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Bioenergetics and Brain Health 4: Brain Aging, Alzheimer’s and Parkinson’s Diseases, and Stroke

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Manage episode 452063626 series 3558288
Content provided by Mark Mattson. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Mark Mattson or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

In this final episode of the Bioenergetics and Brain Health series I talk about changes that occur in brain cells during normal aging, and in Alzheimer’s disease, Parkinson’s disease, and stroke with emphasis on alterations upstream and downstream of cellular energy metabolism. The episode concludes with examples of therapeutic interventions that target those age- and disease-related alterations.

LINKS:

Hallmarks of Brain Aging

https://pmc.ncbi.nlm.nih.gov/articles/PMC6039826/pdf/nihms979409.pdf

Brain Energy Rescue:

https://pmc.ncbi.nlm.nih.gov/articles/PMC7948516/pdf/nihms-1624328.pdf

The Hormesis Principle of Brain Health and Resilience

https://pmc.ncbi.nlm.nih.gov/articles/PMC5209274/pdf/nihms834422.pdf

  continue reading

165 episodes

Artwork
iconShare
 
Manage episode 452063626 series 3558288
Content provided by Mark Mattson. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Mark Mattson or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

In this final episode of the Bioenergetics and Brain Health series I talk about changes that occur in brain cells during normal aging, and in Alzheimer’s disease, Parkinson’s disease, and stroke with emphasis on alterations upstream and downstream of cellular energy metabolism. The episode concludes with examples of therapeutic interventions that target those age- and disease-related alterations.

LINKS:

Hallmarks of Brain Aging

https://pmc.ncbi.nlm.nih.gov/articles/PMC6039826/pdf/nihms979409.pdf

Brain Energy Rescue:

https://pmc.ncbi.nlm.nih.gov/articles/PMC7948516/pdf/nihms-1624328.pdf

The Hormesis Principle of Brain Health and Resilience

https://pmc.ncbi.nlm.nih.gov/articles/PMC5209274/pdf/nihms834422.pdf

  continue reading

165 episodes

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