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The most engaging conversation between health professionals happens in chance meetings in the hallways. During these moments so much is learned .*One Thing* brings together thought leaders in conversation and we share it with health enthusiasts , practitioners, and learners. Our conversations primarily focus on one significant thing in the arenas of gut health, brain health, immune system, metabolism, performance, and aging . This for clinicians and patients alike who are insightful and moti ...
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Brianna Approved

Dr. Brianna Diorio

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A lifestyle podcast dedicated to bringing you real science & clinical research about all things health, nutrition, botanicals and balance. Approaching complex subject matters with directness and humor. Hosted by Dr. Brianna Diorio—Integrative Medicine PhD, Clinical Nutritionist MS, Holistic Lifestyle Coach, FDN, Herbal Practitioner, NASM CPT.
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In this episode, Dr. Adam Rinde welcomes back microbiologist and PolyBio Research Foundation co-founder Dr. Amy Proal. Together, they unravel a framework for understanding chronic illnesses through the lens of persistent infections and their impact on mitochondria, immunity, and neurological health. Dr. Proal shares cutting-edge research linking pa…
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This week on The One Thing Podcast, host Dr. Adam Rinde welcomes back renowned rheumatologist Dr. Aly Cohen to dive deep into her groundbreaking new book, "Detoxify" (releasing May 2025!). Forget extreme deprivation and unsustainable measures. Dr. Cohen shares her balanced, practical, and science-backed approach to navigating the environmental toxi…
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In the 80th episode of the podcast we are diving into something I know many of us wrestle with: cognitive loops. In the episode, I discuss: What a cognitive loop actually is and why your brain gets hooked on them The role your ego plays in keeping you stuck in loops like the validation loop, justice loop, and control loop Why these loops feel addic…
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In this episode, Dr. Adam Rinde sits down with integrative medicine specialist Dr. Carla Kuon from University of California San Francisco (UCSF) to explore the latest insights into long COVID, chronic fatigue syndrome, and post-viral illnesses. Dr. Kuon shares powerful breakthroughs from her clinical work and research—especially around mitochondria…
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In this episode of The One Thing Podcast, Dr. Adam Rinde and Dr. Paul Anderson discuss a powerful concept shaping chronic illness care: the Cell Danger Response (CDR). If you or someone you know is dealing with persistent fatigue, inflammation, long COVID, or autoimmune challenges, this discussion offers deep insights into what may be happening at …
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In episode 79 of the podcast, we will explore the high achiever’s baseline effect and the neuroscience behind why high performers struggle to rest (and why burnout ensues). We'll break down the trap of tying self-worth to productivity, how to rewire the subconscious belief that rest is unproductive, and the shift from identifying as a "hard worker"…
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In this episode of The One Thing Podcast, host Adam Rinde interviews neurologist Dr. Sui Wong to discuss a revolutionary approach to migraine management. Migraines are often treated reactively, but what if we could build resilience against them from the ground up? Dr. Wong shares insights into how lifestyle interventions, brain resilience, and nerv…
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Parkinson's and gut health: The connection you need to understand! Uncover practical steps you can take today to support a healthier gut environment and improve overall well-being for both patient and caregiver In this episode of The One Thing Podcast, Dr. Adam Rinde dives deep into the fascinating world of the microbiome with Martha Carlin, a citi…
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In episode 78 we are getting into the science (and neuroscience) of change aka self-directed neuroplasticity! I discuss how change actually happens in the brain, why discipline is more important than motivation, how to create and stick to habits, and why systems and processes are more important than goals! Nerd Alert- Parts of the brain that deal w…
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Episode summary and time stamps I. Introduction (0:00-1:31) Host Intro: Introduces Gillian Ehrlich, DNP, ARNP,(Neuroveda Health), highlighting expertise in complex chronic illness, blending #Ayurveda, conventional nursing, #functionalmedicine, and #integrativemedicine. Mentions therapies: #ketamine, #plasmapheresis, #IVtherapies, and conditions tre…
