LLMs For Everyone In Health And Life Sciences? The Health Pulse podcast

22:28

The work of delivering innovative therapies to patients must be done well and quickly. This became the leadership mantra for Nevine Zariffa, former Head of Biometrics and Information Sciences at AstraZeneca, following her personal battle with cancer. Diagnosed with chronic myeloid leukemia (CML) at 33, Zariffa's cancer has been in remission for 25 years thanks to an investigational drug she received through a compassionate use clinical trial. In this episode, Zariffa joins Alex to discuss the evolution of AI in the pharmaceutical industry. She emphasizes the importance of a strong connection between business leaders and data scientists in scaling AI projects. Tune in to discover Zariffa’s formula for effective change management and her insights on the future of AI in pharma and health tech.…

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From Research to Patient Care: Bridging the Gap 34:47

5 weeks ago34:47

34:47

What is a learning health care system, and how close are we to achieving it? According to Dr. Marc Berger, we have a long way to go, but there’s plenty of cause for optimism. Berger is a physician, scientist and researcher who spent much of his career in clinical and outcomes research in the pharmaceutical industry. Now semiretired and consulting, Berger recently joined host Alex Maiersperger on the podcast. He explained that a true learning health care system removes the barriers between research and patient care. This goal requires digitization and integration of all health care data in a responsible way to better inform decision making, and it will need computing and analysis power the world has yet to master. It’s a big task, but Berger’s message is clear: If we continue to make progress, stay humble about what we don’t yet know and are kind to one another, we’ll get there.…

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People, Technology and the Journey to a Healthier Tomorrow 26:17

33 weeks ago26:17

26:17

Lita Sands, Managing Director of Life Sciences at Deloitte, is passionate about how people and technology come together to create a healthier future. In this episode, Sands explains to Host Alex Maiersperger why life sciences organizations must strengthen their relationships with health care and ensure data and analytics form the backbone of their companies. According to Sands, technology is easy, while change management and the partnership between business and IT represent critical challenges. When it comes to generative AI, Sands advises life sciences organizations to focus on what she calls “no regrets bets,” emphasizing the importance of a person in the loop. Tune in to learn more.…

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Teaching Medical Students About Equity and AI 28:36

37 weeks ago28:36

28:36

Dr. James Hildreth, MD, PhD, President and CEO of Meharry Medical College, is a passionate leader speaking about health equity, the power of AI in medicine and how aspiring physicians can be supported throughout their studies. In this episode, Hildreth speaks about the influence of social determinants of health-on-health equity and offers advice on reducing inequities. Host Alex Maiersperger and Hildreth discuss impactful AI use cases in health care, such as the documentation of notes from patient and physician interactions, so that physicians can focus their time on the patient. Hildreth explains that AI can accelerate the discovery of disease causes, drugs and new interventions and that representation matters so that the data sets from genome sequencing also include people of African ancestry to ensure discoveries are representative of the diverse population and interventions are working. Lastly, Hildreth shares his leadership experience in making medical school more affordable for aspiring doctors and the importance of exposure to technology and AI from an early age.…

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Unlocking the Potential of AI in Health Care: A Vision for Change 28:32

40 weeks ago28:32

28:32

Dr. Onyi Daniel, Sinai Health System Board Member and former Vice President for Data and Analytics Strategy at Highmark Health, is a passionate health tech leader who speaks about change management, AI use cases, health equity and the importance of responsible AI. In this episode, Daniel shares her leadership experience and explains why it is incremental that health care leadership can articulate the vision for technological change and define the associated value. Host Alex Maiersperger and Daniel discuss emerging AI use cases in the health care industry, such as ambient listening or code generation, which can improve productivity and experience and reduce burnout. Despite the infinite opportunities that new technologies bring, Daniel emphasizes the importance of upstream data collection, data quality, governance and inclusion, ensuring models and outcomes represent diverse populations to enhance health equity.…

