she's spotted in the field of immunogenicity and offers her predictions for how they may shape the future of therapeutic protein development.…
F
Future Science Group
In this Tech Blast episode supported by Sartorius (Göttingen, Germany), we speak with David Apiyo – Manager of Applications Development at Sartorius (MN, USA) – about epitope binning, why it's performed and the best ways to conduct it. Plus, learn more about Sartorius' biolayer interferometry platforms and their application in epitope binning.…
F
Future Science Group
1 Using the Gyrolab® platform for oligo quantification: an interview with John Chappell 6:35
6:35 Play Later Play Later Lists Like Liked6:35
Play Later Play Later Lists Like LikedIn this interview, we spoke to John Chappell, Senior Global Scientific Support Manager at Gyros Protein Technologies (Uppsala, Sweden) about his experience working with the Gyrolab platform for oligonucleotide assays. John discusses the advantages of using Gyrolab for oligo quantification in biological fluids and shares his thoughts on the next steps for these assays.…
F
Future Science Group
1 The new frontier: qPCR vs ddPCR for cell and gene therapies 15:41
15:41 Play Later Play Later Lists Like Liked15:41
Play Later Play Later Lists Like LikedIn the fifth episode of The New Frontier podcast, we're joined by Paul Byrne, Senior Director of Genomics from ProtaGene (MA, USA). Paul describes his experience working with qPCR vs digital and digital droplet PCR assays and advises on their pros and cons, as well as when it's best to use each. We discuss how these assays can be optimized for cell and gene therapy targets and get a peek into the tips and tricks he's picked up over his 30 years of experience.…
F
Future Science Group
1 The new frontier: using LC–MS/MS for quantitative assays to support gene therapies 13:33
13:33 Play Later Play Later Lists Like Liked13:33
Play Later Play Later Lists Like LikedIn this episode of The New Frontier podcast, we're joined by Daniel Schulz-Jander, Senior Director of Mass spectrometry Bioanalysis at QPS Netherlands (Groningen). Daniel explains how he uses immune-precipitation and immunoaffinity LC–MS techniques for his work relating to macromolecular pharmaceuticals like gene therapies, as well as their benefits and challenges. Daniel also covers bottom-up, middle-down and top-down approaches and their suitability for his work in clinical support versus research and discovery.…
F
Future Science Group
1 Breaking down barriers for women in tech: an interview with Tina Marshall 16:15
16:15 Play Later Play Later Lists Like Liked16:15
Play Later Play Later Lists Like LikedBreaking down barriers for women in tech: an interview with Tina Marshall by Taylor & Francis Group
Welcome to Player FM!
Player FM is scanning the web for high-quality podcasts for you to enjoy right now. It's the best podcast app and works on Android, iPhone, and the web. Signup to sync subscriptions across devices.
Daily Deals
Similar to Future Science Group
Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
…
continue reading
Come dive into one of the curiously delightful conversations overheard at National Geographic’s headquarters, as we follow explorers, photographers, and scientists to the edges of our big, weird, beautiful world. Hosted by Peter Gwin and Amy Briggs.
…
continue reading
Unseeable forces control human behavior and shape our ideas, beliefs, and assumptions. Invisibilia—Latin for invisible things—fuses narrative storytelling with science that will make you see your own life differently.
…
continue reading
Science Friction's latest series is: Cooked. We dig into food science pickles. Why are studies showing that ice cream could be good for you? Do we really need as many electrolytes as the internet says? And why are people feeling good on the carnivore diet? Nutrition and food scientist Dr Emma Beckett takes us through what the evidence says about foods like meat, ice cream and potatoes — and unpicks why nutrition studies can be so conflicting and confusing. All six episodes of Cooked are avai ...
…
continue reading
DNA science. Artificial intelligence. Smartphones and 3D printers. Science and technology have transformed the world we live in. But how did we get here? It wasn’t by accident. Well, sometimes it was. It was also the result of hard work, teamwork, and competition. And incredibly surprising moments. Hosted by bestselling author Steven Johnson (“How We Got To Now”), American Innovations uses immersive scenes to tell the stories of the scientists, engineers, and ordinary people behind the great ...
…
continue reading
We humans could have a bright future ahead of us that lasts billions of years. But we have to survive the next 200 years first. Join Josh Clark of Stuff You Should Know for a 10-episode deep dive that explores the future of humanity and finds dangers we have never encountered before lurking just ahead. And if we humans are alone in the universe, if we don't survive intelligent life dies out with us too.
…
continue reading
Professor Jim Al-Khalili talks to leading scientists about their life and work, finding out what inspires and motivates them and asking what their discoveries might do for us in the future
…
continue reading
Join Dr Karl Kruszelnicki, Lucy Smith and their scientific guests, with a bunch of curious triple j listeners for a weekly injection of science, myth-bashing and answers!
…
continue reading
Interviews with Anthropologists about their New Books Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/anthropology
…
continue reading
Welcome to Curiosity Weekly from Discovery, hosted by Dr. Samantha Yammine. Once a week, we’ll bring you the latest and greatest in scientific discoveries and break down the details so that you don’t need a PhD to understand it. From neuroscience to climate tech to AI and genetics, no subject is off-limits. Join Sam as she interviews expert guests and investigates the research guiding some of the most exciting scientific breakthroughs affecting our world today. Hosted on Acast. See acast.com ...
…
continue reading
Player FM - Podcast App
Go offline with the Player FM app!
Go offline with the Player FM app!
