Stephen Wolfram is the creator of Mathematica, Wolfram|Alpha and the Wolfram Language; the author of A New Kind of Science; and the founder and CEO of Wolfram Research. Over the course of nearly four decades, he has been a pioneer in the development and application of computational thinking—and has been responsible for many discoveries, inventions and innovations in science, technology and business. On his podcast, Stephen discusses topics ranging from the history of science to the future of ...
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A regular series exploring issues related to sustainable development and economic justice in low and middle income countries. Produced by the Economic Growth Center at Yale University.
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A podcast about diabetes and genes hosted by Andrew Hattersley and Maggie Shepherd.
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Host Gatley Stone interviews some of NC State’s most distinguished professors to learn about their research and how they made it to where they are today. This series is made possible thanks to NC State's student radio station, WKNC 88.1 FM HD-1/HD-2.
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Development Dialogues: Who will pay for the global energy transition?
39:28
39:28
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39:28In this episode of Development Dialogues, host Catherine Chaney is joined by Max Bearak, Anant Sudarshan and Jessica Seddon to examine one of the most complex challenges in global development: how can the clean energy transition move forward both quickly and equitably, particularly for low- and middle-income countries (LMICs) still grappling with p…
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Series 3 Episode 14: Farah O'Regan and Matt Johnson. Down syndrome and very young onset diabetes
33:26
33:26
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33:26Farah O'Regan talks about how her son who had Down syndrome and a severe congenital heart condition needing surgery diagnosed in pregnancy and then developed Type 1 diabetes on day 2 of life. In early childhood he was diagnosed with 2 more autoimmune conditions, coeliac disease and hypothyroidism. Researcher Matt Johnson explains his research which…
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Development Dialogues: Are vocational training programs effective?
37:40
37:40
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37:40Vocational training programs are designed to boost employment in low- and middle-income countries — but often they fall short. In the fourth in our series of Development Dialogues, we examine the real impact of vocational training programs in low- and middle-income countries. Our guests take on pressing questions around evidence, expectations, mark…
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Series 3 Episode 13. Abby Gardener and Tim Barrett. Wolfram syndrome / WFS1 Spectrum disorder
34:53
34:53
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34:53Abby Gardener describes how she was diagnosed with Wolfram syndrome after developing both insulin-treated diabetes and diabetes insipidus (when the urine cannot concentrate) and how this has impacted her life. Professor Tim Barrett talks about how, throughout his career, he has been researching and providing care for patients with Wolfram syndrome.…
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Future of Science and Technology Q&A (March 14, 2025)
1:24:08
1:24:08
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1:24:08Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: What, exactly, is an "AI agent"? "Agentic"? It seems like nobody knows what those words actually mean today. - Can you tell us abo…
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Business, Innovation and Managing Life (March 12, 2025)
1:26:45
1:26:45
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1:26:45Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qa Questions include: Is academia the only real career path if one just wants to learn and do research? - What are the risks for using AI/LL…
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Series 3 Episode 12. Cassi Connelly. Familial Partial Lipodystrophy
36:01
36:01
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36:01Cassi Connelly talks about her experience of having familial partial lipodystrophy characterised by a loss of fat and muscular appearance of her arms and legs. She had multiple medical problems including diabetes for decades before the diagnosis of familial partial lipodystrophy was finally confirmed by a genetic test. Her treatment is now better t…
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Science & Technology Q&A for Kids (and others) [March 7, 2025]
1:21:53
1:21:53
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1:21:53Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: Can you talk about lambda calculus? - Any thoughts on numerology? - My current favorite approximation to a constant (e, in this case) …
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History of Science & Technology Q&A (March 5, 2025)
1:24:39
1:24:39
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1:24:39Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: What is the history of game theory? What are some successful and less successful applications of this theory? Can you speak about…
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Business, Innovation and Managing Life (February 26, 2025)
58:38
58:38
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58:38Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qa Questions include: Physicists that "could code" used to be the hot commodity; is it helpful now? Seems like CS/ML people are more in dema…
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Series 3 Episode 11. Rebecca Goodman. Living well with Bardet-Biedl syndrome.
29:14
29:14
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29:14Rebecca Goodman talks to Andrew and Maggie about what it is like to grow up with Bardet-Biedl syndrome. Features of Bardet-Biedl syndrome include extra fingers and toes, progressive blindness, kidney problems, obesity due to an uncontrolled appetite, insulin resistance and diabetes. Despite this long list of medical issues Rebecca lives independent…
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History of Science & Technology Q&A (February 19, 2025)
1:24:47
1:24:47
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1:24:47Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: - Can you talk about the history of pi? - "Pi day of the century." - Is pi still being researched today? Or is it a solidified co…
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Development Dialogues: The future of evidence-based policymaking and international development
42:19
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42:19In this episode of Development Dialogues, Rory Stewart, Stefan Dercon, and Trudi Makhaya join host Catherine Cheney to discuss the challenges of evidence-based policy in an era where populism and narratives often outweigh facts. The conversation centers around how to ensure facts and evidence still matter in policymaking and international developme…
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Future of Science and Technology Q&A (February 14, 2025)
1:08:07
1:08:07
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1:08:07Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: In the spirit of Valentine's Day, what is the future of bionic hearts? Would this be a way to make humans more efficient? - How wo…
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Business, Innovation and Managing Life (February 12, 2025)
1:16:39
1:16:39
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1:16:39Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qa Questions include: What are the qualifications to be considered an "expert" in a specific field of science? - What do you think was the h…
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Special episode 5. John Dennis. Research breakthrough in Type 2 diabetes treatment.
