Episode 14 Season 7: Chilly Dips, Flatfaced Pets, and Extending Dog Lifespan with Celine Halioua

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We explore the cutting-edge science of extending dog lifespan through innovative drug development with Loyal founder and CEO Celine Halioua, who shares the company's groundbreaking approach to canine longevity and health.
In Science News:
• Cold water immersion after exercise shows no benefits for women despite its popularity among fitness influencers

In Pet Science:

• Brachycephalic dog and cat breeds now resemble each other more than their wild ancestors due to selective breeding

Our Guest Speaks about:

• Loyal's first drug mimics the longevity benefits of caloric restriction without reducing appetite
• Large dog breeds age faster due to persistently high growth hormone levels that weren't naturally selected for
• Loyal is conducting the largest animal health study ever with 1,300 dogs to test longevity interventions
• The company hopes to bring their first longevity drug to market within a year
• The goal is to add at least one healthier year to dogs' lives while improving quality of life during aging
• Aging dogs develop many of the same diseases as aging humans, making them excellent models for longevity research
Loyal: https://loyal.com/
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Chapters

1. Introduction and Episode Overview (00:00:00)

2. Science News: Cold Water Dipping Benefits (00:01:54)

3. Pet Science: Brachycephalic Breeds (00:11:09)

4. Interview with Celine Halliwa (00:19:26)

5. Loyal's First Longevity Drug (00:27:13)

6. Big Dog Lifespan Drug Research (00:34:37)

7. Celine's Pet Story: Rescuing P Terry (00:48:35)

8. Episode Closing and Acknowledgments (00:55:06)