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AI, Imaging and the Race to Develop Therapies 27:02

43 weeks ago27:02

27:02

Artificial intelligence holds tremendous potential for advancing clinical research. On this episode of The Health Pulse podcast, host Alex Maiersperger connects with Dr. Greg Goldmacher, Associate Vice President for Clinical Research and Head of Clinical Imaging and Pathology at Merck. Goldmacher identifies AI’s ability to automate advanced image measurements and improve insight into disease biology to support clinical development. From a clinical radiology perspective, AI has the potential to improve diagnosis and opportunistic screening for earlier disease detection. Goldmacher leaves us with his thoughts on the synergies needed within life sciences organizations to bring clinical development and data science teams together and move AI projects from idea to execution.…

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Improving Health for All of Us 24:28

45 weeks ago24:28

24:28

In a world where your zip code can have as great an impact on your health as your genetic code, how can we create a healthier future for everyone? On this episode of The Health Pulse, we hear from Dr. Joyonna Gamble-George, a neuroscientist at the Yale School of Public Health, and Dr. Karriem Watson, Chief Engagement Officer of the National Institutes of Health’s All of Us Research Program, about how the All of Us program deepens our understanding of social determinants of health and addresses health care disparities. The All of Us Research Program is a diverse, representative database composed of health data from more than 1 million people. The program has 10,000 registered users of different backgrounds and skill sets and helps them better understand and solve health challenges. Tune in to hear these health care research leaders reflect on the impact of precision medicine and how AI and other cutting-edge technology are advancing research and closing the digital divide.…

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A Conversation With an Oncology Legend 33:01

48 weeks ago33:01

33:01

Dr. Otis Brawley, Bloomberg Distinguished Professor of oncology and epidemiology at Johns Hopkins University, is passionate about cancer research, prevention and high-quality cancer care. He served as Chief Medical and Scientific Officer and Executive Vice President of the American Cancer Society from 2007 to 2018 and has published over 200 scientific articles. In this episode, Dr. Brawley speaks about the impact of socioeconomic factors on cancer rates. Smoking, obesity and poverty are leading causes of cancer in the United States. With cancer rates rising, Dr. Brawley emphasizes the importance of prevention and risk reduction, including healthy lifestyle choices such as regular exercise and a healthy diet. Dr. Brawley is passionate about reducing cancer care disparities and saving lives with accessible, high-quality care, including appropriate screening, diagnostics and treatments. Having the correct data and technology in place can help to identify high-risk individuals and plan interventions early to prevent diseases. Lastly, Dr. Brawley shares valuable insights on carcinogens and practical tips on how to prevent cancer.…

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Empowering Cancer Patients With Lifesaving Information 21:56

51 weeks ago21:56

21:56

Dr. Maya Said, Founder and CEO of Outcomes4Me, aims to empower cancer patients worldwide to be proactive about their care with information and technology. On this episode of The Health Pulse podcast, Said shares how a personal health scare illuminated for her how overwhelmed cancer patients feel when they face understanding their diagnosis and treatment options, finding the best providers and clinical trials, managing treatments and costs, and navigating their lives and relationships during treatment. The experience inspired her to launch the platform Outcomes4Me, which uses data and AI to help cancer patients become more informed and connected to improve their outcomes – at no cost. Tune in to learn more about the role of data in addressing disparities in cancer care and how generative AI is poised to revolutionize treatment.…

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Health Care Interoperability and AI in Action 22:37

