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Unveiling Evidence-Based Medicine Plus and Mechanistic Reasoning

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Manage episode 483628796 series 3608409
Content provided by UK CEiRSI | InSilicoUK. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by UK CEiRSI | InSilicoUK or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

What is Evidence-Based Medicine Plus? This podcast episode explores the transformative power of computational modelling and simulated clinical trials in medical innovation. Discover the significance of evidence-based medicine (EBM) and evidential pluralism, emphasising the role of mechanistic evidence alongside traditional studies. Join us as we delve into compelling examples like mobile phone radiation and ACE inhibitors, highlighting how these insights enhance the external validity of treatments. Perfect for researchers and regulators alike, or anyone interested in the evolving landscape of medicine.

Sources:

Russo F, Williamson J. Epistemic causality and evidence-based medicine. Hist Philos Life Sci. 2011;33(4):563-81.
Parkkinen, V.-P., Wallmann, C., Wilde, M., Clarke, B., Illari, P., Kelly, M. P., Norell, C., Russo, F., Shaw, B., & Williamson, J. (Eds.). (2023). Evaluating Evidence of Mechanisms in Medicine: Principles and Procedures. Oxford University Press.

  continue reading

41 episodes

Artwork
iconShare
 
Manage episode 483628796 series 3608409
Content provided by UK CEiRSI | InSilicoUK. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by UK CEiRSI | InSilicoUK or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

What is Evidence-Based Medicine Plus? This podcast episode explores the transformative power of computational modelling and simulated clinical trials in medical innovation. Discover the significance of evidence-based medicine (EBM) and evidential pluralism, emphasising the role of mechanistic evidence alongside traditional studies. Join us as we delve into compelling examples like mobile phone radiation and ACE inhibitors, highlighting how these insights enhance the external validity of treatments. Perfect for researchers and regulators alike, or anyone interested in the evolving landscape of medicine.

Sources:

Russo F, Williamson J. Epistemic causality and evidence-based medicine. Hist Philos Life Sci. 2011;33(4):563-81.
Parkkinen, V.-P., Wallmann, C., Wilde, M., Clarke, B., Illari, P., Kelly, M. P., Norell, C., Russo, F., Shaw, B., & Williamson, J. (Eds.). (2023). Evaluating Evidence of Mechanisms in Medicine: Principles and Procedures. Oxford University Press.

  continue reading

41 episodes

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