Best SelfDecode Podcasts (2025)

1
How DNA Data is Revolutionizing Personalized Medicine with Sasha Powell 1:08:37

3d ago1:08:37

1:08:37

In this episode of the Joe Cohen Show, host Joe Cohen discusses the power of biohacking and precision health with Sasha Powell, a nurse practitioner and integrative healthcare provider. Sasha shares her experience using DNA data to optimize her patients' health outcomes, focusing on areas like hormone and weight management, mental health, and overa…

1
Understanding Glutamate: Anxiety, OCD, and Brain Health 22:43

6d ago22:43

22:43

In this solo episode, Joe Cohen explores the powerful effects of glutamate on the brain and how elevated levels can drive anxiety, obsessive thoughts, and overstimulation. He shares insights from personal experiments with supplements like AKG, proline, and arginine and explains how they impacted his mental state, motivation, and focus. Joe also bre…

1
The Truth About Microbiome Testing with Kiran Krishnan 54:40

10d ago54:40

54:40

In this eye-opening episode of The Joe Cohen Show, Joe sits down with microbiologist and biotech entrepreneur Kiran Krishnan to dismantle the myths and marketing hype surrounding microbiome testing. Drawing parallels between the DNA and microbiome industries, they expose the scientific shortcuts, technological flaws, and misleading health claims be…

1
The DNA Testing Industry Is Broken. Here's What We're Doing About It 9:17

13d ago9:17

9:17

Most genetic testing companies promise personalized health insights, but their reports barely scratch the surface, often analyzing just a handful of genetic variants. In this episode, Joe Cohen shares what happened when the SelfDecode team took a close look at dozens of these reports to understand how and why they fall short and what it actually ta…

1
The Future of Personalized Health and Nutrition with Mark Notton 33:08

17d ago33:08

33:08

In this episode, Joe Cohen talks with Mark Notton, founder of Revive DNA, about how your DNA can shape your sleep, energy, and long-term health. After helping his wife recover from a chronic autoimmune condition using a personalized nutrition approach, Mark left his executive career at Samsung to launch a health tech company. Now, Revive DNA is mak…

1
Should You Take This? L. Plantarum for Bloating, Brain Fog & Inflammation 20:50

20d ago20:50

20:50

In this episode, Joe discusses the benefits of the probiotic L. Plantarum, specifically the 299V strain. He talks about its effectiveness in reducing gas, improving mood, exercise recovery, and more. He shares how he personalizes his probiotic routine using SelfDecode, why the specific strain matters more than the brand, and how he takes higher dos…

1
Unlocking Longevity: Biohacking, DNA Testing & Stress Management w/ Martin Kremmer 46:20

25d ago46:20

46:20

Join Joe Cohen in this insightful episode as he interviews Martin Kremmer, CEO and co-founder of BioWatch and FreeAge. Martin, a pioneer in the Danish biohacking scene, shares his company's innovative approach to DNA and epigenetic testing to develop personalized longevity plans. They discuss the importance of combining different types of data, the…

1
The Truth About Bryan Johnson’s Blueprint: What Works & What Doesn’t 1:05:47

27d ago1:05:47

1:05:47

Is Bryan Johnson’s anti-aging regimen the ultimate blueprint for health, or just another one-size-fits-all approach? In this episode, Joe Cohen breaks down Johnson’s protocol, highlighting what works, what doesn’t, and why personalization is key. Joe shares his own experiences and expert insights to help you optimize your health on your own terms. …

1
The Future of Regenerative Medicine: Stem Cells, Exosomes & Anti-Aging Breakthroughs with Dr. Brigitte Hanly 1:02:15

1M ago1:02:15

1:02:15

In this episode, Joe Cohen sits down with Dr. Brigitte Hanly, CEO, Chief Scientist, and co-founder of Stemaid Institute, to explore the cutting-edge world of stem cell therapy. They discuss how pluripotent stem cells and exosomes can optimize health, repair injuries, and even slow aging. Joe shares his firsthand experience with the treatments, incl…

1
Should You Take This? The Surprising Benefits of L. Reuteri for Gut Health, Immunity & More 13:30

1M ago13:30

13:30

Can a single probiotic strain transform your gut, lower cholesterol, and even help with food sensitivities? In this episode of The Joe Cohen Show, we dive into the fascinating research behind Lactobacillus reuteri. Joe shares his personal experiments and breaks down the science on how L. reuteri may support digestion, reduce inflammation, and even …