24:01
24:01
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24:01We talk to John Dennis, a data science researcher working in the University of Exeter. He used data from 1 million people with Type 2 diabetes to discover how the clinical characteristics of a patient alter the glucose lowering with different treatments. John’s 5 drug model, published in the Lancet in late February 2025, uses simple clinical inform…
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History of Science & Technology Q&A (February 5, 2025)
1:30:28
1:30:28
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1:30:28Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: When was complexity science invented? Was there a further back history than digital? - They always forget Aristarchus. - What rol…
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Future of Science and Technology Q&A (January 31, 2025)
1:17:16
1:17:16
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1:17:16Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: Do you imagine humanity exploring "inner space" (i.e. virtual worlds ) more than "outer space"? - Could the spin of electrons lead…
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Business, Innovation and Managing Life (January 29, 2025)
1:24:03
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1:24:03Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: How do we know how far stars, galaxies, etc. are in space? - Can you tell about the science of gem cutting, brilliance, internal refra…
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Science & Technology Q&A for Kids (and others) [January 24, 2025]
1:29:04
1:29:04
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1:29:04Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: How do we know how far stars, galaxies, etc. are in space? - Can you tell about the science of gem cutting, brilliance, internal refra…
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Series 3 Episode 10. Julie Reynolds and Kash Patel. Maternally inherited diabetes and deafness
33:05
33:05
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33:05Julie Reynolds describes how she gradually lost her hearing in her 30’s and developed diabetes in her 40’s these 2 conditions also developed in in her mother, her children and other maternal relative. This led to a diagnosis of maternally inherited diabetes and deafness that results from a change in the mitochondrial DNA. Kash Patel explains the sc…
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History of Science & Technology Q&A (January 22, 2025)
1:23:39
1:23:39
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1:23:39Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: How would Stephen Wolfram think about "the new world"? Would you have been surprised by the "discovery" of North and South Americ…
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Future of Science and Technology Q&A (January 17, 2025)
1:18:27
1:18:27
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1:18:27Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: How would you think about approaching science in the future? Should we accept AI's role in future science or still pursue science …
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Business, Innovation and Managing Life (January 15, 2025)
1:25:11
1:25:11
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1:25:11Stephen Wolfram answers questions from his viewers about business, innovation, and managing life as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-business-qa Questions include: How would you think about approaching a business from a science and research background vs. an entrepreneur? - Do you …
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Series 3 Episode 9. Ru Kovvuri and Rhian Clissold Cognitive and medical impacts of the HNF1B deletion syndrome
37:44
37:44
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37:44Ru Kovvuri explains about her battle to get a diagnosis and support for her daughter who had multiple medical problems and learning difficulties as a result of a deletion of the HNF1B gene. Rhian Clissold discusses her research to improve the diagnosis of the HNF1B syndrome and recognise the associated learning difficulties seen with loss (deletion…
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Science & Technology Q&A for Kids (and others) [January 10, 2025]
1:20:43
1:20:43
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1:20:43Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: My question is, When we transfer an electric charge to a conducting sphere, does this charge cause some metal atoms to become ions? If t…
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History of Science & Technology Q&A (January 8, 2025)
51:34
51:34
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51:34Stephen Wolfram answers questions from his viewers about the history of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: Any progress on your understanding of Buddhist philosophy from digging into East Asian history? - How do we address the interesti…
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Future of Science and Technology Q&A (January 3, 2025)
1:20:46
1:20:46
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1:20:46Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: What is your view on LLMs with regard to computational irreducibility—i.e. will they hit a computational irreducibility wall anyti…
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Series 3 episode 8. HNF1Beta syndrome: kidney disease, diabetes, liver dysfunction and much more
48:13
48:13
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48:13Grant King talks about his diagnostic journey where his low birth weight, childhood kidney disease, diabetes, liver dysfunction and infertility were at 32 years finally recognised as all being due to a change in the HNF1Beta gene. Dr Coralie Bingham explains how her research during her PhD in Exeter led to HNF1Beta being established as the commones…
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Science & Technology Q&A for Kids (and others) [December 27, 2024]
1:26:18
1:26:18
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1:26:18Stephen Wolfram answers general questions from his viewers about science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: What is computation? How does matter go from randomly moving particles to something that starts "computing"? - My son watched The Matrix…
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Future of Science and Technology Q&A (December 20, 2024)
1:07:22
1:07:22
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1:07:22Stephen Wolfram answers questions from his viewers about the future of science and technology as part of an unscripted livestream series, also available on YouTube here: https://wolfr.am/youtube-sw-qa Questions include: Do you foresee Notebook Assistant breaking out of the notebook in the future? It could be a great general voice assistant which …
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