A Screen Printing and Apparel Decoration industry podcast, diving into a variety of niche topics with entrepreneurs from all backgrounds and interests. Whether you're looking for technical tips, business insights, or just some creative inspiration, "Let's Talk Shop with..." offers valuable knowledge and engaging discussions to help you elevate your screen printing game. Tune in and stay ahead in the vibrant and ever-evolving world of screen printing.
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SimNurseNZ - Conversations about all things simulation with Ali, Ez & Maz
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Welcome to Empowered Engineering, the podcast that brings you inside Empower's dynamic engineering world. Designed for curious problem-solvers and passionate technologists, we share our journey of innovation, collaboration, and continuous learning. Each episode aligns with the content pillars of our engineering blog: Technical Deep Dives: Explore complex technical challenges we've faced and the solutions we've developed, enriched with practical examples, code snippets, and real-world applica ...
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Anna Sale explores the big questions and hard choices that are often left out of polite conversation.
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RARECast is a Global Genes podcast hosted by award-winning journalist Daniel Levine. It focuses on the intersection of rare disease with business, science, and policy.
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The ways in which we work and scale workforces are changing. No longer are we reliant on a physical location in order to operate as a business or a team. This shift in building teams and companies is coming rapidly and businesses are being forced to adapt what they’ve done for years. In this podcast, we’ll be speaking to leaders and experts all over the world to dissect what makes businesses successful at remote working? We’ll be discussing the importance of human connection, emotional intel ...
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The tech news podcast with a comedic spin. Check out our website for more: https://whythetechpodcast.com/
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The show for creators, by creators. Helping inspire today's entrepreneurs to earn money from their own lemonade stand.
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Content marketing isn't just a channel anymore—it's the engine driving the entire marketing landscape, especially in B2B SaaS. Welcome to Content Blocks, the podcast designed specifically to unpack this monumental shift and equip early-stage SaaS startups with actionable strategies to build powerful content foundations. Hosted by Joe Michalowski, Content Blocks is your go-to resource for navigating the rapidly evolving world of B2B content. Why early-stage SaaS? Because that's where content ...
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From composer to screen: the journey of the orchestral score. We all know that the composer writes the music for a soundtrack, but what about all the people we don't see or hear about? Making A Soundtrack Season 2 shines a light on all of the people who contribute their time, energy and skill to bring an orchestral soundtrack to life.
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The Scientist’s LabTalk is a special edition podcast series produced by The Scientist’s Creative Services Team where we explore topics at the leading edge of innovative research.
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The Smart Life is a podcast looking at all things Smart Home and IoT. From the latest tech to the bigger questions around the role tech has to play in our lives, each episode, hosts Jess and Thomas will be joined by industry experts to break down the news behind the headlines.
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In this episode, we dive into the problem of B2B marketers trying to copy the success of content programs and series like Hot Ones. We look at the difference between gimmicks and concepts. And then look at the ins and outs of what makes the Hot Ones concept so successful. Originality, creativity, and enthusiasm all play a role. But you don't need a…
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The Patient and Cunning Work of Defending LGBTQ Rights with a Republican Supermajority
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56:14In West Virginia, Republicans hold one of the largest supermajorities in the country, and it’s growing. Just 11 Democrats — down from 14 last year — are in the 134-member Legislature. It's a political reality that isn't necessarily conducive to advancing LGBTQ rights. But that's Andrew Schneider's job. As head of Fairness West Virginia, Andrew has …
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In this episode, Joe shares insights on the right approach to SEO for companies that are just beginning. Key points include understanding the levels of SEO investment, the importance of laying a solid technical foundation, prioritizing bottom-funnel keywords, and building a comprehensive content strategy. Joe emphasizes that while advanced SEO tact…
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A Once-Failed Pain Therapy Shows Potential in a Neurodevelopmental Disorder
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32:48GRIN-related disorders are a group of rare neurodevelopmental conditions that can cause intellectual disability, behavioral challenges, and seizures. GRIN Therapeutics is developing a once-failed development candidate for chronic neuropathic pain, known as radiprodil, as a potential treatment for GRIN-related disorders driven by gain-of-function mu…
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In this episode, Joe Michalowski discusses the concept of 'content snowballs' in the SaaS industry, emphasizing the importance of long-term content strategies over immediate results. Drawing on insights from Jay Clouse's Creator Science podcast and an interview with James Clear, the author of 'Atomic Habits,' Joe explains how the visible success of…
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The 4 types of input engines for quality content at scale
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16:09In this episode, Joe Michalowski discusses the crucial role of quality inputs in creating impactful content, inspired by a Stephen King quote. He recounts his own journey from a novice freelance writer to a seasoned content creator, emphasizing the importance of gathering valuable insights. Four primary strategies for building robust input engines …
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Are Airline Pilots Allowed to Be Depressed?