1 year ago22:37

22:37

Dr. Michael von Wagner, Chief Medical Informatics Officer at University Hospital Frankfurt and a pioneer in interoperability, speaks about the importance of a seamless data exchange for personalized patient treatments and efficient health care systems. On this episode, Dr. von Wagner joins Alex Maiersperger to discuss health data standardization, new regulations, and two pioneering data and AI projects at University Hospital Frankfurt. A team of experts came together at the hospital to integrate data from different sources into a dashboard that monitors trends in the development of antibiotic resistance, enabling optimization of treatments. In another project, they collaborate with another major university hospital and general practitioners to combine research and clinical data on rare diseases to help GPs with evidence-based diagnoses. Dr. von Wagner is optimistic about the future of health care with AI-based solutions for clinical decision support, but also explains why risks and opportunities need to be evaluated carefully. He emphasizes that the interoperability, flexibility and scalability of AI-based solutions are key to a successful future.…

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What to Really Expect From Generative AI 33:08

1 year ago33:08

33:08

GenAI is rapidly making the once impossible possible. On this episode of The Health Pulse, SAS’ AI Product Strategy Advisor Marinela Profi chats with Host Alex Maiersperger about just how fast the needle is moving and what we can and cannot likely expect large language models (LLMs) to solve anytime soon. Some of the GenAI use cases Profi is most excited about are in the health care space, helping providers accelerate tasks and glean valuable information for diagnostic and care decisions. She shares a balanced perspective on the possibilities and caution required when applying generative technology in health care and life sciences, highlighting the importance of explainable AI and a human in the loop.…

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LLMs for everyone in health and life sciences? 17:28

1 year ago17:28

17:28

There is no shortage of interest around large language models (LLMs) in the health care and life sciences space. Are organizations able to successfully operationalize LLMs in a cost-efficient, regulatory-compliant and ethical manner? On this episode of The Health Pulse podcast, SAS Global Medical Director Dr. Steve Kearney and host Alex Maiersperger discuss key considerations around the application of LLMs. Explore how organizations are improving data interoperability and converging across health care and life sciences – thus positively impacting patient outcomes and experiences.…

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Accelerating Health Equity With Technology and Trust 18:39

2 years ago18:39

18:39

Health equity is a hot topic in health care, and Dr. Pooja Mittal speaks about key success components, including the importance of trust, technology and strong relationships with communities. Bringing health stakeholders and community members together is crucial to building trust and providing culturally relevant care that drives better health outcomes. From a young age, Dr. Mittal realized that health care is not equitable, and challenging environmental conditions cause higher disease rates. With a mission to reduce health disparities, Dr. Mittal became a physician and Chief Health Equity Officer at Health Net. She believes technology is key to making care more equitable and supporting patients from historically disadvantaged communities, as it enables access to data to better understand needs, access to telehealth, enabling patients to receive care remotely and access to culturally sensitive technology, supporting unique needs.…

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SAS opens up about open source in life sciences 20:14

2 years ago20:14

20:14

There’s no such thing as a free lunch, but there are many benefits to a balanced diet. That’s SAS’ philosophy around embracing and extending open source as explained by life sciences leaders Mark Lambrecht and Matt Becker on this episode of the Health Pulse Podcast. To keep up with the staggering pace of change, life sciences organizations need cutting-edge analytics and the flexibility to use different programming languages. Tune in for a candid conversation about the pros and cons of open source and commercial software and the importance of the statistical computing environment (SCE) in clinical research.…

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The Impact of Diagnostics on Health Care 22:23

2 years ago22:23

22:23

Bryan Vaughn is passionate about bending the cost curve in health care. As Senior Vice President, Hospitals and Health Systems at Labcorp, he focuses on the role of diagnostics in delivering better, more affordable care. On this episode, Vaughn notes that impactful partnerships across the health care ecosystem can help drive the cost of critical diagnostics down, creating a win for all stakeholders. When it comes to analytics, he is excited to see Labcorp’s wealth of health data empowering and informing patients and their doctors today—as well as the potential for predictive analytics and Artificial Intelligence (AI) to improve health outcomes in the future.…

The Health Pulse

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The Health Pulse S3E4: The End of Global Supply Chains? 31:59