1
Overcoming Chronic Migraines and Fatigue with Dr. Elena Gross 1:07:07

1M ago1:07:07

1:07:07

Dr. Elena Gross joins Joe Cohen to share her journey from debilitating chronic migraines to becoming a neuroscience researcher and entrepreneur. They explore the role of mitochondrial dysfunction in migraines, how ketosis can optimize brain energy, and the importance of personalized health approaches. Joe and Elena break down the science behind oxi…

1
Why the Genova NutrEval Test Falls Short (Honest Review) 30:36

1M ago30:36

30:36

In this episode of The Joe Cohen Show, Joe shares his honest review of the Genova NutrEval FMV amino acids test. He discusses the challenges of interpreting the results, the differences between urine and blood samples, and key insights related to antioxidant support, mitochondrial function, and nutrient needs. Considering the NutrEval test? This ep…

1
What is EFT? The Simple Technique That Can Transform Your Life with Brad Yates 58:12

2M ago58:12

58:12

What if a simple technique could break down mental barriers, eliminate stress, and unlock peak performance? Meet Brad Yates, the legendary "EFT Wizard," whose tapping techniques have transformed millions of lives. In this episode, Joe sits down with Brad to reveal how Emotional Freedom Techniques (EFT) can help you clear emotional blocks, optimize …

1
The Truth About GLP-1 & Ozempic: Natural Hacks for Weight Loss & Blood Sugar Control 22:25

2M ago22:25

22:25

Are you curious about the science behind GLP-1 agonists like Ozempic? Want to know how you can naturally support weight loss and blood sugar regulation without relying on medication? In this episode of The Joe Cohen Show, we dive deep into the world of GLP-1, exploring natural alternatives that can help suppress hunger, enhance metabolism, and opti…

1
Whole Genome Sequencing & The Future of Health with Dr. Puya Yazdi 44:49

2M ago44:49

44:49

Is the genetics industry full of BS? Joe Cohen sits down with Dr. Puya Yazdi, co-founder of SelfDecode, to expose the real science behind genetic testing, polygenic risk scores, and why most DNA reports are giving you half-truths (or worse—total garbage). If you care about your health, longevity, and actually understanding what your genes say about…

1
Should You Take This? L. fermentum – Immunity, Glutathione and Inflammation 14:27

2M ago14:27

14:27

In this episode of The Joe Cohen Show, Joe dives into the world of probiotics and biohacking with a deep dive into Lactobacillus fermentum. He shares his personal experience megadosing this unique probiotic, which has been linked to boosting glutathione levels—one of the body's most powerful antioxidants. Joe discusses the science behind L. ferment…

1
A Deep Dive into Wild Health & DNA Analysis 19:25

2M ago19:25

19:25

In this episode of The Joe Cohen Show, we take a deep dive into genetic reports, specifically analyzing the Wild Health Report. Joe breaks down the strengths and weaknesses of these reports, highlighting the common pitfalls in genetic testing and how they often analyze only a limited set of variants. He also introduces a new and improved alternativ…

1
Choosing the Best Air Purifier And Why It Matters 18:09

2M ago18:09

18:09

In this episode of The Joe Cohen Show, Joe explores the science of air purification and why investing in the right air purifiers and air filters is essential for optimizing health. He breaks down how poor indoor air quality—filled with mold spores, VOCs, and airborne pollutants—can impact energy levels, cognitive function, and inflammation. Joe sha…

1
Biohacking for Women: Melanie Avalon on Optimizing Health & Performance 1:25:46

2M ago1:25:46

1:25:46

Join host Joe Cohen as he sits down with biohacker, actress, and health influencer Melanie Avalon for an insightful discussion on women and biohacking. Melanie shares her top biohacks, secrets to boosting performance, and even some surprising drinking biohacks. As the host of multiple health-focused podcasts, founder of AvalonX, and author of What,…

1
Should You Take This? L. Rhamnosus – GABA, Mood, and Heart Health 23:33

2M ago23:33

23:33

In this episode of Should You Take This?, host Joe Cohen dives deep into Lactobacillus rhamnosus GG (L. Rhamnosus GG)—one of the most researched probiotic strains for gut health, brain function, and heart health. Joe shares his megadosing experiment, where he took 375 billion CFU of L. Rhamnosus in one day—25x the standard dose—to test its effects …