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54:32To fly a plane, pilots must prove to the Federal Aviation Administration that they’re physically and mentally fit. But when it comes to mental health, the rules are complicated and, some say, outdated. Pilots who need antidepressants are limited to a short list of approved medications and must take a mandatory six-month leave. Even common diagnoses…
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This episode discusses Jon Hamm's career post-Mad Men and draws parallels to effective content marketing strategies. Despite perceptions, Hamm has been consistently working in various roles. Using Hamm's career as a metaphor, the talk emphasizes the importance of the 80/20 rule in content strategy—highlighting that while big, splashy moments (20%) …
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In this episode of Let’s Talk Shop, we sit down with the screen printing legend himself: Riley Hopkins. From building his first press in a San Francisco warehouse to losing millions and bouncing back, Riley shares a brutally honest, no-fluff story of innovation, risk, and perseverance. With nearly 50 years in the screen printing industry, Riley hel…
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Advancing a Cutting-Edge Therapy for a Rare, Childhood Cancer
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25:12Osteosarcoma is a rare and aggressive bone cancer that usually affects children and teenagers. Over the past 40 years, there’s been little progress to improve survival rates, with the five-year survival rate stagnant at about 60 to 70 percent for localized disease and 15 to 30 percent for metastatic osteosarcoma. OS Therapies is developing an exper…
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How the ‘Subway Takes’ Guy Became His Own Nepo Baby
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56:19Kareem Rahma, host of the viral web series Subway Takes, says he’s been working since he was 14 and hasn’t really taken a break. In high school, he worked service jobs. In college, he bought and re-sold motorcycles, jeans, and whatever else he thought he could flip. This week on the show, Kareem explains why he’s had so many jobs, including posts a…
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When Paul Biderman was born, he had trouble gaining weight. He grew sicker and, at about six months, he was diagnosed with the ultra-rare genetic disease abetalipoproteinemia, a condition that impairs a person’s ability to absorb fats and fat-soluble vitamins. The condition requires adherence to a strict diet and a regimen of daily vitamin suppleme…
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Scorpion Venom and Coffee Enemas Didn't Cure My Mother's Cancer
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44:18At a time when skepticism about conventional medicine has become even more mainstream, we’re revisiting a story about the causes and effects of that mistrust. Archie Matlow’s mother refused to get a surgery that could have saved her life, which led to her and Archie trying to love each other while bitterly at odds. You can listen to the full audio …
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(AI Gen) Removing Foreign Key Constraints against Hot Tables
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11:54A seemingly simple FK constraint drop turned into a high-stakes locking issue that threatened database stability. This post dives into the surprising chain reaction between two related tables and reveals a clever zero-downtime workaround using sp_rename. Perfect for engineers who love creative solutions to tricky schema changes—plus some spicy alte…
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The First Treatment for a Rare Neurodegenerative Condition Awaits FDA Approval
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24:16Spinocerebellar ataxia includes a group of rare, genetic, neurodegenerative disorders. People with the condition suffer from the loss of balance, coordination, and muscle control. As the condition progresses, people can lose the ability to walk and speak. There is no approved treatment for SCA, but Biohaven has applied to the U.S. Food and Drug Adm…
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Jane Tyerman and Marian Luctkar-Flude The CAN-Sim Co-Presidents
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1:01:32Jane Tyerman and Marian Luctkar-Flude The CAN-Sim Co-Presidents Season 2. Episode 8 In this episode of SimNurseNZ, we engage with Dr. Jane Tyerman and Dr. Marian Luctkar-Flude, Co-Presidents of the Canadian Alliance of Nurse Educators using Simulation (CAN-Sim). They share their personal journeys into the world of simulation, the inception and grow…
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Alongside life's darkest moments there often are moments of absurdity that make us laugh. In this episode, from a live San Francisco comedy festival in January, Anna and guests talk about the special kind of comedy born of something sad. Comedians Guy Branum and Carl Tart share stories of writing a sitcom about Zoom-era social relationships. Chanel…
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Let's Talk Shop with Jay from Threaded Ink
