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🍬 Endothelium Under Attack: The Sweetener-Inflammation Link

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Manage episode 491928325 series 2740117
Content provided by MasterMedFacts LLC and RR Baliga MD. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by MasterMedFacts LLC and RR Baliga MD or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

🚨 New Findings on Aspartame & Heart Health! 🍬🫀

A groundbreaking study in Cell Metabolism reveals how aspartame, a common artificial sweetener, may worsen atherosclerosis via an insulin-triggered inflammatory pathway involving the CX3CL1-CX3CR1 axis.

🧪 Key insights from mice and monkeys:

– Aspartame spikes insulin via vagus nerve stimulation

– Elevated insulin boosts CX3CL1 expression in endothelial cells

– CX3CL1 recruits inflammatory monocytes ➡️ plaque growth & instability

🧬 Blocking CX3CR1 in monocytes stopped plaque progression entirely.

⚠️ Implications for diabetics, sweetener users, and those at risk of cardiovascular disease are profound.

#Atherosclerosis #Aspartame #Cardiology #PrecisionMedicine #Inflammation #Insulin #CX3CL1 #MedicalResearch #Podcast #CardioMetabolism

  continue reading

548 episodes

Artwork
iconShare
 
Manage episode 491928325 series 2740117
Content provided by MasterMedFacts LLC and RR Baliga MD. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by MasterMedFacts LLC and RR Baliga MD or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

🚨 New Findings on Aspartame & Heart Health! 🍬🫀

A groundbreaking study in Cell Metabolism reveals how aspartame, a common artificial sweetener, may worsen atherosclerosis via an insulin-triggered inflammatory pathway involving the CX3CL1-CX3CR1 axis.

🧪 Key insights from mice and monkeys:

– Aspartame spikes insulin via vagus nerve stimulation

– Elevated insulin boosts CX3CL1 expression in endothelial cells

– CX3CL1 recruits inflammatory monocytes ➡️ plaque growth & instability

🧬 Blocking CX3CR1 in monocytes stopped plaque progression entirely.

⚠️ Implications for diabetics, sweetener users, and those at risk of cardiovascular disease are profound.

#Atherosclerosis #Aspartame #Cardiology #PrecisionMedicine #Inflammation #Insulin #CX3CL1 #MedicalResearch #Podcast #CardioMetabolism

  continue reading

548 episodes

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