Most of us have gotten at least a little emotional at some point recently. It’s natural. But why do we have emotions and how much should we pay attention to them on any given day? Can we learn to skillfully choose which emotions to listen to and which ones to just let move on by? In More Than A Feeling, the latest podcast from Ten Percent Happier, host Saleem Reshamwala goes on a real life quest to find the answers to these questions. He’ll experiment with neuroscientists, dive into stories ...
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Content provided by Jody Marks, MSN, AGACNP-BC, FNP-BC, Jody Marks, and MSN. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Jody Marks, MSN, AGACNP-BC, FNP-BC, Jody Marks, and MSN or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.
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A New(-ish) Antacid Medication
Manage episode 437593486 series 3476336
Content provided by Jody Marks, MSN, AGACNP-BC, FNP-BC, Jody Marks, and MSN. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Jody Marks, MSN, AGACNP-BC, FNP-BC, Jody Marks, and MSN or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.
The new PCAB Voquenza (vonoprazan) is being marketed as a superior alternative to PPI therapy for acid-related conditions (GERD with or without erosive esophagitis, H. pylori eradication). Are these two mechanisms of action really that different? Jody investigates.
References:
1) Prescriber information: https://www.phathompharma.com/wp-content/uploads/VOQUEZNA-tablets-Prescriber-Information.pdf
2) György Miklós Buzás, Dual acid-pump blocking as novel therapeutic approach to treatment of acid-related diseases, Medical Hypotheses, Volume 187, 2024, 111338, ISSN 0306-9877, https://doi.org/10.1016/j.mehy.2024.111338.
3) Katzka DA, Kahrilas PJ. Potassium-Competitive Acid Blocker Suppression of Gastric Acid in Erosive Esophagitis: Is Stronger and Longer Better? Gastroenterology. 2023 Jan;164(1):14-15. doi: 10.1053/j.gastro.2022.10.022. Epub 2022 Oct 28. PMID: 36341738.
4) Shin JM, Sachs G. Pharmacology of proton pump inhibitors. Curr Gastroenterol Rep. 2008 Dec;10(6):528-34. doi: 10.1007/s11894-008-0098-4. PMID: 19006606; PMCID: PMC2855237.
5) Simadibrata DM, Syam AF, Lee YY. A comparison of efficacy and safety of potassium-competitive acid blocker and proton pump inhibitor in gastric acid-related diseases: A systematic review and meta-analysis. J Gastroenterol Hepatol. 2022 Dec;37(12):2217-2228. doi: 10.1111/jgh.16017. Epub 2022 Oct 26. PMID: 36181401; PMCID: PMC10092067.
6) Oshima T, Miwa H. Potent Potassium-competitive Acid Blockers: A New Era for the Treatment of Acid-related Diseases. J Neurogastroenterol Motil. 2018 Jul 30;24(3):334-344. doi: 10.5056/jnm18029. PMID: 29739175; PMCID: PMC6034668
80 episodes
Share
Manage episode 437593486 series 3476336
Content provided by Jody Marks, MSN, AGACNP-BC, FNP-BC, Jody Marks, and MSN. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Jody Marks, MSN, AGACNP-BC, FNP-BC, Jody Marks, and MSN or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.
The new PCAB Voquenza (vonoprazan) is being marketed as a superior alternative to PPI therapy for acid-related conditions (GERD with or without erosive esophagitis, H. pylori eradication). Are these two mechanisms of action really that different? Jody investigates.
References:
1) Prescriber information: https://www.phathompharma.com/wp-content/uploads/VOQUEZNA-tablets-Prescriber-Information.pdf
2) György Miklós Buzás, Dual acid-pump blocking as novel therapeutic approach to treatment of acid-related diseases, Medical Hypotheses, Volume 187, 2024, 111338, ISSN 0306-9877, https://doi.org/10.1016/j.mehy.2024.111338.
3) Katzka DA, Kahrilas PJ. Potassium-Competitive Acid Blocker Suppression of Gastric Acid in Erosive Esophagitis: Is Stronger and Longer Better? Gastroenterology. 2023 Jan;164(1):14-15. doi: 10.1053/j.gastro.2022.10.022. Epub 2022 Oct 28. PMID: 36341738.
4) Shin JM, Sachs G. Pharmacology of proton pump inhibitors. Curr Gastroenterol Rep. 2008 Dec;10(6):528-34. doi: 10.1007/s11894-008-0098-4. PMID: 19006606; PMCID: PMC2855237.
5) Simadibrata DM, Syam AF, Lee YY. A comparison of efficacy and safety of potassium-competitive acid blocker and proton pump inhibitor in gastric acid-related diseases: A systematic review and meta-analysis. J Gastroenterol Hepatol. 2022 Dec;37(12):2217-2228. doi: 10.1111/jgh.16017. Epub 2022 Oct 26. PMID: 36181401; PMCID: PMC10092067.
6) Oshima T, Miwa H. Potent Potassium-competitive Acid Blockers: A New Era for the Treatment of Acid-related Diseases. J Neurogastroenterol Motil. 2018 Jul 30;24(3):334-344. doi: 10.5056/jnm18029. PMID: 29739175; PMCID: PMC6034668
80 episodes
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Most of us have gotten at least a little emotional at some point recently. It’s natural. But why do we have emotions and how much should we pay attention to them on any given day? Can we learn to skillfully choose which emotions to listen to and which ones to just let move on by? In More Than A Feeling, the latest podcast from Ten Percent Happier, host Saleem Reshamwala goes on a real life quest to find the answers to these questions. He’ll experiment with neuroscientists, dive into stories ...
…
continue reading
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…
continue reading
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continue reading
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Dream fans....WE ARE BACK! We're reimagining The Dream as a weekly interview podcast with guests and segments about, I don't know.... whatever we want? Don't worry! We'll still be focused on the "American Dream" and all the assholes that make it infinitely harder to achieve. We'll just have a bit more freedom in how we present it. Hosted on Acast. See acast.com/privacy for more information.
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