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1:17:07In this episode of Let's Talk Shop, we sit down with Jay, owner of Threaded Ink, to explore how he transitioned from a 21-year career in local government to running a thriving screen printing and heat transfer production business. Jay shares his journey of navigating the learning curve of DTF (Direct to Film) printing, overcoming challenges with eq…
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Joe Michalowski addresses the common concern of content marketers: "Do we have enough content?" He outlines a systematic approach to ideation, helping marketers continually generate strategic content by focusing on audience pain points and responsibilities. Key Discussion Points: 00:00 Introduction and Episode Overview 00:13 Is there such thing as …
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Engineering Skin Bacteria to Be Live Biotherapeutics
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28:27Netherton syndrome is a rare and chronic skin condition. One in ten infants with the disease will die as a result of infections and related complications. Azitra has developed a platform for engineering bacteria that naturally colonize the skin to produce proteins with therapeutic benefits to treat Netherton syndrome and other conditions. We spoke …
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A Middle-Aged Couple Made Porn to Spice Things Up. Then One of Them Got Fired.
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52:33When Joe Gow was fired from his position as chancellor and professor at the University of Wisconsin at La Crosse, his superiors said it was due to “abhorrent” behavior. Joe had made porn videos with his wife Carmen and uploaded them onto the internet under the name “Sexy Happy Couple.” This week, Joe and Carmen tell their side of the story and expl…
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Simple ways to approach positioning and messaging from a content seat
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16:35I explore the critical overlap between content marketing and product marketing, focusing specifically on positioning and messaging. Discover a straightforward approach for content marketers to quickly build effective positioning and messaging frameworks, even when official documentation is lacking. Key Discussion Points: 02:36 Building positioning …
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Seeing the Gene and Cell Therapy Translational Divide as an Opportunity
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33:58Emerging cell and gene therapies represent areas of great promise for people with rare, genetic diseases, but the translation gap for these medicines can leave them stalled at the lab. Mass General Brigham in 2022 launched the Gene and Cell Therapy Institute, a research hub dedicated to advancing gene and cell therapies for various diseases to brid…
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Life After Blowing It All Up: A Sugar Baby Story Revisited
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49:31In 2020, we made an episode about a listener who cheated on his wife with sex workers and was going through a divorce. He told us the idea to go on the website Seeking Arrangement came from an episode we made about sugar babies. A few weeks ago we called “Ethan” back to see what’s changed in his life since our first conversation, and how he navigat…
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You've found Content Blocks! However you made it here, I'm thrilled to have you. This is just a quick 5-minute memo from me where I introduce the idea behind Content Blocks, why I'm planning to focus on B2B SaaS content, and what you can expect from episodes moving forward. As a quick introduction of myself, my name is Joe Michalowski and I've been…
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Raziel Green lost both her mother and aunt to the rare neurodegenerative disease amyotrophic lateral sclerosis or ALS. But when Green, a runner, began experiencing muscle weakness and falls, doctors failed to recognize that she had a genetic form of the condition. Two years after she first sought care, she was diagnosed with the SOD1 form of the di…
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Anna talks to writer Ada Calhoun, author most recently of the novel Crush, about a married woman succumbing to extramarital temptation (she wrote it while she herself was separating from her husband) and then to comedian Rosebud Baker about her new Netflix comedy special, The Mother Lode, which is all about late-stage pregnancy and early motherhood…
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While traveling in Australia, Russ Walter was taken to the hospital and treated for heart palpitations. When he returned home, he soon lost the ability to walk. He was diagnosed with the rare autoimmune condition Guillian-Barre syndrome and spent three months in intensive care and rehabilitation. It would take nearly a year of physical therapy befo…
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From Uncertainty to Total Chaos, Your Stories About the New Trump Term
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55:14Since the inauguration in January, we’ve been getting emails and voice recordings from people whose lives have been thrust into uncertainty due to changes made by the Trump administration. Many federal workers and people who rely on federal money have lost their jobs. Others feel vulnerable and uncertain. This week, we’ll hear from a range of peopl…
