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67 | A hypothesis is a liability

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Manage episode 455813658 series 2912199
Content provided by Itai Yanai & Martin Lercher, Itai Yanai, and Martin Lercher. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Itai Yanai & Martin Lercher, Itai Yanai, and Martin Lercher or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

In this episode, Itai and Martin delve into the interplay between hypothesis-driven and exploratory research, drawing on insights from past guests of the Night Science Podcast. They discuss how being focused on a single hypothesis can prevent us from making discoveries, while emphasizing the value of open-ended exploratory analyses—often dismissed as “fishing expeditions.” The episode also examines the risks inherent to both approaches: hypothesis-driven Day Science may overlook key insights, while exploratory Night Science risks being misled by randomness.
This episode was supported by Research Theory (researchtheory.org).
For more information about Night Science, visit https://www.biomedcentral.com/collections/night-science .

  continue reading

Chapters

1. Introduction (00:00:00)

2. Inhabiting the data (00:02:55)

3. Digging outliers (00:05:31)

4. Fishing expeditions (00:09:45)

5. Thanking our sponsors (00:15:18)

6. Triangulation in exploratory analysis (00:15:54)

7. Exploration can thrive at small scales (00:22:01)

8. Looking for patterns (00:27:23)

9. The data-hypothesis conversation (00:31:00)

10. Explore with caution (00:34:13)

11. Credits (00:39:04)

76 episodes

Artwork

67 | A hypothesis is a liability

Night Science

31 subscribers

published

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Manage episode 455813658 series 2912199
Content provided by Itai Yanai & Martin Lercher, Itai Yanai, and Martin Lercher. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Itai Yanai & Martin Lercher, Itai Yanai, and Martin Lercher or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

In this episode, Itai and Martin delve into the interplay between hypothesis-driven and exploratory research, drawing on insights from past guests of the Night Science Podcast. They discuss how being focused on a single hypothesis can prevent us from making discoveries, while emphasizing the value of open-ended exploratory analyses—often dismissed as “fishing expeditions.” The episode also examines the risks inherent to both approaches: hypothesis-driven Day Science may overlook key insights, while exploratory Night Science risks being misled by randomness.
This episode was supported by Research Theory (researchtheory.org).
For more information about Night Science, visit https://www.biomedcentral.com/collections/night-science .

  continue reading

Chapters

1. Introduction (00:00:00)

2. Inhabiting the data (00:02:55)

3. Digging outliers (00:05:31)

4. Fishing expeditions (00:09:45)

5. Thanking our sponsors (00:15:18)

6. Triangulation in exploratory analysis (00:15:54)

7. Exploration can thrive at small scales (00:22:01)

8. Looking for patterns (00:27:23)

9. The data-hypothesis conversation (00:31:00)

10. Explore with caution (00:34:13)

11. Credits (00:39:04)

76 episodes

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