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Dr. David Blake - #25 - June 14, 2025
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Exploring Deep Brain Stimulation & Cognitive Function with Dr. David Blake | Neurostimulation Podcast
Join Michael Passmore, clinical associate professor in Psychiatry at the University of British Columbia, as he hosts Dr. David Blake, professor of neuroscience and regenerative medicine at Augusta University. In this episode, they delve into Dr. Blake's groundbreaking research on deep brain stimulation (DBS) and its effects on aging, cognitive function, and neuroplasticity. They discuss the latest findings presented at the 2025 Brain Stimulation Conference in Kobe, Japan, exploring the impact of DBS on neurotrophic markers in cerebrospinal fluid. This fascinating conversation unravels the potential of DBS in treating age-related cognitive decline, Alzheimer's disease, and broader applications such as Parkinson's disease and other neurocognitive disorders. Tune in to discover how Dr. Blake's interdisciplinary approach could revolutionize neurotherapeutics.
Blake Lab: https://www.augusta.edu/mcg/dnrm/faculty/blakelab.php
Cortical acetylcholine response to deep brain stimulation of the basal forebrain - Brain Stimulation Jan/Feb 2025 (Open access full text)
https://www.brainstimjrnl.com/article/S1935-861X(24)00979-3/fulltext
Intermittent stimulation of the basal forebrain improves working memoryin aged nonhuman primates Jan/Feb 2025 (Abstract)
https://www.brainstimjrnl.com/article/S1935-861X(24)00735-6/fulltext
Synchron: https://synchron.com
ECoG (Electrocorticography): https://en.wikipedia.org/wiki/Electrocorticography#:~:text=Electrocorticography%20(ECoG)%2C%20a%20type,activity%20from%20the%20cerebral%20cortex.
00:00 Introduction to the Neurostimulation Podcast
01:11 Sponsor and Guest Introduction
01:43 Deep Brain Stimulation Research Overview
04:04 Discussion with Dr. David Blake
06:27 Dr. Blake's Research and Findings
22:10 Future Directions and Applications
40:14 Brain-Computer Interfaces and Neuromodulation
45:10 Advice for Aspiring Neuroscientists
48:54 Conclusion and Farewell
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