3 years ago31:59

31:59

What has disruption taught us about global supply chains? Dr. Robert Handfield shares his vision on what agile and resilient supply chain models look like in the future. He is Professor of Operations and Supply Chain Management at North Carolina State University, as well as Founder and Executive Director of The Supply Chain Resource Cooperative. On this episode, Handfield joins host Alex Maiersperger to talk about the impact of the pandemic on global supply chains and provides insights into what has worked, what hasn’t, and what learnings we can apply in the future. Handfield speaks about the dependency on global supply chains for urgent medical supplies during the COVID-19 pandemic, such as masks and disinfectants, and inadequate national stock, due to a just-in-time inventory management system. Having strategic national stockpiles in place has become a major governmental and industry focus, as well as the effort to increase domestic sourcing of certain medical and pharmaceutical products. Handfield speaks about a shift towards regional supply chains and near shoring, a concept where a company transfers work to suppliers nearby in the region where possible, despite continuing to remain dependent on certain products from global supply chains. Finally, Handfield emphasizes that having the right technology, training and workforce in place, will be key to resilient and agile supply chain systems in the future. All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse S3E3: Why Forecast Agility Is King in the New World of Supply Chain Disruption 20:17

3 years ago20:17

20:17

For Felipe Sotelo, it’s all about priorities. That’s why Dad & Husband are the titles on his LinkedIn profile. It’s also why he now believes demand forecast agility is more important than accuracy in the post-pandemic world of supply chain disruptions. On this episode of The Health Pulse, positive thinker, business reinvention leader and writer Sotelo joins host Alex Maiersperger to share his insights as a supply chain leader for organizations including Johnson & Johnson, Teva Pharmaceuticals and PepsiCo. Forecast accuracy can never be perfect, and in a scenario full of disruptions, Sotelo argues that it’s more important to focus on agility and speed so that organizations can respond more effectively to disruptions. In his opinion, prioritization plays a big role, and the organizations that succeed are those that have both a strong leadership strategy and investment in technology and analytics to drive insights into keeping the strategy on track. The main focus now is regulating supply chains to ensure essential equipment is available. And, the new normal will prioritize both cost efficiency and reliability over cost efficiency alone. When asked about a light at the end of the tunnel for pandemic-related disruption, Sotelo predicts we won’t see it before 2024. But, that doesn’t keep him from being optimistic about the role of supply chain leaders in shaping a better, more sustainable future. All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse S3E2: Meet your digital health twin of the future 27:40

3 years ago27:40

27:40

Is it too much to expect health care to deliver delightful experiences? Dr. Koen Kas doesn’t think so, and his vision includes digital twins, personal data stores and preventive medicine. He is a health care visionary, digital health and biomarker expert, health-tech entrepreneur, Professor of Molecular Oncology and Digital Health at the University of Ghent, international keynote speaker and author of Sick No More and Your Guide to Delight. Host Alex Maiersperger and Kas talk about the concept of delight thinking, an approach that requires stakeholders to think outside the box – creating new health care delivery models, never imagined. Kas explains the fundamental difference between design thinking and delight thinking. Delight thinking has the patient at its core, rewarding health care systems for keeping patients healthy. Kas also speaks about the role of a digital twin for the future of health care and how far we are in the development. The twin is a full representation of the holistic health of a human, combining all health data from different sources into an avatar. Testing preventive or clinical measures on the avatar will enable a visualization of health outcomes, before implementing them on the human. Health care by default is another health care concept Kas introduces during the episode, including seamless health care via sensors in homes and automatic alerts to medical professionals. Finally, he emphasizes the key to prevention and personalized medicine is data integration and encourages health care systems to reward providers and citizens for preventing, predicting and reversing diseases. All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse S3E1: The (Not So) Secret to Making Cancer Care More Equitable and Effective 29:58