1
Should You Take This?: B. Longum – The Probiotic for Gut & Brain Health 12:57

2M ago12:57

12:57

In this episode of Should You Take This?, host Joe Cohen dives deep into one of his top three favorite probiotics—Bifidobacterium longum. If you've struggled with bloating, digestion issues, or simply want to optimize your gut health, this probiotic might be a game-changer. Joe shares his personal experience with B. longum, breaking down its effect…

1
The Truth Behind 10X Health - DNA Deceptions #02 14:58

4M ago14:58

14:58

Join Joe Cohen in the second episode of the DNA Deceptions series, where he takes a hard look at the world of DNA and genetic testing. In this episode, Joe shares his unfiltered thoughts on 10x Genetics, explaining why he believes it’s one of the worst products in the genetic testing market. From questionable marketing tactics to flawed science, th…

1
Why 3x4 Genetics' Functional Approach Falls Short - DNA Deceptions #01 22:29

4M ago22:29

22:29

In the first episode of the DNA Deception series, Joe Cohen takes a critical look at 3x4 Genetics and their functional approach to DNA testing. With an emphasis on the science and practical applications, Joe explains why this method often fails to meet expectations. Whether you're exploring DNA-based health solutions or simply curious about genetic…

1
Best of Season 7: Highlights & Health-Changing Moments from Experts 39:22

7M ago39:22

39:22

In this special "Best of Season 7" episode, we’re revisiting the most impactful, inspiring, and thought-provoking moments from our standout interviews this season. From groundbreaking health hacks and personal growth strategies to expert insights on optimizing your life, these are the clips that sparked the biggest conversations. Whether you're a l…

1
Digital Detox, Cutting-Edge Therapies, and Unique Biohacking Tricks with Jack Smith 1:26:09

8M ago1:26:09

1:26:09

In this episode Joe sits down with Jack Smith, known for his pioneering biohacking experiments. Jack shares his biohacking journey, highlighting unique health devices like the Pulse PEMF machine, EES cube, Altwork desk, and Oura Ring. He also delves into therapies such as ketamine for mental wellness, GAINSWave, and resistant starch for gut health.…

1
Revitalize Your Love Life: Mastering Intimacy with Dr. Saida Desilet And Aaron Michael 1:06:27

8M ago1:06:27

1:06:27

In this episode, Aaron Michael and Dr. Saida Desilet discuss practical tips for enhancing intimacy, overcoming common sexual challenges, and sustaining long-term passion. Gain insights from their combined 50 years of experience in revolutionizing sex coaching, relationships, and intimacy. Learn about natural methods to boost sexual health, the impa…

1
The Mechanisms of Aging and How To Reduce Your Biological Age | Chris Mirabile 1:06:27

8M ago1:06:27

1:06:27

In this episode, Joe sits down with Chris Mirabile, founder and CEO of Novos Labs, to explore cutting-edge strategies for reducing your biological age and slowing the pace of aging. Chris shares his personal journey and the science behind his success, diving into the mechanisms of aging and the powerful supplements that can make a difference. They …

1
Enhance Sexual Performance and Satisfaction: Discovering The Adamo Method with Molly Maloof 1:09:39

8M ago1:09:39

1:09:39

In this episode, Dr. Maloof reveals her biohacking strategies to revolutionize your sex life, just as you would your nutrition and fitness. Discover research-backed practices and expert insights that go beyond the basics, helping you elevate your intimate experiences and achieve a healthier, more fulfilling life. As the founder and CEO of Adamo Bio…

1
Dr. Gerald Pollack: How to Create The Perfect Water For Optimal Health | Throwback Episode #03 1:45:39

9M ago1:45:39

1:45:39

This episode was originally published on May 22, 2015. Join Joe in an engaging interview with Dr. Gerald Pollack, a distinguished professor from the University of Washington, as they explore the groundbreaking concept of EZ water, also known as the fourth phase of water. Discover its unique properties, health benefits, and interaction with factors …

1
Unlocking the Secrets of Heart Rate Variability with Dr. Andrew Ahn 45:20

9M ago45:20

45:20

In this episode, Joe interviews Dr. Andrew Ahn, an internal medicine physician and expert in physiological signal analysis. The central topic of discussion is Heart Rate Variability (HRV). Dr. Ahn describes various measures of HRV, including time-domain, frequency-domain, and nonlinear analysis. He shares insights into personal HRV tracking and the…