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A Rapid and Scalable Approach for Screening Personalized ASOs
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23:56Organoids, three-dimensional cell models that can replicate an individual’s organs, are valuable tools for testing medicines that might treat their illness. It can, however, take up to $10,000 and a year to grow organoids using conventional methods from patient-derived induced pluripotent stem cells. Researchers at Children’s Mercy Kansas City’s Ge…
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Dr. Laura Newhouse on her 2 year Douglas Starship Simulation Programme Fellowship
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46:22Dr. Laura Newhouse on her 2 year Douglas Starship Simulation Programme Fellowship Season 2. Episode 7 Episode Summary: In this episode of SimNurseNZ, we had the privilege of sitting down with Dr. Laura Newhouse, who recently completed her two-year fellowship with the Douglas Starship Simulation Programme in Auckland, New Zealand. Dr. Newhouse share…
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(AI Gen) Embracing AI at Empower: Beyond Code Generation
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11:48Empower's engineering team is redefining what it means to use "the best tools" in a world where AI isn’t just a novelty, but a game changer. In his latest post, James Garrett shows how innovative AI tools are transforming on-call support, QA, and code reviews—taking the timeless principles of the Joel Test into the future. Dive in to see how early …
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I Was Ready to Write About My Domestic Abuser—Then Lawyers Said No.
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1:02:10When comedian Chelsea Devantez began writing her memoir, she knew exactly where to start: with a teenage relationship that spiraled into domestic violence. But when she submitted her draft, lawyers informed her she legally couldn't name her abuser or detail what happened. "I threw the book in the trash for a few months," Chelsea recalls. After cons…
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Addressing the Disease Mechanism of a Rare Kidney Disease
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25:52IgA nephropathy is a rare autoimmune kidney disease that can lead to the loss of kidney function. Though a number of treatment options exist today, none address the root cause of the disease and instead seek to manage symptoms, slow progression, or prevent complications. Vera Therapeutics’ experimental fusion protein atacicept, in a phase 2B study,…
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(AI Gen) EF Core N+1 Problem: Diagnosis and Solutions
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16:01Paul Gradie reveals how the notorious N+1 problem in EF Core—where seemingly simple data retrieval turns into a series of inefficient database trips—can be the hidden culprit behind performance woes. He breaks down how lazy loading and loops can lead to unnecessary queries, and shares actionable fixes to streamline your code. Dive in to uncover tip…
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Six and a half years ago, in the wake of the #MeToo movement, we asked our listeners how they think about manhood–how to be, what’s hard, where they feel lost. Fast forward to 2025, and the norms and trends around manhood are even more varied and complicated. So we thought it would be a good time to revisit the stories from 2018 and provide updates…
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Let's Talk Shop with Victor from OmniPrint
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47:17Welcome back to another episode of Let’s Talk Shop! 🎙️ Today, Brandon sits down with Victor Peña, the founder and CEO of OmniPrint International, to dive deep into the world of garment decoration, digital printing, and business growth. 💡 Victor shares his journey—from his early days in engineering to building a global brand in direct-to-garment (DT…
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The Mother of a Son with SCD, Applies Direct Experience to Her Clinical Trials Work
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38:42When Katrina Rice’s son was diagnosed with the rare, hematological disorder sickle cell disease, she got to spend a lot of time understanding how a rare disease affects the daily life of people with a condition and their caregivers. Her son, now 28, has become a participant in clinical trials, and that’s further broadened Rice’s perspective as chie…
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After Sobriety, Chasing Goosebumps Instead of Highs
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49:07When the poet and writer Kaveh Akbar likes something, he really likes it. As a high school student, he got hooked on poetry. In college, it was alcohol. This week, Kaveh talks to Anna Sale about the factors that led to his sobriety, and he explains exactly how he manages a life that’s full of healthy, wonderful obsessions as well as problematic one…
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A First for Rett Syndrome with More in the Pipeline