3 years ago29:58

29:58

Dr. Sean Khozin is on a mission to break down silos and improve access to quality cancer care for all. Khozin is a board-certified oncologist, physician scientist, data scientist and the CEO of ASCO’s CancerLinQ, a nonprofit health technology company focused on improving health outcomes for all patients with cancer. On this episode of The Health Pulse, Khozin joins host Alex Maiersperger to discuss how his organization is democratizing access to the best cancer care by bringing real-world evidence based tools to the point of care. As Khozin explains, only about 5% of cancer patients can access clinical trials. This means in oncology, clinical trial data often lacks external validity because it represents highly selective patient populations. CancerLinQ helps close the gap using real-world data to develop algorithmic support tools to inform personalized, multi-modal patient care in near-real time. Khozin also discusses precision medicine and reflects on how far we’ve come and opportunities to improve, particularly in the area of health care delivery. He also shares his perspective on regulatory science as translational science. From deriving insight from complex data to tackling treatment artifacts we need to unlearn, Khozin shares his vision for improving precision and why data convergence at the point of care leaves him optimistic about a major inflection point for cancer treatment in the next 10 years. Transcript available here . All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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Electrifying AI S3E1: Electricity Industry in Australia - A Global Perspective 26:20

3 years ago26:20

26:20

Our mission at ElectrifingAI is to bring you up-to-date insights on the latest developments taking shape in the electricity sector. Along the way, we’ll help demystify the connection between the greatest machine ever built — the electric grid — and the greatest enabler of our time — data analytics. To help us do that, we’ll have a series of guests who hold a variety of different roles within the industry. And for this episode, it’s a privilege to begin our third season … and our broader view of the electricity industry landscape … with someone who’s had a hand in crafting what that landscape looks like in his home country. Brett Redman is the CEO of Transgrid in Australia. Transgrid operates and manages the high voltage electricity transmission network in New South Wales and the Australian Capital Territory … connecting generators, distributors and major end users. And Brett is a seasoned executive who has … among other roles … previously served as the CEO of AGL and the chair of the Australian Energy Council. Just a decade ago, one could argue that the electricity industry was primarily a physical business, centralized in its existence, and with a very narrow view of customers and innovation. That world has changed drastically as innovation has shifted from the tangible to intangible. Hear from Brett his thoughts on how the industry is evolving and where we are headed into the future. About one in four Australian homes have rooftop solar panels, a larger share than in any other major economy, and the rate of installations far outpaces the global average. The country is well ahead of Germany, Japan and California, which are widely considered leaders in clean energy. But that great progress undoubtedly brings new complexities for grid operators and others who are tasked with ensuring uninterrupted service. We will hear from Brett his perspectives on such challenges and initiatives that are top on mind for him. Have questions or would like to share your thoughts? Jump into the discussion and reach out to Sal at https://www.sas.com/en/experts/sal-gill.html .... Or email us at: ElectrifyingAIpodcast@sas.com Learn more at http://www.sas.com/utilities . All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse S2E6: Improving Maternal Health through AI and Biomedical Science 21:55

4 years ago21:55

21:55

In this episode, Greg speaks with Professor Patricia Maguire, Director of University College Dublin’s Institute for Discovery. The Institute’s mission is to drive interdisciplinary research at UCD. Maguire is a biomedical scientist. Her research focuses on platelets, an interest that began 25 years ago when her father suffered his first heart attack and she recognized the need for better diagnostics in the clinic. Maguire explains that platelets circulate in our blood, picking up information along the way, which makes them a ready source of biomarkers. In one project, Maguire’s team works closely with three large maternity hospitals in Dublin, Ireland, on a study that has found new diagnostic markers for preeclampsia. Preeclampsia is a huge problem worldwide, affecting one in ten pregnancies, and killing 50,000 women and 500,000 babies and causing 5 million premature births each year, according to Maguire. Her team’s goal on the project is to bring diagnostic data from blood platelets together with all other available data on a mother during pregnancy and apply Artificial Intelligence (AI) and machine learning (ML) to extract insights that can be delivered to a clinician to inform critical care decisions, such as when a baby should be born. The analysis of multimodal data that can then be delivered to the computer screen of a clinician is an experience Maguire describes as augmented intelligence to support clinical decision making. Maguire says the ultimate dream of the team on this project is to partner with government and industry to bring the preeclampsia algorithm and diagnostic product to every woman who needs it around the world, saving lives. She also shares her thoughts on the importance of democratizing AI and analytics to improve knowledge sharing and collaboration from academia into the real world. A transcript of this episode can be found here . All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse S2E5: Creating a Healthier World with Ethical AI 27:55