1
Dr. Alan Bauman | Understanding Hair Loss, Healthy Hair, and Effective Regrowth Strategies 1:08:37

9M ago1:08:37

1:08:37

In this episode, Joe dives deep into the world of hair loss and hair growth treatments with Dr. Alan Bauman, a leading hair restoration physician. With over 33,000 patients treated and 12,000 hair transplant procedures performed, Dr. Bauman shares his expertise on various treatments like PRP, FUE, Regenera, and even microneedling. The discussion co…

1
Unlocking Health Secrets with Organic Acids Tests: Elizma Lambert's Expert Insights (Part 3) 36:32

9M ago36:32

36:32

In this third and final part of our series with Elizma Lambert, we dive deep into the world of biohacking, exploring the latest technology, supplements, and research. Join us as Elizma Lambert shares her expertise on optimizing both body and brain health, providing actionable tips and strategies for achieving peak performance. In this episode, you'…

1
Improve Your Health With These Organic Acids Markers w/ Elizma Lambert (Part 2) 49:07

9M ago49:07

49:07

This is the second episode of a three-part series with Elizma Lambert, where we delve into the world of the Organic Acids Test (OAT) and its crucial role in optimizing health. In this episode, Elizma explores an array of biochemical markers, including yeast and fungal indicators, bacterial markers, oxalate metabolites, Candida overgrowth, thyroid f…

1
Everything You Need to Know About Organic Acids Test (OAT) with Elizma Lambert: Discussing Candida (Part 1) 41:12

10M ago41:12

41:12

This is the first episode of a three-part series with Elizma Lambert, where we delve into the world of the Organic Acids Test (OAT) and its crucial role in optimizing health. In this episode, we get started on our analysis of Organic Acids Test (OAT) and its essential role in naturopathic medicine and precision health. Elizma Lambert, a seasoned ex…

1
Dr. Michael Snyder | How To Boost Your Longevity with Precision Medicine 1:05:41

10M ago1:05:41

1:05:41

In this episode, we dive deep into the world of precision health with Dr. Michael Snyder, a renowned professor of genetics at Stanford University and the chair of the genetics department. Join us as Dr. Snyder shares his groundbreaking insights on the latest advancements in precision medicine, biohacking, and personalized healthcare. Discover how c…

1
Biohacking, Fitness and Longevity with Jean Fallacara 47:55

11M ago47:55

47:55

In this episode, Joe speaks with Jean Fallacara, a multifaceted entrepreneur, neuroscientist, and calisthenics enthusiast. Jean shares insights on how he maintains peak performance through biohacking, focusing on supplements, exercise routines, and meditation practices. Joe and Jean dive deep into the realms of precision health, genetic testing, an…

1
How Proline Can Make You A Hypochondriac | Supplement Deep Dive 12:08

11M ago12:08

12:08

In this episode, Joe dives into the complex world of proline supplementation. He discusses the impacts proline has on collagen synthesis, aiming for improved skin health, enhanced wound healing, and better exercise recovery. However, the journey took an unexpected turn as Joe explains the biomechanics behind why he experienced several side effects …

1
Can This Outperform Caffeine for Better Focus? | Supplement Deep Dive 18:13

11M ago18:13

18:13

Join Joe as he takes a closer look at saffron, a spice revered not just for its flavor but for its impressive health benefits. In this deep dive, Joe explores how saffron could potentially outshine caffeine in enhancing mental clarity and focus. This episode goes in-depth on how saffron impacts various aspects of health, from improving sleep qualit…

1
Decrease Your Heavy Metals by 75% With This Supplement | Supplement Deep Dive 24:16

11M ago24:16

24:16

Join Joe as he delves into his journey with MSM (Methyl Sulfonyl Methane) supplementation, a key to detoxing the body and enhancing recovery. In this episode, Joe discusses: The Impact of Heavy Metals on Health: Understanding the dangers of heavy metals and the importance of detoxing them from our bodies. MSM as a Detox & Methylation Aid: How MSM s…

1
Resistant Starch vs. Ozempic: A Natural Path to Weight Loss and Cognitive Boost | Supplement Deep Dive 17:28

12M ago17:28

17:28

Buy Jo’s Resistant Starch on Amazon Join Joe as he explores the powerful benefits of resistant starch as a natural alternative to Ozempic. In this episode, Joe dives into how resistant starch not only supports weight management and cognitive function but also promotes gut health—all without the side effects associated with pharmaceutical options li…

