Nootropics beyond caffeine: Power up your brain with Lisa Costa-Bir and Dr Greg Kelly

FX Medicine Podcast Central

In this episode of fx Medicine by BioCeuticals, host Lisa Costa-Bir speaks with naturopathic physician and nootropic expert Dr Greg Kelly about the evolving role of nootropics in supporting cognitive performance. Greg shares how plant-based and nutritional compounds - including bacopa (Bacopa monnieri), saffron (Crocus sativus), gotu kola (Centella asiatica), alpinia (Alpinia galanga), L-theanine, and nicotinamide riboside - can enhance focus, memory, motivation, and mental energy. The conversation explores how these agents work through key pathways such as acetylcholine signalling, neuroplasticity, and mitochondrial function. Greg also unpacks the concept of brain resource depletion, the impact of modern distractions, and why nootropics are just as relevant for healthy individuals as they are for those with cognitive challenges. He offers practical guidance on stacking, cycling, and how to support non-responders by returning to foundational naturopathic principles like sleep, nutrition, and stress management. This episode is packed with practical, science-backed takeaways for anyone looking to optimise focus, memory, motivation, and overall cognitive performance - whether in clinical practice or everyday life. Covered in this episode: (00:57) Welcome Greg Kelly (02:02) What are nootropics? (05:05) Why do we become depleted? (12:23) L-theanine (17:51) Bacopa (24:25) Saffron (30:01) Gingko (33:17) Alpinia & Ginger (37:29) Gotu Kola (40:29) Nicotinamide riboside (44:19) Chronic stress and brain damage (46:45) Are nootropics essential for some patients? (51:30) Safety issues (55:22) Thanks and final remarks Find today's transcript and show notes here: https://www.bioceuticals.com.au/education/podcasts/nootropics-beyond-caffeine-power-up-your-brain-with-lisa-costa-bir-and-dr-greg-kelly Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: https://login.bioceuticals.com.au ***DISCLAIMER: The information provided on fx Medicine by BioCeuticals is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.***