4 years ago27:55

27:55

On this episode, Greg catches up colleague Reggie Townsend, director of the Data Ethics Practice at SAS. Recognizing the increasing market need around data ethics, SAS formed the practice to establish principles and processes for governing Artificial Intelligence (AI). Townsend defines AI as an algorithm or set of instructions given to a computer for decision making. He explains that the market definition of AI is now the entire analytics life cycle from the initial ingestion of data through to analytic modeling, data visualization and the decisions that are ultimately made. While examples of unethical AI, such as discriminatory hiring and lending practices, necessarily get a lot of attention, there are many more examples where AI is used to our benefit. Data science is deployed to optimize many aspects of daily life from our banking experience to flight routes to recommendation engines. SAS’ Data Ethics Practice applies a human-centric approach to upholding principles such as transparency, accountability and inclusivity in data science. Townsend challenges his team to start by considering the impact of technology on the most vulnerable populations. Understanding bias plays an imperative role. For example, Black neighborhoods in the US, like the one where Townsend grew up in Chicago, are more likely to be food deserts. The people in those communities lack access to healthy food and have poorer health outcomes as a result. When evaluating health data, it is critical to understand the facts and historical context behind the data in order to deliver effective decisions and solutions that are free of bias. Looking forward, Townsend is hopeful that the ethical development and deployment of AI-related technology can lead to brighter futures for all people. A transcript of this episode can be found here . All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse S2E4: Healthier Living Through Epigenetics Analysis 21:30

4 years ago21:30

21:30

On this episode, Greg is joined by Dr. Melissa Strong, founder and lead data scientist for IndiOmics. Her background is in molecular biology and epigenetics—or how our environment can affect our gene expression. The idea behind IndiOmics started when Dr. Strong was pregnant with her son and interested in better understanding chemical exposure in utero. The organization’s mission is to educate the public about common chemicals that have the ability to affect us on a cellular level and what we can do to avoid or prevent exposure. Much of its work focuses on endocrine-disrupting chemicals (EDCs). Participants receive a kit, provide a sample from home and ship the kit to the IndiOmics laboratory. When the results are ready, they can login for a personalized look at what they’ve been exposed to, how it’s affecting them on a molecular level and steps they can take to avoid or prevent additional exposure. For example, they may be able to cut down on EDC exposure by not heating or microwaving plastics. Dr. Strong explains that our gene expression is not set in stone, and our environment and behaviors play a significant role in determining our health. Particularly with EDCs, science has demonstrated the toxicity of even very low levels of chemical exposure. To learn more about what you can do to reduce your exposure to harmful chemicals, even if you don’t know your levels, Dr. Strong recommends visiting the Environmental Working Group’s website, www.ewg.org, and referencing the IndiOmics Healthy Living Pocket Guide at www.indiomics.org/pocket-guide . Looking to the future, Dr. Strong is encouraged by younger generations’ awareness around this issue and believes that consumer demand will drive action on the part of manufacturers and regulators alike to further reduce the use of harmful chemicals in consumer products. She also believes that blood tests on endocrine exposures will eventually become a part of routine medical care, empowering more people to understand their exposure levels and take steps to improve their health. All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse S2E3: Eradicating Disparities in Cancer Care with Social Determinants of Health Data 26:10