1
Dr. Ritamarie on Integrating Personalized Health Into Your Daily Life 47:12

12M ago47:12

47:12

In this episode, Joe has an in-depth conversation with Dr. Rita Marie, a licensed doctor of chiropractic and the founder of the Institute of Nutritional Endocrinology, about the importance of personalized healthcare in addressing insulin, thyroid, adrenal, and digestive imbalances through the integration of genetics and lifestyle changes. Dr. Rita …

1
Can AKG Make You Anxious?: The Pros & Cons of This Longevity Supplement 14:40

12M ago14:40

14:40

In this episode, Joe dives deep into the effects of megadosing AKG (Alpha Ketoglutarate), a crucial supplement in metabolic pathways and its implications for longevity. Discover the risks and rewards as Joe recounts increasing his AKG intake to 15 times the standard dosage, leading to notable side effects such as enhanced anxiety and sleep issues. …

1
How Betaine and BHMT Influence Your Methylation | SNPit #19 5:01

12M ago5:01

5:01

In this episode, we delve into the pivotal role of the BHMT gene within the body's methylation process. We discuss how the BHMT enzyme is essential for catalyzing a vital reaction that transforms homocysteine into methionine. Additionally, we cover the importance of betaine in enhancing the methylation cycle. Betaine acts as a methyl donor, particu…

1
Is Niacin Killing You?: Breaking Down The New Niacin Study 27:22

1y ago27:22

27:22

In this episode, Joe tackles a controversial new study that suggests even 25 milligrams of niacin could potentially increase the risk of heart disease. Delving deep into the world of niacin supplementation, Joe discusses how, despite these concerns, niacin offers numerous health benefits, including enhanced cognitive function, better mood, and incr…

1
The Science of Cannabinoids and the CNR1 Gene | SNPit #18 5:52

1y ago5:52

5:52

In this episode, we explore the complex interplay between the CNR1 gene, cannabinoid receptors, and cannabis. Discover the role of the endocannabinoid system in maintaining bodily balance, particularly in brain function, mood regulation, and inflammation response. We delve deep into how genetic variations in the CNR1 gene can influence the CB1 rece…

1
Balance Serotonin and Decrease Anxiety With The HTR1A & HTR2A Genes | SNPit #17 7:13

1y ago7:13

7:13

In this episode, we explore the crucial role of serotonin in managing anxiety and enhancing mental wellbeing. Discover how serotonin not only influences mood but also plays a pivotal role in anxiety regulation and mental health. Learn about the HTR1A and HTR2A genes, which act like switches, controlling the serotonin levels in the brain. Understand…

1
Q&A #03 - Answering Questions About SelfDecode 25:24

1y ago25:24

25:24

In this episode, Joe takes questions from SelfDecode members, answering questions like: What makes SelfDecode different from other DNA companies? How does the recommendations engine work? Can you find out if a certain supplement is right for you? Plus, he shares some of his genetic predispositions and how they correlate with his lab levels! - Check…

1
MTHFD1, Choline and Methylation | SNPit #16 6:01

1y ago6:01

6:01

In this episode, we delve into the critical process of methylation, highlighting its significant impact on health issues ranging from heart disease to mental health and focusing on a lesser known methylation gene - MTHFD1. We focus on the MTHFD1 gene and choline's significance beyond methylfolate and Vitamin B12 for undermethylators. Discover how M…

1
Dr Jack Kruse On Biohacking Your Water, EMFs, Blue Light, DHA, Cold, Sun and Sleep | Throwback Episode #02 2:00:17

1y ago2:00:17

2:00:17

This episode was originally published on April 12, 2015. Dr. Jack Kruse and Joe explore unconventional approaches to health through the lens of physics and biochemistry. They cover topics like the critical roles of mitochondrial function, environmental factors such as EMFs, blue light, and dietary choices on our well-being, and challenge common hea…

1
Dopamine, Serotonin, Norepinephrine, and MAOB | SNPit #15 5:59

1y ago5:59

5:59

In this episode, we delve into the science behind the MAOB gene and monoamine neurotransmitters. Join us as we explore the crucial role of dopamine, serotonin, and norepinephrine in regulating mood and cognition. We dissect the function of the MAOB gene in metabolizing neurotransmitters and discuss the implications of genetic variations on mental h…

Podcasts Worth a Listen

SelfDecode Podcasts

Podcasts Worth a Listen

Quick Reference Guide