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My favorite solo episode to date! In this episode I will introduce the concept of transformational vocabulary and dive into how the words you chose shape your emotions, behaviors, perceptions and ultimately quality of life. We will explore practical tools for elevating emotional vocabulary, working on cognitive reframing, and transforming life thro…
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It is the first episode of 2025, of course we are talking about mental health! In episode 76 I sit down with John Scafiddi Jr, founder & creative director At War World Wide & host on The Journey Podcast. We talk about being at war with yourself and how they can be a catalyst for personal growth, we discuss how to pour back into your own cup (and fi…
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Is Long COVID wreaking havoc on your nervous system? In episode 110 of The One Thing Podcast, Dr. Adam Rinde interviews Dr. Robert Groysman, an anesthesiologist (MD), and pioneer in treating dysautonomia (autonomic nervous system dysfunction) and post-viral illness. Discover groundbreaking therapies, including:* **Vagal Nerve Stimulation (VNS):** L…
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In episode 75 of the podcast, we are talking all things Positive Psychology, which is the scientific study of optimal human functioning. In this epsiode I disucss: Positive Psychology 101 (5 Core Pillars) Improving the Quality of Your Life Happiness Is A Skill Redefining Failure ___ Be sure to follow my Instagram @briannadiorio for all the Brianna …
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In this Episode I welcome on Sami Inkinen CEO of Virta Health to discuss Virta Health's approach to Type 2 Diabetes reversal' Virta Health utilizes a continuous remote care intervention (CCI) that incorporates individualized carbohydrate restriction, health coaching, and telemedicine to manage and reverse Type 2 Diabetes We cover topics such as: Im…
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In this episode of The One Thing Podcast, hosted by Dr. Adam Rinde, the focus is on integrative and naturopathic medicine, specifically addressing complex chronic illnesses and cancer care. Dr. Rinde introduces the guest, Dr. Paul Anderson, a leading voice in the field with over 30 years of clinical experience. The episode aims to explore the topic…
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In episode 74 I am talking all things menstrual cycle! I discuss: The 4 Phases Of Your Menstrual Cycle The Connection Between Your Skin Health & Period Hormones Impacting Your Mood Menstrual Cycle Hormones 101 ___ Be sure to follow my Instagram @briannadiorio for all the Brianna Approved educational content! You can visit my website www.briannadior…
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In episode 73 we are talking all things optimizing sleep, circadian rhythm & sleep cycles. In this episode, I discuss: -Circadian Rhythm 101 -The Importance of Slow Wave Sleep / Deep Sleep -Science Behind The Importance Of An Early Bedtime -Why All Blue Light Isn't Bad -Hormonal Peaks During Sleep __ Be sure to follow my Instagram @briannadiorio fo…
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The Toxins We Ignore: Insights from Dr. Pizzorno on Naturopathic Medicine, Detoxification, and Environmental Contaminants .In this episode of the One Thing Podcast, we have the honor of speaking with Dr. Joseph Pizzorno, a pioneering naturopathic physician, educator, researcher, and author. Dr. Pizzorno' s profound influence on the field of naturop…
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In this episode of the One Thing podcast, Dr. Peterdiscusses the profound impact of her father's experiences as a Holocaust survivor on her life and career as a trauma psychologist. The conversation delves into the effects of generational trauma, the physiological and psychological responses to significant traumatic events, and the steps taken to a…
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In episode 72 I sit down with Steven Kahn, Product Development Scientist at Onnit, a supplement company focusing on total human optimization and scientifically proven ingredients. We discuss:-Supplement Formulation Basics-Standardized Ingredients Vs Proprietary Blends-Avoiding Supplement Marketing -Melatonin Myths Watch our conversation on YouTube …
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In episode 105 of the One Thing Podcast, Dr. Adam Rindeinterviews Dr. Sandra Paulsen, a renowned psychologist and author, about her professional journey and expertise in psychotherapy, focusing on her work with autism and Eye Movement Desensitization and Reprocessing (EMDR). Dr. Paulsen discusses her own experiences with autism, her approach to tre…
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In today’s episode, we have the honor of hosting a truly remarkable guest, Dr. Amanda Lynn Hoffman. As the first Naturopathic physician with Marfan syndrome to specialize in this field, Dr. Amanda Lynn offers invaluable insights for both individuals living with Marfan's Syndrome and their caregivers. Her groundbreaking work in Naturopathic medicine…
