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Fat Cell Recall: Why Losing Weight Isn’t the End of the Story

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Manage episode 454511417 series 6004
Content provided by Dee and Michael McCaffrey and Michael McCaffrey. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dee and Michael McCaffrey and Michael McCaffrey or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

Why do people regain weight more quickly than expected after successfully losing it? Research shows that once someone has been overweight or obese, the genes in their fat cells undergo changes, creating a "memory" of the overweight state. This makes it easier for the body to return to that state. Listen in this week as Dee discusses this fascinating research, and what it means for long term weight loss maintenance.

Reference:

Hinte, L. C., Castellano-Castillo, D., Ghosh, A., Melrose, K., Gasser, E., Noé, F., Massier, L., Dong, H., Sun, W., Hoffmann, A., Wolfrum, C., Rydén, M., Mejhert, N., Blüher, M., & Von Meyenn, F. (2024). Adipose tissue retains an epigenetic memory of obesity after weight loss. Nature, (2024). https://www.nature.com/articles/s41586-024-08165-7

  continue reading

581 episodes

Artwork
iconShare
 
Manage episode 454511417 series 6004
Content provided by Dee and Michael McCaffrey and Michael McCaffrey. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Dee and Michael McCaffrey and Michael McCaffrey or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

Why do people regain weight more quickly than expected after successfully losing it? Research shows that once someone has been overweight or obese, the genes in their fat cells undergo changes, creating a "memory" of the overweight state. This makes it easier for the body to return to that state. Listen in this week as Dee discusses this fascinating research, and what it means for long term weight loss maintenance.

Reference:

Hinte, L. C., Castellano-Castillo, D., Ghosh, A., Melrose, K., Gasser, E., Noé, F., Massier, L., Dong, H., Sun, W., Hoffmann, A., Wolfrum, C., Rydén, M., Mejhert, N., Blüher, M., & Von Meyenn, F. (2024). Adipose tissue retains an epigenetic memory of obesity after weight loss. Nature, (2024). https://www.nature.com/articles/s41586-024-08165-7

  continue reading

581 episodes

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