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Dark History of Clinical Trials Episode 3

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Manage episode 482289470 series 3508193
Content provided by Anna Fehr and Alexandria Clark, Anna Fehr, and Alexandria Clark. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Anna Fehr and Alexandria Clark, Anna Fehr, and Alexandria Clark or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

In this chilling episode of Dark History of Clinical Trials, we explore the devastating 2016 Phase 1 clinical trial in Rennes, France, that left one man dead and several others with lasting neurological damage. Designed to test a new painkiller, the study went catastrophically wrong after investigators escalated the dose without properly analyzing earlier data. We uncover what went wrong, the oversight failures, and how it shook public trust in drug development.

This tragedy serves as a sobering reminder of why data review, transparency, and ethical safeguards in early-phase trials are not just protocols—they are matters of life and death.

  continue reading

44 episodes

Artwork
iconShare
 
Manage episode 482289470 series 3508193
Content provided by Anna Fehr and Alexandria Clark, Anna Fehr, and Alexandria Clark. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Anna Fehr and Alexandria Clark, Anna Fehr, and Alexandria Clark or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

In this chilling episode of Dark History of Clinical Trials, we explore the devastating 2016 Phase 1 clinical trial in Rennes, France, that left one man dead and several others with lasting neurological damage. Designed to test a new painkiller, the study went catastrophically wrong after investigators escalated the dose without properly analyzing earlier data. We uncover what went wrong, the oversight failures, and how it shook public trust in drug development.

This tragedy serves as a sobering reminder of why data review, transparency, and ethical safeguards in early-phase trials are not just protocols—they are matters of life and death.

  continue reading

44 episodes

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