S9 E11 | Vital But Often Overlooked Factors In Recurrent Miscarriage and Pregnancy Loss

The Worst Girl Gang Ever

In this deeply insightful episode of The Worst Girl Gang Ever, we welcome back Dr. Sami, Fertility Consultant at Plan Your Baby, to unpack a vital but often overlooked factor in recurrent miscarriage and pregnancy loss: blood clotting disorders, also known as thrombophilias.

Dr. Sami explains:

• What inherited and acquired clotting disorders are

• How conditions like Factor V Leiden, Prothrombin mutations, and Antiphospholipid Syndrome (APS) dramatically increase the risk of miscarriage

• Why APS is one of the most treatable causes of miscarriage with aspirin and heparin therapy

• The shocking statistic: with proper treatment, miscarriage rates can drop from 80% to just 20%

• Why many women are told "everything is normal"—and why that may be far from the truth

• What you can and should ask for if you’ve had two or more miscarriages

• The difference in treatment approaches between NHS vs private fertility care

In this episode, we discuss:

• Recurrent miscarriage causes and treatments

• Blood clotting and pregnancy loss

• APS and miscarriage

• Factor V Leiden miscarriage risk

• Miscarriage and low-dose aspirin

• Heparin in pregnancy

• Fertility consultant insights

• Blood thinning medication in pregnancy

• Safe treatments for preventing miscarriage

• Plan Your Baby fertility support

Whether you’ve been through pregnancy loss or are supporting someone who has, this episode offers hope, science, and practical steps toward your next healthy pregnancy.

About The Worst Girl Gang Ever

The Worst Girl Gang Ever is a real, honest, and emotive podcast that covers the heartbreaking subject of miscarriage, infertility, and baby loss. Expect raw conversations about unspoken experiences, hosted by TWGGE founders Bex Gunn and Laura Buckingham. This show aims to break the silence and open dialogue around miscarriage and pregnancy loss. No more shame, no more taboo—let’s change the narrative for future generations.

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We are here to tell you that you are entitled to grieve, and that your grief is not disproportionate to your loss. We are here to oxapen up the dialogue around miscarriage, so we don’t perpetuate the shame, judgement and isolation so many of us feel following pregnancy loss. We are here to equip you with knowledge, tools and guidance to support and help you in whatever way you need.

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