4 years ago26:10

26:10

On this episode, Greg Horne talks with Dr. Robert Winn, Director at VCU Massey Cancer Center. Dr. Winn is the second ever African American to be director of a cancer center in the United States. Growing up as the child of a 15-year-old mother, he didn’t dream of becoming a doctor, but two priests in his life saw his potential and helped him to get on a path that eventually led to medical school. In his role at Massey Cancer Center and his life, Dr. Winn focuses on two goals – eradicating cancer and eradicating disparities in access to quality health care wherever they exist. People who have access to quality treatment receive it. It’s that simple. And, trust and affordability play a critical role. As Dr. Winn explains, in order to earn people’s trust in science, the scientific and medical community must be trustworthy. That’s why Massey Cancer Center is working on a trustworthiness scale to measure how they are doing with their patients. Dr. Winn also shares his perspective on the role of health data convergence in improving health outcomes and the importance of using data from the community to improve scientific questions and address social determinants of health. When it comes to disparities in health care, we already know that a patient’s zip code has a significant impact on their health outcomes. Taken a step further, we can look at the implications of racism historically and identify how it is impacting health outcomes for African Americans today. Another foundational value for Dr. Winn is respect for humanity. He describes his awe and humility at both the power and limitations of science in treating cancer. He recognizes that there are some cancers and diseases that even today’s best medicine cannot fix. This is when it is imperative for cancer centers to ensure patients have the best possible palliative care to support their transition from this life. Finally, Dr. Winn leaves us with his thoughts on the cancer center of the future and the importance of data to better understand population health and communities. All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse S2E2: The Next Evolution of Decentralized Clinical Trials 25:01

4 years ago25:01

25:01

On this episode, Greg Horne interviews Craig Lipset, advisor, advocate and educator in the area of decentralized clinical trials and the former head of clinical innovation at Pfizer. During his time at Pfizer, Craig helped design and lead the first fully remote, decentralized trial. Surprisingly, that was more than a decade ago. In fact, Craig explains that the methods, investment and even the regulatory readiness around decentralized trials existed in the industry long before the pandemic. The lock-down disruption caused by COVID-19 in early 2020 delivered a key missing piece – meaningful adoption as the industry worked quickly to mitigate delays to ongoing research and spin up new trials to address the virus. Craig and Greg further discuss the potential for decentralized trials to make participation in clinical research more convenient and accessible to diverse and representative patient populations. Unique support is required to achieve this objective. Decentralized trial participants need specialized technical and emotional support to ensure they have a positive experience and are able to stay compliant with study protocols. In developing nations, decentralized methods can help researchers expand their work into areas where infrastructure may be lacking, but it’s critical to be mindful of the digital divide and ensure that the appropriate support is provided. Craig leaves us with his perspective on the role of decentralized trials in helping health care deliver clinical research as a care option. For example, the technology offers new ways to engage with non-investigator physicians to improve engagement with community health care and democratize access to clinical research. A transcript of this episode can be found here . All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse S2E1: Improving Health Equity and Health Outcomes with Analytics 21:31

4 years ago21:31

21:31

On this episode host Greg Horne interviews David Rhew, M.D., Global Chief Medical Officer & VP of Healthcare for Microsoft, on the role of technology in health care. Dr. Rhew, who has a background in infectious disease management, observed early in his career that evidence-based practices often lead to better health outcomes, but they aren’t adhered to consistently. From there he set out on a digital transformation journey that quickly brought him into health tech and eventually Microsoft. Dr. Rhew and Greg discuss the role of technology in delivering the right information at the right time to improve patient experience and outcomes. For example, in one cardiac rehab program where patients were offered the option to participation digitally, completion rate jumped from 40 to 80 percent and 30-day hospital readmissions dropped from 12 percent to less than 1 percent. Quite simply, making things easier for patients improves care and reduces costs. According to Dr. Rhew, the next horizon in health care will be around making data more interoperable so that the industry can bring it into a common platform and analyze it to drive actionable insights that improve care. And, Dr. Rhew leaves us with his parting thoughts on technology’s capacity to improve health equity and access. A transcript of this episode can be found here . All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse: Stacking the impact of clinical research to address unmet needs in health care. 23:15

