The Science of Myostatin inhibitors, GLP-1 meds and Muscle Mass

Docs Who Lift

• Dr. Grant Tinsley joins the discussion as the body composition expert.
• Myostatin is a key regulator of muscle growth.
• Wendy Whippete the most jacked muscled up dog
• The concern of GLP-1 receptor agonists and muscle mass loss.
• Overview of Courage trial looking at semaglutide and trevogrumab and lean mass loss
• Upcoming Believe trial coming out (bimagrumab and semaglutide)
• Exercise remains crucial for muscle health and function.
• MRI data from SURPASS MRI provides new insights into muscle volume changes.
• The combination of medications may have varying effects on muscle mass.
• Caution is advised regarding the long-term effects of new drugs.
• Clinical benefits of medications often outweigh concerns about muscle loss.
• Future research will explore the synergy between exercise and medication.

Other docs who lift podcasts with Dr. Grant:

Tirzepatide muscle loss

Lean mass loss and GLP-1 meds