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Unleashing Fibrotic Secrets: Coupling the Power of Laser Microdissection with Mass Spec

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Manage episode 446212475 series 3391756
Content provided by Bitesize Bio. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Bitesize Bio or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

Tissue heterogeneity is a significant challenge when analyzing proteins in tissue samples to identify disease states.

In this episode, explore how combining laser microdissection with mass spectrometry (LCM-MS) on fixed and stained tissues lets you explore the protein networks within pathological features to shed light on their molecular functions.

Using hallmark lesions of lung fibrosis in the honeycomb airways and fibroblastic foci as an example, you'll hear how this technology can detect over 4,900 proteins from tissue volumes as low as 0.005 mm3.

Watch the full presentation here: https://events.bitesizebio.com/unleashing-fibrotic-secrets/join

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

  continue reading

141 episodes

Artwork
iconShare
 
Manage episode 446212475 series 3391756
Content provided by Bitesize Bio. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Bitesize Bio or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.

Tissue heterogeneity is a significant challenge when analyzing proteins in tissue samples to identify disease states.

In this episode, explore how combining laser microdissection with mass spectrometry (LCM-MS) on fixed and stained tissues lets you explore the protein networks within pathological features to shed light on their molecular functions.

Using hallmark lesions of lung fibrosis in the honeycomb airways and fibroblastic foci as an example, you'll hear how this technology can detect over 4,900 proteins from tissue volumes as low as 0.005 mm3.

Watch the full presentation here: https://events.bitesizebio.com/unleashing-fibrotic-secrets/join

Browse all episodes of the Listen In Series here: https://listen-in.bitesizebio.com/

  continue reading

141 episodes

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