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23:07In 2023, Acadia Pharmaceuticals won approval for Daybue, the first and only treatment for the rare, neurodevelopmental disorder Rett syndrome. Daybue is not a cure and Acadia continues to pursue additional therapies for the condition including an antisense oligonucleotide therapy to upregulate a protein people with Rett syndrome lack. We spoke to E…
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The “Chest-Clenching Fear” of My Ex-Husband’s Jan 6 Commutation
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58:36In 2023, Anna and On The Media’s Micah Loewinger traveled to Montana to talk to Tasha Adams, the ex-wife of Stewart Rhodes, who founded the far-right paramilitary group, the Oath Keepers. Stewart had been charged with seditious conspiracy for his participation in the January 6 Capitol riots, and Tasha was eagerly awaiting sentencing: “I need him to…
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Lydia Lofton on Interprofessional Education (IPE)
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39:18SimNurseNZ Interviews Lydia Lofton Season 2. Episode 7 Episode Summary: In this episode of the SimNurseNZ podcast, we’re joined by Lydia Lofton, Associate Director at NHS Elect, to explore her fascinating journey into simulation and its transformative impact on her career. Lydia’s extensive experience in the world of healthcare simulation, coupled …
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A Heart Attack that Led to a Rare Disease Diagnosis
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30:13When Patty Keating had her thyroid removed, she experienced what she described as a “buzzing in her face,” had trouble sleeping, and felt anxious. Her symptoms grew worse and she had trouble climbing stairs. Then, six months later, her heart started racing, and her husband rushed her to the hospital, where tests showed she was having a heart attack…
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Comedian Gary Gulman is used to dealing with bullies. He grew up with older brothers, who he describes as "aggressive" and “unenlightened,” and he’s witnessed plenty of unkind behavior from his peers in the New York City comedy scene. This is all despite being, in his words, “very, very sensitive.” This week, Gary talks about managing that sensitiv…
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Targeting Rare Liver Diseases with Gene Editing Therapies
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23:33Earlier this year iECURE reported that an infant with the rare and deadly liver disease OTC deficiency had a complete response to its experimental gene editing therapy. It is believed to be the time that an infant was treated with an in vivo, liver-directed gene editor. The treatment restored ammonia levels in the child’s blood to normal and the ch…
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‘Babygirl’ Director Wants Women Not to Suppress Their Beast
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58:05Babygirl, the new erotic thriller starring Nicole Kidman, features an age-gap romance and a power imbalance. But according to the filmmaker Halina Reijn, it’s more about “what part of us is civilized…and what part of us is still driven by primal forces.” It’s also extremely entertaining, sexy, and dryly hilarious. This week, Halina Reijn talks abou…
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(AI Gen) Building Bonds Beyond the Screen
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13:30Onsites are crucial for remote teams to build strong bonds and a thriving company culture. While remote work offers flexibility and efficiency, in-person gatherings provide unique opportunities to deepen relationships, foster collaboration, and align on shared goals. Empower, a fully remote company, has successfully integrated onsites into their wo…
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Using AI to De-Risk Rare Disease Drug Development
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43:37Healx, which developed an AI platform to repurpose drugs for rare diseases, is among the first generation of companies built on an AI drug discovery engine. The company’s lead experimental therapy, which the U.S. Food and Drug Administration granted Fast Track designation to in October 2024, is in mid-stage development for neurofibromatosis type 1,…
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Paid to Care: When Class, Power, and Caregiving Collide
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51:43When Delores moved to New York City from Jamaica nearly thirty years ago she didn’t know anyone. But soon she found a community of other nannies and learned how to navigate job interviews and “fussy” parents who don’t like nannies to tell their children no. In this week’s episode on paid caretaking, we explore the class and power dynamics inherent …
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Addressing a Growing Demand for Plasma-Derived Therapies
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30:39Primary immunodeficiency disorders include more than 400 conditions, and a growing number of people are being recognized as having them as a result of improved diagnostic tools and greater awareness among physicians. Most treatments for these conditions are plasma-derived therapies sourced from donors. We spoke to Joerg Schuettrumpf, chief scientif…
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