Antidepressant Insights

Medication Talk

Listen in as our expert panel discusses practical considerations for starting and optimizing antidepressants for treating depression and anxiety. You’ll listen to panelists cover various aspects of antidepressant use, such as serotonin syndrome, QT prolongation, and weight gain concerns.

Special guest(s):

• Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP
  • Director of Pharmacy and Residency Programs, New York State Office of Mental Health
  • State University of New York at Buffalo School of Pharmacy and Pharmaceutical Sciences
• Sarah E. Grady, PharmD, BCPS, BCPP
  • Professor, Drake University College of Pharmacy and Health Sciences
  • Clinical Pharmacist, Inpatient Behavioral Health Unit, Broadlawns Medical Center

You’ll also hear practical advice from TRC’s Editorial Advisory Board member:

• Craig D. Williams, PharmD, FNLA, BCPS
  • Clinical Professor of Pharmacy Practice
  • Oregon Health and Science University

None of the speakers have anything to disclose.

This podcast is an excerpt from one of TRC’s monthly live CE webinars, the full webinar originally aired in May 2025.

TRC Healthcare offers CE credit for this podcast. Log in to your Pharmacist’s Letter, Pharmacy Technician’s Letter,or Prescriber Insights account and look for the title of this podcast in the list of available CE courses.

Claim Credit

The clinical resources related to this podcast are part of a subscription to Pharmacist’s Letter, Pharmacy Technician’s Letter, and Prescriber Insights.

• Clinical Resources:
  • Choosing Antidepressants
  • Switching Antidepressants
  • Combining and Augmenting Antidepressants
  • Pharmacotherapy of Anxiety Disorders in Adults

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Chapters

1. Introduction (00:00:00)

2. CE Information (00:02:06)

3. Evaluating Antidepressant Options (00:02:38)

4. Starting an Antidepressant (00:05:17)

5. Serotonin Syndrome (00:11:45)

6. QT Prolongation (00:16:39)

7. Hyponatremia / Low Sodium (00:20:10)

8. Seizure Risk / Bupropion (00:21:09)

9. Weight Gain (00:22:12)

10. Optimizing Treatment (00:24:21)

11. Duration of Treatment (00:30:38)

12. PRN Antidepressants (00:35:02)

13. Conclusion (00:37:09)