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Non-linear Elimination and Dosage Regimen
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Manage episode 155209105 series 1149979
Content provided by David Bourne. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by David Bourne or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.
For drugs which exhibit non-linear metabolism within their therapeutic range can be difficult to dose. Small changes in dose can result in larger changes in concentration. Using average values for parameters can be a good start but better results can be achieved with therapeutic drug monitoring. Analysis of TDM data can by use of equations or graphical methods. Both types of approaches are described in this tutorial.
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21 episodes
M4V•Episode home
Manage episode 155209105 series 1149979
Content provided by David Bourne. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by David Bourne or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.
For drugs which exhibit non-linear metabolism within their therapeutic range can be difficult to dose. Small changes in dose can result in larger changes in concentration. Using average values for parameters can be a good start but better results can be achieved with therapeutic drug monitoring. Analysis of TDM data can by use of equations or graphical methods. Both types of approaches are described in this tutorial.
…
continue reading
21 episodes
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