The Making of KOLs: Understanding Germ Layer Origins in Cancer Therapy Response

The Making of KOLs: The New Chemist Podcast’s Global Journey in Science, Pharma, and Education

This episode discusses findings from a recent systematic review preprint, examining how the embryonic germ layer origin of various cancers may relate to differences in therapy response. Drawing on evidence from clinical trials and mechanistic studies, we explore patterns observed among mesoderm-, endoderm-, and ectoderm-derived tumors.

The conversation highlights how integrating developmental biology concepts into oncology may help inform treatment decisions and research design. This episode is intended for students, researchers, and clinicians interested in cancer biology, translational research, and personalized medicine.

Please note: The views of this podcast represent those of my guest and I, and do not constitute medical advice, recommendations or consultations. Please see a state certified and board certified professional for medical, advice and recommendations. We disclaim any loss in any way.

Link to Preprint: Embryonic Germ Layer Origin as a Potential Determinant of Cancer Therapy Response: A Systematic Review and Meta-Analysis of Contemporary Evidence | medRxiv

Note: Some of this episode's production involved the use of AI.