E165: Dr. Gemma Eminowicz - Treating Gynaecological Cancers with MR-Linac and Brachytherapy

Rad Chat

Trigger Warning: cancer, gynaecological cancer, death and dying, gender based violence, mental health and brachytherapy.

Episode 165: Part of the education and workforce development (series 57).

Description: In this powerful episode, Naman Julka-Anderson and Jo McNamara sit down with Dr. Gemma Eminowicz to hear about her work in utilising MR-Linac for gynaecological cancer.

Dr. Gemma Eminowicz MBChB, MRCP, FRCR, MD(Res) is a consultant clinical oncologist and brachytherapy lead treating gynaecological cancers at University College London Hospital (UCLH). She is also an honorary clinical associate professor at University College London (UCL), chair of the GEC-ESTRO gynae working group, member of ESTRO gynae focus group, organiser of gyn-SMART webinars and principle investigator on many systemic therapy clinical trials including at a UK level (eg Keynote B21). She has published 26 oncology papers, 8 as first author and multiple book chapters. She has been heavily involved in the practice changing INTERLACE trial from radiotherapy quality assurance to analysis of final results and dissemination of primary and secondary outcome data. She remains active within ESTRO, ESGO, BGCS and GTG-UK and strives to improve patient care through multidisciplinary treatments focusing on systemic therapy and high quality radiotherapy.

CPD Reflection Points:

1. Read about the types of gynaecological cancers, along with signs and symptoms of each: https://eveappeal.org.uk/information-and-advice/gynaecological-cancers/.
2. Consider how you could support people who have to have brachytherapy treatment.

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Links from the Episode:

• Dr. Gemma Eminowicz https://www.uclh.nhs.uk/our-services/find-consultant/dr-gemma-eminowicz
• GEC-ESTRO gynaecology committee: https://www.estro.org/About/ESTRO-Organisation-Structure/Committees/GEC-ESTRO-Committee
• ESTRO Gynaecology focus group: https://www.estro.org/About/ESTRO-Organisation-Structure/Focus-Groups/Gynaecology
• GYN-Smart webinars: https://sites.google.com/view/gyn-smart
• Keynote B21: https://www.annalsofoncology.org/article/S0923-7534(24)03822-5/fulltext
• INTERLACe trial: https://www.ctc.ucl.ac.uk/TrialDetails.aspx?Trial=89
• MR-Linac treatment Genesis Care: https://www.genesiscare.com/uk/treatment/radiotherapy/mr-linac

Research links from the Episode:

• Creutzberg C, Kim JW, Eminowicz G et al. The Gynecologic Cancer InterGroup(GCIG) consensus recommendations for clinical research in Endometrial Cancer. Lancet oncology September 2024.
• Sarwar A, Eminowicz G. Radiotherapy induced ureteric stenosis in locally advanced cervical cancer: A review of current evidence. Brachytherapy, 2024,ISSN 1538-4721, https://doi.org/10.1016/j.brachy.2024.03.002.
• Mirza MR, RUBY investigators. Dostarlimab for Primary Advanced or Recurrent Endometrial Cancer. N Engl J Med. 2023 Jun 8;388(23):2145-2158.
• Gaze MN, Smeulders N, Ackwerh R, Allen C, Bal N, Boutros M, Cho A, Eminowicz G, Gill E, Fittall MW, Humphries PD, Lim P, Mushtaq I, Nguyen T, Peet C, Pendse D, Polhill S, Rees H, Sands G, Shankar A, Slater O, Sullivan T, Hoskin PJA National Referral Service for Paediatric Brachytherapy: An Evolving Practice and Outcomes Over 13 Years. Clin Oncol(R Coll Radiol). 2022 Dec 30:S0936-6555(22)00609-4. doi: 10.1016/j.clon.2022.12.008. Online ahead of print.
• Sarwar A, Lalli N, Eminowicz G. Ureter dose optimization during image guided brachytherapy for cervical cancer. Brachytherapy. 2022 Apr 11:S1538-4721(22)00035-6.

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Credits: Music and jingle credits: Dr. Ben Potts and Adam Cooke.