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On episode 71 of the podcast, I sit down with Daryl Nault, a researcher at Examine.com, the largest database of nutrition and supplement research on the internet. In this episode, we discuss: Hierarchy of scientific evidence Research literacy How to reduce research biases Cherry-picking scientific data Daryl is a dedicated researcher, accomplished …
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Episode 103: Conscious Eldering with Ron Pevny These days, getting older seems to be more like a war rather than a rite of passage. "Take this pill or this potion to reverse aging and stay young," they say. But is that really how we should view aging? We question this and more in this episode, where I welcome Ron Pevny, the director of the Center f…
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In episode 70 I break down the actual science of vibes! I discuss co-regulation of the nervous system, limbic resonance, emotional residue and the heart-brain connection.I also get into why we rise to the occasion when we are surrounded by the right people (The Pygmalion Effect), how to increase heart coherence, and how to raise those vibes! You ca…
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Welcome episode to 102! featuring Geoff Lecovin, a naturopathic doctor, chiropractor, acupuncturist, and expert in breathwork. Dr. Lecovin provides an in-depth explanation of breathwork, its history, physiological effects, and benefits. He discusses how breathwork can induce altered states of consciousness and access the body's innate healing abili…
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Dr. John Douillard, DC, CAP is a globally recognized leader in the fields of natural health, Ayurveda, and sports medicine, and has been teaching Ayurvedic wisdom for 40 years. He is the creator of LifeSpa.com, where ancient Ayurvedic wisdom meets modern science. LifeSpa.com is one of the leading Ayurvedic health and wellness resources on the web w…
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In episode 68 I sit down with Gena Bradshaw, a holistic health and energy coach, two-time cancer survivor, and author of A Survivors Story, A Holistic Healing Journey Through Cancer. In this episode, we discuss: -Understanding your “energy bucket”-Chakra System Basics-Prioritizing Healing Modalities-Evolving Your Holistic Healing Journey Watch the …
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Pediatric Acute Onset Neuropsychiatric Disorder Associated with Streptococcus Infection and Pediatric Acute-onset Neuropsychiatric Syndrome is a troubling condition that involves sudden onset of OCD, anxiety, tics, sometimes aggression, sometimes ADHD, sometimes depression, sometimes dysgraphia.. that abruptly happens almost overnight. In some case…
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In this episode I discuss all things Berberine and why I love it as a plant compound! I discuss Berberine's MOA, benefits, GLP1 basiscs/ how that relates to Ozempic, cellular, and molecular targets for Berberine (such as AMPK + Sirtuins) how it works on dosage and contraindications. -Berberine Mechanism of Action -GLP-1 Overview-Molecular Targets f…
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Episode 100 of the One Thing Podcast with Dr. Adam Rinde did not disappointFirst, some goodies to mention. To order the Jona test we talk about this episode... go to https://jona.health and enter ONETHING100 to receive $100 off the testIn this episode I welcome on the CEO of Jona, Leo Grady, PhD and the Director of Business Development and GTM stra…
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In episode 66 I have a return guest and one of my favorite homies for life, Isaiah Frizzelle. In this episode, we talk about: -Embracing Being By Yourself -Communication Vs Comprehension -Friendship Breakups -Transparency vs Vulnerability You can watch the full YouTube video here and watch our first episode together (episode 32) here! Follow all th…
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The guest in this episode is Dr. Andrea McBeth, the CEO of Thaena , who talks about postbiotics and their role in addressing health imbalances. The podcast emphasizes the importance of consulting with a healthcare provider before making any changes to one's health routine. Dr. McBeth has dedicated this episode to Lesbians Who Tech https://lesbiansw…
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In my first segment of Trickle Down Therapy, I sit down with my favorite people (and Brianna Approved homies) to have some meaningful conversations, purposely ponder life, and hopefully have a few laughs and nuggets of wisdom along the way! I sit down with Doreen Korba, psychologist, business and life coach and we discuss:4 points -The self-awarene…
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Much emphasis is being placed on the gut microbiome to look for therapeutic derivatives that provide health and medicinal benefit. And in addition, we have another natural source of compounds from human breast milk that provides a wide range of therapeutic and medicinal properties. Everybody knows about colostrum; however, this range of health cons…