4 years ago23:15

23:15

Jennifer Byrne, CEO of contract research organization Javara Research, has a lifelong passion for serving patient populations through clinical research. On this episode, Jennifer shares with Greg the concept of learning health systems that improve health care through research. Javara brings a lot of the traditional advantages that a CRO brings to pharma to health care systems through an integrated research organization approach. The organization's strategic vision and partnerships are centered around bringing clinical research opportunities to health care systems to meet unmet patient needs while simultaneously partnering with pharma to address the data and scientific needs to clinical trials. Jennifer explains how analytics and AI are used to deep dive into electronic health records and other health data sources to identify potential clinical trial participants and connect the right patient with the right trial and the right time. Greg asked Jennifer about the role of bias in clinical research, and she shares her experience around bias that patients and physicians aren’t as interested in participating in clinical research as they actually are. Technology can assist in physician and patient outreach and engagement, so that patients can come to clinical research with their trusted physician and keep their clinical trial participation in sync with their overall health care journey. They also discuss opportunities to use technology to deliver optimal and more patient-centric clinical trial participation. All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse: Modern Consumers Want to Know: How The Pharmaceutical Industry is Influencing Supply Chain Traceability 19:28

4 years ago19:28

19:28

Grainne Lynch, Senior Manager and Traceability Lead for Accenture, helps pharmaceutical companies be compliant with supply chain legislation around preventing counterfeit medicines from entering the supply chain. Her expertise is around helping pharmaceutical manufacturers implement common capabilities and coding to allow tracking and tracing of products at the unit level. On this episode, Grainne explains to Greg that the pharmaceutical industry is on the forefront of a consumer-led trend demanding the ability to track and trace products end-to-end throughout the supply chain. Now more than ever, consumers want to know a product’s entire history—where it came from, how materials were sourced, where and when it was manufactured, and the process by which it was approved. And, consumers expect companies to be responsible for making good decisions throughout the supply chain. This trend toward greater tracking and tracing is being seen in many industries, and as Grainne explains, life sciences is a natural leader because the industry already has GxP requirements in place. Data and analytics of course play a critical role. For example, most pharmaceutical products require refrigeration, and devices are used to monitor and measure refrigeration throughout the supply chain to ensure the proper temperature level is maintained. Grianne leaves us with her thoughts on the importance of pharmaceutical traceability to the future growth of the industry as a whole. All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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The Health Pulse: Follow the Money to Predict the Future of Health Care 23:48

4 years ago23:48

23:48

Jessica DaMassa is the Executive Producer and Host of video series, What’s the Future, Health?, where she interviews key stakeholders in health tech to uncover unique perspectives on where the industry is headed. On this episode of The Health Pulse, Jessica briefly switches from her usual role as interviewer to share her observations on the trends to watch right now in health care. She shares with Greg several clues on the future based on the unprecedented funding pouring into the health tech space since the early months of the pandemic. Start ups focused on improving analysis of data from electronic health records (EHRs), particularly those focused on gleaning predictive value from EHR data, are hot. Jessica also identified trends around funding for later-stage start ups, which indicates these companies are gaining traction, and an expansion in private equity money in the health tech space. So, where is all this new funding going? Jessica identified three key focus areas – mental health; technology that helps navigate patients into and through the health care system (also know as digital front doors); and AI implementation specifically in the areas of clinical trials and automation of health care administration. Greg and Jessica also discuss key considerations around identifying and controlling for bias in AI. Looking ahead to delivery of care, Jessica sees the home as a place of care will be a key pandemic trend that is here to stay. Her advice for start ups? Make sure you understand the payment model! All presentations represent the opinions of the presenter and do not represent the position or the opinion of SAS.…

The Health Pulse

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