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Nutritional therapy plays a significant role in managing inflammatory bowel disease (IBD), but it is often overlooked in traditional medical care. Exclusive enteral nutrition is effective in inducing remission, while therapeutic diets like the IBD-Anti-Inflammatory Diet and the Specific Carbohydrate Diet have shown positive results. Monitoring nutr…
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In episode 64 we are talking about the neuroscience behind doing hard things. I also discuss why doing hard things is actually good for your brain, why you should embrace becoming an imperfectionist, and 5 tips for tricking your brain into doing things it doesn’t want to do! Nerd Alert: Neuroscience of Effort + Willpower (and parts of the brain ass…
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Claire Hall, a researcher at Mindset Health, joins us on episode 96 discusses menopause and the effectiveness of hypnotherapy in treating hot flashes. Summary of episode: Hypnotherapy is an effective non-drug alternative for managing hot flashes, as it has been shown to reduce their frequency and severity. It has shown in trials that hypnotherapy c…
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In episode 63 I sit down with Brendan, a Mental and Metabolic Health Scientist & Researcher, Functional Medicine Educator, Writer, and Speaker. Brendan is the owner and founder of the Metabolic Solutions Institute for Functional Health and Fitness Practitioners and the creator of the Functional Mental Health Practitioner Certificate Course & the cr…
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Welcome to Episode 95: Cardiovascular endothelium health with Dr. Kristine Burkepodcast is dedicated to Alzheimer’s Prevention and Reversal Project Foundation. If we reach 500 listens withinthe first 30 days, we will make a donation in honor of our guest Dr. Burke. Episode 95: Cardiovascular endothelium health with Dr. Kristine Burke In this episod…
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In episode 62 I sit down with Marni Salup, entrepreneur, triathlete, brand Builder, marketing and PR pro, and thought leader. Marni is also the founder of The Salup Group, founded in 2000, a brand development, partnership, and communications agency, founder of media brand On The Move Media, and creator & host of the Marni On The Move podcast. Marni…
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In episode 61 I sit down with Ronit Menashe and Vida Delrahim, the founders of ⁠WeNatal,⁠ a prenatal supplement company intentionally designed for women and men. WeNatal aims to change the narrative surrounding fertility and pregnancy, shifting the focus from "me" to "we." We discuss leveling up your conception game, understanding egg & sperm quali…
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In my 60th episode of the podcast, I am sharing some of my favorite tips that will help you 10x your productivity this year! I explain the differences between habits and routines and give you 4 tips on developing a new (and lasting) habit. I then share with you 5 techniques for optimizing productivity, including a weekly and daily timebox planner t…
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In episode 59 I sit down with Rob Crews, founder and CEO of Complete Game, Player Development Company. We talk about improving mental strength, the importance of knowing and accepting yourself (as both an athlete and a person), the concept of human development instead of just player development, and the importance of being coachable. All of my visu…
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In episode 58 I sit down with Kiran Krishnan, microbiologist, researcher, co-founder of Microbiome Labs, and gut-health expert with 20 years of experience in nutrition and dietary supplements. In this episode, we discuss : What matters most when picking a probiotic (CFUs vs Strains) and why picking the right strain matters The importance of microbi…
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In this episode I have the great honor of interviewing someone I have admired for over 10-years. DR. Candice Esposito. Candice an expert in living calmly and navigating anxiety:In this episode we discuss: Overcoming anxiety through self-awareness and acceptance and how trauma and personal mis-alignment are the root of many illnesses. The healing tr…
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I'm delighted to be back with for episode 93 of Season Six of The One Thing podcast. This episode comes at an opportune time as many individuals are grappling with shifts in their mental well-being due to seasonal changes, alterations in weather, and fluctuations in the natural environment. There my be worsening ADHD, Anxiety, Depression, Autism, o…
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In episode 57 I sit down with Mike Crowson, owner of ARFUNNEL.io, Fit Legacy Marketing Agency. We discuss figuring out when and why is the right time to walk away from a business venture, redefining failure and success as an entrepreneur, finding balance between pursuing your passion and making it a full-time career, and the power of positive compo…
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